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Encapsulation of cinnamaldehyde: an insight on delivery systems and food applications

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References

  • Abdelmalek, I., A. Mesli, I. Svahn, and G. Simonneaux. 2017. Cinnamaldehyde loaded-microparticles obtained by complex coacervation: Influence of the process parameters on the morphology and the release of the core material. Biointerface Research in Applied Chemistry 7:1939–44.
  • Agrimonti, C., J. C. White, S. Tonetti, and N. Marmiroli. 2019. Antimicrobial activity of cellulosic pads amended with emulsions of essential oils of oregano, thyme and cinnamon against microorganisms in minced beef meat. International Journal of Food Microbiology 305:108246.
  • Akbarbaglu, Z., S. H. Peighambardoust, K. Sarabandi, and S. M. Jafari. 2021. Spray drying encapsulation of bioactive compounds within protein-based carriers; different options and applications. Food Chemistry 359:129965. doi:10.1016/j.foodchem.2021.129965.
  • Amiri, E., M. Aminzare, H. H. Azar, and M. R. Mehrasbi. 2019. Combined antioxidant and sensory effects of corn starch films with nanoemulsion of Zataria multiflora essential oil fortified with cinnamaldehyde on fresh ground beef patties. Meat Science 153:66–74. doi: 10.1016/j.meatsci.2019.03.004.
  • Aungtikun, J., M. Soonwera, and S. Sittichok. 2021. Insecticidal synergy of essential oils from Cymbopogon citratus (Stapf.), Myristica fragrans (Houtt.), and Illicium verum Hook. f. and their major active constituents. Industrial Crops and Products 164:113386. doi: 10.1016/j.indcrop.2021.113386.
  • Bangham, A. D., M. M. Standish, and J. C. Watkins. 1965. Diffusion of univalent ions across the lamellae of swollen phospholipids. Journal of Molecular Biology 13 (1):238–52. doi: 10.1016/s0022-2836(65)80093-6.
  • Bashiri, S., B. Ghanbarzadeh, A. Ayaseh, J. Dehghannya, and A. Ehsani. 2020a. Preparation and characterization of chitosan-coated nanostructured lipid carriers (CH-NLC) containing cinnamon essential oil for enriching milk and anti-oxidant activity. LWT - Food Science and Technology 119:108836. doi: 10.1016/j.lwt.2019.108836.
  • Bashiri, S., B. Ghanbarzadeh, A. Ayaseh, J. Dehghannya, A. Ehsani, and H. Ozyurt. 2020b. Essential oil-loaded nanostructured lipid carriers: The effects of liquid lipid type on the physicochemical properties in beverage models. Food Bioscience 35:100526. doi: 10.1016/j.fbio.2020.100526.
  • Brasil, I. M., C. Gomes, A. Puerta-Gomez, M. E. Castell-Perez, and R. G. Moreira. 2012. Polysaccharide-based multilayered antimicrobial edible coating enhances quality of fresh-cut papaya. LWT - Food Science and Technology 47 (1):39–45. doi: 10.1016/j.lwt.2012.01.005.
  • Cadena, M. B., G. M. Preston, R. A. L. Van der Hoorn, N. A. Flanagan, H. E. Townley, and I. P. Thompson. 2018. Enhancing cinnamon essential oil activity by nanoparticle encapsulation to control seed pathogens. Industrial Crops and Products 124:755–64. doi: 10.1016/j.indcrop.2018.08.043.
  • Cao, T. L., and K. B. Song. 2020. Development of bioactive Bombacaceae gum films containing cinnamon leaf essential oil and their application in packaging of fresh salmon fillets. LWT - Food Science and Technology 131:109647. doi: 10.1016/j.lwt.2020.109647.
  • Carvalho, R. L., M. F. Cabral, T. A. Germano, W. M. de Carvalho, I. M. Brasil, M. I. Gallão, C. F. H. Moura, M. M. A. Lopes, and M. R. A. de Miranda. 2016. Chitosan coating with trans-cinnamaldehyde improves structural integrity and antioxidant metabolism of fresh-cut melon. Postharvest Biology and Technology 113:29–39. doi: 10.1016/j.postharvbio.2015.11.004.
  • Cevallos, P. A. P., M. Buera, and B. E. Elizalde. 2010. Encapsulation of cinnamon and thyme essential oils components (cinnamaldehyde and thymol) in β-cyclodextrin: Effect of interactions with water on complex stability. Journal of Food Engineering 99 (1):70–5. doi: 10.1016/j.jfoodeng.2010.01.039.
  • Chaudhari, A. K., A. K. Dwivedy, V. K. Singh, S. Das, A. Singh, and N. K. Dubey. 2019. Essential oils and their bioactive compounds as green preservatives against fungal and mycotoxin contamination of food commodities with special reference to their nanoencapsulation. Environmental Science and Pollution Research International 26 (25):25414–31. doi: 10.1007/s11356-019-05932-2.
  • Chaudhari, V. K. S., V. K. Singh, S. Das, and N. K. Dubey. 2021. Nanoencapsulation of essential oils and their bioactive constituents: A novel strategy to control mycotoxin contamination in food system. Food and Chemical Toxicology 149:112019. doi: 10.1016/j.fct.2021.112019.
  • Chen, W., F. Cheng, C. J. Swing, S. Xia, and X. Zhang. 2019. Modulation effect of core-wall ratio on the stability and antibacterial activity of cinnamaldehyde liposomes. Chemistry and Physics of Lipids 223:104790. doi: 10.1016/j.chemphyslip.2019.104790.
  • Chuesiang, P., R. Sanguandeekul, and U. Siripatrawan. 2020a. Phase inversion temperature-fabricated cinnamon oil nanoemulsion as a natural preservative for prolonging shelf-life of chilled Asian seabass (Lates calcarifer) fillets. LWT - Food Science and Technology 125:109122. doi: 10.1016/j.lwt.2020.109122.
  • Chuesiang, P., R. Sanguandeekul, and U. Siripatrawan. 2020b. Enhancing effect of nanoemulsion on antimicrobial activity of cinnamon essential oil against foodborne pathogens in refrigerated Asian seabass (Lates calcarifer) fillets. Food Control 122:107782. doi: 10.1016/j.foodcont.2020.107782.
  • Chuesiang, P., U. Siripatrawan, R. Sanguandeekul, L. McLandsborough, and D. J. McClements. 2018. Optimization of cinnamon oil nanoemulsions using phase inversion temperature method: Impact of oil phase composition and surfactant concentration. Journal of Colloid and Interface Science 514:208–16. doi: 10.1016/j.jcis.2017.11.084.
  • Chuesiang, P., U. Siripatrawan, R. Sanguandeekul, J. S. Yang, D. J. McClements, and L. McLandsborough. 2019. Antimicrobial activity and chemical stability of cinnamon oil in oil-in-water nanoemulsions fabricated using the phase inversion temperature method. LWT-Food Science and Technology 110:190–6. doi: 10.1016/j.lwt.2019.03.012.
  • Coimbra, P. P. S., F. S. N. Cardoso, and E. Gonçalves. 2020. Spray-drying wall materials: Relationship with bioactive compounds. Critical Reviews in Food Science and Nutrition, 1–18. doi: 10.1080/10408398.2020.1786354.
  • Cortés-Morales, E. A., G. Mendez-Montealvo, and G. Velazquez. 2021. Interactions of the molecular assembly of polysaccharide-protein systems as encapsulation materials. A review . Advances in Colloid and Interface Science 295:102398. doi: 10.1016/j.cis.2021.102398.
  • Crucho, C. I. C., and M. T. Barros. 2017. Polymeric nanoparticles: A study on the preparation variables and characterization methods. Materials Science and Engineering: C 80:771–84. doi: 10.1016/j.msec.2017.06.004.
  • Cui, H., W. Li, C. Li, S. Vittayapadung, and L. Lin. 2016. Liposome containing cinnamon oil with antibacterial activity against methicillin-resistant Staphylococcus aureus biofilm. Biofouling 32 (2):215–25. doi: 10.1080/08927014.2015.1134516.
  • Dávila-Rodríguez, M., A. López-Malo, E. Palou, N. Ramírez-Corona, and M. T. Jiménez-Munguía. 2019. Antimicrobial activity of nanoemulsions of cinnamon, rosemary, and oregano essential oils on fresh celery. LWT - Food Science and Technology 112:108247. doi: 10.1016/j.lwt.2019.06.014.
  • de Aquino, A. B., A. F. Blank, and L. C. Santana. 2015. Impact of edible chitosan-cassava starch coatings enriched with Lippia gracilis Schauer genotype mixtures on the shelf life of guavas (Psidium guajava L.) during storage at room temperature. Food Chemistry 171:108–16. doi: 10.1016/j.foodchem.2014.08.077.
  • Delshadi, R., A. Bahrami, A. G. Tafti, F. J. Barba, and L. L. Williams. 2020. Micro and nano-encapsulation of vegetable and essential oils to develop functional food products with improved nutritional profiles. Trends in Food Science & Technology 104:72–83. doi: 10.1016/j.tifs.2020.07.004.
  • de Kruif, C. G., F. Weinbreck, and R. de Vries. 2004. Complex coacervation of proteins and anionic polysaccharides. Current Opinion in Colloid & Interface Science 9 (5):340–9. doi: 10.1016/j.cocis.2004.09.006.
  • Donsi, F., M. Annunziata, M. Vincensi, and G. Ferrari. 2012. Design of nanoemulsion-based delivery systems of natural antimicrobials: Effect of the emulsifier. Journal of Biotechnology 159 (4):342–50. doi: 10.1016/j.jbiotec.2011.07.001.
  • Donsi, F., and G. Ferrari. 2016. Essential oil nanoemulsions as antimicrobial agents in food. Journal of Biotechnology 233:106–20. doi: 10.1016/j.jbiotec.2016.07.005.
  • Fadel, H. H. M., A. H. El-Ghorab, A. M. S. Hussein, K. F. El-Massry, S. N. Lotfy, M. Y. S. Ahmed, and T. N. Soliman. 2020. Correlation between chemical composition and radical scavenging activity of 10 commercial essential oils: Impact of microencapsulation on functional properties of essential oils. Arabian Journal of Chemistry 13 (8):6815–27. doi: 10.1016/j.arabjc.2020.06.034.
  • Fadel, H. H. M., I. M. Hassan, M. T. Ibraheim, M. A. A. El Mageed, and R. Saad. 2019. Effect of using cinnamon oil encapsulated in maltodextrin as exogenous flavouring on flavour quality and stability of biscuits. Journal of Food Science and Technology 56 (10):4565–74. doi: 10.1007/s13197-019-03931-2.
  • Faikoh, E. N., Y. H. Hong, and S. Y. Hu. 2014. Liposome-encapsulated cinnamaldehyde enhances zebrafish (Danio rerio) immunity and survival when challenged with Vibrio vulnificus and Streptococcus agalactiae. Fish & Shellfish Immunology 38 (1):15–24. doi: 10.1016/j.fsi.2014.02.024.
  • Fernández-Pan, I., X. Carrión-Granda, and J. I. Maté. 2014. Antimicrobial efficiency of edible coatings on the preservation of chicken breast fillets. Food Control 36 (1):69–75. doi: 10.1016/j.foodcont.2013.07.032.
  • Ferreyra Maillard, A. P. V., J. C. Espeche, P. Maturana, A. C. Cutro, and A. Hollmann. 2021. Zeta potential beyond materials science: Applications to bacterial systems and to the development of novel antimicrobials. Biochimica et Biophysica Acta. Biomembranes 1863 (6):183597. doi: 10.1016/j.bbamem.2021.183597.
  • Friedman, M. 2017. Chemistry, antimicrobial mechanisms, and antibiotic activities of cinnamaldehyde against pathogenic bacteria in animal feeds and human foods. Journal of Agricultural and Food Chemistry 65 (48):10406–23. doi: 10.1021/acs.jafc.7b04344.
  • Geranpour, M., E. Assadpour, and S. M. Jafari. 2020. Recent advances in the spray drying encapsulation of essential fatty acids and functional oils. Trends in Food Science & Technology 102:71–90.
  • Gong, C., M. C. Lee, M. Godec, Z. Zhang, and A. Abbaspourrad. 2020. Ultrasonic encapsulation of cinnamon flavor to impart heat stability for baking applications. Food Hydrocolloids 99:105316. doi: 10.1016/j.foodhyd.2019.105316.
  • Gouda, A., O. S. Sakr, M. Nasr, and O. Sammour. 2021. Ethanol injection technique for liposomes formulation: An insight into development, influencing factors, challenges and applications. Journal of Drug Delivery Science and Technology 61:102174. doi: 10.1016/j.jddst.2020.102174.
  • Guo, C., M. Zhang, and S. Devahastin. 2020. Color/aroma changes of 3D-printed buckwheat dough with yellow flesh peach as triggered by microwave heating of gelatin-gum Arabic complex coacervates. Food Hydrocolloids 112:106358. doi: 10.1016/j.foodhyd.2020.106358.
  • Guo, X., B. Chen, X. Wu, J. Li, and Q. Sun. 2020. Utilization of cinnamaldehyde and zinc oxide nanoparticles in a carboxymethylcellulose-based composite coating to improve the postharvest quality of cherry tomatoes. International Journal of Biological Macromolecules 160:175–82. doi: 10.1016/j.ijbiomac.2020.05.201.
  • Herrera, A., F. J. Rodriguez, J. E. Bruna, R. L. Abarca, M. J. Galotto, A. Guarda, C. Mascayano, C. Sandoval-Yanez, M. Padula, and F. R. Felipe. 2019. Antifungal and physicochemical properties of inclusion complexes based on β-cyclodextrin and essential oil derivatives. Food Research International 121:127–35. doi: 10.1016/j.foodres.2019.03.026.
  • Hilbig, J., Q. Ma, P. M. Davidson, J. Weiss, and Q. Zhong. 2016. Physical and antimicrobial properties of cinnamon bark oil co-nanoemulsified by lauric arginate and Tween 80. International Journal of Food Microbiology 233:52–9. doi: 10.1016/j.ijfoodmicro.2016.06.016.
  • Hill, L. E., C. Gomes, and T. M. Taylor. 2013. Characterization of beta-cyclodextrin inclusion complexes containing essential oils (trans-cinnamaldehyde, eugenol, cinnamon bark, and clove bud extracts) for antimicrobial delivery applications. LWT - Food Science and Technology 51 (1):86–93. doi: 10.1016/j.lwt.2012.11.011.
  • Hu, J., Y. Zhang, Z. Xiao, and X. Wang. 2018. Preparation and properties of cinnamon-thyme-ginger composite essential oil nanocapsules. Industrial Crops and Products 122:85–92. doi: 10.1016/j.indcrop.2018.05.058.
  • Ifeduba, E. A., and C. C. Akoh. 2015. Microencapsulation of stearidonic acid soybean oil in complex coacervates modified for enhanced stability. Food Hydrocolloids 51:136–45. doi: 10.1016/j.foodhyd.2015.05.008.
  • Istúriz-Zapata, M. A., M. Hernández-López, Z. N. Correa-Pacheco, and L. L. Barrera-Necha. 2020. Quality of cold-stored cucumber as affected by nanostructured coatings of chitosan with cinnamon essential oil and cinnamaldehyde. LWT - Food Science and Technology 123:109089. doi: 10.1016/j.lwt.2020.109089.
  • Ji, M., X. Sun, X. Guo, W. Zhu, J. Wu, L. Chen, J. Wang, M. Chen, C. Cheng, and Q. Zhang. 2019. Green synthesis, characterization and in vitro release of cinnamaldehyde/sodium alginate/chitosan nanoparticles. Food Hydrocolloids 90:515–22. doi: 10.1016/j.foodhyd.2018.12.027.
  • Jiang, J., M. P. Emont, H. Jun, X. Qiao, J. Liao, D. Kim, and J. Wu. 2017. Cinnamaldehyde induces fat cell-autonomous thermogenesis and metabolic reprogramming. Metabolism: clinical and Experimental 77:58–64. doi: 10.1016/j.metabol.2017.08.006.
  • Jiang, Y., D. Wang, F. Li, D. Li, and Q. Huang. 2020. Cinnamon essential oil Pickering emulsion stabilized by zein-pectin composite nanoparticles: Characterization, antimicrobial effect and advantages in storage application. International Journal of Biological Macromolecules 148:1280–9. doi: 10.1016/j.ijbiomac.2019.10.103.
  • Jiménez, M., J. A. Domínguez, L. A. Pascual-Pineda, E. Azuara, and C. I. Beristain. 2018. Elaboration and characterization of O/W cinnamon (Cinnamomum zeylanicum) and black pepper (Piper nigrum) emulsions. Food Hydrocolloids 77:902–10. doi: 10.1016/j.foodhyd.2017.11.037.
  • Jo, Y.-J., J.-Y. Chun, Y.-J. Kwon, S.-G. Min, G.-P. Hong, and M.-J. Choi. 2015. Physical and antimicrobial properties of trans-cinnamaldehyde nanoemulsions in water melon juice. LWT - Food Science and Technology 60 (1):444–51. doi: 10.1016/j.lwt.2014.09.041.
  • Joukar, F., S. M. H. Hosseini, M. Moosavi-Nasab, G. R. Mesbahi, and A. Behzadnia. 2017. Effect of Farsi gum-based antimicrobial adhesive coatings on the refrigeration shelf life of rainbow trout fillets. LWT - Food Science and Technology 80:1–9. doi: 10.1016/j.lwt.2017.01.074.
  • Ju, J., X. Chen, Y. Xie, H. Yu, Y. Guo, Y. Cheng, H. Qian, and W. Yao. 2019. Application of essential oil as a sustained release preparation in food packaging. Trends in Food Science & Technology 92:22–32. doi: 10.1016/j.tifs.2019.08.005.
  • Ju, J., Y. Xie, Y. Guo, Y. Cheng, H. Qian, and W. Yao. 2019. Application of edible coating with essential oil in food preservation. Critical Reviews in Food Science and Nutrition 59 (15):2467–80. doi: 10.1080/10408398.2018.1456402.
  • Ju, J., Y. Xie, Y. Guo, Y. Cheng, H. Qian, and W. Yao. 2020. Application of starch microcapsules containing essential oil in food preservation. Critical Reviews in Food Science and Nutrition 60 (17):2825–36. doi: 10.1080/10408398.2018.1503590.
  • Khanniri, E., N. Bagheripoor-Fallah, S. Sohrabvandi, A. M. Mortazavian, K. Khosravi-Darani, and R. Mohammad. 2016. Application of liposomes in some dairy products. Critical Reviews in Food Science and Nutrition 56 (3):484–93. doi: 10.1080/10408398.2013.779571.
  • Kharat, M., and D. J. McClements. 2019. Recent advances in colloidal delivery systems for nutraceuticals: A case study—Delivery by design of curcumin. Journal of Colloid and Interface Science 557:506–18. doi: 10.1016/j.jcis.2019.09.045.
  • Kumar, A., V. Gupta, P. P. Singh, A. Kujur, and B. Prakash. 2020. Fabrication of volatile compounds loaded-chitosan biopolymer nanoparticles: Optimization, characterization and assessment against Aspergillus flavus and aflatoxin B1 contamination. International Journal of Biological Macromolecules 165 (Pt A):1507–18. doi: 10.1016/j.ijbiomac.2020.09.257.
  • Leitgeb, M., Ž. Knez, and M. Primožič. 2020. Sustainable technologies for liposome preparation. The Journal of Supercritical Fluids 165:104984.
  • Li, M., C. Du, N. Guo, Y. Teng, X. Meng, H. Sun, S. Li, P. Yu, and H. Galons. 2019. Composition design and medical application of liposomes. European Journal of Medicinal Chemistry 164:640–53. doi: 10.1016/j.ejmech.2019.01.007.
  • Liu, M., L. Xu, W. Liu, J. Yu, G. Jing, and L. Hai. 2020. Cinnamaldehyde regulates the synthesis of Alternaria alternata non-hostselective toxins by influencing PKS gene expression and oxidoreductase activity. Industrial Crops and Products 145:112074. doi: 10.1016/j.indcrop.2019.112074.
  • Liu, Q., H. Cui, B. Muhoza, E. Duhoranimana, S. Xia, K. Hayat, S. Hussain, M. U. Tahir, and X. Zhang. 2020. Fabrication of low environment-sensitive nanoparticles for cinnamaldehyde encapsulation by heat-induced gelation method. Food Hydrocolloids 105:105789. doi: 10.1016/j.foodhyd.2020.105789.
  • Low, L. E., S. P. Siva, Y. K. Ho, E. S. Chan, and B. T. Tey. 2020. Recent advances of characterization techniques for the formation, physical properties and stability of pickering emulsion. Advances in Colloid and Interface Science 277:102117.
  • Mao, L., Y. H. Roos, C. G. Biliaderis, and S. Miao. 2017. Food emulsions as delivery systems for flavor compounds: A review. Critical Reviews in Food Science and Nutrition 57 (15):3173–87. doi: 10.1080/10408398.2015.1098586.
  • McClements, D. J. 2007. Critical review of techniques and methodologies for characterization of emulsion stability. Critical Reviews in Food Science and Nutrition 47 (7):611–49. doi: 10.1080/10408390701289292.
  • McClements, D. J. 2010. Emulsion design to improve the delivery of functional lipophilic components. Annual Review of Food Science and Technology 1:241–69. doi: 10.1146/annurev.food.080708.100722.
  • McClements, D. J. 2012. Nanoemulsions versus microemulsions: Terminology, differences, and similarities. Soft Matter 8 (6):1719–29. doi: 10.1039/C2SM06903B.
  • McClements, D. J. 2018. Encapsulation, protection, and delivery of bioactive proteins and peptides using nanoparticle and microparticle systems: A review. Advances in Colloid and Interface Science 253:1–22. doi: 10.1016/j.cis.2018.02.002.
  • McClements, D. J., and S. M. Jafari. 2018. Improving emulsion formation, stability and performance using mixed emulsifiers: A review. Advances in Colloid and Interface Science 251:55–79. doi: 10.1016/j.cis.2017.12.001.
  • McDaniel, A., B. Tonyali, U. Yucel, and V. Trinetta. 2019. Formulation and development of lipid nanoparticle antifungal packaging films to control postharvest disease. Journal of Agriculture and Food Research 1:100013. doi: 10.1016/j.jafr.2019.100013.
  • Moghimi, R., A. Aliahmadi, and H. Rafati. 2017. Ultrasonic nanoemulsification of food grade trans-cinnamaldehyde: 1,8-Cineol and investigation of the mechanism of antibacterial activity. Ultrasonics Sonochemistry 35 (Pt A):415–21. doi: 10.1016/j.ultsonch.2016.10.020.
  • Muhammad, D. R. A., A. Sedaghat Doost, V. Gupta, M. D. B. Sintang, D. V. de Walle, P. V. der Meeren, and K. Dewettinck. 2020. Stability and functionality of xanthan gum–shellac nanoparticles for the encapsulation of cinnamon bark extract. Food Hydrocolloids 100:105377. doi: 10.1016/j.foodhyd.2019.105377.
  • Muhoza, B., S. Xia, J. Cai, X. Zhang, E. Duhoranimana, and J. Su. 2019. Gelatin and pectin complex coacervates as carriers for cinnamaldehyde: Effect of pectin esterification degree on coacervate formation, and enhanced thermal stability. Food Hydrocolloids 87:712–22. doi: 10.1016/j.foodhyd.2018.08.051.
  • Muhoza, B., S. Xia, X. Wang, and X. Zhang. 2020. The protection effect of trehalose on the multinuclear microcapsules based on gelatin and high methyl pectin coacervate during freeze-drying. Food Hydrocolloids 105:105807. doi: 10.1016/j.foodhyd.2020.105807.
  • Muhoza, B., S. Xia, X. Wang, X. Zhang, Y. Li, and S. Zhang. 2020. Microencapsulation of essential oils by complex coacervation method: Preparation, thermal stability, release properties and applications. Critical Reviews in Food Science and Nutrition, 1–20. doi: 10.1080/10408398.2020.1843132.
  • Mura, P. 2015. Analytical techniques for characterization of cyclodextrin complexes in the solid state: A review. Journal of Pharmaceutical and Biomedical Analysis 113:226–38. doi: 10.1016/j.jpba.2015.01.058.
  • Nazari, M., H. Majdi, M. Milani, S. Abbaspour-Ravasjani, H. Hamishehkar, and L. Lim. 2019. Cinnamon nanophytosomes embedded electrospun nanofiber: Its effects on microbial quality and shelf-life of shrimp as a novel packaging. Food Packaging and Shelf Life 21:100349. doi: 10.1016/j.fpsl.2019.100349.
  • Noghabi, S. M., and M. Molaveisi. 2020. The effect of wall formulation on storage stability and physicochemical properties of cinnamon essential oil microencapsulated by spray drying. Chemical Papers 74 (10):3455–65. doi: 10.1007/s11696-020-01171-9.
  • Olmedo, R. H., C. M. Asensio, and N. R. Grosso. 2015. Thermal stability and antioxidant activity of essential oils from aromatic plants farmed in Argentina. Industrial Crops and Products 69:21–8. doi: 10.1016/j.indcrop.2015.02.005.
  • Otoni, C. G., M. R. de Moura, F. A. Aouada, G. P. Camilloto, R. S. Cruz, M. V. Lorevice, NdFF. Soares, and L. H. C. Mattoso. 2014. Antimicrobial and physical-mechanical properties of pectin/papaya puree/cinnamaldehyde nanoemulsion edible composite films. Food Hydrocolloids 41:188–94. doi: 10.1016/j.foodhyd.2014.04.013.
  • Paris, M. J., N. Ramírez-Corona, E. Palou, and A. Lopez-Malo. 2020. Modelling release mechanisms of cinnamon (Cinnamomum zeylanicum) essential oil encapsulated in alginate beads during vapor-phase application. Journal of Food Engineering 282:110024. doi: 10.1016/j.jfoodeng.2020.110024.
  • Pateiro, M., P. E. S. Munekata, A. S. Sant’Ana, R. Domínguez, D. Rodríguez-Lázaro, and J. M. Lorenzo. 2021. Application of essential oils as antimicrobial agents against spoilage and pathogenic microorganisms in meat products. International Journal of Food Microbiology 337:108966. doi: 10.1016/j.ijfoodmicro.2020.108966.
  • Pattni, B. S., V. V. Chupin, and V. P. Torchilin. 2015. New developments in liposomal drug delivery. Chemical Reviews 115 (19):10938–66. doi: 10.1021/acs.chemrev.5b00046.
  • Paudel, S. K., K. Bhargava, and H. Kotturi. 2019. Antimicrobial activity of cinnamon oil nanoemulsion against Listeria monocytogenes and Salmonella spp. on melons. LWT - Food Science and Technology 111:682–7. doi: 10.1016/j.lwt.2019.05.087.
  • Pistone, S., M. Rykke, G. Smistad, and M. Hiorth. 2017. Polysaccharide-coated liposomal formulations for dental targeting. International Journal of Pharmaceutics 516 (1-2):106–15. doi: 10.1016/j.ijpharm.2016.11.028.
  • Praseptiangga, D., S. E. Invicta, and L. U. Khasanah. 2019. Sensory and physicochemical characteristics of dark chocolate bar with addition of cinnamon (Cinnamomum burmannii) bark oleoresin microcapsule. Journal of Food Science and Technology 56 (9):4323–32. doi: 10.1007/s13197-019-03901-8.
  • Prata, A. S., and C. R. F. Grosso. 2015. Influence of the oil phase on the microencapsulation by complex coacervation. Journal of the American Oil Chemists’ Society 92 (7):1063–72. doi: 10.1007/s11746-015-2670-z.
  • Pongsumpun, P., S. Iwamoto, and U. Siripatrawan. 2020. Response surface methodology for optimization of cinnamon essential oil nanoemulsion with improved stability and antifungal activity. Ultrasonics Sonochemistry 60:104604. doi: 10.1016/j.ultsonch.2019.05.021.
  • Qiu, C., C. Wang, C. Gong, D. J. McClements, Z. Jin, and J. Wang. 2020. Advances in research on preparation, characterization, interaction with proteins, digestion and delivery systems of starch-based nanoparticles. International Journal of Biological Macromolecules 152:117–25. doi: 10.1016/j.ijbiomac.2020.02.156.
  • Raeisi, M., A. Tabaraei, M. Hashemi, and N. Behnampour. 2016. Effect of sodium alginate coating incorporated with nisin, Cinnamomum zeylanicum, and rosemary essential oils on microbial quality of chicken meat and fate of Listeria monocytogenes during refrigeration. International Journal of Food Microbiology 238:139–45. doi: 10.1016/j.ijfoodmicro.2016.08.042.
  • Rai, V. K., N. Mishra, K. S. Yadav, and N. P. Yadav. 2018. Nanoemulsion as pharmaceutical carrier for dermal and transdermal drug delivery: Formulation development, stability issues, basic considerations and applications. Journal of Controlled Release 270:203–25. doi: 10.1016/j.jconrel.2017.11.049.
  • Rao, J., B. Chen, and D. J. McClements. 2019. Improving the efficacy of essential oils as antimicrobials in foods: Mechanisms of action. Annual Review of Food Science and Technology 10:365–87. doi: 10.1146/annurev-food-032818-121727.
  • Reineccius, G. A. 2004. The spray drying of food flavors. Drying Technology 22 (6):1289–324. doi: 10.1081/DRT-120038731.
  • Ribes, S., A. Fuentes, P. Talens, and J. M. Barat. 2017. Application of cinnamon bark emulsions to protect strawberry jam from fungi. LWT - Food Science and Technology 78:265–72. doi: 10.1016/j.lwt.2016.12.047.
  • Sahraee, S., J. M. Milani, J. M. Regenstein, and H. S. Kafil. 2019. Protection of foods against oxidative deterioration using edible films and coatings: A review. Food Bioscience 32:100451. doi: 10.1016/j.fbio.2019.100451.
  • Salvia-Trujillo, L., R. Soliva-Fortuny, M. A. Rojas-Grau, D. J. McClements, and O. Martin-Belloso. 2017. Edible nanoemulsions as carriers of active ingredients: A review. Annual Review of Food Science and Technology 8:439–66. doi: 10.1146/annurev-food-030216-025908.
  • Sampath, C., J. G. Sprouse, M. L. Freeman, and P. R. Gangula. 2019. Activation of Nrf2 attenuates delayed gastric emptying in obesity induced diabetic (T2DM) female mice. Free Radical Biology and Medicine 135:132–43. doi: 10.1016/j.freeradbiomed.2019.02.029.
  • Samrot, A. V., T. C. Sean, T. Kudaiyappan, U. Bisyarah, A. Mirarmandi, E. Faradjeva, A. Abubakar, H. H. Ali, J. L. A. Angalene, and S. S. Kumar. 2020. Production, characterization and application of nanocarriers made of polysaccharides, proteins, bio-polyesters and other biopolymers: A review. International Journal of Biological Macromolecules 165 (Pt B):3088–105. doi: 10.1016/j.ijbiomac.2020.10.104.
  • Santiago-Adame, R., L. Medina-Torres, J. A. Gallegos-Infante, F. Calderas, R. F. González-Laredo, N. E. Rocha-Guzmán, L. A. Ochoa-Martínez, and M. J. B. Bernad. 2015. Spray drying-microencapsulation of cinnamon infusions (Cinnamomum zeylanicum) with maltodextrin. LWT - Food Science and Technology 64 (2):571–7. doi: 10.1016/j.lwt.2015.06.020.
  • Santo, I. E., R. Campardelli, E. C. Albuquerque, S. V. de Melo, G. Della Porta, and E. Reverchon. 2014. Liposomes preparation using a supercritical fluid assisted continuous process. Chemical Engineering Journal 249:153–9. doi: 10.1016/j.cej.2014.03.099.
  • Sedaghat Doost, A., K. Dewettinck, F. Devlieghere, and P. V. der Meeren. 2018. Influence of non-ionic emulsifier type on the stability of cinnamaldehyde nanoemulsions: A comparison of polysorbate 80 and hydrophobically modified inulin. Food Chemistry 258:237–44. doi: 10.1016/j.foodchem.2018.03.078.
  • Sedaghat Doost, A., M. N. Nasrabadi, V. Kassozi, H. Nakisozi, and P. V. der Meeren. 2020. Recent advances in food colloidal delivery systems for essential oils and their main components. Trends in Food Science & Technology 99:474–86. doi: 10.1016/j.tifs.2020.03.037.
  • Seshadri, V. D., B. Balamuralikrishnan, N. A. Al-Dhabi, G. A. Esmail, and M. V. Arasu. 2020. Essential oils of Cinnamomum loureirii and Evolvulus alsinoides protect guavafruits from spoilage bacteria, fungi and insect (Pseudococcus longispinus). Industrial Crops and Products 154:112629. doi: 10.1016/j.indcrop.2020.112629.
  • Sessa, G., and G. Weissmann. 1970. Incorporation of lysozyme into liposomes. A model for structure-linked latency. Journal of Biological Chemistry 245 (13):3295–301. doi: 10.1016/S0021-9258(18)62994-1.
  • Shao, P., J. Feng, P. Sun, N. Xiang, B. Lu, and D. Qiu. 2020. Recent advances in improving stability of food emulsion by plant polysaccharides. Food Research International 137:109376. doi: 10.1016/j.foodres.2020.109376.
  • Shao, P., Y. Liu, C. Ritzoulis, and B. Niu. 2019. Preparation of zein nanofibers with cinnamaldehyde encapsulated in surfactants at critical micelle concentration for active food packaging. Food Packaging and Shelf Life 22:100385. doi: 10.1016/j.fpsl.2019.100385.
  • Shaozhi, Z., L. Jielin, C. Guangming, and W. Qin. 2018. Thermodynamic analysis of a freeze-dryer utilizing hygroscopic solution. Drying Technology 36 (6):697–708. doi: 10.1080/07373937.2017.1308952.
  • Shreaz, S., W. A. Wani, J. M. Behbehani, V. Raja, M. Irshad, M. Karched, I. Ali, W. A. Siddiqi, and L. T. Hun. 2016. Cinnamaldehyde and its derivatives, a novel class of antifungal agents. Fitoterapia 112:116–31. doi: 10.1016/j.fitote.2016.05.016.
  • Smaoui, S., A. B. Hsouna, A. Lahmar, K. Ennouri, A. Mtibaa-Chakchouk, I. Sellem, S. Najah, M. Bouaziz, and L. Mellouli. 2016. Bio-preservative effect of the essential oil of the endemicMentha piperita used alone and in combination with BacTN635 in stored minced beef meat. Meat Science 117:196–204. doi: 10.1016/j.meatsci.2016.03.006.
  • Souza, C. J. F., and E. E. Garcia-Rojas. 2015. Effects of salt and protein concentrations on the association and dissociation of ovalbumin-pectin complexes. Food Hydrocolloids 47:124–9. doi: 10.1016/j.foodhyd.2015.01.010.
  • Steiner, B. M., D. J. McClements, and G. Davidov-Pardo. 2018. Encapsulation systems for lutein: A review. Trends in Food Science & Technology 82:71–81. doi: 10.1016/j.tifs.2018.10.003.
  • Sun, Q., J. Li, Y. Sun, Q. Chen, L. Zhang, and T. Le. 2020. The antifungal effects of cinnamaldehyde against Aspergillus niger and its application in bread preservation. Food Chemistry 317:126405. doi: 10.1016/j.foodchem.2020.126405.
  • Sun, Q., P. Tang, L. Zhao, H. Pu, Y. Zhai, and H. Li. 2018. Mechanism and structure studies of cinnamaldehyde/cyclodextrins inclusions by computer simulation and NMR technology. Carbohydrate Polymers 194:294–302. doi: 10.1016/j.carbpol.2018.04.055.
  • Sun, Q., L. Wang, Z. Lu, and Y. Liu. 2015. In vitro anti-aflatoxigenic effect and mode of action of cinnamaldehyde against aflatoxin B1. International Biodeterioration & Biodegradation 104:419–25. doi: 10.1016/j.ibiod.2015.07.009.
  • Taha, A., E. Ahmed, A. Ismaiel, M. Ashokkumar, X. Xu, S. Pan, and H. Hu. 2020. Ultrasonic emulsification: An overview on the preparation of different emulsifiers-stabilized emulsions. Trends in Food Science & Technology 105:363–77. doi: 10.1016/j.tifs.2020.09.024.
  • Tang, W., C. Zou, C. Da, Y. Cao, and H. Peng. 2020. A review on the recent development of cyclodextrin-based materials used in oilfield applications. Carbohydrate Polymers 240:116321. doi: 10.1016/j.carbpol.2020.116321.
  • Tarhini, M., H. Greige-Gerges, and A. Elaissari. 2017. Protein-based nanoparticles: From preparation to encapsulation of active molecules. International Journal of Pharmaceutics 522 (1-2):172–97. doi: 10.1016/j.ijpharm.2017.01.067.
  • Tran, V. V., J. Y. Moon, and Y. C. Lee. 2019. Liposomes for delivery of antioxidants in cosmeceuticals: Challenges and development strategies. Journal of Controlled Release 300:114–40. doi: 10.1016/j.jconrel.2019.03.003.
  • Volkova, T. V., and G. L. Perlovich. 2020. Comparative analysis of solubilization and complexation characteristics for new antifungal compound with cyclodextrins. Impact of cyclodextrins on distribution process. European Journal of Pharmaceutical Sciences 154:105531. doi: 10.1016/j.ejps.2-020.105531.
  • Wang, X., F. Cheng, X. Wang, T. Feng, S. Xia, and X. Zhang. 2021. Chitosan decoration improves the rapid and long-term antibacterial activities of cinnamaldehyde-loaded liposomes. International Journal of Biological Macromolecules 168:59–66. doi: 10.1016/j.ijbiomac.2020.12.003.
  • Wang, X., L. Liu, S. Xia, B. Muhoza, J. Cai, X. Zhang, E. Duhoranimana, and J. Su. 2019. Sodium carboxymethyl cellulose modulates the stability of cinnamaldehyde-loaded liposomes at high ionic strength. Food Hydrocolloids 93:10–18. doi: 10.1016/j.foodhyd.2019.02.004.
  • Wang, X., C. J. Swing, T. Feng, S. Xia, J. Yu, and X. Zhang. 2019. Effects of environmental pH and ionic strength on the physical stability of cinnamaldehyde-loaded liposomes. Journal of Dispersion Science and Technology 41 (10):1568. doi: 10.1080/01932691.2019.1627887.
  • Wang, Y., Y. Xia, P. Zhang, L. Ye, L. Wu, and S. He. 2017. Physical characterization and pork packaging application of chitosan films incorporated with combined essential oils of cinnamon and ginger. Food and Bioprocess Technology 10 (3):503–11. doi: 10.1007/s11947-016-1833-8.
  • Wu, J., H. Liu, S. Ge, S. Wang, Z. Qin, L. Chen, Q. Zheng, Q. Liu, and Q. Zhang. 2015. The preparation, characterization, antimicrobial stability and in vitro release evaluation of fish gelatin films incorporated with cinnamon essential oil nanoliposomes. Food Hydrocolloids 43:427–35. doi: 10.1016/j.foodhyd.2014.06.017.
  • Xiong, W., Q. Deng, J. Li, B. Li, and Q. Zhong. 2020. Ovalbumin-carboxymethylcellulose complex coacervates stabilized high internal phase emulsions: Comparison of the effects of pH and polysaccharide charge density. Food Hydrocolloids 98:105282. doi: 10.1016/j.foodhyd.2019.105282.
  • Xu, J., L. Zhou, J. Miao, W. Yu, L. Zou, W. Zhou, C. Liu, and W. Liu. 2020. Effect of cinnamon essential oil nanoemulsion combined with ascorbic acid on enzymatic browning of cloudy apple juice. Food and Bioprocess Technology 13 (5):860–70. doi: 10.1007/s11947-020-02443-8.
  • Xu, L., N. Tao, W. Yang, and G. Jing. 2018. Cinnamaldehyde damaged the cell membrane of Alternaria alternata and induced the degradation of mycotoxins in vivo. Industrial Crops and Products 112:427–433. doi: 10.1016/j.indcrop.2017.12.038.
  • Yeh, H., C. Luo, C. Lin, S. Cheng, Y. Hsu, and S. Chang. 2013. Methods for thermal stability enhancement of leaf essential oils and their main constituents from indigenous cinnamon (Cinnamomum osmophloeum). Journal of Agricultural and Food Chemistry 61 (26):6293–8. doi: 10.1021/jf401536y.
  • Yildirim, S. T., M. H. Oztop, and Y. Soyer. 2017. Cinnamon oil nanoemulsions by spontaneous emulsification: Formulation, characterization and antimicrobial activity. LWT - Food Science and Technology 84:122–28. doi: 10.1016/j.lwt.2017.05.041.
  • Yildiz, Z. I., M. E. Kilic, E. Durgun, and T. Uyar. 2019. Molecular encapsulation of cinnamaldehyde within cyclodextrin inclusion complex electrospun nanofibers: Fast-dissolution, enhanced water solubility, high temperature stability, and antibacterial activity of cinnamaldehyde. Journal of Agricultural and Food Chemistry 67 (40):11066–76. doi: 10.1021/acs.jafc.9b02789.
  • Zhang, L., F. Critzer, P. M. Davidson, and Q. Zhong. 2014. Formulating essential oil microemulsions as washing solutions for organic fresh produce production. Food Chemistry 165:113–8. doi: 10.1016/j.foodchem.2014.05.115.
  • Zhang, S., M. Zhang, Z. Fang, and Y. Liu. 2017. Preparation and characterization of blended cloves/cinnamon essential oil nanoemulsions. LWT - Food Science and Technology 75:316–22. doi: 10.1016/j.lwt.2016.08.046.
  • Zhang, T., J. Xu, Y. Zhang, X. Wang, J. M. Lorenzo, and J. Zhong. 2020. Gelatins as emulsifiers for oil-in-water emulsions: Extraction, chemical composition, molecular structure, and molecular modification. Trends in Food Science & Technology 106:113–31. doi: 10.1016/j.tifs.2020.10.005.
  • Zhao, H., J. Yuan, Q. Yang, Y. Xie, W. Cao, and S. Wang. 2015. Cinnamaldehyde in a novel intravenous submicrometer emulsion: Pharmacokinetics, tissue distribution, antitumor efficacy, and toxicity. Journal of Agricultural and Food Chemistry 63 (28):6386–92. doi: 10.1021/acs.jafc.5b01883.
  • Zhou, Z., Y. Liu, Z. Liu, L. Fan, T. Dong, Y. Jin, M. D. A. Saldaña, and W. Sun. 2020. Sustained-release antibacterial pads based on nonwovens polyethylene terephthalate modified by β-cyclodextrin embedded with cinnamaldehyde for cold fresh pork preservation. Food Packaging and Shelf Life 26:100554. doi: 10.1016/j.fpsl.2020.100554.
  • Zhu, R., H. Liu, C. Liu, L. Wang, R. Ma, B. Chen, L. Li, J. Niu, M. Fu, D. Zhang, et al. 2017. Cinnamaldehyde in diabetes: A review of pharmacology, pharmacokinetics and safety. Pharmacological Research 122:78–89. doi: 10.1016/j.phrs.2017.05.019.

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