Advances on the molecular characterization, clinical relevance, and detection methods of Gadiform parvalbumin allergens

References

• ALLERGEN, official site for the systematic allergen nomenclature. Available at: http://www.allergen.org/ (Last accessed 8 December 2014).
   Google Scholar
• ALLERGOME Database, the platform for allergen knowledge. Latina, Italy. Available at: http://www.allergome.org (Last accessed 8 December 2014).
   Google Scholar
• Alves, R. C., Barroso, M. F., Gonzállez-García, M. B., Oliveira, M. B. P. P. and Delerue-Matos, M. C. (2016). New trends in food allergens detection: towards biosensing strategies. Crit. Rev. Food Sci. Nutr. 56:2304–2319.
   PubMed Web of Science ®Google Scholar
• Arif, S. H. (2009). A Ca2+ binding protein with numerous roles and uses: parvalbumin in molecular biology and physiology. Bioessays. 31:410–421.
   PubMed Web of Science ®Google Scholar
• Arif, S. H., Jabeen, M. and Hasnain, A. U. (2007). Biochemical characterization and thermostable capacity of parvalbumins: The major fish-food allergens. J Food Biochem. 31:121–137.
   Web of Science ®Google Scholar
• Beale, J. E., Jeebhay, M. F. and Lopata, A. L. (2009). Characterisation of purified parvalbumin from five fish species and nucleotide sequencing of this major allergen from Pacific pilchard, Sardinops sagax. Mol Immunol. 46:2985–2993.
   PubMed Web of Science ®Google Scholar
• Ben-Shoshan, M., Harrington, D. W., Soller, L., Fragapane, J., Joseph, L., St Pierre, Y., Godefroy, S. B., Elliot, S. J. and Clarke, A. E. (2010). A population-based study on peanut, tree nut, fish, shellfish, and sesame allergy prevalence in Canada. J Allergy Clin Immunol. 125:1327–1335.
   PubMed Web of Science ®Google Scholar
• Berin, M. C. and Sampson, H. A. (2013). Food allergy: an enigmatic epidemic. Trends Immunol. 34:390–397.
   PubMed Web of Science ®Google Scholar
• Bernhisel-Broadbent, J., Scanlon, S. M. and Sampson, H. A. (1992). Fish hypersensitivity. I. In vitro and oral challenge results in fish- allergic patients. J Allergy Clin Immunol. 89:730–737.
   PubMed Web of Science ®Google Scholar
• Bock, S. A., Muoz-Furlong, A. and Sampson, H. A. (2001). Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol. 107:191–193.
   PubMed Web of Science ®Google Scholar
• Breiteneder, H. and Radauer, C. (2004). A classification of plant food allergens. J Allergy Clin Immunol. 113:821–830.
   PubMed Web of Science ®Google Scholar
• Breiteneder, H. and Mills, E. N. C. (2005a). Molecular properties of food allergens. J Allergy Clin Immunol. 115:14–23.
   PubMed Web of Science ®Google Scholar
• Breiteneder, H. and Mills, E. N. C. (2005b). Plant food allergens - structural and functional aspects of allergenicity. Biotechnol Adv. 23:395–399.
   PubMed Web of Science ®Google Scholar
• Bugajska-Schretter, A., Elfman, L., Fuchs, T., Kaplotis, S., Rumpold, H., Valenta, R. and Spitzauer, S. (1998). Parvalbumin, a cross-reactive fish allergen, contains IgE-binding epitopes sensitive to periodate treatment and Ca2+ depletion. J Allergy Clin Immunol. 101:67–74.
   PubMed Web of Science ®Google Scholar
• Bugajska-Schretter, A., Grote, M., Vangelista, L., Valent, P., Sperr, W. R., Rumpold, H., Pastore, A., Reichelt, R., Valenta, R. and Spitzauer, S. (2000). Purification, biochemical, and immunological characterisation of a major food allergen: different immunoglobulin E recognition of the apo- and calcium-bound forms of carp parvalbumin. Gut. 46:661–669.
   PubMed Web of Science ®Google Scholar
• Burks, A. W., Tang, M., Sicherer, S., Muraro, A., Eigenmann, P. A., Ebisawa, M., Fiocchi, A., Chiang, W., Beyer, K., Wood, R., Hourihane, J., Jones, S. M., Lack, G. and Sampson, H. A. (2012). ICON: Food allergy. J Allergy Clin Immunol. 129:906–920.
   PubMed Web of Science ®Google Scholar
• Burney, P. G. J., Potts, J., Kummeling, I., Mills, E. N. C., Clausen, M., Dubakiene, R., Barreales, L., Fernandez-Perez, C., Fernandez-Rivas, M., Le, T. M., Knulst, A. C., Kowalski, M. L., Lidholm, J., Ballmer-Weber, B. K., Braun-Fahlander, C., Mustakov, T., Kralimarkova, T., Popov, T., Sakellariou, A., Papadopoulos, N. G., Versteeg, S. A., Zuidmeer, L., Akkerdaas, J. H., Hoffmann-Sommergruber, K. and van Ree, R. (2014). The prevalence and distribution of food sensitization in European adults. Allergy. 69:365–371.
   PubMed Web of Science ®Google Scholar
• Burney, P., Summers, C., Chinn, S., Hooper, R., Van Ree, R. and Lidholm, J. (2010). Prevalence and distribution of sensitization to foods in the European Community Respiratory Health Survey: a EuroPrevall analysis. Allergy. 65:1182–1188.
   PubMed Web of Science ®Google Scholar
• Chen, Y. T. and Hsieh, Y. H. P. (2014). A sandwich ELISA for the detection of fish and fish products. Food Control. 40:265–273.
   Web of Science ®Google Scholar
• Calo-Mata, P., Sotelo, C. G., Pérez-Martín, R. I., Rehbein, H., Hold, G. L., Russel, V. J., Pryde, S., Quinteiro, J., Rey-Méndez, M., Rosa, C. and Santos, A. T. (2003). Identification of gadoid fish species using DNA-based techniques. Eur Food Res Technol. 217:259–264.
   Web of Science ®Google Scholar
• Capony, J. P. and Pechère, J. F. (1973). The primary structure of the major parvalbumin from hake muscle. Tryptic peptides derived from the S-sulfo and the performic-acid-oxidized proteins. Eur J Biochem. 32:88–96.
   PubMedGoogle Scholar
• Carrera, M., Cañas, B. and Gallardo, J. M. (2012). Rapid direct detection of the major fish allergen, parvalbumin, by selected MS/MS ion monitoring mass spectrometry. J Proteomics. 75:3211–3220.
   PubMed Web of Science ®Google Scholar
• Carrera, M., Cañas, B., Vázquez, J. and Gallardo, J. M. (2010). Extensive de Novo sequencing of new parvalbumin isoforms using a novel combination of bottom-up proteomics, accurate molecular mass measurement by FTICR-MS, and selected MS/MS ion monitoring. J Proteome Res. 9:4393–4406.
   PubMed Web of Science ®Google Scholar
• Carrera, M., Cañas, B., Piñeiro, C., Vázquez, J. and Gallardo, J. M. (2006). Identification of commercial hake and grenadier species by proteomic analysis of the parvalbumin fraction. Proteomics. 6:5278–5287.
   PubMed Web of Science ®Google Scholar
• Chafen, J. J. S., Newberry, S. J., Riedl, M. A., Bravata, D. M., Maglione, M., Suttorp, M. J., Sundaram, V., Paige, N. M., Towfigh, A., Hulley, B. J. and Shekelle, P. G. (2010). Diagnosing and managing common food allergies: A systematic review. J Amer Med Assoc. 303:1848–1856.
   PubMed Web of Science ®Google Scholar
• Chapman, M. D., Pomés, A., Breiteneder, H. and Ferreira, F. (2007). Nomenclature and structural biology of allergens. J Allergy Clin Immunol. 119:414–420.
   PubMed Web of Science ®Google Scholar
• Chapman, M. D. (2008). Allergen Nomenclature. In: Allergens and Allergen Immunotherapy, pp. 47–58. Lockey, R. F. and Ledford, D. K., Eds., Informa Healthcare, New York.
   Google Scholar
• CODEX STAN 1–1985. (2010). Amended in 1991, 1999, 2001, 2003, 2005, 2008 and 2010 regarding the general standard for the labelling of pre-packaged foods. FAO/WHO Standards, Off Codex Stand. Rome, Italy. Available at: http://www.codexalimentarius.org/standards/list-of-standards. (Last accessed 4 December 2014).
   Google Scholar
• Cohen, D. M., Inada, T., Iwamoto, T. and Scialabba, N. (1990). FAO species catalogue. Gadiform fishes of the world (Order Gadiformes). An annotated and illustrated catalogue of cods, hakes, grenadiers and other gadiform fishes known to date. In: FAO Fisheries Synopsis, pp 442, FAO, Rome.
   Google Scholar
• Costa, J., Carrapatoso, I., Oliveira, M. B. P. P. and Mafra, I. (2014). Walnut allergens: Molecular characterization, detection and clinical relevance. Clin Experim Allergy. 44:319–341.
   PubMed Web of Science ®Google Scholar
• Das Dores, S., Chopin, C., Villaume, C., Fleurence, J. and Guéant, J. L. (2002). A new oligomeric parvalbumin allergen of Atlantic cod (Gad mI) encoded by a gene distinct from that of Gad cI. Allergy: Eur J Allergy Clin Immunol, Supp. 57:79–83.
   Web of Science ®Google Scholar
• De Martino, M., Novembre, E., Galli, L., De Marco, A., Botarelli, P., Marano, E. and Vierucci, A. (1990). Allergy to different fish species in cod-allergic children: In vivo and in vitro studies. J Allergy Clin Immunol. 86:909–914.
   PubMed Web of Science ®Google Scholar
• Diaz-Amigo, C. (2010). Antibody-based detection methods: from theory to practice. In: Molecular biological and immunological techniques and applications for food chemists, pp. 223–245. Popping, B., Diaz-Amigo, C. and Hoenicke, K., Eds., John Wiley & Sons Inc., New Jersey.
   Google Scholar
• Di Finizio, A., Guerriero, G., Russo, G. L. and Ciarcia, G. (2007). Identification of gadoid species (Pisces, Gadidae) by sequencing and PCR-RFLP analysis of mitochondrial 12S and 16S rRNA gene fragments. Eur Food Res Technol. 227:337–344.
   Web of Science ®Google Scholar
• Directive 2006/142/EC of 22 December 2006 amending Annex IIIa of Directive 2000/13/EC of the European Parliament and of the Council listing the ingredients which must under all circumstances appear on the labelling of foodstuffs. Official Journal of the European Union L368:110–111.
   Google Scholar
• Directive 2007/68/EC of 27 November 2007 amending Annex IIIa to Directive 2000/13/EC regarding certain food ingredients. Official Journal of the European Union L310:11–14.
   Google Scholar
• EFSA. (2014). Scientific Opinion on the evaluation of allergenic foods and food ingredients for labelling purposes. EFSA J. 12:1–286.
   Google Scholar
• Eischeid, A. C., Kim, B. H. and Kasko, S. M. (2013). Two quantitative real-time PCR assays for the detection of penaeid shrimp and blue crab, crustacean shellfish allergens. J Agri Food Chem. 61:5669–5674.
   PubMed Web of Science ®Google Scholar
• Elsayed, S. and Apold, J. (1983). Immunochemical analysis of cod fish Allergen M: Locations of the immunoglobulin binding sites as demonstrated by the native and synthetic peptides. Allergy: Eur J Allergy Clin Immunol. 38:449–459.
   Web of Science ®Google Scholar
• Elsayed, S. and Bennich, H. (1975). The primary structure of allergen M from cod. Scand J Immunol. 4:203–208.
   PubMed Web of Science ®Google Scholar
• Elsayed, S., Ragnarsson, U., Apold, J., Florvaag, E. and Vik, H. (1981). Allergenic synthetic peptide corresponding to the second calcium-binding loop of cod Allergen M. Scand J Immunol. 14:207–211.
   PubMed Web of Science ®Google Scholar
• Elsayed, S., von Bahr Lindström, H. and Bennich, H. (1974). The primary structure of fragment TM2 of allergen M from cod. Scand J Immunol. 3:683–686.
   PubMed Web of Science ®Google Scholar
• Fernandes, T. J. R., Costa, J., Plácido, A., Villa, C., Grazina, L., Meira, L., Oliveira, M. B. P P., and Mafra, I. (2016). GMO analysis as affected by DNA degradation. In Genetically Modified Organisms in Foods, pp. 111–118. Watson, R. and Preedy, V. R., Eds, Elsevier, USA.
   Google Scholar
• Fæste, C. K. and Plassen, C. (2008). Quantitative sandwich ELISA for the determination of fish in foods. J Immunol Meth. 329:45–55.
   PubMed Web of Science ®Google Scholar
• Fæste, C. K., Rønning, H. T., Christians, U. and Granum, P. E. (2011). Liquid chromatography and mass spectrometry in food allergen detection. J Food Protection. 74:316–345.
   PubMed Web of Science ®Google Scholar
• FAO. (2014). Food and Agriculture Organization of the United Nations. Rome, Italy. Available at: http://www.fao.org/ (Last accessed 3 December 2014).
   Google Scholar
• González-de-Olano, D., Bartolomé, B., Maroto, A. S., Vivanco, F. and Pastor-Vargas, C. (2012). Asthma after chicken consumption due to cross-reactivity between fish and chicken parvalbumin. J Invest Allergol Clin Immunol. 22:227–228.
   PubMed Web of Science ®Google Scholar
• Grabarek, Z. (2006). Structural basis for diversity of the EF-hand calcium-binding proteins. J Mol Biol. 359:509–525.
   PubMed Web of Science ®Google Scholar
• Griesmeier, U., Vázquez-Cortés, S., Bublin, M., Radauer, C., Ma, Y., Briza, P., Fernández-Rivas, M. and Breiteneder, H. (2010). Expression levels of parvalbumins determine allergenicity of fish species. Allergy: Eur J Allergy Clin Immunol. 65:191–198.
   Web of Science ®Google Scholar
• Heizmann, C. W. (1984). Parvalbumin, an intracellular calcium-binding protein; distribution, properties and possible roles in mammalian cells. Experientia. 40:910–921.
   PubMedGoogle Scholar
• Helbling, A., Haydel, Jr, R., McCants, M. L., Musmand, J. J., El-Dahr, J. and Lehrer, S. B. (1999). Fish allergy: Is cross-reactivity among fish species relevant? Double- blind placebo-controlled food challenge studies of fish allergic adults. Ann Allergy, Asthma, Immunol. 83:517–523.
   PubMed Web of Science ®Google Scholar
• Herrero, B., Vieites, J. M. and Espiñeira, M. (2014). Development of an in-house fast real-time PCR method for detection of fish allergen in foods and comparison with a commercial kit. Food Chem. 151:415–420.
   PubMed Web of Science ®Google Scholar
• Hildebrandt, S. (2010). Multiplexed identification of different fish species by detection of parvalbumin, a common fish allergen gene: A DNA application of multi-analyte profiling (xMAP™) technology. Anal Bioanal Chem. 397:1787–1796.
   PubMed Web of Science ®Google Scholar
• InFormAll Database, communicating about Food Allergies. Available at: http://www.inflammation-repair.manchester.ac.uk/informAll/ (Last accessed 9 December 2014).
   Google Scholar
• Ikura, M. (1996). Calcium binding and conformational response in EF-hand proteins. Trends Biochem Sci. 21:14–17.
   PubMed Web of Science ®Google Scholar
• Jeebhay, M. F., Robins, T. G., Miller, M. E., Bateman, E., Smuts, M., Baatjies, R. and Lopata, A. L. (2008). Occupational allergy and asthma among salt water fish processing workers. Amer J Indust Med. 51:899–910.
   PubMed Web of Science ®Google Scholar
• Jenkins, J. A., Breiteneder, H. and Mills, E. N. C. (2007). Evolutionary distance from human homologs reflects allergenicity of animal food proteins. J Allergy Clin Immunol. 120:1399–1405.
   PubMed Web of Science ®Google Scholar
• Joassin, L. and Gerday, C. (1977). The amino acid sequence of the major parvalbumin of the whiting (Gadus merlangus). Comp Biochem Physiol B. 57:159–161.
   PubMed Web of Science ®Google Scholar
• Kamath, S. D., Abdel Rahman, A. M., Komoda, T. and Lopata, A. L. (2013). Impact of heat processing on the detection of the major shellfish allergen tropomyosin in crustaceans and molluscs using specific monoclonal antibodies. Food Chem. 141:4031–4039.
   PubMed Web of Science ®Google Scholar
• Koppelman, S. J., Nordlee, J. A., Lee, P. W., Happe, R. P., Hessing, M., Norland, R., Manning, T., Deschene, R., de Jong, G. A. H. and Taylor, S. L. (2012). Parvalbumin in fish skin-derived gelatin: Is there a risk for fish allergic consumers? Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 29:1347–1355.
   PubMed Web of Science ®Google Scholar
• Kuehn, A., Hilger, C., Lehners-Weber, C., Codreanu-Morel, F., Morisset, M., Metz-Favre, C., Pauli, G., de Blay, F., Revets, D., Muller, C. P., Vogel, L., Vieths, S. and Hentges, F. (2013). Identification of enolases and aldolases as important fish allergens in cod, salmon and tuna: Component resolved diagnosis using parvalbumin and the new allergens. Clin Exp Allergy. 43:811–822.
   PubMed Web of Science ®Google Scholar
• Kuehn, A., Scheuermann, T., Hilger, C. and Hentges, F. (2010). Important variations in parvalbumin content in common fish species: A factor possibly contributing to variable allergenicity. Int Arch Allergy Immunol. 153:359–366.
   PubMed Web of Science ®Google Scholar
• Larsen, R., Eilertsen, K-E. and Elvevoll, E. O. (2011). Health benefits of marine foods and ingredients. Biotechnol Adv. 29:508–518.
   PubMed Web of Science ®Google Scholar
• Lee, P. W., Nordlee, J. A., Koppelman, S. J., Baumert, J. L. and Taylor, S. L. (2011). Evaluation and comparison of the species-specificity of 3 antiparvalbumin IgG antibodies. J Agri Food Chem. 59:12309–12316.
   PubMed Web of Science ®Google Scholar
• Lee, P. W. and Taylor, S. L. (2011). Fish, Crustaceans, and Mollusks. In: Food Allergens–Analysis Instrumentation and Methods, pp. 117–205. Hengel, A. J. and Nollet, L. M. L., Eds., CRC Press, Taylor & Francis Group, Boca Raton.
   Google Scholar
• Lindstrom, C. D. V., Van Do, T., Hordvik, I., Endresen, C. and Elsayed, S. (1996). Cloning of two distinct cDNAs encoding parvalbumin, the major allergen of Atlantic salmon (Salmo salar). Scand J Immunol. 44:335–344.
   PubMed Web of Science ®Google Scholar
• Lloris, D., Matallanas, J. and Oliver, P. (2005). Hakes of the world (Family Merlucciidae). An annotated and illustrated catalogue of hake species known to date. In: Species Catalogue for Fishery Purposes, pp 1–57. FAO, Rome.
   Google Scholar
• Lu, Y., Ohshima, T. and Ushio, H. (20004). Rapid detection of fish major allergen parvalbumin by surface plasmon resonance biosensor. J Food Sci. 69:C652–C658.
   Google Scholar
• Ma, Y., Griesmeier, U., Susani, M., Radauer, C., Briza, P., Erler, A., Bublin, M., Alessandri, S., Himly, M., Vàzquez-Cortés, S., de Arellano, I. R., Vassilopoulou, E., Saxoni-Papageorgiou, P., Knulst, A. C., Fernández-Rivas, M., Hoffmann-Sommergruber, K. and Breiteneder, H. (2008). Comparison of natural and recombinant forms of the major fish allergen parvalbumin from cod and carp. Mol Nutr Food Res. 52:196–207.
   PubMed Web of Science ®Google Scholar
• Mafra, I., Ferreira, I. M. P. L. V. O. and Oliveira, M. B. P. P. (2008). Food authentication by PCR-based methods. Eur Food Res Technol. 227:649–665.
   Web of Science ®Google Scholar
• Mari, A., Rasi, C., Palazzo, P. and Scala, E. (2009). Allergen databases: Current status and perspectives. Curr Allergy Asthma Rep. 9:376–383.
   PubMed Web of Science ®Google Scholar
• Minkiewicz, P., Bucholska, J., Darewicz, M. and Borawska, J. (2012). Epitopic hexapeptide sequences from Baltic cod parvalbumin beta (allergen Gad c 1) are common in the universal proteome. Peptides. 38:105–109.
   PubMed Web of Science ®Google Scholar
• Monaci, L. and Visconti, A. (2010). Immunochemical and DNA-based methods in food allergen analysis and quality assurance perspectives. Trends Food Sci Tech. 21:272–283.
   Web of Science ®Google Scholar
• Moraes, A. H., Ackerbauer, D., Kostadinova, M., Bublin, M., Ferreira, F., Almeida, F. C. L., Breiteneder, H. and Valente, A. P. (2013). 1H, 13C and 15N resonance assignments and second structure information of Gad m 1: a β-parvalbumin allergen from Atlantic cod (Gadus morhua). Biomolecular NMR Assignments. 7:133–136.
   PubMed Web of Science ®Google Scholar
• Mozaffarian, D., Bryson, C. L., Lemaitre, R. N., Siscovick, D. S. and Burke, G. L. (2005). Fish intake and risk of incident heart failure. J Amer Col Cardiol. 45:2015–2021.
   PubMed Web of Science ®Google Scholar
• NCBI, National Center for Biotechnology Information. Bethesda, USA. Available at: http://www.ncbi.nlm.nih.gov/ (Last accessed 12 November 2014).
   Google Scholar
• Nwaru, B. I., Hickstein, L., Panesar, S. S., Muraro, A., Werfel, T., Cardona, V., Dubois, A. E. J., Halken, S., Hoffmann-Sommergruber, K., Poulsen, L. K., Roberts, G., Van Ree, R., Vlieg-Boerstra, B. J. and Sheikh, A. (2014). The epidemiology of food allergy in Europe: A systematic review and meta-analysis. Allergy: Eur J Allergy Clin Immunol. 69:62–75.
   Web of Science ®Google Scholar
• Pechère, J. F., Capony, J. P. and Ryden, L. (1971). The primary structure of the major parvalbumin from hake muscle. Isolation and general properties of the protein. Eur J Biochem. 23:421–428.
   PubMedGoogle Scholar
• Pegels, N., González, I., López-Calleja, I., García, T. and Martín, R. (2013). Detection of fish-derived ingredients in animal feeds by a TaqMan real-time PCR assay. Food Anal Methods. 6:1040–1048.
   Web of Science ®Google Scholar
• Perez-Gordo, M., Cuesta-Herranz, J., Maroto, A. S., Cases, B., Ibáñez, M. D., Vivanco, F. and Pastor-Vargas, C. (2011). Identification of sole parvalbumin as a major allergen: Study of cross-reactivity between parvalbumins in a Spanish fish-allergic population. Clin Exp Allergy. 41:750–758.
   PubMed Web of Science ®Google Scholar
• Permyakov, S. E., Bakunts, A. G., Denesyuk, A. I., Knyazeva, E. L., Uversky, V. N. and Permyakov, E. A. (2008). Apo-parvalbumin as an intrinsically disordered protein. Proteins: Struct, Funct, Genet. 72:822–836.
   PubMed Web of Science ®Google Scholar
• Permyakov, E. A., Yarmolenko, V. V., Emelyanenko, V. I., Burstein, E. A., Closset, J. and Gerday, C. (1980). Fluorescence studies of the calcium binding to whiting (Gadus merlangus) parvalbumin. Eur J Biochem. 109:307–315.
   PubMedGoogle Scholar
• Pilolli, R., Monaci, L. and Visconti, A. (2013). Advances in biosensor development based on integrating nanotechnology and applied to food-allergen management. Trends Anal. Chem. 47:12–26.
   Web of Science ®Google Scholar
• Piñeiro, C., Barros-Velázquez, J., Sotelo, C. G., Pérez-Martín, R. I. and Gallardo, J. M. (1998). Two-dimensional electrophoretic study of the water-soluble protein fraction in white muscle of gadoid fish species. J Agri Food Chem. 46:3991–3997.
   Web of Science ®Google Scholar
• Plácido, A., Amaral, J. S., Costa, J., Fernandes, T. J. R., Oliveira, M. B. P. P., Delerue-Matos, C. and Mafra, I. (2016). Novel strategies for genetically modified organism detection. In Genetically Modified Organisms in Foods, pp. 119–131. Watson, R. and Preedy, V. R., Eds, Elsevier, USA.
   Google Scholar
• Prado, M., Boix, A. and von Holst, C. (2012). Novel approach for the simultaneous detection of DNA from different fish species based on a nuclear target: quantification potential. Anal Bioanal Chem. 403:3041–3050.
   PubMed Web of Science ®Google Scholar
• Prado, M., Ortea, I., Vial, S., Rivas, J., Calo-Mata, P. and Barros-Velázquez, J. (2016). Advanced DNA- and protein-based methods for the detection and investigation of food allergens. Crit. Rev. Food Sci. Nutr. 56:2511–2542.
   PubMed Web of Science ®Google Scholar
• Priftis, K. N., Mermiri, D., Papadopoulou, A., Papadopoulos, M., Fretzayas, A. and Lagona, E. (2008). Asthma symptoms and bronchial reactivity in school children sensitized to food allergens in infancy. J Asthma. 45:590–595.
   PubMed Web of Science ®Google Scholar
• Radauer, C. and Breiteneder, H. (2007). Evolutionary biology of plant food allergens. J Allergy Clin Immunol. 120:518–525.
   PubMed Web of Science ®Google Scholar
• Radauer, C., Bublin, M., Wagner, S., Mari, A. and Breiteneder, H. (2008). Allergens are distributed into few protein families and possess a restricted number of biochemical functions. J Allergy Clin Immunol. 121:847–852.e847.
   PubMed Web of Science ®Google Scholar
• Rancé, F., Kanny, G., Dutau, G. and Moneret-Vautrin, D. A. (1999). Food hypersensitivity in children: Clinical aspects and distribution of allergens. Pediatr Allergy Immunol. 10:33–38.
   PubMed Web of Science ®Google Scholar
• Regulation (EU) No 1169/2011 of 25 October 2011 on the provision of food information to consumers, amending Regulations (EC) No 1924/2006 and (EC) No 1925/2006 of the European Parliament and of the Council, and repealing Commission Directive 87/250/EEC, Council Directive 90/496/EEC, Commission Directive 1999/10/EC, Directive 2000/13/EC of the European Parliament and of the Council, Commission Directives 2002/67/EC and 2008/5/EC and Commission Regulation (EC) No 608/2004. Official Journal of the European Union L304:18–63.
   Google Scholar
• Rencova, E., Kostelnikova, D. and Tremlova, B. (2013). Detection of allergenic parvalbumin of Atlantic and Pacific herrings in fish products by PCR. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 30:1679–1683.
   PubMed Web of Science ®Google Scholar
• Resource Program Allergen Database, Home of the FARRP allergen protein database. Available at http://www.allergenonline.com (Last accessed 9 December 2014).
   Google Scholar
• Revett, S. P., King, G., Shabanowitz, J., Hunt, D. F., Hartman, K. L., Laue, T. M. and Nelson, D. J. (1997). Characterization of a helix-loop-helix (EF hand) motif of silver hake parvalbumin isoform B. Protein Sci. 6:2397–2408.
   PubMed Web of Science ®Google Scholar
• Richardson, R. C., King, N. M., Harrington, D. J., Sun, H., Royer, W. E. and Nelson, D. J. (2000). X-ray crystal structure and molecular dynamics simulations of silver hake parvalbumin (Isoform B). Protein Sci. 9:73–82.
   PubMed Web of Science ®Google Scholar
• RCSB-PDB Research Collaboratory for Structural Bioinformatics-Protein Data Bank, an information portal to biological macromolecular structures. Available at http://www.rcsb.org (Last accessed 12 November 2014).
   Google Scholar
• Sharp, M. F. and Lopata, A. L. (2013). Fish Allergy: In review. Clin Rev Allergy Immunol. 1–14.
   Web of Science ®Google Scholar
• Sicherer, S. H., Morrow, E. H. and Sampson, H. A. (2000). Dose–response in double-blind, placebo-controlled oral food challenges in children with atopic dermatitis. J Allergy Clin Immunol. 105:582–586.
   PubMed Web of Science ®Google Scholar
• Sicherer, S. H., Muñoz-Furlong, A. and Sampson, H. A. (2004). Prevalence of seafood allergy in the United States determined by a random telephone survey. J Allergy Clin Immunol. 114:159–165.
   PubMed Web of Science ®Google Scholar
• Sicherer, S. H. and Sampson, H. A. (2009). Food allergy: Recent advances in pathophysiology and treatment. Ann Rev Med. 60:261–277.
   PubMed Web of Science ®Google Scholar
• Sicherer, S. H. and Sampson, H. A. (2010). Food allergy. J Allergy Clin Immunol. 125:116–125.
   PubMed Web of Science ®Google Scholar
• Sirot, V., Oseredczuk, M., Bemrah-Aouachria, N., Volatier, J-L. and Leblanc, J-C. (2008). Lipid and fatty acid composition of fish and seafood consumed in France: CALIPSO study. J Food Compos Anal. 21:8–16.
   Web of Science ®Google Scholar
• Somkuti, J., Bublin, M., Breiteneder, H. and Smeller, L. (2012). Pressure-temperature stability, Ca2+ binding, and pressure-temperature phase diagram of cod parvalbumin: Gad m 1. Biochem. 51:5903–5911.
   PubMed Web of Science ®Google Scholar
• Sletten, G., Van Do, T., Lindvik, H., Egaas, E. and Florvaag, E. (2010). Effects of industrial processing on the immunogenicity of commonly ingested fish species. Int Arch Allergy Immunol. 151:223–236.
   PubMed Web of Science ®Google Scholar
• Sun, M., Liang, C., Gao, H., Lin, C. and Deng, M. (2009). Detection of parvalbumin, a common fish allergen gene in food, by real-time polymerase chain reaction. J AOAC Int. 92:234–240.
   PubMed Web of Science ®Google Scholar
• Taylor, S. L. and Baumert, J. L. (2015). Worlwide food allergy labeling and detection of allergens in processed foods. In: Food Allergy: Molecular Basis and Clinical Practice. Chemical Immunology and Allergy, vol 101, pp 227–234. Ebisawa, M., Ballmer-Weber, B. K., Vieths, S. and Wood, R. A., Eds., Basel, Karger.
   Google Scholar
• Thong, B. Y. H., Cheng, Y. K., Leong, K. P., Tang, C. Y. and Chng, H. H. (2007). Immediate food hypersensitivity among adults attending a clinical immunology/allergy centre in Singapore. Singapore Med J. 48:236–240.
   PubMedGoogle Scholar
• Tsabouri, S., Triga, M., Makris, M., Kalogeromitros, D., Church, M. K. and Priftis, K. N. (2012). Fish and shellfish allergy in children: Review of a persistent food allergy. Pediatr Allergy Immunol. 23:608–615.
   PubMed Web of Science ®Google Scholar
• UniProt, Protein knowledgebase, UniProt Consortium. Available at: http:// www.uniprot.org/ (Last accessed 12 November 2014).
   Google Scholar
• Van Do, T., Hordvik, I., Endresen, C. and Elsayed, S. (2003). The major allergen (parvalbumin) of codfish is encoded by at least two isotypic genes: cDNA cloning, expression and antibody binding of the recombinant allergens. Mol Immunol. 39:595–602.
   PubMed Web of Science ®Google Scholar
• Van Do, T., Elsayed, S., Florvaag, E., Hordvik, I. and Endresen, C. (2005a). Allergy to fish parvalbumins: Studies on the cross-reactivity of allergens from 9 commonly consumed fish. J Allergy Clin Immunol. 116:1314–1320.
   PubMed Web of Science ®Google Scholar
• Van Do, T., Hordvik, I., Endresen, C. and Elsayed, S. (2005b). Characterization of parvalbumin, the major allergen in Alaska pollack, and comparison with codfish allergen M. Mol Immunol. 42:345–353.
   PubMed Web of Science ®Google Scholar
• Vierk, K. A., Koehler, K. M., Fein, S. B. and Street, D. A. (2007). Prevalence of self-reported food allergy in American adults and use of food labels. J Allergy Clin Immunol. 119:1504–1510.
   PubMed Web of Science ®Google Scholar
• Wang, J. and Sampson, H. A. (2011). Food allergy. J Clin Invest. 121:827–835.
   PubMed Web of Science ®Google Scholar
• Wang, W., Han, J., Wu, Y., Yuan, F., Chen, Y. and Ge, Y. (2011). Simultaneous detection of eight food allergens using optical thin-film biosensor chips. J Agric Food Chem. 59:6889–6894.
   PubMed Web of Science ®Google Scholar
• Weber, P., Steinhart, H. and Paschke, A. (2009). Competitive indirect ELISA for the determination of parvalbumins from various fish species in food grade fishgelatins and isinglass with PARV-19 anti-parvalbumin antibodies. J Agri Food Chem. 57:11328–11334.
   PubMed Web of Science ®Google Scholar
• Wopfner, N., Dissertori, O., Ferreira, F. and Lackner, P. (2007). Calcium-binding proteins and their role in allergic diseases. Immunol Allergy Clin North Amer. 27:29–44.
   PubMed Web of Science ®Google Scholar
• Zheng, C., Wang, X., Lu, Y. and Liu, Y. (2012). Rapid detection of fish major allergen parvalbumin using superparamagnetic nanoparticle-based lateral flow immunoassay. Food Control. 26:446–452.
   Web of Science ®Google Scholar
• Zuidmeer, L., Goldhahn, K., Rona, R. J., Gislason, D., Madsen, C., Summers, C., Sodergren, E., Dahlstrom, J., Lindner, T., Sigurdardottir, S. T., McBride, D. and Keil, T. (2008). The prevalence of plant food allergies: A systematic review. J Allergy Clin Immunol. 121:1210–1218.e1214.
   PubMed Web of Science ®Google Scholar