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Lycopene and tomato and risk of cardiovascular diseases: A systematic review and meta-analysis of epidemiological evidence

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References

  • Ascherio, A., et al. 1999. Relation of consumption of vitamin E, vitamin C, and carotenoids to risk for stroke among men in the United States. Ann Intern Med. 130:963–970.
  • Ashor, A. W., et al. 2016. Systematic review and meta-analysis of randomised controlled trials testing the effects of vitamin C supplementation on blood lipids. Clin Nutr. 35:626–637.
  • Bohm, V. 2012. Lycopene and heart health. Mol Nutr Food Res. 56:296–303.
  • Centre for Reviews and Dissemination. 2009. Systematic reviews: CRD's guidance for undertaking reviews in health care. Centre for Reviews and Dissemination: University of York, York, UK.
  • Chen, J., et al. 2013. Lycopene/tomato consumption and the risk of prostate cancer: a systematic review and meta-analysis of prospective studies. J Nutr Sci Vitaminol (Tokyo). 59:213–223.
  • Chen, P., et al. 2015. Lycopene and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis. Medicine (Baltimore). 94:e1260.
  • Cheng, H. M., et al. 2017. Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis. Atherosclerosis. 257:100–108.
  • Dauchet, L., et al. 2006. Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies. J Nutr. 136:2588–2593.
  • Dhurandhar, N. V., et al. 2015. Energy balance measurement: when something is not better than nothing. Int J Obes (Lond). 39:1109–1113.
  • Egger, M., et al. 1997. Bias in meta-analysis detected by a simple, graphical test. Bmj. 315:629–634.
  • Estruch, R., et al. 2013. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 368:1279–1290.
  • Etminan, M., et al. 2004. The role of tomato products and lycopene in the prevention of prostate cancer: a meta-analysis of observational studies. Cancer Epidemiol Biomarkers Prev. 13:340–345.
  • FAOSTAT. 2014. Food Supply - Crops Primary Equivalent [Online]. Food And Agriculture Organization Of The United Nations. Available: http://faostat.fao.org/site/609/DesktopDefault.aspx?PageID=609" \l"ancor" [09 AUG 2016].
  • Fave, G., et al. 2011. Development and validation of a standardized protocol to monitor human dietary exposure by metabolite fingerprinting of urine samples. Metabolomics. 7:469–484.
  • Ford, E. S., et al. 2014. Associations between antioxidants and all-cause mortality among US adults with obstructive lung function. Br J Nutr. 112:1662–1673.
  • Forouzanfar, M. H., et al. 2016. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388:1659–1724.
  • Forouzanfar, M. H., et al. 2015. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet. 386:2287–2323.
  • Hak, A. E., et al. 2004. Prospective study of plasma carotenoids and tocopherols in relation to risk of ischemic stroke. Stroke. 35:1584–1588.
  • Hak, A. E., et al. 2003. Plasma carotenoids and tocopherols and risk of myocardial infarction in a low-risk population of US male physicians. Circulation. 108:802–807.
  • Han, G. M., and X. F. Han. 2016. Lycopene reduces mortality in people with systemic lupus erythematosus: A pilot study based on the third national health and nutrition examination survey. J Dermatolog Treat. 27:430–435.
  • Han, G. M., et al. 2016. Higher levels of serum lycopene are associated with reduced mortality in individuals with metabolic syndrome. Nutr Res. 36:402–407.
  • He, F. J., et al. 2007. Increased consumption of fruit and vegetables is related to a reduced risk of coronary heart disease: meta-analysis of cohort studies. J Hum Hypertens. 21:717–728.
  • He, F. J., et al. 2006. Fruit and vegetable consumption and stroke: meta-analysis of cohort studies. The Lancet. 367:320–326.
  • Higgins, J., and S. Green. 2011. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. In: Cochrane Database Syst Rev.
  • Hirvonen, T., et al. 2000. Intake of flavonoids, carotenoids, vitamins C and E, and risk of stroke in male smokers. Stroke. 31:2301–2306.
  • Hu, D., et al. 2014. Fruits and vegetables consumption and risk of stroke: a meta-analysis of prospective cohort studies. Stroke. 45:1613–1619.
  • Hu, F. B. 2002. Dietary pattern analysis: a new direction in nutritional epidemiology. Curr Opin Lipidol. 13:3–9.
  • Iribarren, C., et al. 1997. Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. A case-control study. The ARIC Study Investigators. Atherosclerosis Risk in Communities. Arterioscler Thromb Vasc Biol. 17:1171–1177.
  • Ito, Y., et al. 2006. Cardiovascular disease mortality and serum carotenoid levels: a Japanese population-based follow-up study. J Epidemiol. 16:154–160.
  • Jacques, P. F., et al. 2013. Relationship of lycopene intake and consumption of tomato products to incident CVD. Br J Nutr. 110:545–551.
  • Kabagambe, E. K., et al. 2005. Some dietary and adipose tissue carotenoids are associated with the risk of nonfatal acute myocardial infarction in Costa Rica. J Nutr. 135:1763–1769.
  • Karppi, J., et al. 2013a. Low levels of plasma carotenoids are associated with an increased risk of atrial fibrillation. Eur J Epidemiol. 28:45–53.
  • Karppi, J., et al. 2013b. Serum beta-carotene concentrations and the risk of congestive heart failure in men: a population-based study. Int J Cardiol. 168:1841–1846.
  • Karppi, J., et al. 2012a. Low serum lycopene and beta-carotene increase risk of acute myocardial infarction in men. Eur J Public Health. 22:835–840.
  • Karppi, J., et al. 2012b. Low beta-carotene concentrations increase the risk of cardiovascular disease mortality among Finnish men with risk factors. Nutr Metab Cardiovasc Dis. 22:921–928.
  • Karppi, J., et al. 2013c. Serum beta-carotene and the risk of sudden cardiac death in men: a population-based follow-up study. Atherosclerosis. 226:172–177.
  • Karppi, J., et al. 2012c. Serum lycopene decreases the risk of stroke in men: a population-based follow-up study. Neurology. 79:1540–1547.
  • Klipstein-Grobusch, K., et al. 2000. Serum carotenoids and atherosclerosis. The Rotterdam Study. Atherosclerosis. 148:49–56.
  • Kohlmeier, L., et al. 1997. Lycopene and myocardial infarction risk in the EURAMIC Study. Am J Epidemiol. 146:618–626.
  • Li, X., and J. Xu. 2014. Dietary and circulating lycopene and stroke risk: a meta-analysis of prospective studies. Sci Rep. 4:5031.
  • Lock, K., et al. 2005. The global burden of disease attributable to low consumption of fruit and vegetables: implications for the global strategy on diet. Bull World Health Organ. 83:100–108.
  • Mayne, S. T., et al. 2004. Low plasma lycopene concentration is associated with increased mortality in a cohort of patients with prior oral, pharynx or larynx cancers. J Am Coll Nutr. 23:34–42.
  • Mein, J. R., et al. 2008. Biological activity of lycopene metabolites: implications for cancer prevention. Nutr Rev. 66:667–683.
  • Moher, D., et al. 2010. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int J Surg. 8:336–341.
  • Mozaffarian, D., et al. 2011. Components of a cardioprotective diet: new insights. Circulation. 123:2870–2891.
  • Ness, A. R., and J. W. Powles. 1997. Fruit and vegetables, and cardiovascular disease: a review. Int J Epidemiol. 26:1–13.
  • Osganian, S. K., et al. 2003. Dietary carotenoids and risk of coronary artery disease in women. American Journal of Clinical Nutrition. 77:1390–1399.
  • Prentice, R. L. 2010. Dietary assessment and the reliability of nutritional epidemiology research reports. J Natl Cancer Inst. 102:583–585.
  • Rissanen, T. H., et al. 2001. Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study. Br J Nutr. 85:749–754.
  • Rosell, M. S., et al. 2003. Associations between diet and the metabolic syndrome vary with the validity of dietary intake data. Am J Clin Nutr. 78:84–90.
  • Satija, A., et al. 2015. Objective measures are complementary to, rather than a replacement for, self-reported methods. Int J Obes (Lond). 39:1179.
  • Sesso, H. D., et al. 2004. Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in women. Am J Clin Nutr. 79:47–53.
  • Sesso, H. D., et al. 2005. Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in men. Am J Clin Nutr. 81:990–997.
  • Sesso, H. D., et al. 2003. Dietary lycopene, tomato-based food products and cardiovascular disease in women. J Nutr. 133:2336–2341.
  • Song, B., et al. 2017. Lycopene and risk of cardiovascular diseases: A meta-analysis of observational studies. Mol Nutr Food Res. 2017 Mar 20. doi: 10.1002/mnfr.201601009. [Epub ahead of print]
  • Souverein, O. W., et al. 2011. Uncertainty in intake due to portion size estimation in 24-hour recalls varies between food groups. J Nutr. 141:1396–1401.
  • Street, D. A., et al. 1994. Serum antioxidants and myocardial infarction. Are low levels of carotenoids and alpha-tocopherol risk factors for myocardial infarction? Circulation. 90:1154–1161.
  • Taubes, G. 1995. Epidemiology faces its limits. Science. 269:164–169.
  • Tavani, A., et al. 2006. Dietary intake of carotenoids and retinol and the risk of acute myocardial infarction in Italy. Free Radic Res. 40:659–664.
  • Trichopoulou, A., et al. 2009. Anatomy of health effects of Mediterranean diet: Greek EPIC prospective cohort study. Bmj. 338:b2337.
  • Wang, H., et al. 2016. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 388:1459–1544.
  • Wood, N., and R. B. Johnson. 2004. The relationship between tomato intake and congestive heart failure risk in periodontitis subjects. J Clin Periodontol. 31:574–580.
  • Yang, T., et al. 2013. The role of tomato products and lycopene in the prevention of gastric cancer: a meta-analysis of epidemiologic studies. Med Hypotheses. 80:383–388.
  • Young, S. S., and A. Karr. 2011. Deming, data and observational studies. Significance. 8:116–120.

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