Structural relationships of sugars to taste

References

• Theophrastus . 1964 . De Sensibus , Edited by: Stratton , G. M. and Bonset , E. J. Amsterdam : P. Schippers .
   Google Scholar
• Harper , R. 1972 . Human Senses in Action , London : Churchill Livingstone .
   Google Scholar
• Moncrief , R. W. 1946 . The Chemical Senses , New York : John Wiley & Sons .
   Google Scholar
• Reinicke , R. 1943 . The chemical conditions for the taste sensation “sweet,”; . Zuckerindustrie , 1 : 79
   Google Scholar
• Lee , C. K. 1973 . “ The Stereochemistry of Sweetness ” . Weybridge, , England : Reading University . Ph.D. thesis
   Google Scholar
• Cohn , G. 1914 . Organic flavours, (The relation of chemical constitution to taste) . Pharm. Zentralhalle , 55 : 735
   Google Scholar
• Oertly , E. and Myers , R. G. 1919 . A new theory relating constitution to taste. Simple relations between the constitution of aliphatic compounds and their sweet taste . J. Am. Chem. Soc. , 41 : 855
   Google Scholar
• Kodama , S. 1920 . Taste . J. Tokyo Chem. Soc. , 41 : 495
   Google Scholar
• Neri , A. and Grimaldi , G. 1937 . Contribution to the study of the relation between taste and chemical constitution. Research on the naphthoisotriazine group. Note I.V . Gazz. Chim. ltal. , 67 : 273
   Google Scholar
• Tsuzuki , Y. 1947 . Sweetness and the configuration of sugars . Kagaku (Science) , 17 : 342
   Google Scholar
• Kaneko , T. 1938 . Taste and constitution of a‐amino acids . J. Chem. Soc. , 59 : 433
   Google Scholar
• Lawrence , A. R. and Ferguson , L.N. 1959 . Exploratory physicochemical studies on the sense of taste . Nature , 183 : 1469
   Google Scholar
• Deutsch , E. W. and Hansch , C. 1966 . Dependence of relative sweetness on hydrophobic bonding . Nature , 211 : 75
   PubMedGoogle Scholar
• Deutsch , E. W. and Jones , A. D. 1960 . Diluted water: an explanation of the rat's preference for saline . J. Comp. Physiol. Psychol. , 53 : 122
   PubMedGoogle Scholar
• Blanskma , J. J. and Hoegen , D. 1947 . Sweet taste of 4‐nitro‐2‐aminotoluene, 4‐nitro‐2‐amino‐benzoic acid, and 2‐nitro‐4‐aminobenzoic acid . Recl. Trav. Chim. des Pays‐Bas , 66 : 365
   Google Scholar
• Cameron , A. T. 1947 . The Taste Sense and the Relative Sweetness of Sugars , Special Report No. 9 34 New York : Sugar Research Foundation .
   Google Scholar
• Lichtenstein , P. E. 1948 . The relative sweetness of sucrose and dextrose . J. Exp. Physiol. , 38 : 578
   Google Scholar
• Lindley , M. G. 1974 . “ Molecular Structure and Sweet Taste ” . Weybridge, , England : Reading University . Ph.D. thesis
   Google Scholar
• Loginov , N. E. 1941 . A new method for measuring sweetness of sugars . Pishch. Promst. SSSR , 1 : 32
   Google Scholar
• Beck , G. 1943 . Uber raumliche Verhaltnisse bei Kohlenhydraten. Aminosauren u. Kohlenwasserstaffen . Men. Chem. Ztg. , 46 : 18
   Google Scholar
• Baradi , A. E. and Bourne , G. H. 1951 . Localisation of gustatory and olfactory enzymes in the rabbit, and the problems of taste and smell . Nature , 168 : 977
   PubMed Web of Science ®Google Scholar
• Trefz , B. 1972 . Histochemical investigation of the model specificity of taste . J. Dent. Res. , 51 : 1203
   Google Scholar
• Koshtoiants , K. S. and Katalin , R. 1958 . The enzymatic basis of tasting . Biophysics (USSR) , 3 : 652
   Google Scholar
• Tsuzuki , Y. and Yamazaki , J. 1953 . On the sweetness of fructose and other sugars, especially its variation with temperature . Biochem. Z. , 323 : 525
   Google Scholar
• Dethier , V. G. 1956 . “ Chemoreceptor mechanisms ” . In Molecular Structure and Functional Activity of Nerve Cells , Edited by: Grenell , R. G. and Mullins , L. J. Vol. 1 , Arlington, Va. : American Institute of Biological Sciences .
   Google Scholar
• Dethier , V. G. and Arab , Y. M. 1958 . Effect of temperature on the contact chemoreceptors of the blowfly . J. Taiwan Pharm. Assoc. , 2 : 153
   Google Scholar
• Beidler , L. M. 1954 . A theory of taste stimulation . J. Gen. Physiol. , 38 : 133
   PubMed Web of Science ®Google Scholar
• Scatchard , G. 1963 . The attraction of proteins for small molecules and ions . Ann. N. Y. Acad. Sci. , 51 : 660
   Google Scholar
• Evans , D. R. and Mellon , D. Jr. 1962 . Stimulation of a primary taste receptor . J. Gen. Physiol. , 45 : 651
   PubMed Web of Science ®Google Scholar
• Stone , H. and Oliver , S. M. 1969 . Measurement of the relative sweetness of selected sweeteners and sweetener mixtures . J. Food Sci. , 34 : 215
   Web of Science ®Google Scholar
• Dzendolet , E. 1967 . Beidler's taste equation: a correction . Percept. Psychophys. , 2 : 519
   Google Scholar
• Shallenberger , R. S. 1963 . Hydrogen bonding and the varying sweetness of sugars . J. Food Sci. , 28 : 584
   Google Scholar
• Shallenberger , R. S. 1964 . Sweetening agents in foods . Agric. Sci Rev. , 2 : 11
   Google Scholar
• Shallenberger , R. S. 1964 . Why do sugars taste sweet . New Sci , 407 (3) : 569
   Google Scholar
• Shallenberger , R. S. , Acree , T. E. and Guild , W. E. 1965 . Configuration, conformation, and sweetness of hexose anomers . J. Food Sci. , 30 : 560
   Google Scholar
• Shallenberger , R. S. and Acree , T. E. 1971 . “ Chemical structure of compounds and their sweet and bitter taste ” . In Handbook of Sensory Physiology , Edited by: Beidler , L. M. 221 Berlin : Springer‐Verlag .
   Google Scholar
• Shallenberger , R. S. and Acree , T. E. 1967 . Molecular theory of sweet taste. . Nature , 216 : 480
   PubMed Web of Science ®Google Scholar
• Shallenberger , R. S. 1968 . “ Some reactions of free sugars in foods ” . In Frontiers in Food Research , 40 Ithaca : Proc. Symp. Cornell University .
   Google Scholar
• Shallenberger , R. S. , Acree , T. E. and Lee , C. Y. 1969 . Sweet taste of D‐ and L‐sugars and amino acids and the steric nature of their receptor . site,Nature , 221 : 555
   PubMed Web of Science ®Google Scholar
• Shallenberger , R. S. and Acree , T. E. 1969 . Molecular structure and sweet taste . J. Agric. Food Chem. , 17 : 701
   Web of Science ®Google Scholar
• Henkin , R. I. and Shallenberger , R. S. 1970 . Aglycogeusia: the inability to recognize sweetness and its possible molecular basis . Nature , 227 : 965
   Google Scholar
• Birch , G. G. and Shallenberger , R. S. 1973 . “ Configuration, conformation and the properties of food sugars ” . In Molecular Structure and Function of Food Carbohydrate , Edited by: Birch , G. G. and Green , L. F. Vol. 9 , London : Applied Science .
   Google Scholar
• Brimacombe , J. , Foster , A. B. , Stacey , M. and Whiffen , D. H. 1958 . Aspects of stereochemistry. I. Properties and reactions of some diols . Tetrahedron , 4 : 351
   Google Scholar
• Marrinan , H. J. and Mann , J. 1954 . A study of infrared spectroscopy of hydrogen bonding in cellulose . J. Appl. Chem. , 4 : 204
   Google Scholar
• Kuhn , L. P. 1952 . The hydrogen bond. I. Intra‐ and intermolecular hydrogen bonds in alcohols . J. Am. Chem. Soc , 74 : 2492
   Web of Science ®Google Scholar
• Cole , A. R. H. and Jefferies , P. R. 1956 . Stereochemistry of cyclohexane derivatives. V. Infrared spectra and conformations of stereoisomers of 1,2‐diols . J. Chem. Soc. , : 4391
   Google Scholar
• Birch , G. G. , Lee , C. K. and Rolfe , E. J. 1970 . Organoleptic effects in sugar structures . J. Sci. Food Agric. , 21 : 650
   Google Scholar
• Birch , G. G. 1970 . α,α‐Trehalose as an Ideal Substrate for Organoleptic Studies . paper presented on Trehalose Day in connection with the 5th Int. Symp. Carbohydrate Chemistry . 1970 , Paris.
   Google Scholar
• Birch , G. G. 1970 . Mushroom sugar in food technology, Process . Biochem. , 5 : 9
   Google Scholar
• Birch , G. G. 1973 . Mushroom sugar . Plant Foods for Man , 1 : 49
   Google Scholar
• Birch , G. G. 1963 . Trehaloses . Adv. Carbohydr. Chem. , 18 : 201
   PubMed Web of Science ®Google Scholar
• Birch , G. G. and Richardson , A. C. 1968 . Chemical modification of trehalose and determination of the conformation of hexa‐O‐acetyl‐6,6'‐dideoxy trehalose . Carbohydr. Res. , 8 : 411
   Google Scholar
• Brown , G. M. , Rohner , D. C. , Berking , B. , Beevers , C. A. , Gould , R. O. and Simpson , R. 1972 . The crystal structure of α,α‐trehalose dihydrate from three independent X‐ray determinations . Acta Crystallogr. , 28 : 3145
   Google Scholar
• Birch , G. G. , Lee , C. K. and Lindley , M. G. 1975 . The stereochemistry of sweetness . Staerke , 27 : 51
   Google Scholar
• Kollonitsch , V. 1970 . Sucrose Chemicals , 63 New York : International Sugar Research Foundation .
   Google Scholar
• Evans , D. R. 1963 . “ Chemical structure and stimulation by carbohydrate ” . In Olfaction and Taste , Edited by: Zotterman , Y. Vol. 1 , 165 Oxford : Pergamon Press .
   Google Scholar
• Bitch , G. G. , Cowell , N. D. and Eyton , D. 1970 . A quantitative investigation of Shallenberger's sweetness hypothesis . J. Food Technol. , 5 : 277
   Google Scholar
• Birch , G. G. , Green , L. F. and Coulson , C. B. 1970 . Glucose Syrups and Related Carbohydrates , London : Elsevier .
   Google Scholar
• Birch , G. G. and Lee , C. K. 1971 . “ The chemical basis of sweetness in model sugars ” . In Sweetness and Sweeteners , Edited by: Birch , G. G. , Green , L. F. and Coulson , C. B. London : Applied Science .
   Google Scholar
• Birch , G. G. and Lindley , M. G. 1973 . Structural functions of taste in the sugar series. Effects of aglycones on the sensory properties of simple glycoside structures . J. Food Sci. , 38 : 665
   Web of Science ®Google Scholar
• Kier , L. B. 1972 . A molecular theory of sweet taste . J. Pharm. Sci. , 61 : 1394
   PubMed Web of Science ®Google Scholar
• Holtje , H. D. and Kier , L. B. 1974 . Sweet taste receptor studies using model interaction energy calculations . J. Pharm. Sci. , 63 : 1722
   PubMedGoogle Scholar
• Kier , L. B. Structure‐taste Relationships in Chemoreception . Proc. 2nd ECRO Minisymposium . Theoretical studies of the sweet taste glucophore , Edited by: Schüdel , P. and Solms , J. Zurich : Wadenswil .
   Google Scholar
• Shallenberger , R. S. and Birch , G. G. 1975 . Sugar Chemistry , New York : Avi .
   Google Scholar
• Schutz , H. G. and Pilgrim , F. J. 1957 . Differential sensitivity in gustation . J. Exp. Psychol. , 54 : 41
   PubMedGoogle Scholar
• Moskowitz , H. R. 1970 . Sweetness and intensity of artificial sweeteners . Percept. Psychophys. , 8 : 40
   Web of Science ®Google Scholar
• Moskowitz , H. R. 1970 . Ratio scales of sugar sweetness . Percept. Psychophys. , 7 : 315
   Web of Science ®Google Scholar
• Birch , G. G. , Cowell , N. D. and Young , R. H. 1972 . Structural basis of and interaction between sweetness and bitterness in sugars . J. Sci. Food Agric. , 23 : 1207
   Google Scholar
• Acton , E. M. , Christensen , J. E. , Stone , G. and Goodman , L. 1968 . Synthesis and taste properties of an N‐(glucose)‐saccharin compound . Experientia , 24 : 998
   Google Scholar
• Krbechek , L. , Inglett , G. , Holik , M. , Dowling , B. , Wagner , R. and Riter , R. 1968 . Dihydrochalcones. Synthesis of potential sweetening agents . J. Agric. Food Chem. , 16 : 108
   Google Scholar
• Horowitz , R. M. and Gentili , B. U.S. Patent 3,087,821 . 1963 .
   Google Scholar
• Horowitz , R. M. 1964 . “ Relations between the taste and structure of some phenolic glycosides ” . In Biochemistry of Phenolic Compounds , Edited by: Harborne , J. B. 545 New York : Academic Press .
   Google Scholar
• Horowitz , R. M. and Gentili , B. 1961 . Phenolic glycosides of grapefruit: a relation between bitterness and structure . Arch. Biochem. , 92 : 191
   Google Scholar
• Horowitz , R. M. and Gentili , B. 1969 . Taste and structure in phenolic glycosides. A review . J. Agric. Food Chem. , 17 : 696
   Web of Science ®Google Scholar
• Horowitz , R. M. and Gentili , B. 1971 . “ Dihydrochalcone sweeteners ” . In Sweetness and Sweeteners , Edited by: Birch , G. G. , Green , L. F. and Coulson , C. B. 69 London : Applied Science .
   Google Scholar
• Birch , G. G. and Lindley , M. G. 1973 . Structural functions of taste in the sugar series. Cyclohexane polyols as sweet analogues of the sugars . J. Food Sci. , 38 : 1179
   Google Scholar
• Birch , G. G. Structure activity relationships in the taste of sugar molecules . Proc. 2nd ECRO Minisymposium . Structure Activity Relationships in Chemoreception , Edited by: Schudel , P. and Solms , J. Zurich : Wädenswil .
   Google Scholar
• Hodge , J. E. , Goodwin , J. C. and Warner , K. A. 1972 . Sweet and Bitter Tastes of Sugar Derivatives of Known Conformation . paper presented at 6th Int. Symp. on Carbohydrate Chemistry . 1972 , Madison, Wisc..
   Google Scholar
• Hodge , J. E. 1973 . Synthesis of methyl 4,6‐O‐methylene‐D‐glycopyranosides . Carbohydr. Res. , 29 : 222
   Google Scholar
• Hodge , J. E. 1967 . “ Origin of flavour in foods ” . In Chemistry and Physiology of Flavours , Edited by: Schultz , H. W. , Day , E. A. and Libbey , L. M. Westport, Conn. : Avi .
   Google Scholar
• van den Ouwieland , G. A. M. and Peer , H. G. 1975 . Components contributing to beef flavour, volatile compounds produced by the reaction of 4‐hydroxy‐5‐methyl‐3(2H)‐furanone and its analogue with hydrogen sulphide . J. Agric. Food Chem. , 230 : 452
   Google Scholar
• Birch , G. G. and Lee , C. K. 1974 . Structural functions of taste in the sugar series. Sensory properties of deoxy sugars . J., Food Sci. , 39 : 947
   Google Scholar
• Birch , G. G. , Lee , C. K. and Richardson , A. C. 1974 . Chemical modification of trehalose. XV. The synthesis of 4,4’ ‐dideoxy and 4,4’: 6,6’ ‐tetradeoxy analogues . Carbohydr. Res. , 36 : 97
   Google Scholar
• Shallenberger , R. S. 1973 . Molecular structure of compounds and the chemical nature of receptor sites for the chemical senses . Proc. 5th Int. Congr. Pharmacol. 1973 , San Francisco Karger, Basel. Pharmacology and the Future of Man , pp. 5
   Google Scholar
• Lindley , M. G. and Birch , G. G. 1975 . Structural functions of taste in the sugar series . J. Sci. Food Agric. , 26 : 117
   Google Scholar
• Lindley , M. G. , Birch , G. G. and Khan , R. 1976 . Sweetness of sucrose and xylitol. Structural considerations . J. Sci Food Agric. , 27 : 140
   PubMedGoogle Scholar
• Lindley , M. G. , Birch , G. G. and Khan , R. 1975 . Synthesis of methyl ethers of sucrose . Carbohydr. Res. , 43 : 360
   Google Scholar
• Brown , G. M. and Levy , H. M. 1963 . Sucrose: precise determination of crystal and molecular structure by neutron diffraction . Science , 19 : 921
   Google Scholar
• Lindley , M. G. , Shallenberger , R. S. and Whistler , R. L. in press . Comparison of the sweetness of glucose and fructose with their ring‐thio analogues . J. Food Sci. ,
   Google Scholar
• Fischer , H. O. L. and Mildbrand , M. 1924 . Uber Dioxy‐aceton . Ber , 57 : 707
   Google Scholar
• Arrequin , B. and Taboada , J. 1970 . Gas chromatography of trimethylsilyl sugars at various temperatures . J. Chromatogr. Sci. , 8 : 187
   Google Scholar
• Lee , C. K. , Mattai , S. E. and Birch , G. G. 1975 . Structural functions of taste in the sugar series. Sugar‐amino acid interaction as an index of sweetness . J. Food Sci. , 40 : 390
   Google Scholar
• Tsuzuki , Y. and Yamashita , A. 1968 . History of the chemistry of taste in Japan . Nippon Kagakusi Gakkai Shi , 7 : 1
   Google Scholar
• Shallenberger , R. S. 1971 . “ Molecular structure and taste ” . In Gustation and Olfaction , Edited by: Ohloff , G. and Thomas , A. F. 126 New York : Academic Press .
   Google Scholar
• Lee , C. K. and Birch , G. G. 1975 . Structural functions of taste in the sugar series. Gustatory properties of anhydro sugars . J. Food Sci. , 40 : 784
   Google Scholar
• Khan , R. 1972 . Sucrochemistry. III. I1, 6,6'‐Tri‐O‐tosyl sucrose and its conversion to 11,4’: 3,6: 31 ,6'‐trianhydro‐sucrose . Carbohydr. Res. , 22 : 441
   Google Scholar
• Lee , C. K. and Birch , G. G. in press . Structural functions of taste in the sugar series. Taste properties of ketoses . J. Pharm. Sci. ,
   Google Scholar
• Siddiqui , I. R. 1970 . The sugars of honey . Adv. Carbohydr. Chem. Biochem. , 25 : 285
   Google Scholar
• Martin , C. M. and Reuter , F. H. 1949 . Isolation of a pectic substance from passion fruit (Passiflora edulis) . Nature , 164 : 407
   Google Scholar
• Begbie , R. and Richtmyer , N. K. 1966 . The isolation of some heptoses, heptuloses, octuloses and nonuloses from Primula officinalis Jacq . Carbohydr. Res. , 2 : 272
   Google Scholar
• Johansson , L and Richtmyer , N. K. 1970 . The isolation of both a talo‐heptulose and an allo‐heptulose from the avocado. Some new paper‐chromatographic data on heptuloses . Carbohydr. Res. , 13 : 461
   Google Scholar
• Lee , C. K. and Birch , G. G. 1975 . Structural functions of taste in the sugar series; binding characteristics of disaccharides . J. Sci. Food Agric. , 26 : 1513
   Google Scholar
• Steinhardtt , R. G. , Calcin , A. D. and Dodd , E. A. 1962 . Taste structure correlation with α‐D‐mannose and β‐D‐mannose . Science , 135 : 367
   Google Scholar
• Birch , G. G. and Kheiri , M. S. A. 1970 . “ The carbohydrates of glucose syrup ” . In Glucose Syrups and Related Carbohydrates , Edited by: Birch , G. G. , Green , L. F. and Coulson , C. B. 31 London : Elsevier .
   Google Scholar
• Pflumm , W. W. 1972 . “ Molecular structure and stimulating effectiveness of oligosaccharides and glycosides ” . In Olfaction and Taste , Edited by: Schneider , E. Vol. 4 , 364 Oxford : Pergamon Press .
   Google Scholar
• Hodge , J. E. and Inglett , G. E. 1973 . Structural Aspects of Glycosidic Sweeteners Containing (1’ ‐2)‐linked Disaccharides . paper presented at the Symp. on Sweeteners at the 165th Meet. American Chemical Society . 1973 , Dallas.
   Google Scholar
• Dick , W. E. Jr. , Hodge , J. E. and Inglett , G. E. 1974 . Structure‐taste relationships in (l'‐2)‐linked disaccharides . Carbohydr. Res. , 36 : 319
   Google Scholar
• Rader , C. P. , Tihanyi , S. G. and Zienty , F. B. 1967 . A study of the true taste of saccharin . J. Food Sci , 32 : 357
   Google Scholar
• Birch , G. G. and Lee , C. K. in press . Structural functions of taste in the sugar series. Structural basis of bitterness in sugar analogues . J. Food Sci. ,
   Google Scholar
• Kubota , T. and Kubo , I. 1969 . Bitterness and chemical structure . Nature , 223 : 97
   Google Scholar
• Dastoli , F. R. and Price , S. 1966 . Sweet‐sensitive protein from bovine taste buds: isolation and assay . Science , 154 : 905
   PubMed Web of Science ®Google Scholar
• Hiji , Y. , Kobayashi , N. and Sato , M. 1971 . Sweet sensitive protein from the rat tongue: its interaction with various sugars . Comp. Biochem. Physiol. B , 39 : 367
   Google Scholar
• Hiji , Y. , Kobayashi , N. and Sato , M. 1968 . A sweet‐sensitive protein from the tongue of the rat . Kumamoto Med. J. , 21 : 137
   Google Scholar
• Cagan , R. H. 1971 . “ Counterparts of gustatory receptors ” . In Gustation and Olfaction , Edited by: Ohloff , G. and Thomas , A. F. 243 New York : Academic Press .
   Google Scholar
• Cagan , R. H. 1974 . “ Biochemistry of sweet sensation ” . In Sugars and Nutrition , Edited by: Sipple , H. L. and McNutt , K. W. 19 New York : Academic Press .
   Google Scholar
• Arshid , F. M. , Giles , C. H. , McLure , E. C. , Ogilvie , A. and Rose , T. J. 1955 . Studies of hydrogen bond formation. Part 2. The use of refractive index measurement to detect intermolecular complex formation in solution . J. Chem. Soc. , : 67
   Google Scholar
• Cagan , R. H. 1971 . Biochemical studies of taste sensation. I. Binding of 14C‐labelled sugars to bovine taste papillae . Biochim. Biophys. Acta , 252 : 199
   PubMedGoogle Scholar
• Dastoli , F. R. , Lopiekes , D. V. and Price , S. 1968 . A sweet sensitive protein from bovine taste buds. Purification and partial characterisation . Biochemistry , 7 : 1160
   PubMed Web of Science ®Google Scholar
• Dastoli , F. R. , Lopiekes , D. V. and Doig , A. R. 1968 . Bitter sensitive protein from porcine taste buds . Nature , 217 : 884
   Google Scholar
• Koyama , N. and Kurihara , K. 1971 . Do unique proteins exist in taste buds . J. Gen. Physiol , 57 : 297
   Google Scholar
• Nofre , C. and Sabadie , J. 1972 . A propos de la proteine linguale dite “sensible aux sucres,”; . C.R. Acad. Sci. Ser. D , 274 : 2913
   Google Scholar
• Price , S. and Hogan , R. M. 1967 . “ Glucose dehydrogenase activity of a “sweet‐sensitive protein”; from bovine tongues ” . In Olfaction and Taste , Edited by: Pfaffmann , C. Vol. 3 , 397 Oxford : Pergamon Press .
   Google Scholar
• Hansen , K. α‐Glucosidases as sugar receptor proteins in flies . Proc. 2nd ECRO Minisymposium . Structure‐activity Relationships in Chemoreception , Edited by: Schüdel , P. and Solms , I. Zurich : Wädenswil .
   Google Scholar
• Kijima , H. 1976 . Specificity of two receptor sites ana identification of receptor molecule in sugar receptor of flies . Proc. 2nd ECRO Minisymposium . 1976 , Zurich. Structure‐activity Relationships in Chemoreception , Edited by: Schudel , P. and Solms , J. Wadenswil .
   Google Scholar
• Hiji , Y. , Kobayashi , N. and Sato , M. 1968 . A sweet‐sensitive protein from the tongue of the rat . Kumamoto Med. J. , 20 : 137
   Google Scholar
• Hiji , Y. 1975 . Selective elimination of taste responses to sugars by proteolytic enzymes . Nature , 256 : 427
   Google Scholar
• Biester , A. , Wood , M. W. and Wahlin , C. S. 1925 . Carbohydrate studies. I. The relative sweetness of pure sugars . Am. J. Psychol. , 73 : 387
   Google Scholar
• Price , S. 1969 . Chemoreceptor proteins from taste buds . J. Agric. Food Chem. , 17 : 709
   Google Scholar
• Amerine , M. A. , Pangborn , R. M. and Roessler , E. B. 1965 . Principles of Sensory Evaluation of Food , New York : Academic Press .
   Google Scholar
• Spencer , H. 1971 . “ Taste panels and the measurement of sweetness ” . In Sweetness and Sweeteners , Edited by: Birch , G. G. , Green , L. F. and Coulson , C. B. London : Applied Science .
   Google Scholar
• Dahlberg , A. C. and Penczek , E. S. 1941 . The relative sweetness of sugars as affected by concentration . N. Y. State Agric. Exp. Sta. Bull. , : 258
   Google Scholar
• Kiesow , F. 1903 . A contribution to the question of reaction times in taste perception . Z. Psychol. Physiol. Sinnesorgane , 33 : 453
   Google Scholar
• Pfaffmann , C. 1955 . Gustatory nerve impulses in rat, cat and rabbits . J. Neurophysiol , 18 : 429
   PubMed Web of Science ®Google Scholar
• Inglett , G. E. 1971 . “ Intense sweetness of natural origin ” . In Sweetness and Sweeteners , Edited by: Birch , G. G. , Green , L. F. and Coulson , C. B. 32 London : Applied Science .
   Google Scholar
• Solms , J. Structure‐activity Relationships in Chemoreception . Proc. 2nd ECRO Minisymposium . Edited by: Schudel , P. and Solms , J. Zurich : Wadenswil .
   Google Scholar
• Moskowitz , H. R. 1975 . Applications of sensory measurement to food evaluations. I. Threshold, category and discrimination scales . Lebensm. Wiss. Technol. , 8 : 245
   Google Scholar
• Moskowitz , H. R. 1975 . Applications of sensory measurement to food evaluations. IL Methods of ratio scaling . Lebensm. Wiss. Technol. , 8 : 249
   Google Scholar
• Moskowitz , H. R. 1972 . Scales of subjective viscosity and fluidity of gum solutions . J. Texture Stud. , 3 : 89
   Google Scholar
• Watson , R. 1971 . “ The psychology of sweetness ” . In Sweetness and Sweeteners , Edited by: Birch , G. G. , Green , L. F. and Coulson , C. B. London : Applied Science .
   Google Scholar
• Diamant , H. , Oakley , B. , Ström , L. , Wells , C. and Zotterman , Y. 1965 . A comparison of neural and psychophysical responses to taste stimuli in man . Acta Physiol. Scand. , 64 : 67
   PubMedGoogle Scholar
• Warren , R. M. and Pfaffinann , C. 1959 . Suppression of sweet sensitivity by potassium gymnemate . J. Appl. Physiol. , 14 : 40
   PubMedGoogle Scholar
• Birch , G. G. and Mylvaganam , A. R. 1976 . Evidence for the proximity of sweet and bitter receptor sites . Nature , 26 : 632
   Google Scholar
• Beets , M. G. J. 1970 . Relation of Chemical Structure to Odor and Taste . Proc. 3rd Int. Congr. Food Science and Technology . 1970 , Chicago.
   Google Scholar
• Glaser , D. 1972 . The reactions of saccharin, dulcin and distilled water in some primates . Folia Primatol. , 18 : 433
   Google Scholar