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Comparison of blood lipid-lowering effects of olive oil and other plant oils: A systematic review and meta‐analysis of 27 randomized placebo‐controlled clinical trials

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References

  • World Health Organisation. 2013. The top 10 causes of death (Fact sheet No. 310). from http://www.who.int/mediacentre/factsheets/fs310/en/.
  • Aguilera, C. M., M. D. Mesa, M. C. Ramirez-Tortosa, M. T. Nestares, E. Ros, and A. Gil. 2004. Sunflower oil does not protect against LDL oxidation as virgin olive oil does in patients with peripheral vascular disease. Clinical Nutrition 23:673–81. doi:10.1016/j.clnu.2003.11.005.
  • Asadi, F., A. Shahriari, and M. Chahardah-Cheric. 2010. Effect of long-term optional ingestion of canola oil, grape seed oil, corn oil and yogurt butter on serum, muscle and liver cholesterol status in rats. Food and Chemical Toxicology 48:2454–7. doi:10.1016/j.fct.2010.06.012.
  • Baltzell, J. K., J. T. Wooten, and D. A. Otto 1991. Lipoprotein lipase in rats fed fish oil: apparent relationship to plasma insulin levels. Lipids 26:289–294. doi:10.1007/BF02537139.
  • Baumstark, M. W., I. Frey, A. Berg, and J. Keul. 1992. Influence of n-3 fatty acids from fish oils on concentration of high- and low-density lipoprotein subfractions and their lipid and apolipoprotein composition. Clinical Biochemistry 25:338–340. doi:10.1016/0009-9120(92)80012-6.
  • Baxheinrich, A., B. Stratmann, Y. H. Lee-Barkey, D. Tschoepe, and U. Wahrburg. 2012. Effects of a rapeseed oil-enriched hypoenergetic diet with a high content of α-linolenic acid on body weight and cardiovascular risk profile in patients with the metabolic syndrome. British Journal of Nutrition 108:682–691. doi:10.1017/S0007114512002875.
  • Berglund, L., M. Lefevre, H. N. Ginsberg, P. M. Kris-Etherton, P. J. Elmer, P. W. Stewart, A. Ershow, T. A. Pearson, B. H. Dennis, P. S. Roheim, R. Ramakrishnan, R. Reed, K. Stewart, and K. M. Phillips. 2007. Comparison of monounsaturated fat with carbohydrates as a replacement for saturated fat in subjects with a high metabolic risk profile: studies in the fasting and postprandial states. American Journal of Clinical Nutrition 86:1611–20.
  • Binkoski, A. E., P. M. Kris-Etherton, T. A. Wilson, M. L. Mountain, and R. J. Nicolosi. 2005. Balance of unsaturated fatty acids is important to a cholesterol-lowering diet: comparison of mid-oleic sunflower oil and olive oil on cardiovascular disease risk factors. Journal of the American Dietetic Association 105:1080–1086. doi:10.1016/j.jada.2005.04.009.
  • Cândido, F. G., F. Xavier Valente, L. E. da Silva, O. G. Leão Coelho, MdC. Gouveia Peluzio, and RdC. Gonçalves Alfenas. 2017. Consumption of extra virgin olive oil improves body composition and blood pressure in women with excess body fat: a randomized, double-blinded, placebo-controlled clinical trial. European Journal of Nutrition 56:1–11. doi:10.1007/s00394-017-1517-9.
  • Castro, P., J. López Miranda, P. Gomez, and D. M. Escalante. 2000. Comparison of an oleic acid enriched-diet vs NCEP-I diet on LDL susceptibility to oxidative modifications. European Journal of Clinical Nutrition 54:61. doi:10.1038/sj.ejcn.1600894.
  • Choudhury, N., L. Tan, and A. Stewart Truswell. 1995. Comparison of palmolein and olive oil: effects on plasma lipids and vitamin E in young adults. The American Journal of Clinical Nutrition 61:1043–1051. doi:10.1093/ajcn/61.5.1043.
  • Chowdhury, R., S. Warnakula, S. Kunutsor, F. Crowe, H. A. Ward, L. Johnson, O. H. Franco, A. S. Butterworth, N. G. Forouhi, and S. G. Thompson. 2014. Association of dietary, circulating, and supplement fatty acids with coronary riska systematic review and meta-analysis. Annals of Internal Medicine 160:398–406. doi:10.7326/M13-1788.
  • Cicero, A. F., and A. Gaddi. 2001. Rice bran oil and gamma-oryzanol in the treatment of hyperlipoproteinaemias and other conditions. Phytotherapy Research 15:277–89. doi:10.1002/ptr.907.
  • Cicero, A. F. G., S. D'addato, A. Fiorito, A. Poli, and A. V. Gaddi. 2009. Plasma lipid effects of corn oil and extra-virgin olive oil in hypercholesterolaemic subjects: a randomised, controlled trial. Mediterranean Journal of Nutrition and Metabolism 1:187–192. doi:10.1007/s12349-008-0028-x.
  • Covas, M. I., R. de la Torre, and M. Fito. 2015. Virgin olive oil: a key food for cardiovascular risk protection. British Journal of Nutrition 113 (Suppl 2):S19–28. doi:10.1017/S0007114515000136.
  • Derouiche, A., M. Cherki, A. Drissi, Y. Bamou, M. El Messal, A. Idrissi-Oudghiri, J. M. Lecerf, and A. Adlouni. 2005. Nutritional intervention study with argan oil in man: effects on lipids and apolipoproteins. Annals of Nutrition & Amp; Metabolism 49:196–201. doi:10.1159/000087072.
  • Drew, B. G., S. J. Duffy, M. F. Formosa, A. K. Natoli, D. C. Henstridge, S. A. Penfold, W. G. Thomas, N. Mukhamedova, B. de Courten, and J. M. Forbes. 2009. High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus. Circulation 119:2103–2111. doi:10.1161/CIRCULATIONAHA.108.843219.
  • Duval, S., and R. Tweedie. 2000. Trim and fill: a simple funnel‐plot–based method of testing and adjusting for publication bias in meta‐analysis. Biometrics 56:455–463. doi:10.1111/j.0006-341X.2000.00455.x.
  • Gillingham, L. G., S. Harris-Janz, and P. J. H. Jones. 2011. Dietary monounsaturated fatty acids are protective against metabolic syndrome and cardiovascular disease risk factors. Lipids 46:209–228. doi:10.1007/s11745-010-3524-y.
  • Griffin, M. E., E. Dimitriadis, K. Lenehan, D. Owens, P. Collins, A. Johnson, and G. H. Tomkin. 1996. Non-insulin-dependent diabetes mellitus: dietary monounsaturated fatty acids and low-density lipoprotein composition and function. Qjm 89:211–6. doi:10.1093/qjmed/89.3.211.
  • Higgins, J. P. T., and S. Green. 2011. Cochrane handbook for systematic reviews of interventions. Version 5.1. 0, Vol. 4. Oxford, England: The Cochrane Collaboration. Available from https://www.cochrane-handbook.org.
  • Hohmann, C.-D., H. Cramer, A. Michalsen, C. Kessler, N. Steckhan, K. Choi, and G. Dobos. 2015. Effects of high phenolic olive oil on cardiovascular risk factors: A systematic review and meta-analysis. Phytomedicine 22:631–640. doi:10.1016/j.phymed.2015.03.019.
  • Huang, C. L., and B. E. Sumpio. 2008. Olive oil, the mediterranean diet, and cardiovascular health. Journal of the American College of Surgeons 207:407–416. doi:10.1016/j.jamcollsurg.2008.02.018.
  • Jantti, J., T. Nikkari, T. Solakivi, H. Vapaatalo, and H. Isomaki. 1989. Evening primrose oil in rheumatoid arthritis: changes in serum lipids and fatty acids. Annals of the Rheumatic Diseases 48:124–7. doi:10.1136/ard.48.2.124.
  • Junker, R., M. Kratz, M. Neufeld, M. Erren, J.-R. Nofer, H. Schulte, U. Nowak-Göttl, G. Assmann, and U. Wahrburg. 2001. Effects of diets containing olive oil, sunflower oil, or rapeseed oil on the hemostatic system. Thrombosis and Haemostasis 85:280–286.
  • Karvonen, H. M., A. Aro, N. S. Tapola, I. Salminen, M. I. J. Uusitupa, and E. S. Sarkkinen. 2002. Effect of [alpha]-linolenic acid [ndash] rich Camelina sativa oil on serum fatty acid composition and serum lipids in hypercholesterolemic subjects. Metabolism-Clinical and Experimental 51:1253–1260. doi:10.1053/meta.2002.35183.
  • Klop, B., J. W. F. Elte, and M. C. Cabezas. 2013. Dyslipidemia in obesity: mechanisms and potential targets. Nutrients 5:1218–1240. doi:10.3390/nu5041218.
  • Kontogianni, M. D., A. Vlassopoulos, A. Gatzieva, A.-E. Farmaki, S. Katsiougiannis, D. B. Panagiotakos, N. Kalogeropoulos, and F. N. Skopouli. 2013. Flaxseed oil does not affect inflammatory markers and lipid profile compared to olive oil, in young, healthy, normal weight adults. Metabolism 62:686–693. doi:10.1016/j.metabol.2012.11.007.
  • Kralova Lesna, I., P. Suchanek, J. Kovar, P. Stavek, and R. Poledne. 2008. Replacement of dietary saturated FAs by PUFAs in diet and reverse cholesterol transport. Journal of Lipid Research 49:2414–8. doi:10.1194/jlr.M800271-JLR200.
  • Kris-Etherton, P. M., T. A. Pearson, Y. Wan, R. L. Hargrove, K. Moriarty, V. Fishell, and T. D. Etherton. 1999. High-monounsaturated fatty acid diets lower both plasma cholesterol and triacylglycerol concentrations. American Journal of Clinical Nutrition 70:1009–15.
  • Kris-Etherton, P. M., J. Derr, D. C. Mitchell, V. A. Mustad, M. E. Russell, E. T. McDonnell, D. Salabsky, and T. A. Pearson. 1993. The role of fatty acid saturation on plasma lipids, lipoproteins, and apolipoproteins: I. Effects of whole food diets high in cocoa butter, olive oil, soybean oil, dairy butter, and milk chocolate on the plasma lipids of young men. Metabolism 42:121–129. doi:10.1016/0026-0495(93)90182-N.
  • Kruse, M., C. von Loeffelholz, D. Hoffmann, A. Pohlmann, A. C. Seltmann, M. Osterhoff, S. Hornemann, O. Pivovarova, S. Rohn, G. Jahreis, and A. F. Pfeiffer. 2015. Dietary rapeseed/canola-oil supplementation reduces serum lipids and liver enzymes and alters postprandial inflammatory responses in adipose tissue compared to olive-oil supplementation in obese men. Molecular Nutrition &Amp; Food Research 59:507–19. doi:10.1002/mnfr.201400446.
  • Lichtenstein, A. H., L. M. Ausman, W. Carrasco, L. J. Gualtieri, J. L. Jenner, J. M. Ordovas, R. J. Nicolosi, B. R. Goldin, and E. J. Schaefer. 1994. Rice bran oil consumption and plasma lipid levels in moderately hypercholesterolemic humans. Arteriosclerosis and Thrombosis 14:549–56. doi:10.1161/01.ATV.14.4.549.
  • Lucci, P., M. Borrero, A. Ruiz, D. Pacetti, N. G. Frega, O. Diez, M. Ojeda, R. Gagliardi, L. Parra, and M. Angel. 2016. Palm oil and cardiovascular disease: a randomized trial of the effects of hybrid palm oil supplementation on human plasma lipid patterns. Food & Function 7:347–54. doi:10.1039/C5FO01083G.
  • Madigan, C., M. Ryan, D. Owens, P. Collins, and G. H. Tomkin. 2000. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 23:1472–7. doi:10.2337/diacare.23.10.1472.
  • Maki, K. C., A. L. Lawless, K. M. Kelley, V. N. Kaden, C. J. Geiger, O. M. Palacios, and M. R. Dicklin. 2017. Corn oil intake favorably impacts lipoprotein cholesterol, apolipoprotein and lipoprotein particle levels compared with extra-virgin olive oil. European Journal of Clinical Nutrition 71:33–38. doi:10.1038/ejcn.2016.169.
  • Martínez-González, M. A., L. J. Dominguez, and M. Delgado-Rodríguez. 2014. Olive oil consumption and risk of CHD and/or stroke: a meta-analysis of case–control, cohort and intervention studies. British Journal of Nutrition 112:248–259. doi:10.1017/S0007114514000713.
  • Mata, P., L. A. Alvarez-Sala, M. J. Rubio, J. Nuño, and M. De Oya 1992. Effects of long-term monounsaturated- vs polyunsaturated-enriched diets on lipoproteins in healthy men and women. The American Journal of Clinical Nutrition 55:846–850. doi:10.1093/ajcn/55.4.846.
  • McNamara, D. J. 1992. Dietary Fatty Acids, Lipoproteins, and Cardiovascular disease. In Advances in Food and Nutrition research36:253–351. doi:10.1016/S1043-4526(08)60107-2.
  • Moher, D., A. Liberati, J. Tetzlaff, D. G. Altman, and P. Group. 2009. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Medicine 6 (7):e1000097. doi:10.1371/journal.pmed.1000097.
  • Namayandeh, S. M., F. Kaseb, and S. Lesan. 2013. Olive and sesame oil effect on lipid profile in hypercholesterolemic patients, which better?. International Journal of Preventive Medicine 4:1059.
  • Nelson, T. L., J. E. Hokanson, and M. S. Hickey. 2011. Omega-3 fatty acids and lipoprotein associated phospholipase A2 in healthy older adult males and females. European Journal of Nutrition 50:185–193. doi:10.1007/s00394-010-0126-7.
  • Nigam, P., S. Bhatt, A. Misra, D. S. Chadha, M. Vaidya, J. Dasgupta, and Q. M. A. Pasha. 2014. Effect of a 6-month intervention with cooking oils containing a high concentration of monounsaturated fatty acids (olive and canola oils) compared with control oil in male Asian Indians with nonalcoholic fatty liver disease. Diabetes Technology & Therapeutics 16:255–261. doi:10.1089/dia.2013.0178.
  • Nydahl, M., I. B. Gustafsson, M. Ohrvall, and B. Vessby. 1995. Similar effects of rapeseed oil (canola oil) and olive oil in a lipid-lowering diet for patients with hyperlipoproteinemia. Journal of the American College of Nutrition 14:643–651. doi:10.1080/07315724.1995.10718554.
  • Ostlund, R. E. Jr, S. B. Racette, and W. F. Stenson. 2002. Effects of trace components of dietary fat on cholesterol metabolism: Phytosterols, oxysterols, and squalene. Nutrition Reviews 60:349–359. doi:10.1301/00296640260385793.
  • Pedersen, A., M. W. Baumstark, P. Marckmann, H. Gylling, and B. Sandstrom. 2000. An olive oil-rich diet results in higher concentrations of LDL cholesterol and a higher number of LDL subfraction particles than rapeseed oil and sunflower oil diets. Journal of Lipid Research 41:1901–11.
  • Perez-Martinez, P., A. Garcia-Rios, J. Delgado-Lista, F. Perez-Jimenez, and J. Lopez-Miranda. 2011. Mediterranean diet rich in olive oil and obesity, metabolic syndrome and diabetes mellitus. Current Pharmaceutical Design 17:769–777. doi:10.2174/138161211795428948.
  • Perona, J. S., J. Canizares, E. Montero, J. M. Sanchez-Dominguez, A. Catala, and V. Ruiz-Gutierrez. 2004. Virgin olive oil reduces blood pressure in hypertensive elderly subjects. Clinical Nutrition 23:1113–21. doi:10.1016/j.clnu.2004.02.004.
  • Plat, J., and R. P. Mensink. 2001. Effects of plant sterols and stanols on lipid metabolism and cardiovascular risk. Nutrition, Metabolism and Cardiovascular Diseases 11:31–40.
  • Poudyal, H., S. K. Panchal, V. Diwan, and L. Brown. 2011. Omega-3 fatty acids and metabolic syndrome: effects and emerging mechanisms of action. Progress in Lipid Research 50:372–87. doi:10.1016/j.plipres.2011.06.003.
  • Roehrich, M.-E., V. Mooser, V. Lenain, J. Herz, J. Nimpf, S. Azhar, M. Bideau, A. Capponi, P. Nicod, and J.-A. Haefliger. 2003. Insulin-secreting β-cell dysfunction induced by human lipoproteins. Journal of Biological Chemistry 278:18368–18375. doi:10.1074/jbc.M300102200.
  • Rozati, M., J. Barnett, D. Wu, G. Handelman, E. Saltzman, T. Wilson, L. Li, J. Wang, A. Marcos, and J. M. Ordovás. 2015. Cardio-metabolic and immunological impacts of extra virgin olive oil consumption in overweight and obese older adults: a randomized controlled trial. Nutrition & Metabolism 12:28. doi:10.1186/s12986-015-0022-5.
  • Mensink, R. P., and M. B. Katan. 1989. Effects of a diet enriched with monounsaturated or polyunsaturated fatty acids on level of low density and high density lipoprotein cholesterol in healthy women and men. The New England Journal of Medicine 321:436–441. doi:10.1056/NEJM198908173210705.
  • Shanmugasundaram, M., S. J. Rough, and J. S. Alpert. 2010. Dyslipidemia in the elderly: should it be treated?. Clinical Cardiology 33:4–9. doi:10.1002/clc.20702.
  • Sirtori, C. R., E. Gatti, E. Tremoli, C. Galli, G. Gianfranceschi, G. Franceschini, S. Colli, P. Maderna, F. Marangoni, and P. Perego. 1992. Olive oil, corn oil, and n-3 fatty acids differently affect lipids, lipoproteins, platelets, and superoxide formation in type II hypercholesterolemia. American Journal of Clinical Nutrition 56:113–22. doi:10.1093/ajcn/56.1.113.
  • Tall, A., E. Granot, R. Brocia, I. Tabas, C. Hesler, K. Williams, and M. Denke. 1987. Accelerated transfer of cholesteryl esters in dyslipidemic plasma. Role of cholesteryl ester transfer protein. Journal of Clinical Investigation 79 (4):1217–25. doi:10.1172/JCI112940.
  • Tanasescu, M., E. Cho, J. E. Manson, and F. B. Hu. 2004. Dietary fat and cholesterol and the risk of cardiovascular disease among women with type 2 diabetes. American Journal of Clinical Nutrition 79:999–1005. doi:10.1093/ajcn/79.6.999.
  • Tholstrup, T., J. Hjerpsted, and M. Raff. 2011. Palm olein increases plasma cholesterol moderately compared with olive oil in healthy individuals. The American Journal of Clinical Nutrition 94:1426–1432. doi:10.3945/ajcn.111.018846.
  • Thomsen, C., H. Storm, J. J. Holst, and K. Hermansen. 2003. Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes. American Journal of Clinical Nutrition 77:605–11. doi:10.1093/ajcn/77.3.605.
  • Trautwein, E. A., D. Rieckhoff, A. Kunath-Rau, and H. F. Erbersdobler. 1999. Replacing saturated fat with PUFA-rich (sunflower oil) or MUFA-rich (rapeseed, olive and high-oleic sunflower oil) fats resulted in comparable hypocholesterolemic effects in cholesterol-fed hamsters. Annals of Nutrition & Amp; Metabolism 43:159–172. doi:10.1159/000012782.
  • Truswell, A. S. 2000. Comparing palmolein with different predominantly monounsaturated oils: effect on plasma lipids. International Journal of Food Sciences and Nutrition 51 (Suppl):S73–7. doi:10.1080/096374800111117.
  • Tzang, B.-S., S.-F. Yang, S.-G. Fu, H.-C. Yang, H.-L. Sun, and Y.-C. Chen. 2009. Effects of dietary flaxseed oil on cholesterol metabolism of hamsters. Food Chemistry 114:1450–1455. doi:10.1016/j.foodchem.2008.11.030.
  • Umesha, S. S., and K. A. Naidu. 2012. Vegetable oil blends with alpha-linolenic acid rich Garden cress oil modulate lipid metabolism in experimental rats. Food Chemistry 135:2845–51. doi:10.1016/j.foodchem.2012.05.118.
  • Wagner, K.-H., R. Tomasch, and I. Elmadfa. 2001. Impact of diets containing corn oil or olive/sunflower oil mixture on the human plasma and lipoprotein lipid metabolism. European Journal of Nutrition 40:161–167. doi:10.1007/s003940170004.
  • Wang, H., A. H. Lichtenstein, S. Lamon-Fava, and P. F. Jacques. 2014. Association between statin use and serum cholesterol concentrations is modified by whole-grain consumption: NHANES 2003–2006. American Journal of Clinical Nutrition 100:1149–57. doi:10.3945/ajcn.113.074344.
  • Xu, J., H. Gao, L. Song, W. Yang, C. Chen, Q. Deng, Q. Huang, J. Yang, and F. Huang. 2013. Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. Lipids in Health and Disease 12:58. doi:10.1186/1476-511X-12-58.

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