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Original Articles

Antidiabetic Potential of Commonly Consumed Legumes: A Review

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REFERENCES

  • Adeparusi , E. O. 2001 . Effect of processing on the nutrients and anti-nutrients of lima bean (Phaseolus lunatus L.) flour . Nahrung/Food. , 45 ( 2 ) : 94 – 96 .
  • Adsule , R. N. , Lawande , K. M. and Kadam , S. S. 1989 . “ Pea ” . In Handbook of World Food Legumes: Nutritional Chemistry, Processing Technology and Utilization , Edited by: Salunkhe , D. K. and Kadam , S. S. 215 – 251 . Boca Raton , FL : CRC Press .
  • Akhtar , M. S. , Asim , A. H. and Wolever , T. M. S. 1987 . Blood glucose responses to traditional Pakistani dishes taken by normal and diabetic subjects . Nutr. Res. , 7 ( 7 ) : 697 – 706 .
  • Akinmutimi , A. H. and Ezea , J. 2006 . Effect of graded levels of toasted lima bean (Phaseolus lunatus) meal in weaner rabbit diets . Pakistan J. Nutr. , 5 ( 4 ) : 368 – 372 .
  • American Diabetes Assocation . n.d. . Available from http://www.diabetes.org/nutrition-and-recipes/nutrition/foodpyramid.jsp (accessed April 8, 2009)
  • Almeida Costa , G. E. , Queiroz-Monici , K. D. S. , Reis , S. M. P. M. and Oliveira , A. C. 2006 . Chemical composition, dietary fibre and resistant starch contents of raw and cooked pea, common bean, chickpea and lentil legumes . Food Chem. , 94 ( 3 ) : 327 – 330 .
  • Alzorriz , M. A. Z. and Hernandez , J. A. M. 1999 . Hypercholesterolemia: Possible beneficial role of dietary chickpea Cicer arietinum L. var. macrocarpum or pharmacological treatment with b3-adrenergic agonist . Anales Real Acad. Farmacia. , 65 ( 2 ) : 327 – 349 .
  • Amalraj , T. and Ignacimuthu , S. 1998 . Hypoglycemic activity of Cajanus cajan (seeds) in mice . Indian J. Exp. Biol. , 36 : 1032 – 1033 .
  • Amarteifio , J. O. , Munthali , D. C. , Karikari , S. K. and Morake , T. K. 2002 . The composition of pigeon peas (Cajanus cajan (L.) Millsp.) grown in Botswana . Plant Foods Hum. Nutr. , 57 : 173 – 177 .
  • Anderson , J. W. , Hanna , T. J. , Peng , X. and Kryscio , R. J. 2000 . Whole grain foods and heart disease risk . J. Am. Coll. Nutr. , 19 ( 90003 ) : 291S – 299S .
  • Anderson , J. W. , Johnstone , B. M. and Cook-Newell , M. E. 1995 . Meta-analysis of the effects of soy protein intake on serum lipids . N. Engl. J. Med. , 333 : 276 – 82 .
  • Anisha , G. S. and Prema , P. 2008 . Reduction of non-digestible oligosaccharides in horse gram and green gram flours using crude α-galactosidase from Streptomyces griseoloalbus . Food Chem. , 106 ( 3 ) : 1175 – 1179 .
  • Anosike , C. A. , Obidoa , O. and Ezeanyika , L. U. S. 2008 . Beneficial effects of soybean diet on serum marker enzymes, lipid profile and relative organ weights of Wistar rats . Pakistan J. Nutr. , 7 ( 6 ) : 817 – 822 .
  • Boby , R. G. and Leelamma , S. 2003 . Blackgram fiber (Phaseolus mungo): Mechanism of hypoglycemic action . Plant Foods Hum. Nutr. , 58 : 7 – 13 .
  • Bonilla , S. , Noel-Suberville , C. , Higueret , P. , Puy Portillo , M. , Macarulla , M. T. , Martinez , A. and Garcin , H. 1998 . Inclusion of a legume in a saturated fat-rich diet affects the cholesterol status but not the expression of triiodothyronine and retinoic acid receptors in rat liver . Ann. Nutr. Metab. , 42 : 297 – 303 .
  • Brand , J. C. , Snow , B. J. , Nabhan , G. P. and Truswell , A. S. 1990 . Plasma glucose and insulin responses to traditional Pima Indian meals . Am. J. Clin. Nutr. , 5 ( I ) : 416 – 420 .
  • Brand-Miller , J. , Hayne , S. , Petocz , P. and Colagiuri , S. 2003 . Low–glycemic index diets in the management of diabetes a meta-analysis of randomized controlled trials . Diabetes Care. , 26 ( 8 ) : 2261 – 2267 .
  • Bravo , L. , Siddhuraju , P. and Saura-Calixto , F. 1999 . Composition of underexploited Indian pulses: Comparison with common legumes . Food Chem. , 64 : 185 – 192 .
  • Burcelin , R. , Rolland , E. , Dolci , W. , Germain , S. , Carrel , V. and Thorens , B. 1999 . Encapsulated, genetically engineered cells, secreting glucagon-like peptide-1 for the treatment of non-insulin-dependent diabetes mellitus . Ann. N Y Acad. Sci. , 875 : 277 – 285 .
  • Canadian Diabetes Association . 2008 . Available from http://www.diabetes.ca/files/Diabetes_GL_FINAL2_CPG03.pdf (accessed April 8, 2009)
  • Carman , K . 1996 . Some physical properties of lentil seeds . J. Agric. Engng. Res. , 63 : 87 – 92 .
  • Celleno , L. , Tolaini , M. V. , D’Amore , A. , Perricone , N. V. and Preuss , H. G. 2007 . A dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women . Int. J. Med. Sci. , 4 ( 1 ) : 45 – 52 .
  • Cerović , A. , Miletić , I. , Konić-Ristić , A. , Baralić , I. , Djordjević , B. , Djuricić , I. and Radusinović , M. 2006 . The dry plant extract of common bean seed (Phaseoli vulgari pericarpium) does not have an affect on postprandial glycemia in healthy human subject . Bosn. J. Basic Med. Sci. , 6 ( 3 ) : 28 – 33 .
  • Chau , C. F. and Cheung , P. C. K. 1999 . Effects of the physico-chemical properties of three legume fibers on cholesterol absorption in hamsters . Nutr. Res. , 19 ( 2 ) : 257 – 265 .
  • Chau , C. F. , Cheung , P. C. K. and Wong , Y. S. 1998 . Hypocholesterolemic effects of protein concentrates from three Chinese indigenous legume seeds . J. Agric. Food Chem. , 46 ( 9 ) : 3698 – 3701 .
  • Chen , H. , Li-jun , L. , Jian-jun , Z. , Boa , X. and Rui , L. 2010 . Effect of soybean oligosaccharides on blood lipid, glucose levels and antioxidant enzymes activity in high fat rats . Food Chem. , 119 : 1633 – 1636 .
  • Clark , C. M. and Lee , D. A. 1995 . Prevention and treatment of the complications of diabetes mellitus . N Engl. J. Med. , 332 ( 18 ) : 1210 – 1217 .
  • Costa , N. M. B. , Walker , A. F. and Low , A. G. 1993 . The effect of graded inclusion of baked beans (Phaseolus vulgaris) on plasma and liver lipids in hypercholesterolemic pigs given a Western- type diet . Br. J. Nutr. , 70 ( 2 ) : 515 – 524 .
  • Cunningham , J. , Leffell , M. , Mearkle , P. and Harmatz , P. 1995 . Elevated plasma ceruloplasmin in insulin-dependent diabetes mellitus: Evidence for increased oxidative stress as a variable complication . Metabolism. , 44 ( 8 ) : 996 – 999 .
  • Dabai , F. D. , Walker , A. F. , Sambrook , I. E. , Welch , V. A. and Owen , R. W. 1996 . Comparative effects on blood lipids and faecal steroids of five legume species incorporated into a semi-purified, hypercholesterolaemic rat diet . Br. J. Nutr. , 75 : 557 – 551 .
  • David , M. N. 1993 . Long-term complications of diabetes mellitus . N Engl. J. Med. , 328 ( 23 ) : 1676 – 1685 .
  • Devi , K. S. and Kurup , P. A. 1970 . Effects of certain Indian pulses on the serum, liver and aortic lipid levels in rats fed a hypercholesterolaemic diet . Atherosclerosis. , 11 ( 3 ) : 479 – 484 .
  • Devi , K. S. and Kurup , P. A. 1972 . Hypolipidaemic activity of Phaseolus mungo (blackgram) in rats fed a high-fat-high-cholesterol diet. Isolation of a protein and polysaccharide fraction . Atherosclerosis. , 15 ( 2 ) : 223 – 230 .
  • Devi , K. S. and Kurup , P. A. 1973 . Hypolipidaemic activity of the protein and polysaccharide fraction from Phaseolus mungo (blackgram) in rats fed a high-fat-high-cholesterol diet . Atherosclerosis , 18 ( 3 ) : 389 – 397 .
  • Diabetes Prevention Program Research Group . 2002 . Reduction in the incidence of Type 2 diabetes with lifestyle intervention or metformin . N Engl. J. Med. , 346 : 393 – 403 .
  • Dictionary of Chinese . 1977 . Dictionary of Chinese Crude Drugs (in Chinese) , 1090 Shanghai : Chiang Su New Medical College, Shanghai Scientific Technologic Publisher .
  • Dilawari , J. B. , Kamath , P. S. and Batta , R. P. 1981 . Reduction of postprandial plasma glucose by Bengal gram dal (Cicer arietinum) and rajmah (Phaseolus vulgaris) . Am. J. Clin. Nutr. , 34 : 2450 – 2453 .
  • Duane , W. C. 1997 . Effects of legume consumption on serum cholesterol, biliary lipids, and sterol metabolism in humans . J. Zipid Hps. , 38 : 1120 – 1128 .
  • Duranti , M. 2006 . Grain legume proteins and nutraceutical properties . Fitoterapia. , 77 ( 2 ) : 67 – 82 .
  • Duranti , M. and Gius , C. 1997 . Legume seeds: Protein content and nutritional value . Field Crops Res. , 53 : 31 – 45 .
  • Eriksson , K.-F. and Lindgiirde , E. 1991 . Prevention of Type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise . Diabetologia. , 34 : 891 – 898 .
  • Esposito Avella , M. , Diaz , A. , de Gracia , I. , de Tello , R. and Gupta , M. P. 1991 . Evaluation of traditional medicine: Effects of Cajanus cajan L. and of Cassia fistula L. on carbohydrate metabolism in mice . Revista Med. Panama. , 16 : 39 – 45 .
  • Fatima , S. and Kapoor , R. 2006 . In vivo and in vitro glycemic effects of certain legumes . J. Food Sci. Technol. , 43 ( 3 ) : 263 – 266 .
  • Food and Agriculture Organization (FAO) . 1993 . Production Yearbook, 1992. Vol. 26 , Rome : Food and Agriculture Organization .
  • Frllhbeck , G. , Monreal , I. and Santidri , S. 1997 . Hormonal implications of the hypocholesterolemic effect of intake of field beans (Vicia faba L.) by young men with hypercholesterolemia . Am. J. Clin. Nutr. , 66 : 1452 – 1460 .
  • Fukushimaa , M. , Ohashia , T. , Kojimaa , M. , Ohbab , K. , Shimizub , H. , Sonoyamac , K. and Nakanoa , M. 2001 . Low density lipoprotein receptor mRNA in rat liver is affected by resistant starch of beans . Lipids. , 36 : 129 – 134 .
  • Gatchalian-Yee , M. , Arimura , Y. , Ochiai , E. , Yamada , K. and Sugano , M. 1997 . Soybean protein lowers serum cholesterol levels in hamsters: Effect of debittered undigested fraction . Nutrition. , 13 : (7):633 – 639 .
  • Goñi , I. and Valentín-Gamazo , C. 2003 . Chickpea flour ingredient slows glycemic response to pasta in healthy volunteers . Food Chem. , 81 : 511 – 515 .
  • Han , K.-H. , Fukushima , M. , Kato , T. , Kojima , M. , Ohba , K. , Shimada , K. , Sekikawa , M. and Nakano , M. 2003a . Enzyme-resistant fractions of beans lowered serum cholesterol and increased sterol excretions and hepatic mRNA levels in rats . Lipids. , 38 : 919 – 924 .
  • Han , K.-H. , Fukushima , M , Shimizu , K. , Kojima , M. , Ohba , K. , Tanaka , A. , Shimada , K.-I. , Sekikawa , M. and Nakano , M. 2003b . Resistant starches of beans reduce the serum cholesterol concentration in rats . J. Nutr. Sci. Vitaminol. , 49 ( 4 ) : 281 – 286 .
  • Han , K.-H. , Iijuka , M , Shimada , K.-I. , Sekikawa , M. , Kuramochi , K. , Ohba , K. , Ruvini , L. , Chiji , H. and Fukushima , M. 2005 . Adzuki resistant starch lowered serum cholesterol and hepatic 3-hydroxy-3-methylglutaryl-CoA mRNA levels and increased hepatic LDL-receptor and cholesterol 7a-hydroxylase mRNA levels in rats fed a cholesterol diet . Br. J. Nutr. , 94 : 902 – 908 .
  • Hermansen , K. , Søndergaard , M. , Høie , L. , Carstensen , M. and Brock , B. 2001 . Beneficial effects of a soy-based dietary supplement on lipid levels and cardiovascular risk markers in type 2 diabetic subjects . Diabetes Care. , 24 ( 2 ) : 228 – 233 .
  • Hoorfar , J. , Scott , S. W. and Cloãoetier , H. E. 1991 . Dietary plant materials and development of diabetes in the BB rat . J. Nutr. , 121 : 908 – 916 .
  • Indira , M. and Kurup , P. A. 1982 . Effect of blackgram fibre on ethanol-induced hyperlipidemia in rats . Atherosclerosis. , 241 ( 2–3 ) : 241 – 246 .
  • Indira , M. and Kurup , P. A. 1989 . Effects of neutral detergent fiber from blackgram (Phaseolus mungo) in rats and rabbits . J. Nutr. , 119 ( 9 ) : 1246 – 1251 .
  • Itoh , T. , Kita , N. , Kurokawa , Y. , Kobayashi , M. , Horio , F. and Furuichi , Y. 2004 . Suppressive effect of a hot water extract of adzuki beans (Vigna angularis) on hyperglycaemia after sucrose loading in mice and diabetic rats . Biosci. Biotechnol. Biochem. , 68 ( 12 ) : 2421 – 2426 .
  • Jaiswal , D. , Rai , P. K. , Kumar , A. and Watal , G. 2008 . Study of glycemic profile of Cajanus cajan leaves in experimental rats . Indian J. Clin. Biochem. , 23 ( 2 ) : 167 – 170 .
  • Jang , Y. , Lee , J. H. , Kim , O. Y. , Park , H. Y. and Lee , S. Y. 2001 . Consumption of whole grain and legume powder reduces insulin demand, lipid peroxidation, and plasma homocysteine concentrations in patients with coronary artery disease . Arterioscler. Thromb. Vasc. Biol. , 21 : 2065
  • Jaya , T. V. , Mengheri , E. , Scarino , M. L. , Vignolini , F. and Spadoni , M. A. 1981 . Evaluation of hypocholesterolemic effect of faba bean protein concentrate on rats fed a high-fat-high-cholesterol diet . Nutr. Rep. Int. , 23 ( 1 ) : 55 – 69 .
  • Jaya , T. V. and Venkataraman , L. V. 1979 . Germinated legumes and their influence on liver and serum cholesterol levels in rats Influence of different components of chickpea and green gram on tissue cholesterol levels in rats . Nutr. Rep. Int. , 20 ( 3 ) : 383 – 392 .
  • Jayagopal , V. , Albertazzi , P. , Kilpatrick , E. S. , Howarth , E. M. , Jennings , P. E. , Hepburn , D. A. and Atkin , S. L. 2002 . Beneficial effects of soy phytoestrogen intake in postmenopausal women with type 2 diabetes . Diabetes Care. , 25 : 1709 – 1714 .
  • Jayakumari , N. and Kurup , P. A. 1979 . Dietary fiber and cholesterol metabolism in rats fed a high cholesterol diet . Atherosclerosis. , 33 ( 1 ) : 41 – 47 .
  • Jenkins , D. J. A. , Thorne , M. J. , Camelon , K. , Jenkins , A. , Rao , A. V. , Taylor , R. H. , Thompson , L. U. , Kalmusky , J. , Reichert , R. and Francis , T. 1982 . Effect of processing on digestibility and the blood glucose response: A study of lentils . Am. J. Clin. Nutr. , 36 : 1093 – 1101 .
  • Jenkins , D. J. A. , Wolever , T. M. S. , Taylor , R. H. , Barker , H. , Fielden , H. , Baldwin , J. M. , Bowling , A. C. , Newman , H. C. , Jenkins , A. L. and Goff , D. V. 1981 . Glycemic index of foods: A physiological basis for carbohydrate exchange . Am. J. Clin. Nutr. , 34 : 362 – 366 .
  • Jishu , Q. , Xuezhe , Y. , Makoto , T. and Takemichi , K. 2004 . The hypoglycemic effects of soybean hypocotyl extract in diabetic rats and their mechanism . Yingyang Xuebao. , 26 ( 3 ) : 207 – 210 .
  • Jishu , Q. , Xuezhe , Y. , Mingzhu , L. , Minghua , S. and Chunmei , P. 2005 . Inhibitive effects of soybean isoflavones on α-glucosidase . Zhongcaoyao , 36 ( 9 ) : 1377 – 1379 .
  • Juliano , B. O. , Perez , C. M. , Komindr , S. and Banphotkasem , S. 1989 . Properties of Thai cooked rice and noodles differing in glycemic index in noninsulin-dependent diabetics . Plant Foods Hum. Nutr. , 39 : 369 – 374 .
  • Kabir , M. , Guerre-Millo , M. , Laromiguiere , M. , Slama , G. and Rizkalla , S. W. 2000 . Negative regulation of leptin by chronic high glycemic index starch diet . Metabolism. , 49 : 764 – 769 .
  • Kabir , M. , Rizkalla , S. W. , Champ , M. , Luo , J. , Boillot , J. , Bruzzo , F. and Slama , G. 1998a . Dietary amylose-amylopectin starch content affects glucose and lipid metabolism in adipocytes of normal and diabetic rats . J. Nutr. , 128 : 35 – 43 .
  • Kabir , M. , Rizkalla , S. W. , Quignard-Boulange , A. , Guerre-Millo , M. , Boillot , J. , Ardouin , B. , Luo , J. and Slama , G. A. 1998b . High glycemic index starch diet affects lipid storage-related enzymes in normal and to a lesser extent in diabetic rats . J. Nutr. , 128 : 1878 – 1883 .
  • Kang , M.-J. , Kim , J.-I. , Yoon , S.-Y. and Kim , J. C. 2006 . Pinitol from soybeans reduces postprandial blood glucose in patients with type 2 diabetes mellitus . J. Med. Food , 9 ( 2 ) : 182 – 186 .
  • Kaushik , G. , Satya , S. , Khandelwal , R. K. and Naik , S. N. 2010 . Commonly consumed Indian plant food materials in the management of diabetes mellitus . Diabetes Metab Syn Clin Res Rev. , 4 ( 1 ) : 21 – 40 .
  • Kazumi , Y. , Masato , N. and Yutaka , M. 2008 . Blood glucose regulation by a soybean isoflavone, genistein: Studies in cultured cells and type 2 diabetic mice . Daizu Tanpakushitsu Kenkyu , 11 : 121 – 126 .
  • Kennedy , A. R. 1995 . The evidence for soybean products as cancer preventative agents . J. Nutr. , 125 : S733 – S743 .
  • Khaleeva , L. D. , Maloshtan , L. N. and Sytnik , A. G. 1987 . Comparative assessment of hypoglycemic activity of the grass complex from kidney bean grass and chlorpropamide in experimental diabetes . Problemy Endokrinolog , 33 ( 2 ) : 69 – 71 .
  • Kingman , S. M. , Walker , A. F. , Low , A. G. , Sambrook , I. E. , Owen , R. W. and Cole , T. J. 1993s . Comparative effects of four legume species on plasma lipids and faecal steroid excretion in hypercholesterolaemic pigs . Br. J. Nutr , 69 : 409 – 421 .
  • Kojima , M. , Nishi , S. , Yamashita , S. , Saito , Y. and Maeda , R. 2006a . Antioxidative effect and liver protective action of Adzuki polyphenol . Nippon Shokuhin Kagaku Kogaku Kaishi. , 53 : 386 – 392 .
  • Kojima , M. , Nishi , S. , Yamashita , S. , Saito , Y. and Maeda , R. 2006b . Smaller increase in serum cholesterol level in rats fed an ethanol extract of adzuki bean seeds . J. Jpn Soc. Food Sci. Technol. , 53 ( 7 ) : 380 – 385 .
  • Kottai , M. A. , Sethupathy , S. , Manavalan , R. and Karar , P. K. 2005 . Hypolipidemic effect of methanolic extract of Dolichos biflorus Linn. in high fat diet fed rats . Indian J. Exp. Biol. , 43 ( 6 ) : 522 – 525 .
  • Kottai , M. A. , Sethupathy , S. , Manavalan , R. and Karar , P. K. 2006 . Antioxidant potential of methanolic extract of Dolichos biflorus Linn in high fat diet fed rabbits . Indian J. Pharmacol. , 38 ( 2 ) : 131 – 132 .
  • Lee , S.-H. and Park , I.-S. 2000 . Effects of soybean diet on the β cells in the streptozotocin treated rats for induction of diabetes . Diabetes Res. Clin. Pract. , 47 : 1 – 13 .
  • Lerer-Metzger , M. , Rizkalla , S. W. , Luo , J. , Champ , M. , Kabir , M. , Bruzzo , F. , Bornet , F. and Slama , G. 1996 . Effects of long-term low-glycaemic index starchy food on plasma glucose and lipid concentrations and adipose tissue cellularity in normal and diabetic rats . Br. J. Nutr , 75 : 723 – 732 .
  • Lipinski , B. 2001 . Pathophysiology of oxidative stress in diabetes mellitus . J. Diabetes Complications. , 15 : 203 – 210 .
  • Lovati , M. R. , Manzoni , C. , Corsini , A. , Granata , A. , Frattini , R. , Fumagalli , R. and Sirtori , C. R. 1992 . Low density lipoprotein receptor activity is modulated by soybean globulins in cell culture . J. Nutr. , 122 : 1971 – 1978 .
  • Luo , Q. F. , Sun , L. , Si , J. Y. , Chen , D. H. and Du , G. H. 2008 . Hypocholesterolemic effect of stilbene extract from Cajanus cajan L. on serum and hepatic lipid in diet-induced hyperlipidemic mice. . Yao Xue Xue Bao. , 43 ( 2 ) : 145 – 149 .
  • Macarulla , M. T. , Medina , C. , AraÂnzazu De Diego , M. , ChaÂvarri , M. , AÂ ngeles Zulet , M. , MartõÂnez , J. A. , NoÈel-Suberville , C. , Higueret , P. and Portillo , M. P. 2001 . Effects of the whole seed and a protein isolate of faba bean (Vicia faba) on the cholesterol metabolism of hypercholesterolaemic rats . Br. J. Nutr , 85 : 607 – 614 .
  • Madar , Z. and Stark , A. H. 2002 . New legume sources as therapeutic agents . Br. J. Nutr , 88 ( 3 ) : S287 – S292 .
  • Malik , S. , Jawaid , I. and Siddiqui , M. 1985 . Effect of Bengal gram (Cicer arietinum) fractions on fructose-induced hyperlipidemia . IRCS Med. Sci. , 13 ( 6 ) : 487 – 488 .
  • Mallare , J. T. , Karabell , A. H. , Velasquez-Mieyer , P. , Stender , S. R. S. and Christensen , M. L. 2005 . Current and future treatment of metabolic syndrome and Type 2 diabetes in children and adolescents . Diabetes Spectr. , 18 ( 4 ) : 221 – 225 .
  • Mani , U. V. , Pradhan , S. N. , Mehta , N. C. , Thakur , D. M. , Iyer , U. and Mani , I. 1992 . Glycaemic index of conventional carbohydrate meals . Br. J. Nutr , 68 : 445 – 450 .
  • Martinezm , J. A. and Macarulla , T. 1992 . Nutritional outcome and immunocompetence in mice fed on a diet containing raw field beans (Vicia faba, var. minor) as the source of protein . Br. J. Nutr , 68 : 493 – 503 .
  • Martins , J. M. , Riottot , M. , Abreu , M. C. , Lanc , M. J. , Viegas-Crespo , A. M. , Almeida , J. A. , Freire , J. B. and Bento , O. P. 2004 . Dietary raw peas (Pisum sativum L.) reduce plasma total and LDL cholesterol and hepatic esterified cholesterol in intact and ileorectal anastomosed pigs fed cholesterol-rich diets . J. Nutr , 134 : 3305 – 3312 .
  • Maruyama , C. , Araki , R. , Kawamura , M. , Kondo , N. , Kigawa , M. , Kawai , Y. , Takanami , Y. , Miyashita , K. and Shimomitsu , T. 2008 . Azuki bean juice lowers serum triglyceride concentrations in healthy young women . J. Clin. Biochem. Nutr. , 43 ( 1 ) : 19 – 25 .
  • Mateos-Aparicio , I. , Cuenca , A. R. , Villanueva-Suárez , M. J. and Zapata-Revilla , M. A. 2008 . Soybean, a promising health source . Nutr. Hosp. , 23 ( 4 ) : 305 – 312 .
  • Mathur , K. S. , Khan , M. A. and Sharma , R. D. 1968 . Hypocholesterolaemic effect of Bengal gram: A long-term study in man . BMJ. , 1 : 30 – 31 .
  • Mathur , K. S. , Singhal , S. S. and Sharma , R. D. 1964 . Effect of Bengal gram on experimentally induced high levels of cholesterol in tissues and serum in albino rats . J. Nutr. , 84 : 201 – 204 .
  • Mayilvaganan , M. , Singh , S. P. and Johari , R. P. 2004 . Hypocholesterolemic effect of protein prepared from Phaseolus aconitifolius (Jacq.) . Indian J. Exp. Biol. , 42 ( 9 ) : 904 – 908 .
  • Memisogullari , R. , Taysi , S. , Bakan , E. and Capoglu , I. 2003 . Antioxidant status and lipid peroxidation in type II diabetes mellitus . Cell Biochem. Funct. , 21 ( 3 ) : 291 – 296 .
  • Mengheri , E. , Scarino , M. L. , Vignolini , F. and Spadoni , M. A. 1985 . Modifications in plasma cholesterol and apolipoproteins of hypercholesterolaemic rats induced by ethanol-soluble factors of Vicia faba . Br. J. Nutr , 53 : 223 – 232 .
  • Menon , P. V. G. and Kurup , P. A. 1974 . Hypolipidaemic action of the polysaccharide from Phaseolus mungo (Blackgram) effect on glycosaminoglycans, lipids and lipoprotein lipase activity in normal rats . Atherosclerosis. , 19 ( 2 ) : 315 – 326 .
  • Murthy , K. S. and Urs , K. M. 1985 . Effect of Bengal gram (Cicer arietinum) proteins and lipids on serum and liver cholesterol levels in rats . J. Food Sci. Technol. , 22 ( 1 ) : 54 – 56 .
  • Namba , T . 1980 . Phaseoli Semen, in a Full-Color Illustrated Book of Japanese Flora , Edited by: Namba , T. 298 Tokyo : Hoikusha .
  • Ndlovu , L. R. and Sibanda , L. M. 1996 . Potential of Dolichos lablab (Lablab purpureus) and Acacia tortilis pods in smallholder goat kid feeding systems in semi-arid areas of Southern Africa . Small Ruminant Res. , 2 ( I ) : 273 – 276 .
  • Nestel , P. , Cehun , M. and Chronopoulos , A. 2004 . Effects of long-term consumption and single meals of chickpeas on plasma glucose, insulin, and triacylglycerol concentrations . Am. J. Clin. Nutr. , 79 ( 3 ) : 390 – 395 .
  • Nishi , S. , Saito , Y. , Souma , C. , Kato , J. , Koaze , H. , Hironaka , K. and Kojima , M. 2008 . Suppression of serum cholesterol levels in mice by adzuki bean polyphenols . Food Sci. Technol. Res. , 14 ( 2 ) : 217 – 220 .
  • Nishimura , N. , Taniguchi , Y. and Kiriyama , S. 2000 . Plasma cholesterol-lowering effect on rats of dietary fiber extracted from immature plants . Biosci. Biotechnol. Biochem. , 64 : 2543 – 2551 .
  • Obiro , W. C. , Zhang , T. and Jiang , B. 2008 . The nutraceutical role of the Phaseolus vulgaris alpha-amylase inhibitor . Br. J. Nutr. , 100 ( 1 ) : 1 – 12 .
  • Obizoba , I. C. 1991 . Effect of sprouting on the nitrogenous constituents and mineral composition of pigeon pea (Cajanus cajan) seeds . Plant Foods Hum. Nutr. , 41 ( 1 ) : 21 – 26 .
  • Obon , H. A. and Omofoma , C. O. 2008 . The effects of heat treated lima beans (Phaseolus lunatus) on plasma lipids in hypercholesterolemic rats . Pakistan J. Nutr. , 7 ( 5 ) : 636 – 639 .
  • Pan , X. R. , Li , G. W. , Hu , Y. H. , Wang , J. X. , Yang , W. Y. An , Z. X. 1997 . Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance: The Da Qing IGT and Diabetes Study . Diabetes Care. , 20 : 537 – 544 .
  • Pandian , M. R. , Banu , G. S. , Kumar , G. and Smila , K. H. 2008 . “ Medicinal plants of ethnobotanical importance curing diabetes from namakkal district, Tamil Nadu, India ” . In Environmental Issues and Solutions 30 – 35 . Kumar A. and Roy P. K., eds. Daya Publishing House, New Delhi, India
  • Panlasigui , L. N. , Panlilio , L. M. and Madrid , J. C. 1995 . Glycemic response in normal subjects to five different legumes commonly used in the Philippines . Int. J. Food Sci. Nutr. , 46 ( 2 ) : 155 – 160 .
  • Pant , M. C. , Uddin , I. , Bhardwaj , U. R. and Tewari , R. D. 1968 . Blood sugar and total cholesterol lowering effect of Glycine soja (Sieb and Zucc.), Mucuna pruriens (D.C.) and Dolichos biflorus (Linn.) seed diets in normal fasting albino rats . Indian J. Med. Res. , 56 ( 12 ) : 1808 – 1812 .
  • Pari , L. and Venkateswaran , S. 2003 . Effect of an aqueous extract of Phaseolus vulgaris on plasma insulin and hepatic key enzymes of glucose metabolism in experimental diabetes . Pharmazie. , 58 ( 12 ) : 916 – 919 .
  • Pari , L. and Venkateswaran , S . 2004 . Protective role of Phaseolus vulgaris on changes in the fatty acid composition in experimental diabetes . J. Med. Food. , 7 ( 2 ) : 204 – 209 .
  • Patwardhan , V. N. 1962 . Pulses and beans in human nutrition . Am. J. Clin. Nutr. , 11 : 12 – 30 .
  • Pittaway , J. K. , Robertson , I. K. and Ball , M. J. 2008 . Chickpeas may influence fatty acid and fiber intake in an ad libitum diet, leading to small improvements in serum lipid profile and glycemic control . J Am Diet Assoc. , 108 ( 6 ) : 1009 – 1013 .
  • Polhill , R. M. and Raven , P. H. 1981 . Advances in Legume Systematics , Kew : Royal Botanic Gardens .
  • Prema , L and Kurup , P. A. 1973a . Effect of protein fractions from Cajanus cajan (redgram) and Dolichos biflorus (horsegram) on the serum, liver and aortic lipid levels in rats fed a high-fat-high-cholesterol diet . Atherosclerosis. , 18 ( 3 ) : 369 – 377 .
  • Prema , L. and Kurup , P. A. 1973b . Hypolipidemic activity of the protein isolated from Cajanus cajan in high fat-cholesterol diet fed rats . Indian J. Biochem. Biophys. , 10 : 293 – 296 .
  • Ramakrishna , V. , Rani , P. J. and Rao , P. R. 2007 . Hypocholesterolemic effect of diet supplemented with Indian bean (Dolichos lablab L. var lignosus) seeds . Nutr. Food Sci. , 37 ( 6 ) : 452 – 456 .
  • Rehman , Z. , Salariya , A. M. and Zafar , S. I. 2001 . Effect of processing on available carbohydrate content and starch digestibility of kidney beans (Phaseolus vulgaris L.) . Food Chem. , 73 : 351 – 355 .
  • Roman-Ramos , R. , Flores-Saenz , J. L. and Alarcon-Aguilar , F. J. 1995 . Anti-hyperglycemic effect of some edible plants . J Ethnopharmacol. , 48 ( 1 ) : 25 – 32 .
  • Rosenbloom , A. L. , Joe , J. R. , Young , R. S. and Winter , W. E. 1999 . Emerging epidemic of type 2 diabetes in youth . Diabetes Care. , 22 ( 2 ) : 345 – 354 .
  • Sacks , F. M. A . 1977 . Literature review of Phaseolus angularis—the adsuki bean . Econ. Bot. , 31 : 9 – 15 .
  • Saraswati , G. and Shurpalekar , K. S. 1986 . Effect of incorporation of field bean (Dolichos lablab) into hypercholesterolemic diets on cholesterol levels in rats . Arogya J. Health Sci , 12 : 113 – 116 .
  • Sato , S. , Yamate , J. , Hori , Y. , Hatai , A. , Nozawa , M. and Sagai , M. 2005 . Protective effect of polyphenol-containing azuki bean (Vigna angularis) seed coats on the renal cortex in streptozotocin-induced diabetic rats . J. Nutr. Biochem. , 16 ( 9 ) : 547 – 553 .
  • Satyavati , G. V. , Neeraj , T. and Madhu , S. 1989 . Indigenous plant drugs for diabetes mellitus . Diabetes Bulleta , 181 Q : 1 – 32 .
  • Savage , P. J. 1996 . Cardiovascular complications of diabetes mellitus: What we know and what we need to know about their prevention . Ann. Intern. Med , 124 ( 1, Part 2 ) : 123 – 126 .
  • Schäfe , G. , Schenk , U. , Ritzel , U. , Ramadori , G. and Leonhardt , U. 2003 . Comparison of the effects of dried peas with those of potatoes in mixed meals on postprandial glucose and insulin concentrations in patients with type 2 diabetes . Am. J. Clin. Nutr. , 78 : 99 – 103 .
  • Serrano , J. and Goñi , I . 2004 . Role of black bean Phaseolus vulgaris on the nutritional status of Guatemalan population . Arch. Latinoam Nutr. , 54 ( 1 ) : 36 – 44 .
  • Shams , H. , Tahbaz , F. , Entezari , M. and Abadi , A. 2008 . Effects of cooked lentils on glycemic control and blood lipids of patients with type 2 diabetes . ARYA Atherosclerosis J. , 3 ( 4 ) : 215 – 218 .
  • Sharma , R. D. 1984 . Hypercholesterolemic effect of hydroxyl acid components of Bengal gram . Nutr. Rep. Int. , 29 ( 6 ) : 1315 – 1322 .
  • Shehata , N. A. , Darwish , N. , Nahr , F. E. and Razek , F. A. A. 1988 . Supplementation of wheat flour with some local legumes . Die Nahrung. , 31 : 3 – 8 .
  • Shutler , S. M. , Bircher , G. M. , Tredger , J. A. , Morgan , L. M. and Walker , A. F. 1989 . The effect of daily baked bean (Phaseolus vulgaris) consumption on the plasma lipid levels of young, normo-cholesterolaemic men . Br. J. Nutr. , 61 : 257 – 265 .
  • Siddhuraju , P. 2006 . The antioxidant activity and free radical-scavenging capacity of phenolics of raw and dry heated moth bean (Vigna aconitifolia) (Jacq.) Marechal seed extracts . Food Chem. , 99 ( 1 ) : 149 – 157 .
  • Siddiqui , M. T. and Siddiqi , M. 1976 . Hypolipidemic principles of Cicer arietinum: Biochanin-A and formononetin . Lipids. , 11 ( 3 ) : 243 – 246 .
  • Sidhu , G. S. and Oakenfull , D. G. 1986 . A mechanism for the hypocholesterolemic activity of saponins . Br. J. Nutr. , 55 ( 3 ) : 643 – 649 .
  • Simpson , H. C. , Lousley , R. S. , Greekie , M. , Hockaday , T. D. R. , Carter , R. D. and Mann , J. I. 1981 . A high carbohydrate leguminous fibre diet improves all aspects of diabetes control . Lancet. , 1 : 1 – 4 .
  • Singh , J. , Handa , G. , Rao , P. R. and Atal , C. K. 1983 . Pangamic acid, a stamina buiding, antistress and antihyperlipidemic principle form Cicer arientinum L . J. Ethnopharmacol. , 7 ( 2 ) : 239 – 242 .
  • Singh , U. 1985 . Nutritional quality of chickpea (Cicer arietinum L.): Current status and future research needs . Plant Foods Hum. Nutr. , 35 : 339 – 351 .
  • Singh , U. and Singh , B. 1992 . Tropical grain legumes as important human foods . Econ. Bot. , 46 ( 3 ) : 310 – 321 .
  • Srivastava , A. and Joshi , L. D. 1990 . Effect of feeding black gram (Phaseolus mungo) on serum lipids of normal and diabetic guineapigs . Indian J. Med. Res. , 92 : 383 – 386 .
  • Srivastava , A. , Joshi , L. D. and Singh , S. P. 1989 . Changes in serum lipids in normal and diabetic guinea pigs on feeding Phaseolus aureus (green gram) . Indian J. Clin. Biochem. , 4 : 50 – 57 .
  • Tharanathan , R. N. and Mahadevamma , S. 2003 . Grain legumes—a boon to human nutrition . Trends Food Sci. Technol. , 14 ( 12 ) : 507 – 518 .
  • Tiwari , B. K. , JaganMohan , R. and Vasan , B. S. 2007 . Effect of heat processing on milling of black gram and its end product quality . J. Food Eng. , 78 : 356 – 360 .
  • Tormo , M. A. , Gil-Exojo , I. , Romero de Tejada , A. and Campillo , J. E. 2006 . White bean amylase inhibitor administered orally reduces glycaemia in type 2 diabetic rats . Br. J. Nutr. , 96 ( 3 ) : 539 – 544 .
  • Tormo , M. A. , Ropero , F. , Nieto , M. , Martinez , I. and Campillo , J. E. 1997 . Effect of peas (Pisum sativum) in the treatment of experimental non-insulin-dependent diabetes . Phytother. Res. , 11 : 39 – 41 .
  • Tovar , J. , Granfeldt , Y. and Bjorck , I. 1994 . Effect of processing on metabolic response to legumes . Am. J. Clin. Nutr. , 59 ( Suppl ) : 783S
  • Tuomilehto , J. , Lindström , J. , Eriksson , J. G. , Valle , T. T. , Hamalainen , H. and Ilanne-Parikka , P. 2001 . Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance . N Engl. J. Med. , 344 : 1343 – 1350 .
  • US Department of Agriculture . 2001 . Nutrient Database for Standard Reference. Release 14 , Washington , DC : US Department of Agriculture .
  • Vaidya , A. B. , Antarkar , D. S. and Joshi , B. S. 1989 . “ Traditional remedies for diabetes mellitus: Trails, trials and trilateral quest ” . Vol. 10 , 186 – 191 .
  • Venkateswaran , S. and Pari , L. 2002 . Antioxidant effect of Phaseolus vulgaris in streptozotocin-induced diabetic rats . Asia Pac. J. Clin. Nutr. , 11 ( 3 ) : 206 – 209 .
  • Venkateswaran , S. , Pari , L. and Saravanan , G. 2002 . Effect of Phaseolus vulgaris on circulatory antioxidants and lipids in rats with streptozotocin-induced diabetes . J. Med. Food , 5 ( 2 ) : 97 – 103 .
  • Vijayagopal , P. , Devi , K. S. and Kurup , P. A. 1973 . Fibre content of different dietary starches and their effect on lipid levels in high fat-high cholesterol diet fed rats . Atherosclerosis. , 17 ( 1 ) : 156 – 160 .
  • Villegas , R. , Gao , Y. , Yang , G. , Li , H. , Elasy , T. A. , Zheng , W. and Shu , X. O. 2008 . Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study . Am. J. Clin. Nutr. , 87 : 162 – 167 .
  • Warren , R. E. 2004 . The stepwise approach to the management of type 2 diabetes . Diabetes Res. Clin. Pract. , 65 ( 1 ) : S3 – S8 .
  • Weck , M. , Hanefeld , M. , Leonhardt , W. , Haller , H. , Robowsky , K. D. , Noack , R. and Schmandke , H. 1983 . [Field bean protein diet in hypercholesterolemia] . Nahrung. , 27 : 327 – 333 .
  • Wild , S. , Roglic , G. , Green , A. , Sicree , R. and King , H. 2004 . Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030 . Diabetes Care. , 27 : 1047 – 1053 .
  • Wolever , T. M. , Jenkins , D. J. , Vuksan , V. , Jenkins , A. L. , Buckley , G. C. , Wong , G. S. and Josse , R. G. 1992 . Beneficial effect of a low glycaemic index diet in type 2 diabetes . Diabet Med. , 9 ( 5 ) : 451 – 458 .
  • Wong , W. W. , O’Brian , Smith , E. , Stuff , J. E. , Hachey , D. L. , Heird , W. C. and Pownell , H. J. 1998 . Cholesterol-lowering effect of soy protein in normocholesterolemic and hypercholesterolemic men . Am. J. Clin. Nutr. , 68 ( 6 Suppl. ) : 1385S – 1389S .
  • Xiao , H. , Zhang , Y. M. and Zhang , W. Q. 2005 . Effect of refined chickpea powder in regulating blood glucose and blood lipid of diabetic rats . Zhongguo Linchuang Kangfu , 27
  • Xuezhe , Y. , Jishu , Q. , Takemichi , K. and Makoto , T. 2004 . Anti-atherosclerotic effect of soybean isoflavones and soyasaponins in diabetic rats . Zhonghua Yufang Yixue Zazhi. , 38 ( 1 ) : 26 – 28 .
  • Yang , Y. , Zhou , L. , Gu , Y. , Zhang , Y. , Tang , J. , Li , F. , Shang , W. , Jiang , B. , Yue , X. and Chen , M. 2007 . Dietary chickpeas reverse visceral adiposity, dyslipidaemia and insulin resistance in rats induced by a chronic high-fat diet . Br. J. Nutr. , 98 : 720 – 726 .
  • Yoshiaki , A. 2007 . Antidiabetic effects of soybean in the KK-A-y mice, a type 2 diabetes model . Nendo. , : 63 – 65 .
  • Zhan , S. and Ho , SC . 2005 . Meta-analysis of the effects of soy protein containing isoflavones on the lipid profile . Am. J. Clin. Nutr. , 81 : 397 – 408 .
  • Zhang , X. Q. , Yang , M. Y. , Ma , Y. , Tian , J. and Song , J. R. 2007 . Isolation and activity of an alpha-amylase inhibitor from white kidney beans . Yao Xue Xue Bao. , 42 ( 12 ) : 1282 – 1287 .
  • Zulet , M. A. , Macarulla , M. T. , Portillo , M. P. , Noel-Suberville , C. , Higueret , P. and Martínez , J. A. 1999 . Lipid and glucose utilization in hypercholesterolemic rats fed a diet containing heated chickpea (Cicer aretinum L.): A potential functional food . Int. J. Vitam. Nutr. Res. , 69 ( 6 ) : 403 – 411 .
  • Zulet , M. A. and Martinez , J. A. 1995 . Corrective role of chickpea intake on a dietary-induced model of hypercholesterolemia . Plant Foods Hum. Nutr. , 48 ( 3 ) : 269 – 277 .

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