60
Views
0
CrossRef citations to date
0
Altmetric
Review Article

Malondialdehyde Analysis in Biological Samples by Capillary Electrophoresis: The State of Art

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon

References

  • Ayala, A.; Muñoz, M. F.; Argüelles, S. Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal. Oxid. Med. Cell Longev. 2014, 2014, 360438–360431. DOI: 10.1155/2014/360438.
  • Yin, H.; Xu, L.; Porter, N. A. Free Radical Lipid Peroxidation: Mechanisms and Analysis. Chem. Rev. 2011, 111, 5944–5972. DOI: 10.1021/cr200084z.
  • Mas-Bargues, C.; Escrivá, C.; Dromant, M.; Borrás, C.; Viña, J. Lipid Peroxidation as Measured by Chromatographic Determination of Malondialdehyde. Human Plasma Reference Values in Health and Disease. Arch Biochem Biophys 2021, 709, 108941. DOI: 10.1016/j.abb.2021.108941.
  • Del Rio, D.; Stewart, A. J.; Pellegrini, N. A Review of Recent Studies on Malondialdehyde as Toxic Molecule and Biological Marker of Oxidative Stress. Nutrition, Metabolism and Cardiovascular Diseases 2005, 316–328. DOI: 10.1016/j.numecd.2005.05.003.
  • Grotto, D.; Maria, L. S.; Valentini, J.; Paniz, C.; Schmitt, G.; Garcia, S. C.; Pomblum, V. J.; Rocha, J. B. T.; Farina, M. Importance of the Lipid Peroxidation Biomarkers and Methodological Aspects for Malondialdehyde Quantification. Quím. Nova 2009, 32, 169–174. DOI: 10.1590/S0100-40422009000100032.
  • Tsikas, D. Assessment of Lipid Peroxidation by Measuring Malondialdehyde (MDA) and Relatives in Biological Samples: Analytical and Biological Challenges. Anal. Biochem. 2017, 524, 13–30. DOI: 10.1016/j.ab.2016.10.021.
  • Zinellu, A.; Sotgia, S.; Deiana, L.; Carru, C. Field-Amplified Sample Injection Combined with Pressure-Assisted Capillary Electrophoresis UV Detection for the Simultaneous Analysis of Allantoin, Uric Acid, and Malondialdehyde in Human Plasma. Anal. Bioanal. Chem. 2011, 399, 2855–2861. DOI: 10.1007/s00216-010-4648-x.
  • Georgakopoulos, C. D.; Lamari, F. N.; Karathanasopoulou, IN.; Gartaganis, V. S.; Pharmakakis, N. M.; Karamanos, N. K. Tear Analysis of Ascorbic Acid, Uric Acid and Malondialdehyde with Capillary Electrophoresis. Biomed. Chromatogr. 2010, 24, 852–857. DOI: 10.1002/bmc.1376.
  • Korizis, K. N.; Exarchou, A.; Michalopoulos, E.; Georgakopoulos, C. D.; Kolonitsiou, F.; Mantagos, S.; Gartaganis, S. P.; Karamanos, N. K. Determination of Malondialdehyde by Capillary Electrophoresis, Application to Human Plasma and Relation of Its Levels with Prematurity. Biomed. Chromatogr. 2001, 15, 287–291. DOI: 10.1002/bmc.78.
  • Huang, Y.; Chen, H.; Liu, Q.; Hu, J.; Hu, D.; Huang, Z.; Xu, Z.; Wan, R. Obesity Difference on Association Blood Malondialdehyde Level and Diastolic Hypertension in the Elderly Population: A Cross-Sectional Analysis. Eur. J. Med. Res. 2023, 28, 44. DOI: 10.1186/s40001-022-00983-7.
  • Toto, A.; Wild, P.; Graille, M.; Turcu, V.; Crézé, C.; Hemmendinger, M.; Sauvain, J. J.; Bergamaschi, E.; Canu, I. G.; Hopf, N. B. Urinary Malondialdehyde (MDA) Concentrations in the General Population—A Systematic Literature Review and Meta-Analysis. Toxics 2022, 10, 160. DOI: 10.3390/toxics10040160.
  • Ma, L.; He, Q.; Qiu, Y.; Liu, H.; Wu, J.; Liu, G.; Brennan, C.; Brennan, M. A.; Zhu, L. Food Matrixes Play a Key Role in the Distribution of Contaminants of Lipid Origin: A Case Study of Malondialdehyde Formation in Vegetable Oils during Deep-Frying. Food Chem. 2021, 347, 129080. DOI: 10.1016/j.foodchem.2021.129080.
  • Custodio-Mendoza, J. A.; Valente, I. M.; Ramos, R. M.; Lorenzo, R. A.; Carro, A. M.; Rodrigues, J. A. Analysis of Free Malondialdehyde in Edible Oils Using Gas-Diffusion Microextraction. J. Food Compos. Anal. 2019, 82, 103254. DOI: 10.1016/j.jfca.2019.103254.
  • Papastergiadis, A.; Mubiru, E.; Van Langenhove, H.; De Meulenaer, B. Malondialdehyde Measurement in Oxidized Foods: Evaluation of the Spectrophotometric Thiobarbituric Acid Reactive Substances (TBARS) Test in Various Foods. J. Agric. Food Chem. 2012, 60, 9589–9594. DOI: 10.1021/jf302451c.
  • Giera, M.; Lingeman, H.; Niessen, W. M. A. Recent Advancements in the LC- and GC-Based Analysis of Malondialdehyde (MDA): A Brief Overview. Chromatographia 2012, 75, 433–440. DOI: 10.1007/s10337-012-2237-1.
  • Biondi, R.; Brancorsini, S.; Egidi, M. G.; Poli, G.; Capodicasa, E.; Tritto, I.; Carlo, G.; Di Renzo, G. C.; Duica, F.; Cretoiu, D. Free and Total Malondialdehyde Measured as 2, 4-Dinitrophenylhydrazine Adduct by HPLC-UV in Hemodialysis Patient Serum. J. Clin. Chem. Lab. Med. 2019, 2, 1–9.
  • De Vecchi, A. F.; Bamonti, F.; Novembrino, C.; Ippolito, S.; Guerra, L.; Lonati, S.; Salini, S.; Aman, C. S.; Scurati-Manzoni, E.; Cighetti, G. Free and Total Plasma Malondialdehyde in Chronic Renal Insufficiency and in Dialysis Patients. Nephrol. Dial. Transplant. 2009, 24, 2524–2529. DOI: 10.1093/ndt/gfp102.
  • Cui, X.; Gong, J.; Han, H.; He, L.; Teng, Y.; Tetley, T.; Sinharay, R.; Chung, K. F.; Islam, T.; Gilliland, F.; et al. Relationship between Free and Total Malondialdehyde, a Well-Established Marker of Oxidative Stress, in Various Types of Human Biospecimens. J. Thorac. Dis. 2018, 10, 3088–3097. DOI: 10.21037/jtd.2018.05.92.
  • Draper, H. H.; Hadley, M. Malondialdehyde Determination as Index of Lipid Peroxidation. Methods Enzymol. 1990, 186, 421–431. DOI: 10.1016/0076-6879(90)86135-i.
  • Cighetti, G.; Debiasi, S.; Paroni, R.; Allevi, P. Free and Total Malondialdehyde Assessment in Biological Matrices by Gas Chromatography-Mass Spectrometry: What Is Needed for an Accurate Detection. Anal. Biochem. 1999, 266, 222–229. DOI: 10.1006/abio.1998.2952.
  • Jové, M.; Mota-Martorell, N.; Pamplona, R.; Pradas, I.; Martín-Gari, M.; Ayala, V. The Advanced Lipoxidation End-Product Malondialdehyde-Lysine in Aging and Longevity. Antioxidants 2020, 9, 1132. DOI: 10.3390/antiox9111132.
  • Domijan, A. M.; Ralić, J.; Radić Brkanac, S.; Rumora, L.; Žanić-Grubišić, T. Quantification of Malondialdehyde by HPLC-FL - Application to Various Biological Samples. Biomed. Chromatogr. 2015, 29, 41–46. DOI: 10.1002/bmc.3361.
  • Paroni, R.; Fermo, I.; Cighetti, G. Validation of Methyl Malondialdehyde as Internal Standard for Malondialdehyde Detection by Capillary Electrophoresis Q. Anal. Biochem. 2002, 307, 92–98. DOI: 10.1016/s0003-2697(02)00002-7.
  • Claeson, K.; Aberg, F.; Karlberg, B. Free Malondialdehyde Determination in Rat Brain Tissue by Capillary Zone Electrophoresis: Evaluation of Two Protein Removal Procedures. J. Chromatogr. B. Biomed. Sci. Appl. 2000, 740, 87–92. DOI: 10.1016/s0378-4347(00)00030-x.
  • Cooley, J. C.; Lunte, C. E. Detection of Malondialdehyde in Vivo Using Microdialysis Sampling with CE-Fluorescence. Electrophoresis 2011, 32, 2994–2999. DOI: 10.1002/elps.201100143.
  • Grotto, D.; Santa Maria, L. D.; Boeira, S.; Valentini, J.; Charão, M. F.; Moro, A. M.; Nascimento, P. C.; Pomblum, V. J.; Garcia, S. C. Rapid Quantification of Malondialdehyde in Plasma by High Performance Liquid Chromatography-Visible Detection. J. Pharm. Biomed. Anal. 2007, 43, 619–624. DOI: 10.1016/j.jpba.2006.07.030.
  • Antolovich, M.; Prenzler, P. D.; Patsalides, E.; McDonald, S.; Robards, K. Methods for Testing Antioxidant Activity. Analyst R. Soc. Chem. 2002, 127, 183–198. DOI: 10.1039/b009171p.
  • Kartavenka, K.; Panuwet, P.; Yakimavets, V.; Jaikang, C.; Thipubon, K.; D'Souza, P. E.; Barr, D. B.; Ryan, P. B. LC-MS Quantification of Malondialdehyde-Dansylhydrazine Derivatives in Urine and Serum Samples. J. Anal. Toxicol. 2021, 44, 470–481. DOI: 10.1093/JAT/BKZ112.
  • Dong, X.; Tang, J.; Chen, X. Sensitive Determination of Malondialdehyde in Rat Prostate by High Performance Liquid Chromatography with Fluorescence Detection. Sci. Rep. 2020, 10, 3990. DOI: 10.1038/s41598-020-61074-3.
  • Wu, Z.; Wang, Y.; Wang, Y.; Zhang, K.; Lai, Y. Robust and Reliable Detection of Malondialdehyde in Biological Samples via Microprobe-Triggered Surface-Enhanced Raman Spectroscopy. Microchem. J. 2022, 181, 107815. DOI: 10.1016/j.microc.2022.107815.
  • Valenzuela, A. The Biological Significance of Malondialdehyde Determination in the Assessment of Tissue Oxidative Stress. Life Sci. 1991, 48, 301–309. DOI: 10.1016/0024-3205(91)90550-U.
  • Wang, Y.; Yu, C.; Ji, H.; Liu, Z.; Wang, X.; Ji, Y.; Sun, X.; Zhao, Y.; Qiu, X.; Zhang, T.; et al. Label-Free Therapeutic Drug Monitoring in Human Serum by the 3-Step Surface Enhanced Raman Spectroscopy and Multivariate Analysis. Chem. Eng. J. 2023, 452, 139588. DOI: 10.1016/j.cej.2022.139588.
  • Li, X.; Wang, X.; Liu, J.; Dai, M.; Zhang, Q.; Li, Y.; Huang, J. A. Surface-Enhanced Raman Spectroscopy Detection of Organic Molecules and: In Situ Monitoring of Organic Reactions by Ion-Induced Silver Nanoparticle Clusters. Phys. Chem. Chem. Phys. 2022, 24, 2826–2831. DOI: 10.1039/d1cp04857k.
  • Oliveira, M. A.; L. de, Soares, D.; d C.; Tostes, G. S.; Guimarães, M.; d C.; Vaz, F. A. S. Optimization of an Alternative Methodology for Simultaneous Analysis of Nitrite and Nitrate in Water from Urban Stream by Capillary Electrophoresis under Direct UV Detection. AJAC 2012, 03, 484–490. DOI: 10.4236/ajac.2012.37064.
  • Wilson, D. W.; Metz, H. N.; Graver, L. M.; Rao, P. S. Direct Method for Quantification of Free Malondialdehyde with High- Performance Capillary Electrophoresis in Biological Samples. Clin. Chem. 1997, 43, 1982–1984. DOI: 10.1093/clinchem/43.10.1982.
  • Zinellu, A.; Sotgia, S.; Deiana, L.; Carru, C. Field-Amplified Online Sample Stacking Capillary Electrophoresis UV Detection for Plasma Malondialdehyde Measurement. Electrophoresis 2011, 32, 1893–1897. DOI: 10.1002/elps.201100056.
  • Wang, T.; Luo, D.; Chen, Z.; Qu, Y.; Ma, X.; Ye, J.; Chu, Q.; Huang, D. Sensitive Determination of Aldehyde Metabolites in Exhaled Breath Condensate Using Capillary Electrophoresis with Laser-Induced Fluorescence Detection. Anal. Bioanal. Chem. 2018, 410, 7203–7210. DOI: 10.1007/s00216-018-1327-9.
  • Baños, C. E.; Silva, M. A Novel Clean-up Method for Urine Analysis of Low-Molecular Mass Aldehydes by Capillary Electrophoresis with Laser-Induced Fluorescence Detection. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2011, 879, 1412–1418. DOI: 10.1016/j.jchromb.2010.10.033.
  • Claeson, K.; Thorsén, G.; Karlberg, B. Methyl Malondialdehyde as an Internal Standard for the Determination of Malondialdehyde. J. Chromatogr. B Biomed. Sci. Appl. 2001, 751, 315–323. DOI: 10.1016/S0378-4347(00)00490-4.
  • Lačná, J.; Foret, F.; Kubáň, P. Sensitive Determination of Malondialdehyde in Exhaled Breath Condensate and Biological Fluids by Capillary Electrophoresis with Laser Induced Fluorescence Detection. Talanta 2017, 169, 85–90. DOI: 10.1016/j.talanta.2017.03.061.
  • Olsson, J.; Karlberg, B.; Kristensson, K.; Aberg, F. Determination of Malondialdehyde in Rat Brain by Capillary Zone Electrophoresis. J. Chromatogr. B Biomed. Sci. Appl. 1998, 707, 51–57. DOI: 10.1016/s0378-4347(97)00600-2.
  • Nguyen, B. T.; Kang, M. J. Application of Capillary Electrophoresis with Laser-Induced Fluorescence to Immunoassays and Enzyme Assays. Molecules 2019, 24, 1977. DOI: 10.3390/molecules24101977.
  • do Nascimento, M. P.; Marques, R.; Pereira, M. P.; Martins, R. d S.; Irene Bombonato, F.; de Oliveira, M. A. L. Determination of Purity and Anionic Exchange Efficiency of Amino Acid Ionic Liquids Synthesis by Multiple-Injection Capillary Zone Electrophoresis. Talanta 2022, 237, 122945. DOI: 10.1016/j.talanta.2021.122945.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.