Consumption of green coffee and the risk of chronic diseases

References

• Abdel-Wahhab, M. A., H. H. Ahmed, and M. M. Hagazi. 2006. Prevention of aflatoxin B1-initiated hepatotoxicity ın rat by marine algae extracts. Journal of Applied Toxicology 26 (3):229. doi:10.1002/jat.1127.
   PubMed Web of Science ®Google Scholar
• Albertina de Oliveira, N., H. P. Cornelio-Santiago, H. Fukumasu, and A. Lopes de Oliveira. 2018. Green coffee extracts rich in diterpenes – process optimization of pressurized liquid extraction using ethanol as solvent. Journal of Food Engineering 224:148–55. doi:10.1016/j.jfoodeng.2017.12.021.
   Web of Science ®Google Scholar
• Aleksandrova, K., C. Bamia, D. Drogan, P. Lagiou, A. Trichopoulou, M. Jenab, V. Fedirko, I. Romieu, H. B. Bueno-de-Mesquita, and T. Pischon. 2015. The association of coffee intake with liver cancer risk is mediated by biomarkers of inflammation and hepatocellular injury: Data from the European Prospective Investigation into Cancer and Nutrition. The American Journal Of Clinical Nutrition 102 (6):1498–508. doi:10.3945/ajcn.115.116095.
   PubMed Web of Science ®Google Scholar
• Alshatwi, A. A., V. S. Periasamy, J. Athinarayanan, and R. Elango. 2016. Synergistic anticancer activity of dietary tea polyphenols and bleomycin hydrochloride in human cervical cancer cell: Caspase-dependent and independent apoptotic pathways. Chemico-Biological Interactions 247:1–10. doi:10.1016/j.cbi.2016.01.012.
   PubMed Web of Science ®Google Scholar
• Amigo-Benavent, M., S. Wang, R. Mateos, B. Sarri, and L. Bravo. 2017. Antiproliferative and cytotoxic effects of green coffee and yerba mate extracts, their main hydroxycinnamic acids, methylxanthine and metabolites in different human cell lines. Food and Chemical Toxicology 106:125–38. doi:10.1016/j.fct.2017.05.019.
   PubMed Web of Science ®Google Scholar
• Amigoni, L., M. Stuknyte, C. Ciaramelli, C. Magoni, I. Bruni, I. De Noni, C. Airoldi, M. E. Regonesi, and A. Palmioli. 2017. Green coffee extract enhances oxidative stress resistance and delays aging in caenorhabditis elegans. Journal of Functional Foods 33:297–306. doi:10.1016/j.jff.2017.03.056.
   Web of Science ®Google Scholar
• Anderson, K. E. 2004. Effects of specific foods and non-nutritive dietary components on drug metabolism. In Handbook of drug–nutrient interactions eds. J. I. Boullata, V. T. Armenti, 155–73, 1st ed. New Jersey: Humana Press Inc.
   Google Scholar
• Anty, R., S. Marjoux, A. Iannelli, S. Patouraux, A. S. Schneck, and S. Bonnafous. 2012. Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery. Journal of Hepatology 57:1090–96. doi:10.1016/j.jhep.2012.07.014.
   PubMed Web of Science ®Google Scholar
• Arendash, G., T. Mori, C. Cao, M. Mamcarz, M. Runfeldt, and A. Dickson. 2009. Caffeine reverses cognitive impairment and decreases brain Aβ levels in aged Alzheimer's mice. Journal of Alzheimers Disease 17:661–80. doi:10.3233/JAD-2009-1087.
   PubMed Web of Science ®Google Scholar
• Arendash, G. W., and C. Cao. 2010. Caffeine and coffee as therapeutics against Alzhemer's disease. Journal of Alzheimer's Disease 20:117–26. doi:10.3233/JAD-2010-091249.
   PubMed Web of Science ®Google Scholar
• Ascherio, A., M. G. Weisskopf, E. J. O'Reilly, M. L. McCullough, E. E. Calle, and C. Rodriguez. 2004. Coffee consumption, gender, and Parkinson's disease mortality in the cancer prevention study II cohort: the modifying effects of estrogen. American Journal of Epidemiology 160:977–84. doi:10.1093/aje/kwh312.
   PubMed Web of Science ®Google Scholar
• Ayton Global Research, Independent. 2009. Market study on the effect of coffee shape on weight loss, the effect of chlorogenic acid enriched coffee (coffee shape) on weight when used in overweight people. June 2009.
   Google Scholar
• Babova, O., A. Occhipinti, and M. E. Maffei. 2016. Chemical partitioning and antioxidant capacity of green coffee (coffea arabica and coffea canephora) of different geographical origin. Phytochemistry 123:33–39. doi:10.1016/j.phytochem.2016.01.016.
   PubMed Web of Science ®Google Scholar
• Bailey, D. G., G. K. Dresser, B. L. Urquhart, D. J. Freeman, and J. M. Arnold. 2016. Coffee-antihypertensive drug ınteraction: A hemodynamic and pharmacokinetic study with felodipine. American Journal of Hypertension 29 (12):1386–93.
   PubMed Web of Science ®Google Scholar
• Bakuradze, T., N. Boehm, C. Janzowski, R. Lang, T. Hofmann, and J. P. Stockis. 2011. Antioxidant-rich coffee reduces DNA damage, elevates glutathione status and contributes to weight control: Results from an intervention study. Molecular Nutrition & Food Research 55:793–97. doi:10.1002/mnfr.201100093.
   PubMed Web of Science ®Google Scholar
• Banerjee, S., S. Chaudhuri, A. K. Maity, P. Saha, and S. K. Pal. 2014. Role of caffeine in DNA recognition of a potential food carcinogen benzo[a]pyrene and UVA induced DNA damage. Journal of Molecular Recognition 27:510–20. doi:10.1002/jmr.2379.
   PubMed Web of Science ®Google Scholar
• Bech, H. B., E. A. Nohr, M. Vaeth, T. B. Henrikson, and J. Olsen. 2005. Coffee and fetal death: a cohort study of prospective data. American Journal of Epidemiology 168:983–90. doi:10.1093/aje/kwi317.
   Google Scholar
• Blum, J., B. Lemaire, and S. Lafay. 2007. Effect of a green decaffeinated coffee extract on glycaemia. NUTRAfoods 6 (3):13–17.
   Google Scholar
• Bozkurt, B. 2012. Adsorption of Heavy Metal From Wastewaters Using Spent Coffee Grounds. Yıldız Technical University, Graduate School of Natural and Applied Sciences, Master Thesis. 18–24.
   Google Scholar
• Bradbury, A. G. W., and D. J. Halliday. 1990. Chemical structures of green coffee bean polysaccgarides. Journal of Agricultural and Food Chemistry 38 (2):389–92. doi:10.1021/jf00092a010.
   Web of Science ®Google Scholar
• Brahat, N., N. K. Sowmya, and D. S. Mehta. 2015. Determination of antibacterial activity of green coffee bean extract on periodontogenic bacteria like Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans: An in vitro study. Contemporary Clinical Dentistry 6 (2):166–69. doi:10.4103/0976-237X.156036.
   PubMedGoogle Scholar
• Budhathoki, S., M. Iwasaki, T. Yamaji, S. Sasazuki, and S. Tsugane. 2015. Coffee intake and the risk of colorectal adenoma: The colorectal adenoma study in Tokyo. International Journal of Cancer 137 (2):463–70. doi:10.1002/ijc.29390.
   PubMed Web of Science ®Google Scholar
• Budryn, G., E. Nebesny, B. Patecz, D. Rachwał-Rosiak, P. Hodurek, K. Miśkiewicz, J. Oracz, and D. Żyżelewicz. 2014. Inclusion complexes of Β-Cyclodextrin with chlorogenic acids (CGAs) from crude and purified aqueous extracts of green robusta coffee beans (Coffea Canephora L.). Food Research International 61:202–13. doi:10.1016/j.foodres.2013.10.013.
   Web of Science ®Google Scholar
• Budryn, G., D. Zaczyńska, and D. Rachwał-Rosiak. 2016. Changes of free and nanoencapsulated hydroxycinnamic acids from green coffee added to different food products during processing and in vitro enzymatic digestion. Food Research International 89:1004–14. doi:10.1016/j.foodres.2015.12.011.
   Web of Science ®Google Scholar
• Budryn, G., M. Zakłos-Szyda, D. Zaczyńska, D. Żyżelewicz, J. Grzelczyk, Z. Zduńczyk, and J. Juśkiewicz. 2017. Green and roasted coffee extracts as antioxidants in ΒTC3 cells with induced oxidative stress and lipid accumulation inhibitors in 3T3L1 cells, and their bioactivity in rats fed high fat diet. European Food Research and Technology 243:1323–34. doi:10.1007/s00217-017-2843-0.
   Web of Science ®Google Scholar
• Cao, C., L. Wang, X. Lin, M. Mamcarz, C. Zhang, and G. Bai. 2011. Caffeine synergizes with another coffee component to increase plasma GCSF: Linkage to cognitive benefits in Alzheimer's mice. Journal of Alzheimer's Disease 25 (2):323–35.
   Web of Science ®Google Scholar
• Cao, S., L. Liu, X. Yin, Y. Wang, J. Liu, and Z. Lu. 2013. Coffee consumption and risk of prostate cancer: a meta-analysis of prospective cohort studies. Carcinogenesis 25 (2):265–61.
   Google Scholar
• Cárdenas, C., A. R. Quesada, and M. Á. Medina. 2014. Insights on the antitumor effects of kahweol on human breast cancer: Decreased survival and increased production of reactive oxygen species and cytotoxicity. Biochemical and Biophysical Research Communications 447 (3):452–58. doi:10.1016/j.bbrc.2014.04.026.
   PubMed Web of Science ®Google Scholar
• Castro, A. C. C. M., F. B. Oda, M. G. J. Almeida-Cincotto, M. G. Davanço, B. G. Chiari-Andréo, R. M. B. Cicarelli, R. G. Peccinini, G. J. Zocolo, P. R. V. Ribeiro, M. A. Corrêa, et al. 2018. Green coffee seed residue: A sustainable source of antioxidant compounds. Food Chemistry 246:48–57. doi:10.1016/j.foodchem.2017.10.153.
   PubMed Web of Science ®Google Scholar
• Cavin, C., D. Holzhaeuser, G. Scharf, A. Constable, W. W. Huber, and B. Schilter. 2002. Cafestol and kahweol, two coffee specific diterpenes with anticarcinogenic activity. Food and Chemical Toxicology 40:1155–63. doi:10.1016/S0278-6915(02)00029-7.
   PubMed Web of Science ®Google Scholar
• Choi, B. K., S. B. Park, D. R. Lee, H. J. Lee, Y. Y. Jin, S. H. Yang, and J. W. Suh. 2016. Green coffee bean extract improves obesity by decreasing body fat in high-fat diet-induced obese mice. Asian Pacific Journal of Tropical Medicine 9 (7):635–43. doi:10.1016/j.apjtm.2016.05.017.
   PubMed Web of Science ®Google Scholar
• Costa, J., N. Lunet, C. Santos, J. Santos, and A. Vaz-Carneiro. 2010. Caffeine exposure and the risk of Parkinson's disease: a systematic review and meta-analysis of observational studiess. Journal of Alzheimer's Disease 20 (S1):221–38. doi:10.3233/JAD-2010-091525.
   Web of Science ®Google Scholar
• Dellalibera, O., B. Lemaire, and S. Lafay. 2006. Svetol, green coffee extract, induces weight loss and increases the lean to fat mass ratio in volunteers with overweight problem. Phytotherapie 4:1–4.
   Google Scholar
• Ding, M., S. N. Bhupathiraju, M. Chen, R. M. van Dam, and F. B. Hu. 2014. Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis. Diabetes Care 37 (2):569–86. doi:10.2337/dc13-1203.
   PubMed Web of Science ®Google Scholar
• D'hooghe, M. B., P. Haentjes, G. Nagels, and J. De Keyser. 2012. Alcohol, coffee, fish, smoking and disease progression in multiple sclerosis. European Journal of Neurology 19 (4):616–24. doi:10.1111/j.1468-1331.2011.03596.x.
   PubMed Web of Science ®Google Scholar
• Dziki, D., U. Gawlik-Dziki, Ł. Pecio, R. Różyło, M. Świeca, A. Krzykowski, and S. Rudy. 2015. Ground green coffee beans as a functional food supplement – preliminary study. LWT – Food Science and Technology 63 (1):691–99. doi:10.1016/j.lwt.2015.03.076.
   Web of Science ®Google Scholar
• EFSA Panel on Dietetic Products, N., and Allergies. 2011a. Scientific Opinion on the substantiation of health claims related to caffeine and increased fat oxidation leading to a reduction in body fat mass (ID 735, 1484), increased energy expenditure leading to a reduction in body weight (ID 1487), increased alertness (ID 736, 1101, 1187, 1485, 1491, 2063, 2103) and increased attention (ID 736, 1485, 1491, 2375) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal 9 (4):n/a–/a. doi:10.2903/j.efsa.2011.2054.
   Google Scholar
• EFSA Panel on Dietetic Products, N., & Allergies. 2011b. Scientific Opinion on the substantiation of health claims related to coffee, including chlorogenic acids from coffee, and protection of DNA, proteins and lipids from oxidative damage (ID 1099, 3152, 4301), maintenance of normal blood glucose concentrations (ID 1100, 1962), and contribution to the maintenance or achievement of a normal body weight (ID 2031, 4326) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA Journal 9 (4):n/a–/a. doi:10.2903/j.efsa.2011.2057.
   Google Scholar
• EFSA Panel on Dietetic Products, N., & Allergies. 2015. Scientific Opinion on the safety of caffeine. EFSA Journal 13 (5):n/a–/a. doi:10.2903/j.efsa.2015.4102.
   Google Scholar
• Eskelinen, M. H., T. Ngandu, J. Tuomilehto, H. Soininen, and M. Kivipelto. 2009. Midlife coffee and tea drinking and the risk of late-life dementia: A population-based CAIDE study. Journal of Alzheimer's Disease 16 (1):85–91. doi:10.3233/JAD-2009-0920.
   PubMed Web of Science ®Google Scholar
• Farah, A., and C. M. Donangelo. 2006. Phenolic compounds in coffee. Braz Journal of Plant Physiol 18 (1):23–36. doi:10.1590/S1677-04202006000100003.
   Google Scholar
• Farah, A. 2012. Coffee constituents, coffee: Emerging health effects and disease prevention. 21–58.
   Google Scholar
• Ferk, F., W. W. Huber, B. Grasl-Kraupp, K. Speer, S. Buchmann, R. Bohacek, M. Mišík, L. Edelbauer, and S. Knasmüller. 2014. Protective effects of coffee against induction of DNA damage and preneoplastic foci by aflatoxin B1. Mol Nutrition Food Research 58 (2):229–38. doi:10.1002/mnfr.201300154.
   PubMed Web of Science ®Google Scholar
• Fukushima, Y., T. Tashiro, A. Kumagai, H. Ohyanagi, T. Horiuchi, K. Takizawa, N. Sugihara, Y. Kishimoto, C. Taguchi, M. Tani, et al. 2014. Coffee and beverages are the major contributors to polyphenol consumption from food and beverages in Japanese middle-aged women. Journal of Nutritional Science 3, e48:1–10. doi:10.1017/jns.2014.19.
   Google Scholar
• Getachew, A. T., and B. S. Chun. 2016. Influence of hydrothermal process on bioactive compounds extraction from green coffee bean of green coffee extracts: Influence of green coffee bean preparation. Innovative Food Science and Emerging Technologies 38:24–31. doi:10.1016/j.ifset.2016.09.006.
   Web of Science ®Google Scholar
• Gómez-Juaristi, M., S. Martínez-López, B. Sarria, L. Bravo, and R. Raquel Mateos. 2018. Bioavailability of hydroxycinnamates in an instant green/roasted coffee blend in humans. Food Function 9:331–43.
   PubMed Web of Science ®Google Scholar
• Goszcz, K., S. J. Deakin, G. G. Duthie, D. Stewart, S. J. Leslie, and I. L. Megson. 2015. Antioxidants in cardiovascular therapy: panacea or false hope. Frontiers in Cardiovascular Medicine 2 (29):1–22. doi:10.3389/fcvm.2015.00029.
   PubMedGoogle Scholar
• Groessl, E. J., M. A. Allison, J. C. Larson, S. B. Ho, L. G. Snetslaar, D. S. Lane, K. M. Tharp, and M. L. Stefanick. 2016. Coffee consumption and the incidence of colorectal cancer in women. Journal of Cancer Epidemiology 2016:1–8. Article ID: 6918431. doi:10.1155/2016/6918431.
   Google Scholar
• Happonen, P., E. Läärä, L. Hiltunen, and H. Luukinen. 2008. Coffee consumption and mortality in a 14-year follow-up of an elderly northern Finnish population. The British Journal of Nutrition 99 (6):1354–61. doi:10.1017/S0007114507871650.
   PubMed Web of Science ®Google Scholar
• Ho, L., M. Varghese, J. Wang, W. Zhao, F. Chen, L. A. Knable, M. Ferruzzi, and G. M. Pasinetti. 2012. Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice. Nutritional Neuroscience 15 (1):37–45. doi:10.1179/1476830511Y.0000000027.
   PubMed Web of Science ®Google Scholar
• Hoelzl, C., S. Knasmüller, K. H. Wagner, L. Elbling, W. Huber, N. Kager, F. Ferk, V. Ehrlich, A. Nersesyan, O. Neubauer, et al. 2010. Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules. Mol Nutrition Food Research 54:1722–33. doi:10.1002/mnfr.201000048.
   PubMed Web of Science ®Google Scholar
• Hu, G., S. Bidel, P. Jousilahti, R. Antikainen, and J. Tuomilehto. 2007. Coffee and tea consumption and the risk of Parkinson's disease. Movement Disorders 22 (15):2242–48. doi:10.1002/mds.21706.
   PubMed Web of Science ®Google Scholar
• IARC. 2016. IARC Monographs evaluate drinking coffee, mat_e, and very hot beverages. Available from https://www.iarc.fr/en/media-centre/pr/2016/pdfs/pr244_E.pdf.
   Google Scholar
• Iwai, K., Y. Narita, T. Fukunaga, O. Nakagiri, T. Kamiya, M. Ikeguchi, and Y. Kikuchi. 2012. Study on the postprandial glucose responses to a chlorogenic acid-rich extract of decaffeinated green coffee beans in rats and healthy human subjects. Food Science and Technology Research 18 (6):849–60. doi:10.3136/fstr.18.849.
   Web of Science ®Google Scholar
• İştar, B., K. Yapar, A. Acar, E. Yalçın, B. Seven, and K. Çavuşoğlu. 2016. Investigation of protective role of green coffee against genotoxicity ınduced by bisphenol a in albino mice. Cumhuriyet University Faculty of Science Science Journal (CSJ) 37 (4):339–51. doi:10.17776/csj.64101.
   Google Scholar
• Jankiewicz, K., M. Chrościńska-Krawczyk, B. Błaszczyk, and S. J. Czuczwar. 2007. Caffeine and antiepileptic drugs: experimental and clinical data. Przeglad Lekarski 64 (11):965–67.
   PubMedGoogle Scholar
• Jeszka-Skowron, M., A. Sentkowska, K. Pyrzyn´ska, and M. Paz De Peña. 2016a. Chlorogenic acids, caffeine content and antioxidant properties. Eur Food Research Technol 242:1403–9. doi:10.1007/s00217-016-2643-y.
   Web of Science ®Google Scholar
• Jeszka-Skowron, M., E. Stanisz, and M. Paz De Peña. 2016b. Relationship between antioxidant capacity, chlorogenic acids and elemental composition of green coffee. LWT – Food Science and Technology 73:243–50.
   Web of Science ®Google Scholar
• Jeszka-Skowron, M., A. Zgoła-Grze´skowiak, A. Wa´skiewicz, L. Stepien, and E. Stanizs. 2017. Positive and negative aspects of green coffee consumption – antioxidant activity versus mycotoxins. Journal of Sci Food Agric 97:4022–28. doi:10.1002/jsfa.8269.
   PubMed Web of Science ®Google Scholar
• Jiang, W., Y. Wu, and X. Jiang. 2013. Coffee and caffeine intake and breast cancer risk: an updated dose–response meta-analysis of 37 published studies. Gynecologic Oncology 129 (3):620–29. doi:10.1016/j.ygyno.2013.03.014.
   PubMed Web of Science ®Google Scholar
• Kemsley, E. K., S. Ruault, and R. H. Wilson. 1995. Discrimination between Coffea arabica and Coffea canephora variant robusta beans using infrared spectroscopy. Food Chemistry 54 (3):321–26. doi:10.1016/0308-8146(95)00030-M.
   Web of Science ®Google Scholar
• Kleinwächter, M., G. Bytof, and D. Selmar. 2015. Coffee beans and processing. In: Coffee in Health and Disease Prevention, ed. V. R. Preedy, 73–81. San Diego: Academic Press. doi:10.1016/B978-0-12-409517-5.00009-7.
   Google Scholar
• Kozuma, K., S. Tsuchiya, J. Kohori, T. Hase, and I. Tokimitsu. 2005. Antihypertensive effect of green coffee bean extract on mildly hypertensive subjects. Hypertens Research 28 (9):711–18. doi:10.1291/hypres.28.711.
   PubMed Web of Science ®Google Scholar
• Larsson, S. C., and A. Wolk. 2007. Coffee consumption and risk of liver cancer: A meta-analysis. Gastroenterology 132 (5):1740–45. doi:10.1053/j.gastro.2007.03.044.
   PubMed Web of Science ®Google Scholar
• Lee, J. E., D. J. Hunter, D. Spiegelman, H. O. Adami, L. Bernstein, P. A. van den Brandt, J. E. Buring, E. Cho, D. English, A. R. Folsom, et al. 2017. Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies. International Journal of Cancer 121:2246–53. doi:10.1002/ijc.22909.
   Google Scholar
• Li Kwok Cheong, J. D., K. D. Croft, P. D. Henry, V. Matthews, J. M. Hodgson, and N. C. Ward. 2014. Green coffee polyphenols do not attenuate features of the metabolic syndrome and improve endothelial function in mice fed a high fat diet. Archives of Biochemistry and Biophysics 559:46–52. doi:10.1016/j.abb.2014.02.005.
   PubMed Web of Science ®Google Scholar
• Li, X., R. Zhuo, S. Tiong, F. Di Cara, K. King-Jones, S. C. Hughes, S. D. Campbell, and R. Wevrick. 2013. The Smc5/Smc6/MAGE complex confers resistance to caffeine and genotoxic stress in Drosophila melanogaster. PLoS One 8 (3):e59866. doi:10.1371/journal.pone.0059866.
   PubMed Web of Science ®Google Scholar
• Li, X. J., Z. J. Ren, J. W. Qin, J. H. Zhao, J. H. Tang, M. H. Ji, and J. Z. Wu. 2013a. Coffee consumption and risk of breast cancer: an up-to-date meta-analysis. PLoS One 8 (1):e52681. doi:10.1371/journal.pone.0052681.
   PubMed Web of Science ®Google Scholar
• Li, G., D. Ma, Y. Zhang, W. Zheng, and P. Wang. 2013b. Coffee consumption and risk of colorectal cancer: a meta-analysis of observational studies. Public Health Nutrition 16 (02):346–57. doi:10.1017/S1368980012002601.
   PubMed Web of Science ®Google Scholar
• Lindsay, J., D. Laurin, R. Verreault, R. Hébert, B. Helliwell, G. B. Hill, and I. McDowell. 2002. Risk factors for Alzheimer's disease: A prospective analysis from the Canadian Study of Health and Aging. American Journal of Epidemiology 156:445–53. doi:10.1093/aje/kwf074.
   PubMed Web of Science ®Google Scholar
• Liu, H., G. H. Hu, X. C. Wang, T. B. Huang, L. Xu, P. Lai, Z. F. Guo, and Y. F. Xu. 2015. Coffee consumption and prostate cancer risk: A meta-analysis of cohort studies. Nutrition and Cancer 67 (3):392–400. doi:10.1080/01635581.2015.1004727.
   PubMed Web of Science ®Google Scholar
• Lopez-Garcia, E., R. M. van Dam, W. C. Willett, E. B. Rimm, J. E. Manson, M. J. Stampfer, K. M. Rexrode, and F. B. Hu. 2006. Coffee consumption and coronary heart disease in men and women: a prospective cohort study. Circulation 113:2045–53. doi:10.1161/CIRCULATIONAHA.105.598664.
   PubMed Web of Science ®Google Scholar
• Ma, Y., M. Gao, and D. Liu. 2015. Chlorogenic acid improves high fat diet-induced hepatic steatosis and insülin resistance in mice. Pharmaceutical Research 32:1200–9. doi:10.1007/s11095-014-1526-9.
   PubMed Web of Science ®Google Scholar
• Medina-Remán, A., Tresserra-Rimbau A., Valderas-Martinez P., Estruch R., and Lamuela-Raventos R. M. 2014. In Chapter 75 - Polyphenol Consumption and Blood Pressure. Polyphenols in Human Health and Disease, eds. Em R. R. Watson, V. R. Preedy, and S. Zibadi, 971–987. San Diego: Academic Press. doi:10.1016/B978-0-12-398456-2.00075-X.
   Google Scholar
• Minamisawa, M., S. Yoshida, and N. Takai. 2004. Determination of biologically active system. Analytical Science 20:325–28. doi:10.2116/analsci.20.325.
   PubMed Web of Science ®Google Scholar
• Molloy, J. W., C. J. Calcagno, C. D. Williams, F. J. Jones, D. M. Torres, and S. A. Harrison. 2012. Association of coffee and caffeine consumption with fatty liver disease, nonalcoholic steatohepatitis, and degree of hepatic fibrosis. Hepatology 55 (2):429–36. doi:10.1002/hep.24731.
   PubMed Web of Science ®Google Scholar
• Morishita, H., and M. Ohnishi. 2001. Absorption, metabolism and biological activities of chlorogenic acids and related compounds. Studies in Natural Products Chemistry 25:919–53. doi:10.1016/S1572-5995(01)80024-7.
   Google Scholar
• Muley, A., P. Muley, and M. Shah. 2012. Coffee to reduce risk of type 2 diabetes: a systematic review. Current Diabetes Reviews 8 (3):162–68. doi:10.2174/157339912800564016.
   PubMedGoogle Scholar
• Murkovic, M., and K. Derler. 2006. Analysis of amino acids and carbohydrates in green coffee. Journal of Biochemical and Biophysical Methods 69:25–32. doi:10.1016/j.jbbm.2006.02.001.
   PubMedGoogle Scholar
• Narita, Y., and K. Inouye. 2015. Chlorogenic acids from coffee. In Coffee in Health and Disease Prevention, ed. V. Preedy, 189–99. San Diego: Academic Press.
   Google Scholar
• Naveed, M., V. Hejazi, M. Abbas, A. A. Kamboh, G. J. Khan, M. Shumzaid, F. Ahmad, D. Babazadeh, X. Fangfang, F. Modarresi-Ghazani, et al. 2018. Chlorogenic Acid (CGA): A pharmacological review and call for further research. Biomedicine & Pharmacotherapy 97:67–74. doi:10.1016/j.biopha.2017.10.064.
   PubMed Web of Science ®Google Scholar
• Nie, K., Z. Xing, W. Huang, W. Wang, and W. Liu. 2016. Coffee intake and risk of pancreatic cancer: An updated meta-analysis of prospective studies. Minerva Medica 359:270–78.
   Google Scholar
• Nishi, M., S. Ohba, K. Hirata, and H. Miyake. 1996. Dose-response relationship between coffee and the risk of pancreas cancer. Japanese Journal of Clinical Oncology 26 (1):42–48. doi:10.1093/oxfordjournals.jjco.a023177.
   PubMed Web of Science ®Google Scholar
• Nogaim, Q. A., M. Al-Duais, A. Al-Warafi, H. Al-Erianee, and M. Al-Sayadi. 2013. The chemical composition of yemeni green coffee. Journal of Food Chem Nutrition 01 (02):42–48.
   Google Scholar
• Oboh, G., O. B. Ogunsuyi, and O. E. Olonisola. 2017. Does caffeine influence the anticholinesterase and antioxidant properties of donepezil? Evidence from in vitro and in vivo studies. Metabolic Brain Disease 32 (2):629–39. doi:10.1007/s11011-017-9951-1.
   PubMed Web of Science ®Google Scholar
• Ochiai, R., H. Jokura, A. Suzuki, I. Tokimitsu, M. Ohishi, N. Komai, H. Rakugi, and T. Ogihara. 2004. Green coffee bean extract ımproves human vasoreactivity. Hypertens Research 27 (10):731–37. doi:10.1291/hypres.27.731.
   PubMed Web of Science ®Google Scholar
• Oestreich-Janzen, S. 2010. Chemistry of Coffee. In Comprehensive Natural Products II, ed. Mander L and Liu HW, vol. 3:1085–17. Germany: Elsevier B.V. doi:10.1016/B978-008045382-8.00708-5.
   Google Scholar
• Olthof, M. R., P. C. Hollman, P. L. Zock, and M. B. Katan. 2001. Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans. The American Journal of Clinical Nutrition 73:532–38. doi:10.1093/ajcn/73.3.532.
   PubMed Web of Science ®Google Scholar
• Onakpoya, I., R. Terry, and E. Ernst. 2011. The use of green coffee extract as a weight loss supplement: A systematic review and meta-analysis of randomised clinical trials. Gastroenterology Research and Practice 2011:1–6. doi:10.1155/2011/382852.
   Web of Science ®Google Scholar
• Park, G. H., H. M. Song, and J. B. Jeong. 2016. The coffee diterpene kahweol suppresses the cell proliferation by inducing cyclin D1 proteasomal degradation via ERK1/2, JNK and GKS3β-dependent threonine-286 phosphorylation in human colorectal cancer cells. Food and Chemical Toxicology 95:142–48. doi:10.1016/j.fct.2016.07.008.
   PubMed Web of Science ®Google Scholar
• Peron, G., D. Santarossa, D. Voinovich, S. Dall'Acqua, and S. Sut. 2018. Urine metabolomics shows an induction of fatty acids metabolism in healthy adult volunteers after supplementation with green coffee (Coffea robusta L.) bean extract. Phytomedicine 38 (1):74–83. doi:10.1016/j.phymed.2017.11.002.
   PubMedGoogle Scholar
• Perrone, D., C. Marino Donangelo, and A. Farah. 2008. Fast simultaneous analysis of caffeine, trigonelline, nicotinic acid and sucrose in coffee by liquid chromatography–mass spectrometry. Food Chemistry 110 (4):1030–35. doi:10.1016/j.foodchem.2008.03.012.
   PubMed Web of Science ®Google Scholar
• Petrick, J. L., N. D. Freedman, B. I. Graubard, V. V. Sahasrabuddhe, G. Y. Lai, M. C. Alavanja, L. E. Beane-Freeman, D. A. Boggs, J. E. Buring, A. T. Chan, et al. 2015. Coffee consumption and risk of hepatocellular carcinoma and intrahepatic cholangiocarcinoma by sex: The Liver Cancer Pooling Project. Cancer Epidemiology Biomarkers & Prevention 24 (9):1398–406. doi:10.1158/1055-9965.EPI-15-0137.
   PubMed Web of Science ®Google Scholar
• Priftis, A., E. M. Panagiotou, K. Lakis, C. Plika, M. Halabalaki, G. Ntasi, A. S. Veskoukis, D. Stagos, L. A. Skaltsounis, and D. Kouretas. 2018. Roasted and green coffee extracts show antioxidant and cytotoxic activity in myoblast and endothelial cell lines in a cell specific manner. Food and Chemical Toxicology 114:119–27. doi:10.1016/j.fct.2018.02.029.
   PubMed Web of Science ®Google Scholar
• Ran, H. Q., J. Z. Wang, and C. Q. Sun. 2016. Coffee consumption and pancreatic cancer risk: An update meta-analysis of cohort studies. Pakistan Journal of Medical Sciences 32 (1):253–59.
   PubMed Web of Science ®Google Scholar
• Renehan, A. G., D. L. Roberts, and C. Dive. 2008. Obesity and cancer: Pathophysiological and biological mechanisms. Archives of Physiology and Biochemistry 114 (1):71–83. doi:10.1080/13813450801954303.
   PubMedGoogle Scholar
• Revuelta-Iniesta, R., and E. A. S. Al-Dujaili. 2014. Consumption of green coffee reduces blood pressure and body composition by ınfluencing 11β-HSD1 enzyme activity in healthy ındividuals: A pilot crossover study using green and black coffee. BioMed Research International Volume 2014: 1–9. Article ID: 482704. doi.org/10.1155/2014/482704.
   Google Scholar
• Rodriguez de Sotillo, D. V., and M. Hadley. 2002. Chlorogenic acid modifies plasma, liver concentrations of: Cholesterol, triacylglycerol, and minerals in (fa/fa) Zucker rats. Journal of Nutritional Biochemistry 13:717–26. doi:10.1016/S0955-2863(02)00231-0.
   PubMed Web of Science ®Google Scholar
• Sääksjärvi, K., P. Knekt, H. Rissanen, M. A. Laaksonen, A. Reunanen, and S. Männistö. 2008. Prospective study of the coffee consumption and risk of Parkinson's disease. European Journal of Clinical Nutrition 62 (7):908–15. doi:10.1038/sj.ejcn.1602788.
   PubMed Web of Science ®Google Scholar
• Schmit, S. L., H. S. Rennert, G. Rennert, and S. B. Gruber. 2016. Coffee consumption and the risk of colorectal cancer. Cancer Epidemiology Biomarkers & Prevention 25 (4):634–39. doi:10.1158/1055-9965.EPI-15-0924.
   PubMed Web of Science ®Google Scholar
• Świeca, M., U. Gawlik-Dziki, D. Dziki, and B. Baraniak. 2017. Wheat bread enriched with green coffee -In vitro bioaccessibility and bioavailability of phenolics and antioxidant activity. Food Chemistry 221:1451–57. doi:10.1016/j.foodchem.2016.11.006.
   PubMed Web of Science ®Google Scholar
• Sarriá, B., S. Martínez-López, R. Mateos, and L. Bravo-Clemente. 2016. Long-term consumption of a green/roasted coffee blend positively affects glucose metabolism and insulin resistance in humans. Food Research International 89:1023–28. doi:10.1016/j.foodres.2015.12.032.
   Web of Science ®Google Scholar
• Sarriá, B., S. Martínez-López, J. L. Sierra-Cinos, L. García-Diz, R. Mateos, and L. Bravo-Clemente. 2018. Regularly consuming a green/roasted coffee blend reduces the risk of metabolic syndrome. Eur Journal of Nutrition 57:269–78. doi:10.1007/s00394-016-1316-8.
   PubMed Web of Science ®Google Scholar
• Schilter, B., C. Cavin, A. Tritscher, and A. Constable. 2001. Health effects and safety considerations. In Coffee RecentDevelopments, eds. R. J. Clarke, O. G. Vitzthum, 165–83. Oxford: Agricultural Series; Blackwell Publishing Ltd.
   Google Scholar
• Seczyk, L., M. Świeca, and U. Gawlik-Dziki. 2017. Soymilk enriched with green coffee phenolics -antioxidant and nutritional properties in the light of phenolics-food matrix interactions. Food Chemistry 223:1–7. doi:10.1016/j.foodchem.2016.12.020.
   PubMed Web of Science ®Google Scholar
• Setiawan, V. W., L. R. Wilkens, S. C. Lu, B. Y. Hernandez, L. Le Marchand, and B. E. Henderson. 2015. Association of coffee intake with reduced incidence of liver cancer and death from chronic liver disease in the US multiethnic cohort. Gastroenterology 148 (1):118–25. doi:10.1053/j.gastro.2014.10.005.
   PubMed Web of Science ®Google Scholar
• Shahmohammadi, H. A., S. A. Hosseini, E. Hajiani, A. S. Malehi, and M. Alipour. 2017. Effects of green coffee bean extract supplementation on patients with non-alcoholic fatty liver disease: A randomized clinical trial. Hepatitis Monthly 17 (4):e45609.1–9. doi:10.5812/hepatmon.45609.
   Web of Science ®Google Scholar
• Shearer, J. I., A. Farah, T. I. de Paulis, D. P. Bracy, R. R. Pencek, T. E. Graham, and D. H. Wasserman. 2003. Quinides of roasted coffee enhance insulin action in conscious rats. Journal of Nutrition 133 (11):3529–32. doi:10.1093/jn/133.11.3529.
   PubMed Web of Science ®Google Scholar
• Shimoda, H., E. Seki, and M. Aitani. 2006. Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice. BMC Complementary and Alternative Medicine 6:1–9. doi:10.1186/1472-6882-6-9.
   Google Scholar
• Song, S. J., S. Choi, and T. Park. 2014. Decaffeinated green coffee bean extract attenuates diet-ınduced obesity and ınsulin resistance in mice. Evidence-Based Complementary and Alternative Medicine 2014:1–14. Article ID: 718379. https://doi.org/10.1155/2014/718379.
   Web of Science ®Google Scholar
• Stelmach, E., P. Pohl, and A. S. Madeja. 2015. The content of Ca, Cu, Fe, Mg and Mn and antioxidant activity of green coffee brews. Food Chemistry 182:302–8. doi:10.1016/j.foodchem.2015.02.105.
   PubMed Web of Science ®Google Scholar
• Suárez-Quiroz, M., W. Taillefer, E. M. López Méndez, O. González‐Ríos, P. Villeneuve, and M. C. Figueroa-Espinoza. 2013. Antibacterial activity and antifungal and anti-mycotoxigenic activities against Aspergıllus flavus and A. ochraceus of green coffee chlorogenic acids and dodecyl chlorogenate. Journal of Food Safety 33:360–68. doi:10.1111/jfs.12060.
   Web of Science ®Google Scholar
• Szopa, A., E. Poleszak, E. Wyska, A. Serefko, S. Wośko, A. Wlaź, M. Pieróg, A. Wróbel, and P. Wlaź. 2016. Caffeine enhances the antidepressant-like activity of common antidepressant drugs in the forced swim test in mice. Naunyn-Schmiedeberg's Archives of Pharmacology 389 (2):211–21. doi:10.1007/s00210-015-1189-z.
   PubMed Web of Science ®Google Scholar
• Şemen, S., S. Mercan, M. Yayla, and M. Açıkkol. 2017. Elemental composition of green coffee and its contribution to dietary intake. Food Chemistry 215:92–100. doi:10.1016/j.foodchem.2016.07.176.
   PubMed Web of Science ®Google Scholar
• Tajik, N., M. Tajik, I. Mack, and P. Enck. 2017. The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: A comprehensive review of the literature. Eur Journal of Nutrition 56:2215–44. doi:10.1007/s00394-017-1379-1.
   PubMed Web of Science ®Google Scholar
• Tchekalarova, J., H. Kubová, and P. Mareš. 2013. Effects of caffeine on cortical epileptic afterdisCGArges in adult rats are modulated by postnatal treatment. Acta Neurologica Belgica 113 (4):493–500. doi:10.1007/s13760-013-0233-3.
   PubMed Web of Science ®Google Scholar
• Thom, E. 2007. The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and ıts effect on body mass when used long-term in overweight and obese people. The Journal of International Medical Research 35:900–908. doi:10.1177/147323000703500620.
   PubMed Web of Science ®Google Scholar
• Tverdal, A. 2015. Boiled coffee consumption and the risk of prostate cancer: follow-up of 224,234 Norwegian men 20–69 years. British Journal of Cancer 112 (3):576–79. doi:10.1038/bjc.2014.645.
   PubMed Web of Science ®Google Scholar
• van Dam, R. M., and F. B. Hu. 2005. Coffee consumption and risk of type 2 diabetes: A systematic review. JAMA 294 (1):97–104. doi:10.1001/jama.294.1.97.
   PubMed Web of Science ®Google Scholar
• van Gelder, B. M., B. Buijsse, M. Tijhuis, S. Kalmijn, S. Giampaoli, A. Nissinen, and D. Kronhout. 2007. Coffee consumption is inversely associated with cognitive decline in elderly European men: The FINE Study. European Journal of Clinical Nutrition 61 (2):226–32. doi:10.1038/sj.ejcn.1602495.
   PubMed Web of Science ®Google Scholar
• Vucic, E. A., C. J. Brown, and W. L. Lam. 2008. Epigenetics of cancer progression. Pharmacogenomics 9:215–34. doi:10.2217/14622416.9.2.215.
   PubMed Web of Science ®Google Scholar
• Watanabe, T., Y. Arai, Y. Mitsui, T. Kusaura, W. Okawa, Y. Kajihara, and I. Saito. 2006. The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension. Clinical and Experimental Hypertension 28 (5):439–49. doi:10.1080/10641960600798655.
   PubMed Web of Science ®Google Scholar
• Wei, F., and M. Tanokura. 2015. Organic compounds in green coffee beans. Coffee in Health and Disease Prevention 149–62. doi:10.1016/B978-0-12-409517-5.00017-6.
   Google Scholar
• Wierzejska, R. 2012. Caffeine – Common ıngredient in a diet and ıts ınfluence on human health. Roczniki Panstwowego Zakladu Higieny 63 (2):141–47.
   PubMedGoogle Scholar
• Wilson, K. M., J. L. Kasperzyk, J. R. Rider, S. Kenfield, R. M. van Dam, M. J. Stampfer, E. Giovannucci, and L. A. Mucci. 2011. Coffee consumption and prostate cancer risk and progression in the Health Professionals Follow-up Study. Journal of the National Cancer Institute 103 (11):876–84. doi:10.1093/jnci/djr151.
   PubMedGoogle Scholar
• Wolska, J., K. Janda, K. Jakubczyk, M. Szymkowiak, D. Chlubek, and I. Gutowska. 2017. Levels of antioxidant activity and fluoride content in coffee ınfusions of arabica, robusta and green coffee beans in according to their brewing methods. Biology Trace Element Resources 179:2–3. doi:10.1007/s12011-017-0963-9.
   Web of Science ®Google Scholar
• Yamada, H., M. Kawado, N. Aoyama, S. Hashimoto, K. Suzuki, K. Wakai, S. Suzuki, Y. Watanabe, A. Tamakoshi, and J. S. Group. 2014. Coffee consumption and risk of colorectal cancer: The Japan Collaborative Cohort Study. Journal of Epidemiology 24 (5):370–78. doi:10.2188/jea.JE20130168.
   PubMed Web of Science ®Google Scholar
• Yamaguchi, T., A. Chikama, K. Mori, T. Watanabe, Y. Shioya, Y. Katsuragi, and I. Tokimitsu. 2008. Hydroxyhydroquinone-free coffee: a double-blind, randomized controlled doseresponse study of blood pressure. Nutrition, Metabolism and Cardiovascular Diseases 18 (6):408–14. doi:10.1016/j.numecd.2007.03.004.
   PubMed Web of Science ®Google Scholar
• Yu, X., Z. Bao, J. Zou, and J. Dong. 2011. Coffee consumption and risk of cancers: a meta-analysis of cohort studies. BMC Cancer 11:96. 1–14. doi:10.1186/1471-2407-11-96.
   PubMed Web of Science ®Google Scholar
• Yüceşen, D. 2012. The determination of usage opportunities in various fields of spent coffee grounds. Master Thesis, Yıldız Technical University, Graduate School of Natural and Applied Sciences, İstanbul.
   Google Scholar
• Zain, M. Z. M., A. S. Baba, and A. B. Shori. 2017. Effect of polyphenols enriched from green coffee bean on antioxidant activity and sensory evaluation of bread. Journal of King Saud University-Science 30:278–82. https://doi.org/10.1016/j.jksus.2017.12.003.
   Google Scholar