754
Views
5
CrossRef citations to date
0
Altmetric
Review Articles

Research Progress on Multifunctional Fluorescent Probes for Biological Imaging, Food and Environmental Detection

&
Pages 775-817 | Published online: 18 Jul 2022

References

  • Yan, Y.; Lian, K.; Zhang, H.; An, J.; Zhang, Y.; Kang, W.; Ai, L. Doping-Control Analysis of 14 Diuretics in Animal-Derived Foods Using Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry. Microchem. J. 2022, 174, 106948. DOI: 10.1016/j.microc.2021.106948.
  • Zianni, R.; Mentana, A.; Campaniello, M.; Chiappinelli, A.; Tomaiuolo, M.; Chiaravalle, A. E.; Marchesani, G. An investigation using a validated method based on HS-SPME-GC-MS detection for the determination of 2-dodecylcyclobutanone and 2-tetradecylcyclobutanone in X-ray irradiated dairy products. LWT–Food Sci. Technol. 2022, 153, 112466. DOI: 10.1016/j.lwt.2021.112466.
  • Gencer, O.; Çeven, Ö. F.; Ünlü, C. Triggering Excitation Independent Fluorescence in Zinc(II) Incorporated Carbon Dots: Surface Passivation of Carbon Dots with Zinc(II) Ions by Microwave Assisted Synthesis Methods. Diam. Relat. Mater. 2022, 123, 108874. DOI: 10.1016/j.diamond.2022.108874.
  • Chen, C. P.; Wu, C. Y.; Chern, S. R.; Chen, S. W.; Wu, F. T.; Lee, M. S.; Wang, W. Rapid Diagnosis of Trisomy 13 of Maternal Origin by Quantitative Fluorescent Polymerase Chain Reaction Analysis in a Pregnancy with Fetal Holoprosencephaly, Premaxillary Agenesis, Postaxial Polydactyly of Left Hand and Overriding Aorta. Taiwan J Obstet Gynecol. 2021, 60, 903–904. DOI: 10.1016/j.tjog.2021.07.020.
  • Jeber, J. N.; Hassan, R. F.; Hammood, M. K.; Al-Jeilawi, O. H. R. Sensitive and Simple Colorimetric Methods for Visual Detection and Quantitative Determination of Semicarbazide in Flour Products Using Colorimetric Reagents. Sens. Actuators B. 2021, 341, 130009. DOI: 10.1016/j.snb.2021.130009.
  • Feng, Y.-A.; Xu, H.; Zhou, Y.; Wang, B.-J.; Xiao, J.; Wang, Y.-W.; Peng, Y. Ratiometric Detection and Bioimaging of Endogenous Alkaline Phosphatase by a NIR Fluorescence Probe. Sens. Actuators B. 2022, 358, 131505. DOI: 10.1016/j.snb.2022.131505.
  • Yin, H.; Chi, H.; Shang, Z.; Qaitoon, A.; Yu, J.; Meng, Q.; Zhang, Z.; Jia, H.; Zhang, R. Development of a New Water-Soluble Fluorescence Probe for Hypochlorous Acid Detection in Drinking Water. Food Chem (Oxf). 2021, 2, 100027. DOI: 10.1016/j.fochms.2021.100027.
  • Sun, Y.; Zhang, L.; Zhang, H.; Zhang, Y.; Sun, B. Effects of Two Sterilization Methods on the Taste Compositions of Sweet and Sour Spare Ribs Flavor. J. Food Compos. Anal. 2021, 104, 104143. DOI: 10.1016/j.jfca.2021.104143.
  • Wang, B. J.; Liu, R. J.; Fang, J.; Wang, Y. W.; Peng, Y. A Water-Soluble Dual-Site Fluorescent Probe for the Rapid Detection of Cysteine with High Sensitivity and Specificity. Chem Commun (Camb). 2019, 55, 11762–11765. DOI: 10.1039/c9cc06468k.
  • Geng, Y.; Chen, L.; Wan, Q.; Lian, C.; Han, Y.; Wang, Y.; Zhang, C.; Huang, L.; Zhao, H.; Sun, X.; He, H. A Novel [1,2,4]Triazolo[1,5-a]Pyrimidine Derivative as a Fluorescence Probe for Specific Detection of Fe3+ Ions and Application in Cell Imaging. Anal Chim Acta. 2021, 1187, 339168. DOI: 10.1016/j.aca.2021.339168.
  • Gao, Z.; Zhang, L.; Liu, H.; Yan, M.; Lu, S.; Lian, H.; Zhang, P.; Zhu, J.; Jin, M. A Novel Rhodol-Based Fluorescence Turn-on Probe for Selective Hydrogen Sulfide Detection in Environment Water and Living Cells. J. Photoch. Photobio. A. 2022, 423, 113598. DOI: 10.1016/j.jphotochem.2021.113598.
  • Duan, N.; Wang, H.; Li, Y.; Yang, S.; Tian, H.; Sun, B. The Research Progress of Organic Fluorescent Probe Applied in Food and Drinking Water Detection. Coordin. Chem. Rev. 2021, 427, 213557. DOI: 10.1016/j.ccr.2020.213557.
  • Duan, N.; Yang, S.; Tian, H.; Sun, B. The Recent Advance of Organic Fluorescent Probe Rapid Detection for Common Substances in Beverages. Food Chem. 2021, 358, 129839. DOI: 10.1016/j.foodchem.2021.129839.
  • Du, L.; Xie, Y.; Qian, H.; Zhou, W.; Yang, Q.; Sun, X.; Wang, L. A New Coumarin-Based “Turn-on” Fluorescence Probe with High Sensitivity and Specificity for Detecting Hypochlorite Ion. Dyes Pigm. 2022, 200, 110137. DOI: 10.1016/j.dyepig.2022.110137.
  • Talesh Ramezani, A.; Rabiei, R.; Badiei, A.; Mohammadi Ziarani, G.; Ghasemi, J. B. A New Fluorescence Probe for Detection of Cu + 2 in Blood Samples: Circuit Logic Gate. Anal Biochem. 2022, 639, 114525. DOI: 10.1016/j.ab.2021.114525.
  • Hao, Y.; Li, Z.; Ding, N.; Tang, X.; Zhang, C. A New near-Infrared Fluorescence Probe Synthesized from IR-783 for Detection and Bioimaging of Hydrogen Peroxide in Vitro and in Vivo. Spectrochim Acta A Mol Biomol Spectrosc. 2022, 268, 120642. DOI: 10.1016/j.saa.2021.120642.
  • Lei, X.; Zou, Y.; Liang, Q.; Xu, W.; Lao, S.; Yang, B.; Li, L.; Yang, L.; Liu, H.; Ma, L.-J. An Ultrasensitive 4-(Diethylamino) Salicylaldehyd-Based Fluorescence Enhancement Probe for the Detection of Al3+ in Aqueous Solutions and Its Application in Cells. J. Photoch. Photobio. A. 2022, 428, 113854. DOI: 10.1016/j.jphotochem.2022.113854.
  • Gao, Z.; Qiu, S.; Yan, M.; Liu, H.; Lu, S.; Lian, H.; Zhang, P.; Zhu, J.; Jin, M. A Novel Xanthene-Based Fluorescence Turn-on Probe for Highly Selective Detection of Hg2+ in Water Samples and Living Cells. J. Mol. Struct. 2022, 1254, 132312. DOI: 10.1016/j.molstruc.2021.132312.
  • Wang, X.-B.; Li, H.-J.; Liu, C.; Lu, W.-Y.; Lu, X.; Wu, Y.-C. A Water-Soluble Turn-on Fluorescent Probe for Rapid Discrimination and Imaging of Cys/Hcy and GSH in Cells and Zebrafish through Different Fluorescent Channels. Dyes Pigm. 2022, 199, 110058. DOI: 10.1016/j.dyepig.2021.110058.
  • Jiang, L.; Chen, T.; Song, E.; Fan, Y.; Min, D.; Zeng, L.; Bao, G.-M. High-Performance near-Infrared Fluorescence Probe for Fast and Specific Visualization of Harmful Sulfite in Food, Living Cells, and Zebrafish. Chem. Eng. J. 2022, 427, 131563. DOI: 10.1016/j.cej.2021.131563.
  • Jin, H.; Yang, M.; Sun, Z.; Gui, R. Ratiometric Two-Photon Fluorescence Probes for Sensing, Imaging and Biomedicine Applications at Living Cell and Small Animal Levels. Coordin. Chem. Rev. 2021, 446, 214114. DOI: 10.1016/j.ccr.2021.214114.
  • Gui, R.; Jin, H.; Bu, X.; Fu, Y.; Wang, Z.; Liu, Q. Recent Advances in Dual-Emission Ratiometric Fluorescence Probes for Chemo/Biosensing and Bioimaging of Biomarkers. Coordin. Chem. Rev. 2019, 383, 82–103. DOI: 10.1016/j.ccr.2019.01.004.
  • X.; Nan, Y.; Huyan, H.; Li, S.; Sun, Y.; Xu, 4. Reaction-Based Fluorescent Probes for Hg2+, Cu2+ and Fe3+/Fe2+. Coordin. Chem. Rev. 2021, 426, 213580. DOI: 10.1016/j.ccr.2020.213580.
  • Mao, Z.; Xiong, J.; Wang, P.; An, J.; Zhang, F.; Liu, Z.; Seung Kim, J. Activity-Based Fluorescence Probes for Pathophysiological Peroxynitrite Fluxes. Coordin. Chem. Rev. 2022, 454, 214356. DOI: 10.1016/j.ccr.2021.214356.
  • Szliszka, E.; Czuba, Z. P.; Domino, M.; Mazur, B.; Zydowicz, G.; Krol, W. Ethanolic Extract of Propolis (EEP) Enhances the Apoptosis- Inducing Potential of TRAIL in Cancer Cells. Molecules. 2009, 14, 738–754. DOI: 10.3390/molecules14020738.
  • Zhu, Y.; Pan, H.; Song, Y.; Jing, C.; Gan, J.-A.; Zhang, J. Mitochondria-Targeted Fluorescent Probe for Rapid Detection of Thiols and Its Application in Bioimaging. Dyes Pigm. 2021, 191, 109376. DOI: 10.1016/j.dyepig.2021.109376.
  • Wang, Y.; Wang, L.; Jiang, E.; Zhu, M.; Wang, Z.; Fan, S.; Gao, Q.; Liu, S.; Li, Q. X.; Hua, R. A Colorimetric and Ratiometric Dual-Site Fluorescent Probe with 2,4-Dinitrobenzenesulfonyl and Aldehyde Groups for Imaging of Aminothiols in Living Cells and Zebrafish. Dyes Pigm. 2018, 156, 338–347. DOI: 10.1016/j.dyepig.2018.04.027.
  • Wang, J.; Zhang, F.; Yang, L.; Wang, B.; Song, X. A Red-Emitting Fluorescent Probe for Sensing and Imaging Biothiols in Living Cells. J. Lumin. 2021, 234, 117994. DOI: 10.1016/j.jlumin.2021.117994.
  • Zhang, S.; Xia, Q.; Wang, F.; Wang, T.; Jia, X.; Yuan, Y.; Zhang, M.; Chen, G. A Fluorescent Probe for Detection Homocysteine in Green and NIR, and Cysteine/Glutathione in NIR Regions. Tetrahedron Lett. 2021, 87, 153157. DOI: 10.1016/j.tetlet.2021.153157.
  • Li, Y.; Zhang, G.; Ma, C.; Chen, F.; Dong, J.; Ge, Y. A Simple Dual-Channel Imidazo[1,5-a]Pyridine-Based Fluorescent Probe for the Discrimination between Cys/Hcy and GSH. Dyes Pigm. 2021, 191, 109381. DOI: 10.1016/j.dyepig.2021.109381.
  • Xu, J.; Pan, J.; Zhang, Y.; Liu, J.; Zeng, L.; Liu, X. Ultrasensitive near-Infrared Fluorescence-Enhanced Probe for Discriminative Detection of GSH and Cys from Different Emission Channels. Sens. Actuators B. 2017, 238, 58–65. DOI: 10.1016/j.snb.2016.07.038.
  • Sun, Y. H.; Han, H. H.; Huang, J. M.; Li, J.; Zang, Y.; Wang, C. Y. A Long-Wavelength Fluorescent Probe with a Large Stokes Shift for Lysosome-Targeted Imaging of Cys and GSH. Spectrochim. Acta A. 2021, 261, 120055. DOI: 10.1016/j.saa.2021.120055.
  • Lu, X.; Wu, M.; Wang, S.; Qin, J.; Li, P. Development of a NIR Fluorescent Probe for the Detection of Intracellular Cysteine and Glutathione and the Monitoring of the Drug Resistance. Talanta. 2021, 235, 122771. DOI: 10.1016/j.talanta.2021.122771.
  • Qi, X.; Shang, L.; Liang, S.; Li, H.; Chen, J.; Xin, C.; Zhao, J.; Deng, M.; Wang, Q.; He, Q.; et al. Development and Applications of a Coumarin-Based “Turn-on” Fluorescent Probe for Effectively Discriminating Reduced Glutathione from Homocysteine and Cysteine in Living Cells and Organisms. Dyes Pigm. 2021, 194, 109625. DOI: 10.1016/j.dyepig.2021.109625.
  • Kolińska, J.; Grzelakowska, A. Novel Styrylbenzimidazolium-Based Fluorescent Probe for Reactive Sulfur Species: Selectively Distinguishing between Bisulfite and Thiol Amino Acids. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 262, 120151., DOI: 10.1016/j.saa.2021.120151.
  • Zhang, K.; Dai, Y.; Li, Q.; Su, Y.; Lv, Y. Unimolecular Chemo-Fluoro-Luminescent Probe for Simultaneous Detection and Imaging of Peroxynitrite and Hypochlorite in Vitro and in Vivo. Sens. Actuators B. 2021, 347, 130609. DOI: 10.1016/j.snb.2021.130609.
  • Yang, X.; Ding, Y.; Li, Y.; Yan, M.; Cui, Y.; Sun, G. Dual-Channel Colorimetric Fluorescent Probe for Determination of Hydrazine and Mercury Ion. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 258, 119868. DOI: 10.1016/j.saa.2021.119868.
  • Wang, X.; Zhou, Y.; Xu, C.; Song, H.; Pang, X.; Liu, X. A Dual-Responsive Fluorescent Probe for Detection of Fluoride Ion and Hydrazine Based on Test Strips. Spectrochim Acta A Mol Biomol Spectrosc. 2019, 211, 125–131. DOI: 10.1016/j.saa.2018.12.004.
  • Zeng, L.; Zeng, H.; Jiang, L.; Wang, S.; Hou, J.; Yoon, J. A Single Fluorescent Chemosensor for Simultaneous Discriminative Detection of Gaseous Phosgene and a Nerve Agent Mimic. Anal. Chem. 2019, 91, 12070–12076. DOI: 10.1021/acs.analchem.9b03230.
  • Zeng, L.; Chen, T.; Zhu, B.; Koo, S.; Tang, Y.; Lin, W.; James, T. D.; Kim, J. S. A Molecular Recognition Platform for the Simultaneous Sensing of Diverse Chemical Weapons. Chem. Sci. 2022, 13, 4523–4532. DOI: 10.1039/D2SC00299J.
  • Wang, Y.; Yue, Y.; Huo, F.; Ma, K.; Yin, C. Substitution-Rearrangement-Cyclization Strategy to Construct Fluorescent Probe for Multicolor Discriminative Analysis Biothiols in Cells and Zebrafish. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 261, 120026. DOI: 10.1016/j.saa.2021.120026.
  • Yue, X.; Chen, J.; Chen, W.; Wang, B.; Zhang, H.; Song, X. An Endoplasmic Reticulum-Targeting Fluorescent Probe for Discriminatory Detection of Cys, Hcy and GSH in Living Cells. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 250, 119347. DOI: 10.1016/j.saa.2020.119347.
  • Yin, G.; Gan, Y.; Jiang, H.; Yu, T.; Liu, M.; Zhang, Y.; Li, H.; Yin, P.; Yao, S. Direct Quantification and Visualization of Homocysteine, Cysteine, and Glutathione in Alzheimer’s and Parkinson’s Disease Model Tissues. Anal Chem. 2021, 93, 9878–9886. DOI: 10.1021/acs.analchem.1c01945.
  • Rong, Y.; Niu, P.; Liu, X.; Chen, W.; Wei, L.; Song, X. Double-Channel Based Fluorescent Probe for Differentiating GSH and H2Sn (n > 1) via a Single-Wavelength Excitation with Long-Wavelength Emission. Sens. Actuators B. 2021, 344, 130224. DOI: 10.1016/j.snb.2021.130224.
  • Niu, P.; Rong, Y.; Wang, Y.; Ni, H.; Zhu, M.; Chen, W.; Liu, X.; Wei, L.; Song, X. A Bifunctional Fluorescent Probe for Simultaneous Detection of GSH and H2Sn (n>1) from Different Channels with Long-Wavelength Emission. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 257, 119789. DOI: 10.1016/j.saa.2021.119789.
  • Zhang, Y.; Zhang, Y.; Yue, Y.; Chao, J.; Huo, F.; Yin, C. A Special o-Dialdehyde Fluorescent Probe Simultaneously Sensing Hcy, GSH and Its Application in Living Cells and Zebrafish Imaging. Chinese Chem. Lett. 2021, 32, 2873–2876. DOI: 10.1016/j.cclet.2021.05.016.
  • Yang, X.; Liu, J.; Xie, P.; Han, X.; Zhang, D.; Ye, Y.; Zhao, Y. Visualization of Biothiols and HClO in Cancer Therapy via a Multi-Responsive Fluorescent Probe. Sens. Actuators B. 2021, 347, 130620. DOI: 10.1016/j.snb.2021.130620.
  • Zheng, Y.-L.; Chai, Z.-H.; Tang, W.; Yan, S.; Dai, F.; Zhou, B. A multi-signal mitochondria-targetable fluorescent probe for simultaneously discriminating Cys/Hcy/H2S, GSH, and SO2 and visualizing the endogenous generation of SO2 in living cells. Sens. Actuators B. 2021, 330, 129343.
  • Li, S.; Huo, F.; Yue, Y.; Ma, K.; Wen, Y.; Yin, C. Distinguishable Multi-Substance Detection Based on Three-Channel NIR Fluorescent Probe in Physiology and Pathology of Living Cells and Zebrafish. Chinese Chem. Lett. 2021, 32, 3870–3875. DOI: 10.1016/j.cclet.2021.05.026.
  • Han, S.; Zhang, H.; Yue, X.; Wang, J.; Yang, L.; Wang, B.; Song, X. A Ratiometric, Fast-Responsive, and Single-Wavelength Excited Fluorescent Probe for the Discrimination of Cys and Hcy. Anal Chem. 2021, 93, 10934–10939. DOI: 10.1021/acs.analchem.1c01750.
  • Yang, Y.; Feng, Y.; Qiu, F.; Iqbal, K.; Wang, Y.; Song, X.; Wang, Y.; Zhang, G.; Liu, W. Dual-Site and Dual-Excitation Fluorescent Probe That Can Be Tuned for Discriminative Detection of Cysteine, Homocystein, and Thiophenols. Anal Chem. 2018, 90, 14048–14055. DOI: 10.1021/acs.analchem.8b04163.
  • Chao, J.; Zhao, J.; Zhang, Y.; Huo, F.; Yin, C. Developing a Dual-Site Fluorescent Probe for Simultaneously Discriminating Cys/Hcy and GSH, and Visualizing Metabolism of Cys to SO2. Sens. Actuators B. 2021, 346, 130569. DOI: 10.1016/j.snb.2021.130569.
  • Guo, X.; Xia, L.; Huang, J.; Wang, Y.; Gu, Y.; Wang, P. Novel Dual-Site Fluorescent Probe for Monitoring Cysteine and Sulfite in Living Cells. RSC Adv. 2018, 8, 21047–21053. DOI: 10.1039/c8ra01683f.
  • Yue, Y.; Huo, F.; Ning, P.; Zhang, Y.; Chao, J.; Meng, X.; Yin, C. Dual-Site Fluorescent Probe for Visualizing the Metabolism of Cys in Living Cells. J Am Chem Soc. 2017, 139, 3181–3185. DOI: 10.1021/jacs.6b12845.
  • Wu, J.; Pan, J.; Ye, Z.; Zeng, L.; Su, D. A Smart Fluorescent Probe for Discriminative Detection of Hydrazine and Bisulfite from Different Emission Channels. Sens. Actuators B. 2018, 274, 274–284. DOI: 10.1016/j.snb.2018.07.161.
  • Wang, H.; Wu, X.; Yang, S.; Tian, H.; Liu, Y.; Sun, B. A Dual-Site Fluorescent Probe for Separate Detection of Hydrogen Sulfide and Bisulfite. Dyes Pigm. 2019, 160, 757–764. DOI: 10.1016/j.dyepig.2018.09.020.
  • Wang, H.; Li, Y.; Yang, S.; Tian, H.; Liu, Y.; Sun, B. A Dual-Function Fluorescent Probe for Discriminative Detection of Hydrogen Sulfide and Hydrazine. J. Photoch. Photobio. A. 2019, 377, 36–42. DOI: 10.1016/j.jphotochem.2019.03.039.
  • Chen, Y.; Lim, J.-Y.; Wu, X. H.; Heo, J. S.; Zhang, J. F.; Yoon, D. W.; Ren, W. X. Development of H2S and HClO Dual-Responsive Fluorescent Probe for Cancer Recognition. Dyes Pigm. 2021, 195, 109666., DOI: 10.1016/j.dyepig.2021.109666.
  • Ren, M.; Xu, Q.; Bai, Y.; Wang, S.; Kong, F. Construction of a Dual-Response Fluorescent Probe for Copper (II) Ions and Hydrogen Sulfide (H2S) Detection in Cells and Its Application in Exploring the Increased Copper-Dependent Cytotoxicity in Present of H2S. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 249, 119299. DOI: 10.1016/j.saa.2020.119299.
  • Ou-Yang, J.; Jiang, W.-L.; Tan, K.-Y.; Liu, H.-W.; Li, S.-J.; Liu, J.; Li, Y.-F.; Li, C.-Y. Two-Photon Fluorescence Probe for Precisely Detecting Endogenous H2S in Lysosome by Employing a Dual Lock System. Sens. Actuators B. 2018, 260, 264–273. DOI: 10.1016/j.snb.2017.12.205.
  • Liu, Y.; Zhang, Y.; Zhang, X. B. Engineering of a Dual-Site Molecular Probe for Logical Bioimaging of Lysosomal H2S and pH. Talanta. 2020, 219, 121286. DOI: 10.1016/j.talanta.2020.121286.
  • Y.; Liu, F.; Meng, L.; He, K.; Liu, W.; Lin, 52. A Dual-Site Two-Photon Fluorescent Probe for Visualizing Lysosomes and Tracking Lysosomal Hydrogen Sulfide with Two Different Sets of Fluorescence Signals in the Living Cells and Mouse Liver Tissues. Chem. Commun. 2016, 52, 7016–7019. DOI: 10.1039/C6CC02368A.
  • Han, Q.; Yang, L.; Song, Y.; Ru, J.; Zhang, H.; Jiang, H.; Wang, X. A Ratiometric Fluorescent Probe for Monitoring the Changes in the Level of Hydrogen Polysulfides in Mitochondria during Stimulus-Induced Redox Imbalance. Dyes Pigm. 2021, 188, 109190. DOI: 10.1016/j.dyepig.2021.109190.
  • Zhang, L.; Liu, H.; Wu, C.; Zheng, Y.; Kai, X.; Xue, Y. A near-Infrared Fluorescent Probe That Can Image Endogenous Hydrogen Polysulfides in Vivo in Tumour-Bearing Mice. Org Biomol Chem. 2021, 19, 911–919. DOI: 10.1039/d0ob02253e.
  • Du, Y.; Wang, B.; Jin, D.; Li, M.; Li, Y.; Yan, X.; Zhou, X.; Chen, L. Dual-Site Fluorescent Probe for Multi-Response Detection of ClO- and H2O2 and Bio-Imaging. Anal Chim Acta. 2020, 1103, 174–182. DOI: 10.1016/j.aca.2019.12.059.
  • Zhang, R.; Zhao, J.; Han, G.; Liu, Z.; Liu, C.; Zhang, C.; Liu, B.; Jiang, C.; Liu, R.; Zhao, T.; et al. Real-Time Discrimination and Versatile Profiling of Spontaneous Reactive Oxygen Species in Living Organisms with a Single Fluorescent Probe. J Am Chem Soc. 2016, 138, 3769–3778. DOI: 10.1021/jacs.5b12848.
  • Song, H.; Zhou, Y.; Xu, C.; Wang, X.; Zhang, J.; Wang, Y.; Liu, X.; Guo, M.; Peng, X. A Dual-Function Fluorescent Probe: Sensitive Detection of Water Content in Commercial Products and Rapid Detection of Hypochlorite with a Large Stokes Shift. Dyes Pigm. 2019, 162, 160–167. DOI: 10.1016/j.dyepig.2018.10.023.
  • Han, J.; Yang, S.; Wang, B.; Song, X. Tackling the Selectivity Dilemma of Benzopyrylium-Coumarin Dyes in Fluorescence Sensing of HClO and SO2. Anal Chem. 2021, 93, 5194–5200. DOI: 10.1021/acs.analchem.0c05266.
  • Wu, L.; Qi, S.; Liu, Y.; Wang, X.; Zhu, L.; Yang, Q.; Du, J.; Xu, H.; Li, Y. A Novel Ratiometric Fluorescent Probe for Differential Detection of HSO3- and ClO- and Application in Cell Imaging and Tumor Recognition. Anal Bioanal Chem. 2021, 413, 1137–1148. DOI: 10.1007/s00216-020-03077-7.
  • Yu, H.; Wu, Y.; Hu, Y.; Gao, X.; Liang, Q.; Xu, J.; Shao, S. Dual-Functional Fluorescent Probe Responds to Hypochlorous Acid and SO2 Derivatives with Different Fluorescence Signals. Talanta. 2017, 165, 625–631. DOI: 10.1016/j.talanta.2017.01.015.
  • Niu, H.; Tang, J.; Zhu, X.; Li, Z.; Zhang, Y.; Ye, Y.; Zhao, Y. A Three-Channel Fluorescent Probe to Image Mitochondrial Stress. Chem Commun (Camb). 2020, 56, 7710–7713. DOI: 10.1039/d0cc02668a.
  • Cheng, W.; Xue, X.; Gan, L.; Jin, P.; Zhang, B.; Guo, M.; Si, J.; Du, H.; Chen, H.; Fang, J. Individual and Successive Detection of H2S and HClO in Living Cells and Zebrafish by a Dual-Channel Fluorescent Probe with Longer Emission Wavelength. Anal Chim Acta. 2021, 1156, 338362., DOI: 10.1016/j.aca.2021.338362.
  • Su, J.; Zhang, S.; Wang, C.; Li, M.; Wang, J.; Su, F.; Wang, Z. MACA Fast and Efficient Method for Detecting H2O2 by a Dual-Locked Model Chemosensor. ACS Omega. 2021, 6, 14819–14823. DOI: 10.1021/acsomega.1c00384.
  • Bi, X.; Wang, Y.; Wang, D.; Liu, L.; Zhu, W.; Zhang, J.; Zha, X. A Mitochondrial-Targetable Dual Functional near-Infrared Fluorescent Probe to Monitor pH and H2O2 in Living Cells and Mice. RSC Adv. 2020, 10, 26874–26879. DOI: 10.1039/d0ra03905e.
  • Zhou, R.; Niu, L.; Hu, Y.; Qi, Q.; Huang, W.; Yang, L. A Novel Dual-Function Fluorescent Probe for the Rapid Detection of Bisulfite and Hydrogen Peroxide in Aqueous Solution and Living Cells. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 248, 119226. DOI: 10.1016/j.saa.2020.119226.
  • Wu, Z.; Liu, M.; Liu, Z.; Tian, Y. Real-Time Imaging and Simultaneous Quantification of Mitochondrial H2O2 and ATP in Neurons with a Single Two-Photon Fluorescence-Lifetime-Based Probe. J Am Chem Soc. 2020, 142, 7532–7541. DOI: 10.1021/jacs.0c00771.
  • Wu, L.; Liu, J.; Tian, X.; Groleau, R. R.; Feng, B.; Yang, Y.; Sedgwick, A. C.; Han, H. H.; Wang, Y.; Wang, H. M.; et al. Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5'-Triphosphate in Cellular Applications. J Am Chem Soc. 2022, 144, 174–183. DOI: 10.1021/jacs.1c07954.
  • Wang, C.; Shu, W.; Chen, Q.; Yang, C.; Su, S.; Gao, M.; Zhang, R.; Jing, J.; Zhang, X. A Simple Dual-Response Fluorescent Probe for Imaging of Viscosity and ONOO- through Different Fluorescence Signals in Living Cells and Zebrafish. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 260, 119990. DOI: 10.1016/j.saa.2021.119990.
  • Li, H.; Liu, Y.; Li, X.; Li, X.; Ma, H. Design, Synthesis and Application of a Dual-Functional Fluorescent Probe for Reactive Oxygen Species and Viscosity. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 246, 119059. DOI: 10.1016/j.saa.2020.119059.
  • Ren, M.; Deng, B.; Zhou, K.; Kong, X.; Wang, J. Y.; Lin, W. Single Fluorescent Probe for Dual-Imaging Viscosity and H2O2 in Mitochondria with Different Fluorescence Signals in Living Cells. Anal Chem. 2017, 89, 552–555. DOI: 10.1021/acs.analchem.6b04385.
  • Fan, L.; Zan, Q.; Wang, X.; Wang, S.; Zhang, Y.; Dong, W.; Shuang, S.; Dong, C. A Mitochondria-Specific Orange/ near-Infrared-Emissive Fluorescent Probe for Dual-Imaging of Viscosity and H2O2 in Inflammation and Tumor Models. Chin. J. Chem. 2021, 39, 1303–1309. DOI: 10.1002/cjoc.202000725.
  • Yan, F.; Sun, X.; Jiang, Y.; Wang, R.; Zhang, Y.; Cui, Y. Dual-Function Fluorescent Probe with Red Emission for Sensing Viscosity and OCl − and Its Applications in Bioimaging. Dyes Pigm. 2020, 182, 108531. DOI: 10.1016/j.dyepig.2020.108531.
  • Fang, Z.; Su, Z.; Qin, W.; Li, H.; Fang, B.; Du, W.; Wu, Q.; Peng, B.; Li, P.; Yu, H.; et al. Two-Photon Dual-Channel Fluorogenic Probe for in Situ Imaging the Mitochondrial H2S/Viscosity in the Brain of Drosophila Parkinson’s Disease Model. Chinese Chem. Lett. 2020, 31, 2903–2908. DOI: 10.1016/j.cclet.2020.03.063.
  • Zhang, X.; Yan, H.; Huo, F.; Chao, J.; Yin, C. Dual-Emission NIR Fluorescent Probe Sensitive Response Biological Microenvironment and Sulfur Dioxide. Sens. Actuators B. 2021, 344, 130244. DOI: 10.1016/j.snb.2021.130244.
  • Qi, Y.-L.; Wang, H.-R.; Kang, Q.-J.; Chen, L.-L.; Qi, P.-F.; He, Z.-X.; Yang, Y.-S.; Zhu, H.-L. A Versatile Fluorescent Probe for Simultaneously Detecting Viscosity, Polarity and Nitroreductases and Its Application in Bioimaging. Sens. Actuators B. 2022, 352, 130989. DOI: 10.1016/j.snb.2021.130989.
  • Qi, Y. L.; Wang, H. R.; Chen, L. L.; Yang, B.; Yang, Y. S.; He, Z. X.; Zhu, H. L. Multifunctional Fluorescent Probe for Simultaneously Detecting Microviscosity, Micropolarity, and Carboxylesterases and Its Application in Bioimaging. Anal Chem. 2022, 94, 4594–4601. DOI: 10.1021/acs.analchem.1c04286.
  • Chen, J.; Wang, N.; Tong, H.; Song, C.; Ma, H.; Zhang, Y.; Gao, F.; Xu, H.; Wang, W.; Lou, K. A Compact Fluorescence/Circular Dichroism Dual-Modality Probe for Detection, Differentiation, and Detoxification of Multiple Heavy Metal Ions via Bond-Cleavage Cascade Reactions. Chinese Chem. Lett. 2021, 32, 3876–3881. DOI: 10.1016/j.cclet.2021.05.047.
  • Zong, L.; Wang, C.; Song, Y.; Xie, Y.; Zhang, P.; Peng, Q.; Li, Q.; Li, Z. A Dual-Function Probe Based on Naphthalene Diimide for Fluorescent Recognition of Hg2+ and Colorimetric Detection of Cu2+. Sens. Actuators B. 2017, 252, 1105–1111. DOI: 10.1016/j.snb.2017.07.124.
  • Wu, X.; Duan, N.; Li, Y.; Yang, S.; Tian, H.; Sun, B. A Dual-Mode Fluorescent Probe for the Separate Detection of Mercury(II) and Hydrogen Sulfide. J. Photoch. Photobio. A. 2020, 388, 112209. DOI: 10.1016/j.jphotochem.2019.112209.
  • Wu, X.; Li, Y.; Yang, S.; Tian, H.; Sun, B. Discriminative Detection of Mercury (II) and Hydrazine Using a Dual-Function Fluorescent Probe. Luminescence. 2020, 35, 754–762. DOI: 10.1002/bio.3781.
  • Liu, J.; Li, J.; Tang, J.; Yang, X.; Zhang, D.; Ye, Y.; Zhao, Y. Mitochondria-Targeted NIR Fluorescent Probe for Sensing Hg2+/HSO3- and Its Intracellular Applications. Talanta. 2021, 234, 122606. DOI: 10.1016/j.talanta.2021.122606.
  • Xie, Z.; Yin, B.; Shen, J.; Hong, D.; Zhu, L.; Ge, J.; Zhu, Q. A Dual Functional Fluorogenic Probe for Visualization of Intracellular pH and Formaldehyde with Distinct Fluorescence Signals. Org. Biomol. Chem. 2018, 16, 4628–4632. DOI: 10.1039/C8OB00989A.
  • Xie, Z.; Zhou, Y.; Fu, M.; Ni, L.; Tong, Y.; Yu, Y.; Li, N.; Yang, Z.; Zhu, Q.; Wang, J. A 1,8-Naphthalimide-Based Lysosome-Targeting Dual-Analyte Fluorescent Probe for the Detection of pH and Palladium in Biological Samples. Talanta. 2021, 231, 122365. DOI: 10.1016/j.talanta.2021.122365.
  • Muthusamy, S.; Rajalakshmi, K.; Zhu, D.; Zhu, W.; Wang, S.; Lee, K.-B.; Xu, H.; Zhao, L. Dual Detection of Mercury (II) and Lead (II) Ions Using a Facile Coumarin-Based Fluorescent Probe via Excited State Intramolecular Proton Transfer and Photo-Induced Electron Transfer Processes. Sens. Actuators B. 2021, 346, 130534. DOI: 10.1016/j.snb.2021.130534.
  • Erdemir, S. Fluorometric Dual Sensing of Hg2+ and Al3+ by Novel Triphenylamine Appended Rhodamine Derivative in Aqueous Media. Sens. Actuators B. 2019, 290, 558–564. DOI: 10.1016/j.snb.2019.04.037.
  • Dong, M.; Tang, J.; Lv, Y.; Liu, Y.; Wang, J.; Wang, T.; Bian, J.; Li, C. A Dual-Function Fluorescent Probe for Hg (II) and Cu (II) Ions with Two Mutually Independent Sensing Pathways and Its Logic Gate Behavior. Spectrochim Acta A Mol Biomol Spectrosc. 2020, 226, 117645. DOI: 10.1016/j.saa.2019.117645.
  • Dong, Z.; Chen, W.; Li, H.; Dai, Y.; Zheng, T.; Zhang, H.; Xu, H.; Lu, H. A Dual-Functional Colorimetric and “on-off” Fluorescent Probe Based on Purine Derivative for Detecting Pd2+ and Cu2+: Application as Test Strips. Inorg. Chem. Commun. 2020, 116, 107915. DOI: 10.1016/j.inoche.2020.107915.
  • Hu, T.; Wang, L.; Li, J.; Zhao, Y.; Cheng, J.; Li, W.; Chang, Z.; Sun, C. A New Fluorescent Sensor L Based on Fluorene-Naphthalene Schiff Base for Recognition of Al3+ and Cr3+. Inorg. Chim. Acta. 2021, 524, 120421. DOI: 10.1016/j.ica.2021.120421.
  • Velmurugan, K.; Prabhu, J.; Raman, A.; Duraipandy, N.; Kiran, M. S.; Easwaramoorthi, S.; Tang, L.; Nandhakumar, R. Dual Functional Fluorescent Chemosensor for Discriminative Detection of Ni 2+ and Al 3+ Ions and Its Imaging in Living Cells. ACS Sustainable Chem. Eng. 2018, 6, 16532–16543. DOI: 10.1021/acssuschemeng.8b03625.
  • Zheng, Q.; Ding, F.; Hu, X.; Feng, J.; Shen, J.; He, X. ESIPT-Based Fluorescent Probe for Bioimaging and Identification of Group IIIA Ions in Live Cells and Zebrafish. Bioorg Chem. 2021, 109, 104746. DOI: 10.1016/j.bioorg.2021.104746.
  • Roy, N.; Nath, S.; Dutta, A.; Mondal, P.; Paul, P. C.; Singh, T. S. A Highly Efficient and Selective Coumarin Based Fluorescent Probe for Colorimetric Detection of Fe3+ and Fluorescence Dual Sensing of Zn2+ and Cu2+. RSC Adv. 2016, 6, 63837–63847. DOI: 10.1039/C6RA12217E.
  • Anbu, S.; Paul, A.; Surendranath, K.; Solaiman, N. S.; Pombeiro, A. J. L. A Benzimidazole-Based New Fluorogenic Differential/Sequential Chemosensor for Cu2+, Zn2+, CN-, P2O74-, DNA, Its Live-Cell Imaging and Pyrosequencing Applications. Sens. and Actuators B. 2021, 337, 129785. DOI: 10.1016/j.snb.2021.129785.
  • Zhang, B.; Liu, H.; Wu, F.; Hao, G.; Chen, Y.; Tan, C.; Tan, Y.; Jiang, Y. A Dual-Response Quinoline-Based Fluorescent Sensor for the Detection of Copper (II) and Iron(III) Ions in Aqueous Medium. Sens. Actuators B. 2017, 243, 765–774. DOI: 10.1016/j.snb.2016.12.067.
  • Dalapati, S.; Jana, S.; Alam, M. A.; Guchhait, N. Multifunctional Fluorescent Probe Selective for Cu(II) and Fe(III) with Dual-Mode of Binding Approach. Sens. Actuators B. 2011, 160, 1106–1111. DOI: 10.1016/j.snb.2011.09.034.
  • Shanmugapriya, R.; Saravana Kumar, P.; Poongodi, K.; Nandhini, C.; Elango, K. P. Optical Detection of Al(III) and Cu(II) Ions in an Aqueous Medium by Using a Simple Probe Possessing O,O-Donor Moiety. Phosphorus. Sulfur. 2021, 196, 780–790. DOI: 10.1080/10426507.2021.1920940.
  • Xie, X.; Qin, Y. A Dual Functional near Infrared Fluorescent Probe Based on the Bodipy Fluorophores for Selective Detection of Copper and Aluminum Ions. Sens. Actuators B. 2011, 156, 213–217. DOI: 10.1016/j.snb.2011.04.020.
  • Duan, N.; Feng, J.; Deng, B.; Yang, S.; Tian, H.; Sun, B. A Colourimetric Fluorescent Probe for the Sensitive Detection of Total Iron in Wine. Food Chem. 2022, 383, 132594. DOI: 10.1016/j.foodchem.2022.132594.
  • Zhang, Y.-P.; Niu, W.-Y.; Ma, C.-M.; Yang, Y.-S.; Guo, H.-C.; Xue, J.-J. Fluorogenic Recognition of Zn2+, Cd2+ by a New Pyrazoline-Based Multi-Analyte Chemosensor and Its Application in Live Cell Imaging. Inorg. Chem. Commun. 2021, 130, 108735. DOI: 10.1016/j.inoche.2021.108735.
  • Mikata, Y.; Takekoshi, A.; Kaneda, M.; Yonemura, S.; Aono, Y.; Matsumoto, A.; Konno, H.; Burdette, S. C. N,N,N′,N′-Tetrakis(3-Isoquinolylmethyl)-.2,6-Lutidylenediamine (3-isoTQLN): a Fluorescent Zn 2+ /Cd 2+ Dual Sensor as a Hybrid of 2-Quinolyl/1-Isoquionolyl Counterparts TQLN/1-isoTQLN. Eur. J. Inorg. Chem. 2021, 2021, 1287–1296. DOI: 10.1002/ejic.202001171.
  • Qiu, S.; Yu, J.; Zhou, T.; Zhang, K.; Duan, Y.; Ban, X.; Zhu, Q.; Shi, L.; Zhang, D. Thermally Activated Delayed Fluorescence Fluorescent Probe Based on Triazine as Emission Core for Metal Ions Detection. Opt. Mater. 2021, 119, 111303. DOI: 10.1016/j.optmat.2021.111303.
  • Yang, X.; Liu, X.; Li, Y.; Wu, F.; Mao, J.; Yuan, Y.; Cui, Y.; Sun, G.; Zhang, G. A Differentially Selective Probe Based on Diketopyrrolopyrrole with Fluorescence Turn-on Response to Fe(3+), and Dual-Mode Turn-on and Ratiometric Response to Au(3+), and Its Application in Living Cell Imaging. Biosens Bioelectron. 2016, 80, 288–293. DOI: 10.1016/j.bios.2016.01.085.
  • Sun, J.; Li, T-r.; Yang, Z-y A Novel Fluorescent Probe Based on 7,8-Benzochromone-3-Carbaldehyde-(Rhodamine B Carbonyl) Hydrazone for Detection of Trivalent Cations and Zn2+ in Different Systems. J. Photoch. Photobio. A. 2021, 411, 113207. DOI: 10.1016/j.jphotochem.2021.113207.
  • Sun, X. J.; Liu, T. T.; Li, N. N.; Zeng, S.; Xing, Z. Y. A Novel Dual-Function Probe for Recognition of Zn2+ and Al3+ and Its Application in Real Samples. Spectrochim Acta A Mol Biomol Spectrosc. 2020, 228, 117786. DOI: 10.1016/j.saa.2019.117786.
  • Wang, Y.; Wang, Z. G.; Song, X. Q.; Chen, Q.; Tian, H.; Xie, C. Z.; Li, Q. Z.; Xu, J. Y. A Dual Functional Turn-on Non-Toxic Chemosensor for Highly Selective and Sensitive Visual Detection of Mg2+ and Zn2+: the Solvent-Controlled Recognition Effect and Bio-Imaging Application. Analyst. 2019, 144, 4024–4032. DOI: 10.1039/c9an00583h.
  • Li, M.; Ruan, S.; Yang, H.; Zhang, Y.; Yang, Y.; Song, J.; Xu, X.; Wang, Z.; Wang, S. Nopinone-Based AIE-Active Dual-Functional Fluorescent Chemosensor for Hg2+ and Cu2+ and Its Environmental and Biological Applications. Dalton Trans. 2020, 49, 15299–15309. DOI: 10.1039/d0dt02888f.
  • Tang, Y.; Li, Y.; Han, J.; Mao, Y.; Ni, L.; Wang, Y. A Coumarin Based Fluorescent Probe for Rapidly Distinguishing of Hypochlorite and Copper (II) Ion in Organisms. Spectrochim Acta A Mol Biomol Spectrosc. 2019, 208, 299–308. DOI: 10.1016/j.saa.2018.10.019.
  • Yin, J.; Wang, Z.; Zhao, F.; Yang, H.; Li, M.; Yang, Y. A Novel Dual Functional Pyrene-Based Turn-on Fluorescent Probe for Hypochlorite and Copper (II) Ion Detection and Bioimaging Applications. Spectrochim Acta A Mol Biomol Spectrosc. 2020, 239, 118470. DOI: 10.1016/j.saa.2020.118470.
  • Ruan, S.; Wu, S.; Yang, L.; Li, M.; Zhang, Y.; Wang, Z.; Wang, S. A Novel Turn-on Fluorescent Probe Based on Berberine for Detecting Hg2+ and ClO − with the Different Fluorescence Signals. Microchem. J. 2021, 166, 106199. DOI: 10.1016/j.microc.2021.106199.
  • Zhang, D.; Qi, Y.; Li, Y.; Song, Y.; Xian, C.; Li, H.; Cong, P. A New Spiropyran-Based Fluorescent Probe for Dual Sensing of Ferrous Ion and pH. J Fluoresc. 2021, 31, 1133–1141. DOI: 10.1007/s10895-021-02741-0.
  • Aysha, T. S.; El-Sedik, M. S.; Mohamed, M. B. I.; Gaballah, S. T.; Kamel, M. M. Historical formulations of lake pigments and dyes derived from lac: A study of compositional variability. Dyes Pigm. 2019, 170, 107579.
  • Nouri Moghadam, F.; Amirnasr, M.; Meghdadi, S.; Eskandari, K.; Buchholz, A.; Plass, W. A New Fluorene Derived Schiff-Base as a Dual Selective Fluorescent Probe for Cu2+ and CN. Spectrochim Acta A Mol Biomol Spectrosc. 2019, 207, 6–15. DOI: 10.1016/j.saa.2018.08.058.
  • Wang, Q.; Zheng, D.; Cao, Q.; Huang, K.; Qin, D. A Dual-Response Fluoran-Phenothiazine Hybrid Fluorescent Probe for Selective Sensing of Fe3+ and ClO- and Cell Imaging Application. Spectrochim Acta A Mol Biomol Spectrosc. 2021, 261, 120061. DOI: 10.1016/j.saa.2021.120061.
  • Feng, H.; Liu, J.; Qaitoon, A.; Meng, Q.; Sultanbawa, Y.; Zhang, Z.; Xu, Z. P.; Zhang, R. Responsive Small-Molecule Luminescence Probes for Sulfite/Bisulfite Detection in Food Samples. TrAC Trend Anal. Chem. 2021, 136, 116199., DOI: 10.1016/j.trac.2021.116199.
  • Zhou, F.; Sultanbawa, Y.; Feng, H.; Wang, Y.; Meng, Q.; Wang, Y.; Zhang, Z.; Zhang, R. A New Red-Emitting Fluorescence Probe for Rapid and Effective Visualization of Bisulfite in Food Samples and Live Animals. J Agric Food Chem. 2019, 67, 4375–4383. DOI: 10.1021/acs.jafc.8b07110.
  • Zhou, F.; Feng, H.; Li, H.; Wang, Y.; Zhang, Z.; Kang, W.; Jia, H.; Yang, X.; Meng, Q.; Zhang, R. Red-Emission Probe for Ratiometric Fluorescent Detection of Bisulfite and Its Application in Live Animals and Food Samples. ACS Omega. 2020, 5, 5452–5459. DOI: 10.1021/acsomega.0c00063.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.