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Original Articles

Food Ingredients as Anti-Obesity Agents: A Review

, , , , &
Pages 929-942 | Published online: 14 Jun 2013

REFERENCES

  • Adan , R. A. H. , Vanderschuren , L. J. M. J. and la Fleur , S. E. 2008 . Anti-obesity drugs and neural circuits of feeding . Trends Pharmacol. Sci. , 29 ( 4 ) : 208 – 217 .
  • Anderson , J. W. 2008 . “ Dietary fiber and associated phytochemicals in prevention and reversal of diabetes ” . In Nutraceuticals, Glycemic Health and Type 2 Diabetes , Edited by: Pasupuleti , V. K. and Anderson , J. W. 111 – 142 . Iowa : Blackwell Publishing Professional .
  • Arterburn , D. E. , Crane , P. K. and Veenstra , D. L. 2004 . The efficacy and safety of sibutramine for weight loss: A systematic review . Arch. Intern. Med. , 164 : 994 – 1003 .
  • Astrup , A. , Kristensen , M. , Gregersen , N. T. , Belza , A. , Lorenzen , J. K. , Due , A. and Larsen , T. M. 2010 . Can bioactive foods affect obesity? . Ann. N. Y. Acad. Sci. , 1190 : 25 – 41 .
  • Azain , M. J. , Hausman , D. B. , Sisk , M. B. , Flatt , W. P. and Jewel , D. E. 2000 . Dietary conjugated linoleic acid reduces rat adipose tissue cell size rather than cell number . J. Nutr. , 130 : 1548 – 1554 .
  • Bacher , H. P. , Shepherd , G. M. and Legler , U. F. 2009 . Pharmacological therapies of obesity: A review of current treatments options . Biomol. Ther. , 17 ( 4 ) : 348 – 352 .
  • Baer , R. J. , Ryali , J. , Schingoethe , D. J. , Kasperson , K. M. , Donovan , D. C. , Hippen , A. R. and Franklin , S. T. 2001 . Composition and properties of milk and butter from cows fed fish oil . J. Dairy Sci. , 84 : 345 – 353 .
  • Banegas , J. R. , López-García , E. , Gutiérrez-Fisac , J. L. , Guallar-Castillón , P. and Rodríguez-Artalejo , F. 2003 . A simple estimate of mortality attributable to excess weight in the European Union . Eur. J. Clin. Nutr. , 57 : 201 – 208 .
  • Barr , S. I. 2003 . Increased dairy product or calcium intake: Is body weight or composition affected in humans? . J. Nutr. , 133 : 245S – 248S .
  • Belury , M. A. , Mahon , A. and Banni , S. 2003 . The conjugated linoleic acid (CLA) isomer, t10c12-CLA, is inversely associated with changes in body weight and serum leptin in subjects with type 2 diabetes mellitus . J. Nutr. , 133 : 257S – 260S .
  • Belza , A. , Frandsen , E. and Kondrup , J. 2007 . Body fat loss achieved by stimulation of thermogenesis by a combination of bioactive food ingredients: A placebo-controlled, double-blind 8-week intervention in obese subjects . Int. J. Obesity. , 31 : 121 – 130 .
  • Belza , A. , Gille , M.-B. , Schultz John , S. and Kondrup , J. 2009 . The β-adrenergic antagonist propranolol partly abolishes thermogenic response to bioactive food ingredients . Metabolism , 58 : 1137 – 1144 .
  • Bessesen , D. H. 2008 . Update on obesity . J. Clin. Endocrinol. Metab. , 93 : 2027 – 2034 .
  • Bhathena , S. J. and Velasquez , M. T. 2002 . Beneficial role of dietary phytoestrogens in obesity and diabetes . Am. J. Clin. Nutr. , 76 : 1191 – 1201 .
  • Biesalski , H.-K. , Dragsted , L. O. , Elmadfa , I. , Grossklaus , R. , Müller , M. , Schrenk , D. , Walter , P. and Weber , P. 2009 . Bioactive compounds: Definition and assessment of activity . Nutrition , 25 : 1202 – 1205 .
  • Blankson , H. , Stakksetad , J. A. , Fagertun , H. , Thom , E. , Wadstein , J. and Gudmundsen , O. 2000 . Conjugated linoleic acid reduces body fat mass in overweight and obese humans . J. Nutr. , 130 : 2943 – 2948 .
  • Borneo , R. , Kocer , D. , Ghai , G. , Tepper , B. J. and Karwe , M. V. 2007 . Stability and consumer acceptance of long-chain omega-3 fatty acids (eicosapentaenoic acid, 20:5, n-3 and docosahexaenoic acid, 22:6, n-3) in cream-filled sandwich cookies . J. Food Sci. , 72 : S49 – S54 .
  • Bozkurt , H. 2006 . Utilization of natural antioxidants: Green tea extract and Thymbra spicata oil in Turkish dry-fermented sausage . Meat Sci , 73 : 442 – 450 .
  • Bray , G. A. and Greenway , F. L. 2007 . Pharmacological treatment of the overweight patient . Pharmacol. Rev. , 59 : 151 – 184 .
  • Buckley , J. D. and Howe , P. R. C. 2009 . Anti-obesity effects of long-chain omega-3 polyunsaturated fatty acids . Obes. Rev. , 10 : 648 – 659 .
  • Cani , P. D. and Delzenne , N. M. 2009 . The role of the gut microbiota in energy metabolism and metabolic disease . Curr. Pharm. Design. , 15 ( 13 ) : 1546 – 1558 .
  • Cani , P. D. , Delzenne , N. M. , Amar , J. and Burcelin , R. 2008 . Role of gut microflora in the development of obesity and insulin resistance following high-fat diet feeding . Pathol. Biol. , 56 ( 5 ) : 305 – 309 .
  • Cardoso , C. , Mendes , R. and Nunes , M. L. 2007 . Dietary fibers’ effect on the textural properties of fish heat-induced gels . J. Aquat. Food Prod. T. , 16 : 19 – 30 .
  • Cardoso , C. , Mendes , R. , Pedro , S. , Vaz-Pires , P. and Nunes , M. L. 2010 . Quality changes during storage of minced fish products containing dietary fiber and fortified with ω3 fatty acids . Food Sci Technol Int , 16 : 31 – 42 .
  • Cederroth , C. R. and Nef , S. 2009 . Soy, phytoestrogens and metabolism: A review . Mol. Cell. Endocrinol. , 304 : 30 – 42 .
  • Choi , S. H. , Kwon , H. C. , An , D. J. , Park , J. R. and Oh , D. H. 2003 . Nitrite contents and storage properties of sausage added with green tea powder . Korean J. Food Sci. An. , 23 : 299 – 308 .
  • Christensen , R. , Lorenzen , J. K. , Svith , C. R. , Bartels , E. M. , Melanson , E. L. , Saris , W. H. , Tremblay , A. and Astrup , A. 2009 . Effect of calcium from dairy and dietary supplements on faecal fat excretion: A meta-analysis of randomised controlled trials . Obes. Rev. , 10 : 475 – 486 .
  • Clifton , P. M. , Noakes , M. , Sullivan , D. , Erichsen , N. , Ross , D. , Annison , G. , Fassoulakis , A. , Cehun , M. and Nestel , P. 2004 . Cholesterol-lowering effects of plant sterol esters differ in milk, yoghurt, bread and cereal . Eur. J. Clin. Nutr. , 58 : 503 – 509 .
  • Connolly , H. M. , Crary , J. L. , McGoon , M. D. , Hensrud , D. D. , Edwards , B. S. , Edwards , W. D. and Schaff , H. V. 1997 . Valvular heart disease associated with fenfluramine-phentermine . N. Engl. J. Med. , 337 : 581 – 588 .
  • Covas , M. I. , Ruiz-Gutiérrez , V. , De la Torre , R. , Kafatos , A. , Lamuela-Raventós , R. M. , Osada , J. , Owen , R. W. and Visioli , F. 2006 . Minor components of olive oil: Evidence to date of health benefits in humans . Nutr. Rev. , 64 : 20 – 30 .
  • Czernichow , S. , Lee , C. M. Y. , Barzi , F. , Greenfield , J. R. , Baur , L. A. , Chalmers , J. , Woodward , M. and Huxley , R. R. 2010 . Efficacy of weight loss drugs on obesity and cardiovascular risk factors in obese adolescents: A meta-analysis of randomized controlled trials . Obes. Rev. , 11 : 150 – 158 .
  • Dalais , F. S. , Ebeling , P. R. , Kotsopoulos , D. , McGrath , B. P. and Teede , H. J. 2003 . The effects of soy protein containing isoflavones on lipids and indices of bone resorption in postmenopausal women . Clin. Endocrinol. , 58 : 704 – 709 .
  • de Vos , P. , Faas , M. M. , Spasojevic , M. and Sikkema , J. 2010 . Encapsulation for preservation of functionality and targeted delivery of bioactive food components . Int. Dairy J. , 20 : 292 – 302 .
  • Derbyshire , E. 2010 . Does adult calcium intake influence body composition? A review . Nutr Food Sci , 40 ( 5 ) : 494 – 503 .
  • DeLany , J. P. and West , D. B. 2000 . Changes in body composition with conjugated linoleic acid . J. Am. Coll. Nutr. , 19 : 487S – 493S .
  • Di Marzo , V . 2008 . CB1 receptor antagonism: Biological basis for metabolic effects . Drug Discov. Today. , 13 : 1026 – 1041 .
  • Di Marzo , V. , Bifulco , M. and De Petrocellis , L. 2004 . The endocannabinoid system and its therapeutic exploitation . Nat. Rev. Drug Discov , 3 : 771 – 784 .
  • DiBaise , J. K. , Zhang , H. , Crowell , M. D. , Krajmalnik-Brown , R. , Decker , G. A. and Rittmann , B. E. 2008 . Gut microbiota and its possible relationship with obesity . Mayo Clin. Proc. , 83 ( 4 ) : 460 – 469 .
  • Drusch , S. and Mannino , S. 2009 . Patent-based review on industrial approaches for the microencapsulation of oils rich in polyunsaturated fatty acids . Trends Food Sci. Tech. , 20 : 237 – 244 .
  • Dulloo , A. G. , Seydoux , J. , Girardier , L. , Chantre , P. and Vandermander , J. 2000 . Green tea and thermogenesis: Interactions between catechin-polyphenols, caffeine and sympathetic activity . Int. J. Obes. , 24 : 252 – 258 .
  • European Medicines Agency, EMEA . 2008 . The European Medicines Agency recommends suspension of the marketing authorization of Acomplia . [press release] Oct 23, 2008. Available from: http://www.emea.europa.eu (Doc.Ref.: EMEA/CHMP/537777/2008)
  • Fernández-López , J. , Sendra , E. , Sayas-Barberá , M. E. , Navarro , C. and Pérez-Alvarez , J. A. 2008 . Physicochemical and microbiological profiles of “Salchichón” (Spanish dry-fermented sausage) enriched with orange fiber . Meat Sci , 80 : 410 – 417 .
  • Froyland , L. , Madsen , L. , Vaagenes , H. , Totland , G. K. , Auwerx , J. , Kryui , H. , Staels , B. and Berge , R. K. 1997 . Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism . J. Lipid Res. , 38 : 1851 – 1858 .
  • González-Molina , Moreno , D. A. and García-Viguera , C. 2008 . Aronia-enriched lemon juice: A new highly antioxidant beverage . J. Agric. Food Chem , 56 : 11327 – 11333 .
  • Graham , I. A. , Larson , T. and Napier , J. A. 2007 . Rational metabolic engineering of transgenic plants for biosynthesis of omega-3 polyunsaturates . Curr. Opin. Biotech. , 18 : 142 – 147 .
  • Guo , W. , Xie , W. , Lei , T. and Hamilton , J. A. 2005 . Eicosapentaenoic acid, but not oleic acid, stimulates beta-oxidation in adipocytes . Lipids , 40 : 815 – 821 .
  • Halford , J. C. G. , Boyland , E. J. , Cooper , S. J. , Dovey , T. M. , Huda , M. S. B. , Dourish , C. T. , Dawson , G. R. and Wilding , J. P. H. 2010 . The effects of sibutramine on the microstructure of eating behavior and energy expenditure in obese women . J. Psychopharmacol. , 24 : 99 – 109 .
  • Han , J.-S. , Hong , H.-D. and Kim , S.-R. 2007 . Changes in isoflavone content and mass balance during soybean processing . Food Sci. Biotechnol. , 16 ( 3 ) : 426 – 433 .
  • Han , L.-K. , Kimura , Y. , Kawashima , M. , Takaku , T. , Hayashi , T. , Zheng , Y.-N. and Okuda , H. 2001 . Anti-obesity effects in rodents of dietary teasaponin, a lipase inhibitor . Int. J. Obesity. , 25 ( 10 ) : 1459 – 1464 .
  • Han , L.-K. , Zheng , Y.-N. , Yoshikawa , M. , Okuda , H. and Kimura , Y. 2005 . Anti-obesity effects of chikusetsusaponins isolated from Panax japonicas rhizomes . BMC Complem. Altern. M , 5 : 9
  • Hansel , B. , Nicolle , C. , Lalanne , F. , Tondu , F. , Lassel , T. , Donazzolo , Y. , Ferrières , J. , Krempf , M. , Schlienger , J.-L. , Verges , B. , Chapman , M. J. and Bruckert , E. 2007 . Effect of low-fat, fermented milk enriched with plant sterols on serum lipid profile and oxidative stress in moderate hypercholesterolemia . Am. J. Clin. Nutr. , 86 : 790 – 796 .
  • He , J. , Streiffer , R. H. , Muntner , P. , Krousel-Wood , M. A. and Whelton , P. K. 2004 . Effect of dietary fiber intake on blood pressure: A randomized, double-blind, placebo controlled trial . J. Hypertens. , 22 : 73 – 80 .
  • Heal , D. J. , Aspley , S. , Prow , M. R. , Jackson , H. C. , Martin , K. F. and Cheetham , S. C. 1998 . Sibutramine: A novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine . Int. J. Obesity. , 22 : S18 – S28 .
  • Heal , D. J. , Gosden , J. and Smith , S. L. 2009 . Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders . Br. J. Clin. Pharmacol. , 68 ( 6 ) : 861 – 874 .
  • Heaton , K. W. 1973 . Food fibre as an obstacle to energy intake . Lancet , 2 : 1418 – 1421 .
  • Heinemann , T. , Kullak-Ublick , G. A. and Pietruck , B. J. 1991 . Mechanisms of action of plant sterols on inhibition of cholesterol absorption. Comparison of sitosterol and sitostanol . Eur. J. Clin. Pharmacol. , 40 : 59S – 63S .
  • Horn , A. F. , Nielsen , N. S. and Jacobsen , C. 2009 . Addition of caffeic acid, ascorbyl palmitate or γ-tocopherol to fish oil enriched energy bars affects lipid oxidation differently . Food Chem , 112 : 412 – 420 .
  • Huang , Y.-W. , Liu , Y. , Dushenkov , S. , Ho , C.-T. and Huang , M.-T. 2009 . Anti-obesity effects of epigallocatechin-3-gallate, orange peel extract, black tea extract, caffeine and their combinations in a mouse model . J. Funct. Foods. , 1 : 304 – 310 .
  • Hursel , R. , Viechtbauer , W. and Westerterp-Plantenga , M. S. 2009 . The effects of green tea on weight loss and weight maintenance: A meta-analysis . Int. J. Obesity. , 33 : 956 – 961 .
  • Hsu , Y.-W. , Chu , D.-C. , Ku , P.-W. , Liou , T.-H. and Chou , P. 2010 . Pharmacotherapy for obesity: Past, present and future . J. Exp. Clin. Med. , 2 ( 3 ) : 118 – 123 .
  • Ikeda , I. and Sugano , M. 1998 . Inhibition of cholesterol absorption by plant sterols for mass intervention . Curr. Opin. Lipidol. , 9 : 527 – 531 .
  • Isidro , M. L. and Cordido , F. 2010 . Approved and off-label uses of obesity medications, and potential new pharmacologic treatments options . Pharmaceuticals , 3 : 125 – 145 .
  • Ito , Y. , Ichikawa , T. , Morohoshi , Y. , Saegusa , Y. and Ishihara , K. 2008 . Effect of tea catechins on body fat accumulation in rats fed a normal diet . Biomed. Res. , 29 ( 1 ) : 27 – 32 .
  • Jacobsen , C. , Hartvigsen , K. , Lund , P. , Meyer , A. S. , Adler-Nissen , J. , Holstborg , J. and Hølmer , G. 1999 . Oxidation in fish oil enriched mayonnaise: 1. Assessment of propyl gallate as antioxidant by discriminant partial least squares regression analysis . Eur. Food Res. Technol , 210 : 13 – 30 .
  • Jacobsen , C. , Hartvigsen , K. , Thomsen , M. K. , Hansen , L. F. , Lund , P. , Skibsted , L. H. , Hølmer , G. , Adler-Nissen , J. and Meyer , A. S. 2001 . Lipid oxidation in fish oil enriched mayonnaise: Calcium disodium ethylenediaminetetraacetate, but not gallic acid, strongly inhibited oxidative deterioration . J. Agric. Food Chem. , 49 : 1009 – 1019 .
  • Jacobsen , R. , Lorenzen , J. K. , Toubro , S. , Krog-Mikkelsen , I. and Astrup , A. 2005 . Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion . Int. J. Obesity. , 29 : 292 – 301 .
  • Jacome-Sosa , M. M. , Lu , J. , Wang , Y. , Ruth , M. R. , Wright , D. C. , Reaney , M. J. , Shen , J. , Field , C. J. , Vine , D. F. and Proctor , S. D. 2010 . Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleico acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR: LA-cp rat . Nutr. Metab , 7 : 60 – 70 .
  • Jackson , C. -J. C. , Dini , J. P. , Lavandier , C. , Rupasinghe , H. P. V. , Faulkner , H. , Poysa , V. , Buzzell , D. and DeGrandis , S. 2002 . Effects of processing on the content and composition of isoflavones during manufacturing of soy beverage and tofu . Process Biochem , 37 : 1117 – 1123 .
  • Jahreis , G. , Kraft , J. , Tischendorf , F. , Schöne , F. and von Loeffelholz , V. 2000 . Conjugated linoleic acids: Physiological effects in animal and man with special regard to body composition . Eur. J. Lipid Sci. Tech. , 102 : 695 – 7103 .
  • James , W. P. T. , Astrup , A. , Finer , N. , Hilsted , J. , Kopelman , P. , Rössner , S. , Saris , W. H. , Van Gaal , L. F. and for the STORM Study Group . 2000 . Effect of sibutramine on weight maintenance after weight loss: A randomised trial . Lancet , 356 : 2119 – 2125 .
  • Jang , E.-H. , Moon , J.-S. , Ko , J. H. , Ahn , C.-W. , Lee , H.-H. , Shin , J.-K. , Park , C.-S. and Kang , J.-H. 2008 . Novel black soy peptides with antiobesity effects: Activation of leptin-like signaling and AMP-activated protein kinase . Int. J. Obesity. , 32 : 1161 – 1170 .
  • Jaziri , I. , Ben Slama , M. , Mhadhbi , H. , Urdaci , M. C. and Hamdi , M. 2009 . Effect of green and black teas (Camellia sinensis L.) on the characteristic microflora of yogurt during fermentation and refrigerated storage . Food Chem , 112 ( 3 ) : 614 – 620 .
  • Jiménez , A. M. , Murcia , M. A. , Parras , P. and Martínez-Tomé , M. 2008 . On the importance of adequately choosing the ingredients of yoghurt and enriched milk for their antioxidant activity . Int. J. Food Sci. Tech. , 43 : 1464 – 1473 .
  • Jiménez-Colmenero , F. 2007 . Healthier lipid approaches in meat-based functional foods. Technological options for replacement of meat fats by non-meat fats . Trends Food Sci. Tech. , 18 : 567 – 578 .
  • Kamisoyama , H. , Honda , K. , Tominaga , Y. , Yokota , S. and Hasegawa , S. 2008 . Investigation of the anti-obesity action of licorice flavonoid oil in diet-induced obese rats . Biosci. Biotechnol. Biochem. , 72 ( 12 ) : 3225 – 3231 .
  • Kim , H. , Choi , S. , Lee , H. J. , Lee , J. H. and Choi , H. 2003 . Suppression of fatty acid synthase by dietary polyunsaturated fatty acids is mediated by fat itself, not by peroxidative mechanism . J. Biochem. Mol. Biol. , 36 : 258 – 264 .
  • Kim , H. K. , Della-Fera , M. , Lin , J. and Baile , C. A. 2006 . Docosahexaenoic acid inhibits adipocyte differentiation and induces apoptosis in 3T3-L1 preadipocytes . J. Nutr. , 136 : 3965 – 3696 .
  • Kim , J.-Y. , Moon , K.-D. , Seo , K.-I. , Park , K.-W. , Choi , M.-S. , Do , G.-M. , Jeong , Y.-K. , Cho , Y.-S. and Lee , M.-K. 2009 . Supplementation of SK1 from platycodi radix ameliorates obesity and glucose intolerance in mice fed a high-fat diet . J. Med. Food. , 12 ( 3 ) : 629 – 636 .
  • Kim , H. J. , Takahashi , M. and Ezaki , O. 1999 . Fish oil feeding decreases mature sterol regulatory element-binding protein 1 (SREBP-1) by down-regulation of SREBP-1c mRNA in mouse liver. A possible mechanism for down-regulation of lipogenic enzyme mRNAs . J. Biol. Chem. , 274 : 25892 – 25898 .
  • Klopotek , Y. , Otto , K. and Böhm , V. 2005 . Processing strawberries to different products alters contents of vitamin C, total phenolics, total anthocyanins, and antioxidant capacity . J. Agric. Food Chem. , 53 : 5640 – 5646 .
  • Kolanowski , W. , Swiderski , F. and Berger , S. 1999 . Possibilities of fish oil application for food products enrichment with ω-3 PUFA . Int. J. Food Sci. Nutr. , 50 ( 1 ) : 39 – 49 .
  • Kolanowski , W. , Swiderski , F. , Jaworska , D. and Berger , S. 2004 . Stability, sensory quality, texture properties and nutritional value of fish oil-enriched spreadable fat . J. Sci. Food Agric. , 84 : 2135 – 2141 .
  • Kovacs , E. M. , Lejeune , M. P. , Nijs , I. and Westerterp-Plantenga , M. S. 2004 . Effects of green tea on weight maintenance after body-weight loss . Br. J. Nutr. , 91 : 431 – 437 .
  • Larsen , T. M. , Toubro , S. and Astrup , A. 2003 . Efficacy and safety of dietary supplements containing conjugated linoleic acid (CLA) for the treatment of obesity-evidence from animal and human studies . J. Lipid Res. , 44 ( 12 ) : 2234 – 2241 .
  • Layman , D. K. 2003 . The role of leucine in weight loss diets and glucose homeostasis . J. Nutr. , 133 : 261S – 267S .
  • Lean , M. E. 2001 . How does sibutramine work? . Int. J. Obes. Relat. Metab. Disord. , 25 : S8 – S11 .
  • Let , M. B. , Jacobsen , C. , Frankel , E. N. and Meyer , A. S. 2007a . Ascorbyl palmitate, gamma-tocopherol, and EDTA affect lipid oxidation in fish oil enriched salad dressing differently . J. Agric. Food Chem. , 55 : 2369 – 2375 .
  • Let , M. B. , Jacobsen , C. , Pham , K. A. and Meyer , A. S. 2005 . Protection against oxidation of fish oil enriched milk emulsions through addition of rapeseed oil or antioxidants . J. Agric. Food Chem. , 53 : 5429 – 5437 .
  • Let , M. B. , Jacobsen , C. , Sørensen , A. D. M. and Meyer , A. S. 2007b . Homogenization conditions affects the oxidative stability of fish oil enriched milk emulsions: Lipid oxidation . J. Agric. Food Chem. , 55 : 1773 – 1780 .
  • Li , M. and Cheung , B. M. Y. 2009 . Pharmacotherapy for obesity . Br. J. Clin. Pharmacol. , 68 ( 6 ) : 804 – 810 .
  • Li , J.-J. , Huang , C. J. and Xie , D. 2008 . Anti-obesity effects of conjugated linoleic acid, docosahexaenoic acid, and eicosapentaenoic acid . Mol. Nutr. Food Res. , 52 : 631 – 645 .
  • Tu , W. , Mojica , W. , Arterburn , D. , Shugarman , L. R. , Hilton , L. , Suttorp , M. , Solomon , V. , Shekelle , P. G. and Morton , S. C. 2005 . Meta-analysis: Pharmacologic treatment of obesity . Ann. Intern. Med. , 142 : 532 – 546 . Li., Z., Maglione, M.
  • Liao , F.-H. , Liou , T.-H. , Chiu , W.-C. , Shieh , M.-J. and Chien , Y.-W. 2010 . Differential effects of high MUFA with high or low P/S ratio (polyunsaturated to saturated fatty acids) on improving hepatic lipolytic enzymes and mediating PPARγ related with lipoprotein lipase and hormone-sensitive lipase of white adipose tissue in diet-induced obese hamster . Int. J. Obesity. , 34 : 1608 – 1617 .
  • Liese , A. D. , Schulz , M. , Fang , F. , Wolever , T. M. S. , D’Agostino , R. B. Jr. , Sparks , K. C. and Mayer-Davis , E. J. 2005 . Dietary glycemic index and glycemic load, carbohydrate and fiber intake, and measures of insulin sensitivity, secretion, and adiposity in the Insulin Resistance Atherosclerosis Study . Diabetes Care , 28 : 2832 – 2838 .
  • Liu , B. H. , Kuo , C. F. , Wang , Y. C. and Ding , S. T. 2005 . Effect of docosahexaenoic acid and arachidonic acid on the expression of adipocyte determination and differentiation-dependent factor 1 in differentiating porcine adipocytes . J. Anim. Sci. , 83 : 1516 – 1525 .
  • Lovegrove , J. A. , Brooks , C. N. , Murphy , M. C. , Gould , B. J. and Williams , C. M. 1997 . Use of manufactured foods enriched with fish oils as a means of increasing long-chain n-3 polyunsaturated fatty acid intake . Brit. J. Nutr , 78 : 223 – 236 .
  • Luff , J. 2007 . Omega-3 and micro-encapsulation technology – Making functional foods taste better for longer . Food Sci. Technolo. , 21 ( 1 ) : 30 – 31 .
  • Lunn , J. and Buttriss , J. L. 2008 . Incorporating omega-3 in the food chain—why, where and how? . Nutr. Bull. , 33 : 250 – 256 .
  • Maeda , H. , Hosokawa , M. , Sashima , T. and Miyashita , K. 2007 . Dietary combination of fucoxanthin and fish oil attenuates the weight gain of white adipose tissue and decreases blood glucose in obese/diabetic KK-Ay mice . J. Agric. Food Chem , 55 : 7701 – 7706 .
  • Mai , V. and Draganov , P. V. 2009 . Recent advances and remaining gaps in our knowledge of associations between gut microbiota and human health . World J. Gastroentero. , 15 ( 1 ) : 81 – 85 .
  • Meadus , W. J. , MacInnis , R. and Dugan , M. E. 2002 . Prolonged dietary treatment with conjugated linoleic acid stimulates porcine muscle peroxisome proliferator activated receptor gamma and glutamine-fructose aminotransferase gene expression in vivo . J. Mol. Endocrinol , 28 : 79 – 86 .
  • Melanson , E. L. , Astrup , A. and Danahoo , W. 2009 . The relationship between dietary fat and fatty acid intake and body weight, diabetes, and the metabolic syndrome . Ann. Nutr. Metab. , 55 : 229 – 243 .
  • Miglio , C. , Chiavaro , E. , Visconti , A. , Fogliano , V. and Pellegrini , N. 2008 . Effects of different cooking methods on nutritional and physico-chemical characteristics of selected vegetables . J. Agric. Food Chem. , 56 : 139 – 147 .
  • Miller , K. B. , Hurst , W. J. , Payne , M. J. , Stuart , D. A. , Apgar , J. , Sweigart , D. S. and Ou , B. 2008 . Impact of alkalization on the antioxidant and flavanol content of commercial cocoa powders . J. Agric. Food Chem. , 56 : 8527 – 8533 .
  • Moghadasian , M. H. 2008 . Advances in dietary enrichment with N-3 fatty acids . Crit. Rev. Food Sci. Nutr. , 48 ( 5 ) : 402 – 410 .
  • Moran , T. H. and Dailey , M. J. 2009 . Minireview: Gut peptides: Targets for antiobesity drug development? . Endocrinology , 150 ( 6 ) : 2526 – 2530 .
  • Moran , T. H. , Smedh , U. , Kinzig , K. P. , Scott , K. A. , Knipp , S. and Ladenheim , E. E. 2005 . Peptide YY (3-36) inhibits gastric emptying and produces acute reductions in food intake in rhesus monkeys . Am. J. Physiol. Regul. Integr. Comp. Physiol. , 288 ( 2 ) : R384 – R388 .
  • Munro , I. C. , Harwood , M. , Hlywka , J. J. , Stephen , A. M. , Doull , J. , Flamm , W. G. and Adlerereutz , H. 2003 . Soy isoflavones: A safety review . Nutr. Rev. , 61 : 1 – 33 .
  • Murakami , K. , Sasaki , S. , Okubo , H. , Takahashi , Y. , Hosoi , Y. and Itabashi , M. 2007 . Dietary fiber intake, dietary glycemic index and load, and body mass index: A cross-sectional study of 3931 Japanese women aged 18–20 years . Eur. J. Clin. Nutr. , 61 : 986 – 995 .
  • Murase , T. , Nagasawa , A. , Suzuki , J. , Hase , T. and Tokimitsu , I. 2002 . Beneficial effects of tea catechins on diet-induced obesity: Stimulation of lipid catabolism in the liver . Int. J. Obesity. , 26 : 1459 – 1464 .
  • Nagao , K. and Yanagita , T. 2005 . Conjugated fatty acids in food and their health benefits . J. Biosci. Bioeng. , 100 ( 2 ) : 152 – 157 .
  • Nakagawa , K. , Kishida , H. , Arai , N. , Nishiyama , T. and Mae , T. 2004 . Licorice flavonoids suppress abdominal fat accumulation and increase in blood glucose level in obese diabetic KK-Ay mice . Biol. Pharm. Bull. , 27 ( 11 ) : 1775 – 1778 .
  • Napier , J. A. and Sayanova , A. 2005 . The production of very-long-chain PUFA biosynthesis in transgenic plants: Towards a sustainable source of fish oils . P. Nutr. Soc. , 64 : 387 – 393 .
  • Neary , M. T. and Batterham , R. L. 2009 . Gut hormones: Implication for the treatment of obesity . Pharmacol. Ther. , 124 : 44 – 56 .
  • Nielsen , N. S. and Jacobsen , C. 2009 . Methods for reducing lipid oxidation in fish-oil-enriched energy bars . Internat. J. Food Sci. Technol. , 44 : 412 – 420 .
  • Nielsen , N. S. , Klein , A. and Jacobsen , C. 2009 . Effect of ingredients on oxidative stability of fish oil-enriched drinking yogurt . Eur. J. Lipid Sci. Tech. , 111 : 337 – 345 .
  • Okada , T. , Mizuno , Y. , Sibayama , S. , Hosokawa , M. and Miyashita , K. 2011 . Antiobesity effects of Undaria lipid capsules prepared with scallop phospholipids . J. Food Sci , doi: 10.1111/j.1750-3841.2010.01878.x
  • Okuda , H. and Han , L.-K. 2001 . Medicinal plant and its related metabolic modulators . Folia Pharmacol. Jpn. , 118 ( 5 ) : 347 – 351 .
  • Owuor , P. O. 2003 . “ Tea: Chemistry ” . In Encyclopaedia of Food Science and Nutrition, , 2nd ed. , Edited by: Benjamin , Caballero . 5743 – 5752 . London : Elsevier Science .
  • Padwal , R. , Li , S. K. and Lau , D. C. W. 2003 . Long-term pharmacotherapy for overweight and obesity: A systematic review and meta-analysis of randomized controlled trials . Int. J. Obesity. , 27 : 1437 – 1446 .
  • Padwal , R. S. and Majumdar , S. R. 2007 . Drug treatments for obesity: Orlistat, sibutramine, and rimonabant . Lancet , 369 : 71 – 77 .
  • Pereira , M. A. and Ludwig , D. S. 2001 . Dietary fiber and body-weight regulation: Observations and mechanisms . Pediatr. Clin. North Am. , 48 : 969 – 980 .
  • Picó , C. , Oliver , P. , Priego , T. , Sánchez , J. and Palou , A. 2006 . Functional foods and obesity: Strategies, effectiveness and safety . Rev. Esp. Obes. , 4 ( 3 ) : 156 – 174 .
  • Porcella , M. I. , Sánchez , G. , Vaudagna , S. R. , Zanelli , M. L. , Descalzo , A. M. , Meichtri , L. H. , Gallinger , M. M. and Lasta , J. A. 2001 . Soy protein isolate added to vacuum-packaged chorizos: Effect on drip loss, quality characteristics and stability during refrigerated storage . Meat Sci , 57 : 437 – 443 .
  • Puupponen-Pimiä , R. , Aura , A.-M. , Oksman-Caldentey , K.-M. , Myllärinen , P. , Saarela , M. , Mattila-Sandhom , T. and Poutanen , K. 2002 . Development of functional ingredients for gut health . Trends Food Sci. Tech. , 13 : 3 – 11 .
  • Quiles-Izquierdo , J. , Pérez-Rodrigo , C. , Serra-Majem , L. , Román , B. and Aranceta , J. 2008 . Obesity in Spain: Present situation and intervention strategies . Rev. Esp. Nutr. Comunitaria. , 14 ( 3 ) : 142 – 149 .
  • Reimer , R. A. , Pelletier , X. , Carabin , I. G. , Lyon , M. , Gahler , R. , Parnell , J. A. and Wood , S. 2010 . Increased plasma PYY levels following supplementation with the functional fiber PolyGlycopleX in healthy adults . Eur. J. Clin. Nutr. , 64 : 1186 – 1191 .
  • Rideout , T. C. , Harding , S. V. and Jones , P. J. H. 2010 . Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice . Mol. Nutr. Food Res , 54 : S7 – S13 .
  • Rincón-León , F. 2003 . “ Functional Foods ” . In Encyclopaedia of Food Science and Nutrition, , 2nd ed. , Edited by: Benjamin Caballero . 2827 – 2832 . London : Elsevier Science .
  • Rodríguez , R. , Jiménez , A. , Fernández-Bolaños , J. , Guillén , R. and Heredia , A. 2006 . Dietary fibre from vegetable products as a source of functional ingredients . Trends Food Sci. Tech. , 17 : 3 – 15 .
  • Rossi , E. A. , Cavallini , D. C. V. , Carlos , I. Z. , Vendramini , R. C. , Dâmaso , A. R. and de Valdez , G. F. 2008 . Intake of isoflavone-supplemented soy yogurt fermented with Enterococcus faecium lowers serum total cholesterol and non-HDL cholesterol of hypercholesterolemic rats . Eur. Food Res. Technol , 228 : 275 – 282 .
  • Ruiz-Rodriguez , A. , Marín , F. R. , Ocaña , A. and Soler-Rivas , C. 2008 . Effect of domestic processing on bioactive compounds . Phytochem. Rev. , 7 : 345 – 384 .
  • Saito , S. , Tomonobu , K. , Kudo , N. , Shiiba , D. , Hase , T. and Tokimitsu , I. 2006 . Serum retinol, α-tocopherol, and β-carotene levels are not altered by excess ingestion of diacylglycerol-containing plant sterol esters . Ann. Nutr. Metab. , 50 : 372 – 379 .
  • Sánchez-Zapata , E. , Fernández-López , J. , Sendra , E. , Sayas-Barberá , M. E. , Navarro , C. , Viuda-Martos , M. and Pérez-Alvarez , J. A. 2009 . Application of orange fibre for the control of oxidation in paté from yellowfin (Thunnus albacares) dark muscle (“sangacho”) . Alimentaria , 400 : 95
  • Sehat , N. , Yurawecz , M. P. , Roach , J. A. G. , Mossoba , M. M. , Kramer , J. K. G. and Ku , Y. 1998 . Silver-ion high-performance liquid chromatographic separation and identification of conjugated linoleic acid isomers . Lipids , 33 : 217 – 221 .
  • Sendra , E. , Fayos , P. , Lario , Y. , Fernández-López , J. , Sayas-Barberá , E. and Pérez-Alvarez , J. A. 2008 . Incorporation of citrus fibers in fermented milk containing probiotic bacteria . Food Microbiol , 25 ( 1 ) : 13 – 21 .
  • Serfert , Y. , Drusch , S. and Schawarz , K. 2009 . Chemical stabilisation of oils rich in long-chain polyunsaturated fatty acids during homogenization, microencapsulation and storage . Food Chem , 113 ( 4 ) : 1106 – 1112 .
  • Serrano , J. and Sánchez González , I. 2008 . Trends in functional foods against obesity: Functional ingredients, technologically modified foods and full diets . Rev. Esp. Nutr. Comunitaria. , 14 ( 3 ) : 193 – 200 .
  • Shai , I. , Schwarzfuchs , D. , Henkin , Y. , Shahar , D. R. , Witkow , S. , Greenberg , I. , Golan , R. , Fraser , D. , Bolotin , A. , Vardi , H. , Tangi-Rozental , O. , Zuk-Ramot , R. , Sarusi , B. , Brickner , D. , Schwartz , Z. , Sheiner , E. , Marko , R. , Katorza , E. , Thiery , J. , Fiedler , G. M. , Blüher , M. , Stumvoll , M. and Stampfer , M. J. 2008 . Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet . New Engl. J. Med. , 359 ( 3 ) : 229 – 241 .
  • Sherwood , N. E. and Story , M. 2003 . “ Obesity: Epidemiology ” . In Encyclopaedia of Food Science and Nutrition, , 2nd ed. , Edited by: Benjamin , Caballero . 4241 – 4246 . London : Elsevier Science .
  • Shi , H. , DiRienzo , D. and Zemel , M. B. 2001 . Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation energy-restricted aP2-agouti transgenic mice . FASEB J , 15 : 291 – 293 .
  • Shi , H. , Norman , A. W. , Okamura , W. H. , Sen , A. and Zemel , M. B. 2002 . 1,25-dihydroxyvitamin D3 inhibits uncoupling protein 2 expression in human adipocytes . FASEB J , 16 : 1808 – 1810 .
  • Shireman , R. 2003 . “ Essential fatty acids ” . In Encyclopaedia of Food Science and Nutrition, , 2nd ed. , Edited by: Benjamin , Caballero . 2169 – 2176 . London : Elsevier Science .
  • Silveira , M.-B. , Carraro , R. , Monereo , S. and Tébar , J. 2007 . Conjugated linoleic acid (CLA) and obesity . Public Health Nutr , 10 ( 10A ) : 1181 – 1186 .
  • Slavin , J. L. 2005 . Dietary fiber and body weight . Nutrition , 21 : 411 – 418 .
  • Smedman , A. and Vessby , B. 2001 . Conjugated linoleic acid supplementation in humans-metabolic effects . J. Nutr. , 36 : 773 – 781 .
  • Smith , T. H. , Sim-Selley , L. J. and Selley , D. E. 2010 . Cannabinoid CB1 receptor-interacting proteins: Novel targets for central nervous system drug discovery? . Brit. J. Pharmacol. , 160 : 454 – 466 .
  • Stevens , J. , Ahn , K. , Juhaeri , Houston , D. , Steffan , L. and Couper , D. 2002 . Dietary fiber intake and glycemic index and incidence of diabetes in African-American and white adults: The ARIC study . Diabetes Care , 25 : 1715 – 1721 .
  • Sun , X. and Zemel , M. B. 2004 . Role of uncoupling protein 2 (UCP2) expression and 1α, 25-dihydroxyvitamin D3 in modulating adipocyte apoptosis . FASEB J , 18 ( 12 ) : 1430 – 1432 .
  • Suzuki , K. , Konno , R. , Shimizu , T. , Nagashima , T. and Kimura , A. 2007 . A fermentation product of phytosterol including campestenone reduces body fat storage and body weight gain in mice . J. Nutr. Sci. Vitaminol. , 53 : 63 – 67 .
  • Takeshita , M. , Saito , S. , Moriwaki , J. , Takase , N. , Shiiba , D. , Kudo , N. , Nakajima , Y. and Tokimitsu , I. 2007 . Effects of dietary diacylglycerol oil containing phytosterols in mayonnaise on abdominal fat and blood cholesterol levels in Japanese men . Jpn. Pharmacol. Ther. , 39 : 973 – 987 .
  • Thane , C. W. , Stephen , A. M. and Jebb , S. A. 2007 . Whole grains and adiposity: Little association among British adults . Eur. J. Clin. Nutr. , 63 : 229 – 237 .
  • Thom , E. , Wadstein , J. and Gudmundson , O. 2001 . Conjugated linoleic acid reduces body fat in healthy exercising humans . J. Int. Med. Res. , 29 : 392 – 396 .
  • Tsuda , T. 2008 . Regulation of adipocyte function by anthocyanins; possibility of preventing the metabolic syndrome . J. Agric. Food Chem. , 56 : 642 – 646 .
  • Tsuda , T. , Horio , F. , Uchida , K. , Aoki , H. and Osawa , T. 2003 . Dietary cyanidin 3-O-β-D-glucoside-rich purple corn color prevents obesity and ameliorated hyperglycemia in mice . J. Nutr. , 133 : 2125 – 2130 .
  • Tsuda , T. , Ueno , Y. , Kojo , H. , Yoshikawa , T. and Osawa , T. 2005 . Gene expression profile of isolated rat adipocytes treated with anthocyanins . Biochim. Biophys. Acta. , 1733 : 137 – 147 .
  • Tsunoda , N. , Ikemoto , S. , Takahashi , M. , Maruyama , K. , Watanabe , H. , Goto , N. and Ezaki , O. 1998 . High-monounsaturated fat diet-induced obesity and diabetes in C57BL/6J mice . Metabolism , 47 : 724 – 730 .
  • Tsuzuki , T. , Kawakami , Y. , Nakagawa , K. and Miyazawa , T. 2006 . Conjugated docosahexaenoic acid inhibits lipid accumulation in rats . J. Nutr. Biochem. , 17 ( 8 ) : 518 – 524 .
  • Tsuzuki , T. , Kawakami , Y. , Suzuki , Y. , Abe , R. , Nakagawa , K. and Miyazawa , T. 2005 . Intake of conjugated eicosapentaenoic acid suppresses lipid accumulation in liver and epididymal adipose tissue in rats . Lipids , 40 ( 11 ) : 1117 – 1123 .
  • Ubbink , J. and Krüger , J. 2006 . Physical approaches for the delivery of active ingredients in foods . Trends Food Sci. Tech. , 17 : 244 – 254 .
  • van Boekel , M , Fogliano , V. , Pellegrini , N. , Stanton , C. , Scholz , G. , Lalljie , S. , Somoza , V. , Knorr , D. , Jasti , P. R. and Eisenbrand , G. 2010 . A review on the beneficial aspects of food processing . Mol. Nutr. Food Res. , 54 : 1215 – 1247 .
  • Van Gaal , L. F. , Rissanen , A. M. , Scheen , A. J. , Ziegler , O. and Rössner , S. 2005 . Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study . Lancet , 365 : 1389 – 1397 .
  • Velasquez , M. T. and Bhathena , S. J. 2007 . Role of dietary soy protein in obesity . Int. J. Med. Sci. , 4 : 72 – 82 .
  • Vincent , R. P. and le Roux , C. W. 2007 . New agents in development for the management of obesity . Int. J. Clin. Pract. , 61 ( 12 ) : 2103 – 2112 .
  • Viuda-Martos , M. , López-Marcos , M. C. , Fernández-López , J. , Sendra , E. , López-Vargas , J. H. and Pérez-Álvarez , J. A. 2010a . Role of fiber in cardiovascular diseases: A review . Compr. Rev. Food. Sci. Food Saf. , 9 : 240 – 258 .
  • Viuda-Martos , M. , Ruiz-Navajas , Y. , Fernández-López , J. and Pérez-Álvarez , J. A. 2009 . Effect of adding citrus waste water, thyme and oregano essential oil on the chemical, physical and sensory characteristics of a bologna sausage . Innov. Food Sci. Emerg. , 10 : 655 – 660 .
  • Viuda-Martos , M. , Ruiz-Navajas , Y. , Fernández-López , J. and Pérez-Álvarez , J. A. 2010b . Effect of adding citrus fibre washing water and rosemary essential oil on the quality characteristics of a bologna sausage . LWT-Food Sci. Technol. , 43 : 958 – 963 .
  • Vögler , O. , López-Bellan , A. , Alemany , R. , Tofé , S. , González , M. , Quevedo , J. , Pereg , V. , Barceló , J. and Escribá , P. V. 2008 . Structure-effect relation of C18 long-chain fatty acids in the reduction of body weight in rats . Int. J. Obesity. , 32 : 464 – 473 .
  • Wachtel-Galor , S. , Wing Wong , K. and Benzie , I. F. F. 2008 . The effect of cooking on Brassica vegetables . Food Chem , 110 : 706 – 710 .
  • Wang , Y. , Jacome-Sosa , M. M. , Ruth , M. R. , Goruk , S. D. , Reaney , M. J. , Glimm , D. R. , Wright , D. C. , Vine , D. F. , Field , C. J. and Proctor , S. D. 2009 . Trans-11 vaccenic acid reduces hepatic lipogenesis and chylomicron secretion in JCR: LA-cp rats . J. Nutr , 139 : 2049 – 2054 .
  • Wang , Y. , Jacome-Sosa , M. M. , Vine , D. F. and Proctor , S. D. 2010 . Beneficial effects of vaccenic acid on postprandial lipid metabolism and dyslipidemia: Impact of natural trans-fats to improve CVD risk . Lipid Technol , 22 ( 5 ) : 103 – 106 .
  • Wang , Y. , Lu , J. , Ruth , M. R. , Goruk , S. D. , Reaney , M. J. , Glimm , D. R. , Vine , D. F. , Field , C. J. and Proctor , S. D. 2008 . Trans-11 vaccenic acid dietary supplementation induces hypolipidemic effects in JCR: LA-cp rats . J. Nutr , 138 : 2117 – 2122 .
  • Westerterp-Plantenga , M. S. , Lejeune , M. P. and Kovacs , E. M. 2005 . Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation . Obes. Res. , 13 : 1195 – 1204 .
  • WHO, World Health Organization . 1998 . Obesity: Preventing and managing the global epidemic. WHO technical report series 894 . Geneva ,
  • WHO, World Health Organization . 2003 . Diet, nutrition and the prevention of chronic diseases. WHO technical report series 916 . Geneva ,
  • WHO, World Health Organization . 2009 . Available from http://www.who.int/healthinfo/global_burden_disease/global_health_risks/en/index.html
  • WHO, World Health Organization . 2010 . Available from http://www.who.int/features/factfiles/obesity/facts/en/index9.html. Consulted January 11th, 2011
  • Willumsen , N. , Hexeberg , S. , Skorve , J. , Lundquist , M. and Berge , R. K. 1993 . Docosahexaenoic acid shows no triglyceride-lowering effects but increases the peroxisomal fatty acid oxidation in liver of rats . J. Lipid Res. , 34 : 13 – 22 .
  • Wolfram , S. , Wang , Y. and Thielecke , F. 2006 . Anti-obesity effects of green tea: From bedside to bench . Mol. Nutr. Food Res. , 50 : 176 – 187 .
  • Wu , J. , Oka , J. , Higuchi , M. , Tabata , I. , Toda , T. , Fujioka , M. , Fuku , N. , Teramoto , T. , Okuhira , T. , Ueno , T. , Uchiyama , S. , Urata , K. , Yamada , K. and Ishimi , Y. 2006 . Cooperative effects of isoflavones and exercise on bone and lipid metabolism in postmenopausal Japanese women: A randomized placebo-controlled trial . Metabolism , 55 : 423 – 433 .
  • Wu , C.-H. , Yang , M.-Y. , Chan , K.-C. , Chung , P.-J. , Ou , T.-T. and Wang , C.-J. 2010 . Improvement in high-fat diet-induced obesity and body fat accumulation by a Nelumbo nucifera leaf flavonoid-rich extract in mice . J. Agric. Food Chem , 58 : 7075 – 7081 .
  • Yep , Y. L. , Li , D. , Mann , N. J. , Bode , O. and Sinclair , A. J. 2002 . Bread enriched with microencapsulated tuna oil increases plasma docosahexaenoic acid and total omega-3 oils in humans . Asia Pac. J. Clin. Nutr. , 11 ( 4 ) : 285 – 291 .
  • Zemel , M. B. 2002 . Regulation of adiposity and obesity risk by dietary calcium: Mechanisms and implications . J. Am. Coll. Nutr. , 21 ( 2 ) : 146S – 151S .
  • Zemel , M. B. , Shi , H. , Greer , B. , DiRienzo , D. and Zemel , P. C. 2000 . Regulation of adiposity by dietary calcium . FASEB J , 14 : 1132 – 1138 .
  • Zemel , M. B. 2003 . Mechanisms of dairy modulation of adiposity . J. Nutr. , 133 : 252S – 256S .
  • Zemel , M. B. 2005 . The role of dairy foods in weight management . J. Am. Coll. Nutr. , 24 ( 6 ) : 537S – 546S .
  • Zhao , H. L. , Harding , S. V. , Marinangeli , C. P. F. , Kim , Y. S. and Jones , P. J. H. 2008 . Hypocholesterolemic and anti-obesity effects of saponins from Platycodon grandiflorum in hamsters fed atherogenic diets . J. Food Sci , 73 ( 8 ) : 195 – 200 .
  • Zheng , G. , Sayama , K. , Okubo , T. , Juneja , L. R. and Oguni , I. 2004 . Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice . In Vivo , 18 : 55 – 62 .

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