A systematic review of lactoferrin use in dermatology

References

• Beljaars, L., van der Strate, B. W., Bakker, H. I., Reker-Smit, C., van Loenen-Weemaes, A. M., Wiegmans, F. C., Harmsen, M. C., Molema, G. and Meijer, D. K. (2004). Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo. Antiviral Res. 63(3):197–208.
   PubMed Web of Science ®Google Scholar
• Bellamy, W., Wakabayashi, H., Takase, M., Kawase, K., Shimamura, S. and Tomita, M. (1993). Killing of Candida albicans by lactoferricin B, a potent antimicrobial peptide derived from the N-terminal region of bovine lactoferrin. Med. Microbiol. Immunol. 182(2):97–105.
   PubMed Web of Science ®Google Scholar
• Breton-Gorius, J., Mason, D. Y., Buriot, D., Vilde, J. L. and Griscelli, C. (1980). Lactoferrin deficiency as a consequence of a lack of specific granules in neutrophils from a patient with recurrent infections. Detection by immunoperoxidase staining for lactoferrin and cytochemical electron microscopy. Am J. Pathol. 99(2):413–428.
   PubMed Web of Science ®Google Scholar
• Coughlin, R. T., Tonsager, S. and McGroarty, E. J. (1983). Quantitation of metal cations bound to membranes and extracted lipopolysaccharide of Escherichia coli. Biochemistry. 22(8):2002–2007.
   PubMed Web of Science ®Google Scholar
• Crouch, S. P., Slater, K. J. and Fletcher, J. (1992). Regulation of cytokine release from mononuclear cells by the iron-binding protein lactoferrin. Blood. 80(1):235–240.
   PubMed Web of Science ®Google Scholar
• Ellison, R. T., 3rd and Giehl, T. J. (1991). Killing of gram-negative bacteria by lactoferrin and lysozyme. J. Clin. Invest. 88(4):1080–1091.
   PubMed Web of Science ®Google Scholar
• Ellison, R. T., 3rd, Giehl, T. J. and LaForce, F. M. (1988). Damage of the outer membrane of enteric gram-negative bacteria by lactoferrin and transferrin. Infect. Immun. 56(11):2774–2781.
   PubMed Web of Science ®Google Scholar
• Fischer, R., Debbabi, H., Dubarry, M., Boyaka, P. and Tome, D. (2006). Regulation of physiological and pathological Th1 and Th2 responses by lactoferrin. Biochem. Cell Biol. 84(3):303–311.
   PubMed Web of Science ®Google Scholar
• Griffiths, C. E. M., Cumberbatch, M., Tucker, S. C., Dearman, R. J., Andrew, S., Headon, D. R. and Kimber, I. (2001). Exogenous topical lactoferrin inhibits allergen-induced Langerhans cell migration and cutaneous inflammation in humans. British J. Dermatol. 144(4):715–725.
   PubMed Web of Science ®Google Scholar
• Hasegawa, K., Motsuchi, W., Tanaka, S. and Dosako, S. (1994). Inhibition with lactoferrin of in vitro infection with human herpes virus. Jpn. J. Med. Sci. Biol. 47(2):73–85.
   PubMedGoogle Scholar
• Kaito, M., Iwasa, M., Fujita, N., Kobayashi, Y., Kojima, Y., Ikoma, J., Imoto, I., Adachi, Y., Hamano, H. and Yamauchi, K. (2007). Effect of lactoferrin in patients with chronic hepatitis C: Combination therapy with interferon and ribavirin. J. Gastroenterol. Hepatol. 22(11):1894–1897.
   PubMed Web of Science ®Google Scholar
• Kim, J., Ko, Y., Park, Y. K., Kim, N. I., Ha, W. K. and Cho, Y. (2010). Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition. 26(9):902–909.
   PubMed Web of Science ®Google Scholar
• Kirkpatrick, C. H., Green, I., Rich, R. R. and Schade, A. L. (1971). Inhibition of growth of Candida albicans by iron-unsaturated lactoferrin: Relation to host-defense mechanisms in chronic mucocutaneous candidiasis. J. Infect. Dis. 124(6):539–544.
   PubMed Web of Science ®Google Scholar
• Legrand, D., Elass, E., Carpentier, M. and Mazurier, J. (2006). Interactions of lactoferrin with cells involved in immune function. Biochem. Cell Biol. 84(3):282–290.
   PubMed Web of Science ®Google Scholar
• Legrand, D., Pierce, A., Elass, E., Carpentier, M., Mariller, C. and Mazurier, J. (2008). Lactoferrin structure and functions. Adv. Exp. Med. Biol. 606:163–194.
   PubMed Web of Science ®Google Scholar
• Leitch, E. C. and Willcox, M. D. (1999). Elucidation of the antistaphylococcal action of lactoferrin and lysozyme. J. Med. Microbiol. 48(9):867–871.
   PubMed Web of Science ®Google Scholar
• Leon-Sicairos, N., Lopez-Soto, F., Reyes-Lopez, M., Godinez-Vargas, D., Ordaz-Pichardo, C. and de la Garza, M. (2006). Amoebicidal activity of milk, apo-lactoferrin, sIgA and lysozyme. Clin. Med. Res. 4(2):106–113.
   PubMedGoogle Scholar
• Lyons, T. E., Miller, M. S., Serena, T., Sheehan, P., Lavery, L., Kirsner, R. S., Armstrong, D. G., Reese, A., Yankee, E. W. and Veves, A. (2007). Talactoferrin alfa, a recombinant human lactoferrin promotes healing of diabetic neuropathic ulcers: A phase 1/2 clinical study. Am. J. Surg. 193(1):49–54.
   PubMed Web of Science ®Google Scholar
• Marchetti, M., Superti, F., Ammendolia, M. G., Rossi, P., Valenti, P. and Seganti, L. (1999). Inhibition of poliovirus type 1 infection by iron-, manganese- and zinc-saturated lactoferrin. Med. Microbiol. Immunol. 187(4):199–204.
   PubMed Web of Science ®Google Scholar
• Mueller, E. A., Trapp, S., Frentzel, A., Kirch, W. and Brantl, V. (2011). Efficacy and tolerability of oral lactoferrin supplementation in mild to moderate acne vulgaris: An exploratory study. Curr. Med. Res. Opin. 27(4):793–797.
   PubMed Web of Science ®Google Scholar
• Ng, T. B., Cheung, R. C., Wong, J. H., Wang, Y., Ip, D. T., Wan, D. C. and Xia, J. (2015). Antiviral activities of whey proteins. Appl. Microbiol. Biotechnol. 99(17):6997–7008.
   PubMed Web of Science ®Google Scholar
• Poulin, Y., Pouliot, Y., Lamiot, E., Aattouri, N. and Gauthier, S. F. (2005). Safety and efficacy of a milk-derived extract in the treatment of plaque psoriasis: An open-label study. J. Cutan. Med. Surg. 9(6):271–275.
   PubMed Web of Science ®Google Scholar
• Saarinen, U. M. and Siimes, M. A. (1977). Iron absorption from infant milk formula and the optimal level of iron supplementation. Acta Paediatr. Scand. 66(6):719–722.
   PubMed Web of Science ®Google Scholar
• Saraceno, R., Gramiccia, T., Chimenti, S., Valenti, P., Pietropaoli, M. and Bianchi, L. (2014). Topical lactoferrin can improve stable psoriatic plaque. G. Ital. Dermatol. Venereol. 149(3):335–340.
   PubMed Web of Science ®Google Scholar
• Schanbacher, F. L., Goodman, R. E. and Talhouk, R. S. (1993). Bovine mammary lactoferrin: Implications from messenger ribonucleic acid (mRNA) sequence and regulation contrary to other milk proteins. J. Dairy Sci. 76(12):3812–3831.
   PubMed Web of Science ®Google Scholar
• Seganti, L., Di Biase, A. M., Marchetti, M., Pietrantoni, A., Tinari, A. and Superti, F. (2004). Antiviral activity of lactoferrin towards naked viruses. Biometals. 17(3):295–299.
   PubMed Web of Science ®Google Scholar
• Siimes, M. A., Salmenpera, L. and Perheentupa, J. (1984). Exclusive breast-feeding for 9 months: Risk of iron deficiency. J. Pediatr. 104(2):196–199.
   PubMed Web of Science ®Google Scholar
• Tursi, A., Elisei, W., Brandimarte, G., Giorgetti, G. M., Modeo, M. E. and Aiello, F. (2007). Effect of lactoferrin supplementation on the effectiveness and tolerability of a 7-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection. Med. Sci. Monit. 13(4):CR187–CR190.
   PubMed Web of Science ®Google Scholar
• Viani, R. M., Gutteberg, T. J., Lathey, J. L. and Spector, S. A. (1999). Lactoferrin inhibits HIV-1 replication in vitro and exhibits synergy when combined with zidovudine. AIDS 13(10):1273–1274.
   PubMed Web of Science ®Google Scholar
• Wakabayashi, H., Uchida, K., Yamauchi, K., Teraguchi, S., Hayasawa, H. and Yamaguchi, H. (2000). Lactoferrin given in food facilitates dermatophytosis cure in guinea pig models. J. Antimicrob. Chemother. 46(4):595–602.
   PubMed Web of Science ®Google Scholar
• Wang, W. P., Iigo, M., Sato, J., Sekine, K., Adachi, I. and Tsuda, H. (2000). Activation of intestinal mucosal immunity in tumor-bearing mice by lactoferrin. Jpn. J. Cancer Res. 91(10):1022–1027.
   PubMedGoogle Scholar
• Wolf, J. S., Li, G., Varadhachary, A., Petrak, K., Schneyer, M., Li, D., Ongkasuwan, J., Zhang, X., Taylor, R. J., Strome, S. E. and O'Malley, B. W. Jr. (2007). Oral lactoferrin results in T cell-dependent tumor inhibition of head and neck squamous cell carcinoma in vivo. Clin. Cancer Res. 13(5):1601–1610.
   PubMed Web of Science ®Google Scholar
• Yalcin, A. S. (2006). Emerging therapeutic potential of whey proteins and peptides. Curr. Pharm. Des. 12(13):1637–1643.
   PubMed Web of Science ®Google Scholar
• Yamauchi, K., Hiruma, M., Yamazaki, N., Wakabayashi, H., Kuwata, H., Teraguchi, S., Hayasawa, H., Suegara, N. and Yamaguchi, H. (2000). Oral administration of bovine lactoferrin for treatment of tinea pedis. A placebo-controlled, double-blind study. Mycoses. 43(5):197–202.
   PubMed Web of Science ®Google Scholar
• Zarember, K. A., Sugui, J. A., Chang, Y. C., Kwon-Chung, K. J. and Gallin, J. I. (2007). Human polymorphonuclear leukocytes inhibit Aspergillus fumigatus conidial growth by lactoferrin-mediated iron depletion. J. Immunol. 178(10):6367–6373.
   PubMed Web of Science ®Google Scholar
• Zimecki, M. and Kruzel, M. L. (2007). Milk-derived proteins and peptides of potential therapeutic and nutritive value. J. Exp. Ther. Oncol. 6(2):89–106.
   PubMedGoogle Scholar