Recent advances in the concept of paraprobiotics: Nutraceutical/functional properties for promoting children health

References

• Achi, S. C., and P. M. Halami. 2019. In vitro comparative analysis of probiotic and functional attributes of indigenous isolates of Bifidobacteria. Current Microbiology 76 (3):304–11. doi: 10.1007/s00284-018-1615-9.
   PubMed Web of Science ®Google Scholar
• Almada, C. N., C. N. Almada-Érix, A. R. Roquetto, V. A. Santos-Junior, L. Cabral, M. F. Noronha, A. E. S. S. Gonçalves, P. D. Santos, A. D. Santos, J. Martinez, et al. 2021. Paraprobiotics obtained by six different inactivation processes: Impacts on the biochemical parameters and intestinal microbiota of Wistar male rats. International Journal of Food Sciences and Nutrition 72 (8):1057–1070. doi: 10.1080/09637486.2021.1906211.
   PubMed Web of Science ®Google Scholar
• Ananta, E., and D. Knorr. 2009. Comparison of inactivation pathways of thermal or high pressure inactivated Lactobacillus rhamnosus ATCC 53103 by flow cytometry analysis. Food Microbiology 26 (5):542–6. doi: 10.1016/j.fm.2009.01.008.
   PubMed Web of Science ®Google Scholar
• Ardita, C. S., J. W. Mercante, Y. M. Kwon, L. Luo, M. E. Crawford, D. N. Powell, R. M. Jones, and A. S. Neish. 2014. Epithelial adhesion mediated by pilin SpaC is required for Lactobacillus rhamnosus GG-induced cellular responses. Applied and Environmental Microbiology 80 (16):5068–77. doi: 10.1128/AEM.01039-14.
   PubMed Web of Science ®Google Scholar
• Asong, J., M. A. Wolfert, K. K. Maiti, D. Miller, and G. J. Boons. 2009. Binding and cellular activation studies reveal that toll-like receptor 2 can differentially recognize peptidoglycan from gram-positive and gram-negative bacteria. The Journal of Biological Chemistry 284 (13):8643–53. doi: 10.1074/jbc.M806633200.
   PubMed Web of Science ®Google Scholar
• Barros, C. P., L. Grom, J. T. Guimaraes, C. F. Balthazar, R. S. Rocha, R. Silva, C. N. Almada, T. C. Pimentel, E. L. Venâncio, I. C. Junior, et al. 2021. Paraprobiotic obtained by ohmic heating added in whey-grape juice drink is effective to control postprandial glycemia in healthy adults. Food Research International (Ottawa, ON) 140:109905. doi: 10.1016/j.foodres.2020.109905.
   PubMed Web of Science ®Google Scholar
• Barros, C. P., J. T. Guimarães, E. A. Esmerino, M. C. K. Duarte, M. C. Silva, R. Silva, B. M. Ferreira, A. S. Sant’Ana, M. Q. Freitas, and A. G. Cruz. 2020. Paraprobiotics and postbiotics: Concepts and potential applications in dairy products. Current Opinion in Food Science 32:1–8. doi: 10.1016/j.cofs.2019.12.003.
   Web of Science ®Google Scholar
• Barros, C. P., R. P. S. Pires, J. T. Guimarães, Y. K. D. Abud, C. N. Almada, T. C. Pimentel, C. S. Anna, L. D. B. De-Melo, M. C. K. H. Duarte, M. C. Silva, et al. 2021. Ohmic heating as a method of obtaining paraprobiotics: Impacts on cell structure and viability by flow cytometry. Food Research International 140:110061. doi: 10.1016/j.foodres.2020.110061.
   PubMed Web of Science ®Google Scholar
• Bitar, M. A., and R. Saade. 2013. The role of OM-85 BV (Broncho-Vaxom) in preventing recurrent acute tonsillitis in children. International Journal of Pediatric Otorhinolaryngology 77 (5):670–3. doi: 10.1016/j.ijporl.2013.01.009.
   PubMed Web of Science ®Google Scholar
• Black, R. E., L. H. Allen, Z. A. Bhutta, L. E. Caulfield, M. D. Onis, M. Ezzati, C. Mathers, and J. Rivera, and Maternal and Child Undernutrition Study Group. 2008. Maternal and child undernutrition: Global and regional exposures and health consequences. Lancet (London, England) 371 (9608):243–60. doi: 10.1016/S0140-6736(07)61690-0.
   PubMed Web of Science ®Google Scholar
• Bleau, C., A. Monges, K. Rashidan, J. P. Laverdure, M. Lacroix, M. R. V. Calsteren, M. Millette, R. Savard, and L. Lamontagne. 2010. Intermediate chains of exopolysaccharides from Lactobacillus rhamnosus RW-9595M increase IL-10 production by macrophages. Journal of Applied Microbiology 108 (2):666–75. doi: 10.1111/j.1365-2672.2009.04450.x.
   PubMed Web of Science ®Google Scholar
• Bodemer, C., G. Guillet, F. Cambazard, F. Boralevi, S. Ballarini, C. Milliet, P. Bertuccio, C. L. Vecchia, J. F. Bach, and Y. D. Prost. 2017. Adjuvant treatment with the bacterial lysate (OM-85) improves management of atopic dermatitis: A randomized study. PloS ONE 12 (3):e0161555. doi: 10.1371/journal.pone.0161555.
   PubMed Web of Science ®Google Scholar
• Boekhorst, J., M. Wels, M. Kleerebezem, and R. J. Siezen. 2006. The predicted secretome of Lactobacillus plantarum WCFS1 sheds light on interactions with its environment. Microbiology (Reading, England) 152 (Pt 11):3175–83. doi: 10.1099/mic.0.29217-0.
   PubMedGoogle Scholar
• Bron, P. A., S. Tomita, I. I. V. Swam, D. M. Remus, M. Meijerink, M. Wels, S. Okada, J. M. Wells, and M. Kleerebezem. 2012. Lactobacillus plantarum possesses the capability for wall teichoic acid backbone alditol switching. Microbial Cell Factories 11:123. doi: 10.1186/1475-2859-11-123.
   PubMed Web of Science ®Google Scholar
• Brothers, S., M. I. Asher, M. Jaksic, and A. W. Stewart. 2009. Effect of a Mycobacterium vaccae derivative on paediatric atopic dermatitis: A randomized, controlled trial. Clinical and Experimental Dermatology 34 (7):770–5. doi: 10.1111/j.1365-2230.2008.03153.x.
   PubMed Web of Science ®Google Scholar
• Camacho-Gonzalez, A., P. W. Spearman, and B. J. Stoll. 2013. Neonatal infectious diseases: Evaluation of neonatal sepsis. Pediatric Clinics of North America 60 (2):367–89. doi: 10.1016/j.pcl.2012.12.003.
   PubMed Web of Science ®Google Scholar
• Camp, H. J. O. D., A. Oosterhof, and J. H. Veerkamp. 1985. Interaction of bifidobacterial lipoteichoic acid with human intestinal epithelial cells. Infection and Immunity 47 (1):332–4. doi: 10.1128/iai.47.1.332-334.1985.
   PubMed Web of Science ®Google Scholar
• Campeotto, F., A. Suau, N. Kapel, F. Magne, V. Viallon, L. Ferraris, A. J. W. Dupriet, P. Soulaines, B. Leroux, N. Kalach, et al. 2011. A fermented formula in pre-term infants: Clinical tolerance, gut microbiota, down-regulation of faecal calprotectin and up-regulation of faecal secretory IgA. The British Journal of Nutrition 105 (12):1843–51. doi: 10.1017/S0007114510005702.
   PubMed Web of Science ®Google Scholar
• Canani, R. B., F. D. Filippis, R. Nocerino, M. Laiola, L. Paparo, A. Calignano, C. D. Caro, L. Coretti, L. Chiariotti, J. A. Gilbert, et al. 2017. Specific signatures of the gut microbiota and increased levels of butyrate in children treated with fermented cow’s milk containing heat-killed Lactobacillus paracasei CBA L74. Applied and Environmental Microbiology 83 (19):e01206–17. doi: 10.1128/AEM.01206-17.
   PubMed Web of Science ®Google Scholar
• Cassir, N., S. Benamar, and B. L. Scola. 2016. Clostridium butyricum: From beneficial to a new emerging pathogen. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 22 (1):37–45. doi: 10.1016/j.cmi.2015.10.014.
   PubMed Web of Science ®Google Scholar
• Choudhury, T. G., and D. Kamilya. 2019. Paraprobiotics: An aquaculture perspective. Reviews in Aquaculture 11 (4):1258–70. doi: 10.1111/raq.12290.
   Web of Science ®Google Scholar
• Corsello, G., M. Carta, R. Marinello, M. Picca, G. D. Marco, M. Micillo, D. Ferrara, P. Vigneri, G. Cecere, P. Ferri, et al. 2017. Preventive effect of cow’s milk fermented with Lactobacillus paracasei CBA L74 on common infectious diseases in children: A multicenter randomized controlled trial. Nutrients 9 (7):669. doi: 10.3390/nu9070669.
   PubMed Web of Science ®Google Scholar
• Dani, C., C. C. Coviello, I. I. Corsini, F. Arena, A. Antonelli, and G. M. Rossolini. 2016. Lactobacillus sepsis and probiotic therapy in newborns: Two new cases and literature review. AJP Reports 6 (1):e25–e29. doi: 10.1055/s-0035-1566312.
   PubMed Web of Science ®Google Scholar
• D’Auria, E., S. Panelli, L. Lunardon, M. Pajoro, L. Paradiso, S. Beretta, C. Loretelli, D. Tosi, M. Perini, G. Bedogni, et al. 2021. Rice flour fermented with Lactobacillus paracasei CBA L74 in the treatment of atopic dermatitis in infants: A randomized, double-blind, placebo-controlled trial. Pharmacological Research 163 (105284):105284.
   PubMedGoogle Scholar
• Deepak, V., S. Ramachandran, R. M. Balahmar, S. R. K. Pandian, S. D. Sivasubramaniam, H. Nellaiah, and K. Sundar. 2016. In vitro evaluation of anticancer properties of exopolysaccharides from Lactobacillus acidophilus in colon cancer cell lines. In Vitro Cellular & Developmental Biology. Animal 52 (2):163–73. doi: 10.1007/s11626-015-9970-3.
   PubMed Web of Science ®Google Scholar
• Deshpande, G., G. A. Jape, and S. Patole. 2018. Para-probiotics for preterm neonates- The next frontier. Nutrients 10 (7):871. doi: 10.3390/nu10070871.
   PubMed Web of Science ®Google Scholar
• Di, W., L. Zhang, H. Yi, X. Han, Y. Zhang, and L. Xin. 2018. Exopolysaccharides produced by Lactobacillus strains suppress HT-29 cell growth via induction of G0/G1 cell cycle arrest and apoptosis . Oncology Letters 16 (3):3577–86. doi: 10.3892/ol.2018.9129.
   PubMed Web of Science ®Google Scholar
• Doern, C. D., S. T. Nguyen, F. Afolabi, and C. A. D. Burnham. 2014. Probiotic-associated aspiration pneumonia due to Lactobacillus rhamnosus. Journal of Clinical Microbiology 52 (8):3124–6. doi: 10.1128/JCM.01065-14.
   PubMed Web of Science ®Google Scholar
• El-Deeb, N. M., A. M. Yassin, L. A. Al-Madboly, and A. El-Hawiet. 2018. A novel purified Lactobacillus acidophilus 20079 exopolysaccharide, LA-EPS-20079, molecularly regulates both apoptotic and NF-κB inflammatory pathways in human colon cancer . Microbial Cell Factories 17 (1):29. doi: 10.1186/s12934-018-0877-z.
   PubMedGoogle Scholar
• Ernstson, H., S. E. V. D. Leeuw, C. L. Redman, D. J. Meffert, G. Davis, C. Alfsen, and T. Elmqvist. 2010. Urban transitions: On urban resilience and human-dominated ecosystems. Ambio 39 (8):531–45. doi: 10.1007/s13280-010-0081-9.
   PubMed Web of Science ®Google Scholar
• Esposito, S., S. Bianchini, S. Bosis, C. Tagliabue, I. Coro, A. Argentiero, and N. Principi. 2019a. A randomized, placebo-controlled, double-blinded, single-centre, phase IV trial to assess the efficacy and safety of OM-85 in children suffering from recurrent respiratory tract infections. Journal of Translational Medicine 17 (1):284.
   PubMed Web of Science ®Google Scholar
• Esposito, S., S. Bianchini, I. Polinori, and N. Principi. 2019b. Impact of OM-85 given during two consecutive years to children with a history of recurrent respiratory tract infections: A retrospective study. International Journal of Environmental Research and Public Health 16 (6):1065. doi: 10.3390/ijerph16061065.
   PubMed Web of Science ®Google Scholar
• Esposito, S., P. Marchisio, E. Prada, C. Daleno, L. Porretti, R. Carsetti, A. Bosco, V. Ierardi, A. Scala, and N. Principi. 2014. Impact of a mixed bacterial lysate (OM-85 BV) on the immunogenicity, safety and tolerability of inactivated influenza vaccine in children with recurrent respiratory tract infection. Vaccine 32 (22):2546–52. doi: 10.1016/j.vaccine.2014.03.055.
   PubMed Web of Science ®Google Scholar
• FAO/WHO. 2001. Health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. Report of a Joint FAO/WHO expert consultation on evaluation of health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria. Accessed February 2, 2021. untitled (fao.org).
   Google Scholar
• FAO/WHO. 2002. Guidelines for the evaluation of probiotics in food, Food and Agriculture Organization of the United Nations and World Health Organization group report. Joint FAO/WHO Working Group Report on Drafting Guidelines for the Evaluation of Probiotics in Food: London, Ontario. Accessed February 11, 2021. https://www.who.int/foodsafety/fs_management/en/probiotic_guidelines.pdf.
   Google Scholar
• Gensollen, T., and R. S. Blumberg. 2017. Correlation between early-life regulation of the immune system by microbiota and allergy development. The Journal of Allergy and Clinical Immunology 139 (4):1084–91. doi: 10.1016/j.jaci.2017.02.011.
   PubMed Web of Science ®Google Scholar
• Gómez, N., D. García, I. Álvarez, J. Raso, and S. Condón. 2005. A model describing the kinetics of inactivation of Lactobacillus plantarum in a buffer system of different pH and in orange and apple juice. Journal of Food Engineering 70 (1):7–14. doi: 10.1016/j.jfoodeng.2004.09.007.
   Web of Science ®Google Scholar
• Guenther, K., E. Straube, W. Pfister, A. Guenther, and A. Huebler. 2010. Sever sepsis after probiotic treatment with Escherichia coli NISSLE 1917. The Pediatric Infectious Disease Journal 29 (2):188–9. doi: 10.1097/INF.0b013e3181c36eb9.
   PubMed Web of Science ®Google Scholar
• Guo, B., N. Xie, and Y. Wang. 2015. Cooperative effect of Bifidobacteria lipoteichoic acid combined with 5-fluorouracil on hepatoma-22 cells growth and apoptosis. Bulletin du Cancer 102 (3):204–12. doi: 10.1016/j.bulcan.2014.09.003.
   PubMed Web of Science ®Google Scholar
• Haines, J., E. Haycraft, L. Lytle, S. Nicklaus, F. J. Kok, M. Merdji, M. Fisberg, L. A. Moreno, O. Goulet, and S. O. Hughes. 2019. Nurturing children’s healthy eating: Position statement. Appetite 137:124–33. doi: 10.1016/j.appet.2019.02.007.
   PubMed Web of Science ®Google Scholar
• Han, R. F., H. Y. Li, J. W. Wang, and X. J. Cong. 2016. Study on clinical effect and immunologic mechanism of infants capillary bronchitis secondary bronchial asthma treated with bacterial lysates Broncho-Vaxom. European Review for Medical and Pharmacological Sciences 20 (10):2151–5.
   PubMed Web of Science ®Google Scholar
• Hishiki, H., T. Kawashima, N. M. Tsuji, N. Ikari, R. Takemura, H. Kido, and N. Shimojo. 2020. A double-blind, randomized, placebo-controlled trial of heat-killed Pediococcus acidilactici K15 for prevention of respiratory tract infections among preschool children. Nutrients 12 (7):1989. doi: 10.3390/nu12071989.
   PubMed Web of Science ®Google Scholar
• Hotoura, E., V. Giapros, A. Kostoula, P. Spyrou, and S. Andronikou. 2012. Pre-inflammatory mediators and lymphocyte subpopulations in preterm neonates with sepsis. Inflammation 35 (3):1094–101. doi: 10.1007/s10753-011-9416-3.
   PubMed Web of Science ®Google Scholar
• Hurmalainen, V., S. Edelman, J. Antikainen, M. Baumann, K. Lähteenmäki, and T. K. Korhonen. 2007. Extracellular proteins of Lactobacillus crispatus enhance activation of human plasminogen. Microbiology (Reading, England) 153 (Pt 4):1112–22. doi: 10.1099/mic.0.2006/000901-0.
   PubMedGoogle Scholar
• Husni, R. N., S. M. Gordon, J. A. Washington, and D. L. Longworth. 1997. Lactobacillus bacteremia and endocarditis: Review of 45 cases. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 25 (5):1048–55. doi: 10.1086/516109.
   PubMed Web of Science ®Google Scholar
• Ivanov, D., C. Emonet, F. Foata, M. Affolter, M. Delley, M. Fisseha, S. Blum-Sperisen, S. Kochhar, and F. Arigoni. 2006. A serpin from the gut bacterium Bifidobacterium longum inhibits eukaryotic elastase-like serine proteases. The Journal of Biological Chemistry 281 (25):17246–52. doi: 10.1074/jbc.M601678200.
   PubMed Web of Science ®Google Scholar
• Jensen, H., S. Roos, H. Jonsson, I. Rud, S. Grimmer, J. P. V. Pijkeren, R. A. Britton, and L. Axelsson. 2014. Role of Lactobacillus reuteri cell and mucus-binding protein A (CmbA) in adhesion to intestinal epithelial cells and mucus in vitro. Microbiology (Reading, England) 160 (Pt 4):671–81. doi: 10.1099/mic.0.073551-0.
   PubMedGoogle Scholar
• Jeong, K., M. Kim, S. H. Jeon, Y. H. Kim, and S. Lee. 2020. A randomized trial of Lactobacillus rhamnosus IDCC 3201 tyndallizate (RHT3201) for treating atopic dermatitis. Pediatric Allergy and Immunology: Official Publication of the European Society of Pediatric Allergy and Immunology 31 (7):783–92. doi: 10.1111/pai.13269.
   PubMed Web of Science ®Google Scholar
• Kamiya, T., L. Wang, P. Forsythe, G. Goettsche, Y. Mao, Y. Wang, G. Tougas, and J. Bienenstock. 2006. Inhibitory effects of Lactobacillus reuteri on visceral pain induced by colorectal distension in Sprague-Dawley rats. Gut 55 (2):191–6.
   PubMed Web of Science ®Google Scholar
• Kankainen, M., L. Paulin, S. Tynkkynen, I. von Ossowski, J. Reunanen, P. Partanen, R. Satokari, S. Vesterlund, A. P. A. Hendrickx, S. Lebeer, et al. 2009. Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein . Proceedings of the National Academy of Sciences of the United States of America 106 (40):17193–8. doi: 10.1073/pnas.0908876106.
   PubMed Web of Science ®Google Scholar
• Karaca, N. E., N. Gulez, G. Aksu, E. Azarsiz, and N. Kutukculer. 2011. Does OM-85 BV prophylaxis trigger autoimmunity in IgA deficient children? International Immunopharmacology 11 (11):1747–51. doi: 10.1016/j.intimp.2011.06.009.
   PubMed Web of Science ®Google Scholar
• Kiencke, P., K. Viehmann, and R. Rychlik. 2013. Cost-effectiveness analysis, prevention of atopic dermatitis by oral application of bacterial lysate in newborns/small children. The European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care 14 (6):995–1002. doi: 10.1007/s10198-012-0448-x.
   PubMed Web of Science ®Google Scholar
• Kim, K. W., S. S. Kang, S. J. Woo, O. J. Park, K. B. Ahn, K. D. Song, H. K. Lee, C. H. Yun, and S. H. Han. 2017. Lipoteichoic acid of probiotic Lactobacillus plantarum attenuates poly I:C-Induced IL-8 production in porcine intestinal epithelial cells. Frontiers in Microbiology 8:1827. doi: 10.3389/fmicb.2017.01827.
   PubMed Web of Science ®Google Scholar
• Kim, J. Y., H. J. Woo, Y. S. Kim, and H. J. Lee. 2002. Screening for antiproliferative effects of cellular components from lactic acid bacteria against human cancer cell lines. Biotechnology Letters 24 (17):1431–6. doi: 10.1023/A:1019875204323.
   Web of Science ®Google Scholar
• Kleerebezem, M., P. Hols, E. Bernard, T. Rolain, M. Zhou, R. J. Siezen, and P. A. Bron. 2010. The extracellular biology of the Lactobacilli. FEMS Microbiology Reviews 34 (2):199–230. doi: 10.1111/j.1574-6976.2009.00208.x.
   PubMed Web of Science ®Google Scholar
• Kolling, Y., S. Salva, J. Villena, and S. Alvarez. 2018. Are the immunomodulatory properties of Lactobacillus rhamnosus CRL1505 peptidoglycan common for all Lactobacilli during respiratory infection in malnourished mice? PLoS ONE 13 (3):e0194034. doi: 10.1371/journal.pone.0194034.
   PubMed Web of Science ®Google Scholar
• Kopp, M. V., I. Hennemuth, A. Heinzmann, and R. Urbanek. 2008. Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: No clinical effects of Lactobacillus GG supplementation. Pediatrics 121 (4):e850–e856.
   PubMed Web of Science ®Google Scholar
• Kothari, D., S. Patel, and S. K. Kim. 2019. Probiotic supplements might not be universally-effective and safe: A review. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie 111:537–47. doi: 10.1016/j.biopha.2018.12.104.
   PubMed Web of Science ®Google Scholar
• Kšonžeková, P., P. Bystrický, S. Vlčková, V. Pätoprstý, L. Pulzová, D. Mudroňová, T. Kubašková, T. Csank, and Ľ. Tkáčiková. 2016. Exopolysaccharides of Lactobacillus reuteri: Their influence on adherence of E. coli to epithelial cells and inflammatory response. Carbohydrate Polymers 141:10–9. doi: 10.1016/j.carbpol.2015.12.037.
   PubMed Web of Science ®Google Scholar
• Kunz, A. N., J. M. Noel, and M. P. Fairchok. 2004. Two Cases of Lactobacillus bacteremia during probiotic treatment of short gut syndrome. Journal of Pediatric Gastroenterology and Nutrition 38 (4):457–8.
   PubMed Web of Science ®Google Scholar
• Land, M. H., K. Rouster-Stevens, C. R. Woods, M. L. Cannon, J. Cnota, and A. K. Shetty. 2005. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 115 (1):178–81. doi: 10.1542/peds.2004-2137.
   PubMed Web of Science ®Google Scholar
• Lau, S., K. Gerhold, K. Zimmermann, C. W. Ockeloen, S. Rossberg, P. Wagner, C. Sulser, R. Bunikowski, I. Witt, J. Wauer, et al. 2012. Oral application of bacterial lysate in infancy decreases the risk of atopic dermatitis in children with 1 atopic parent in a randomized, placebo-controlled trial. The Journal of Allergy and Clinical Immunology 129 (4):1040–7. doi: 10.1016/j.jaci.2012.02.005.
   PubMed Web of Science ®Google Scholar
• Lebeer, S., P. A. Bron, M. L. Marco, J. P. V. Pijkeren, M. O. Motherway, C. Hill, B. Pot, S. Roos, and T. Klaenhammer. 2018. Identification of probiotic effector molecules: Present state and future perspectives. Current Opinion in Biotechnology 49:217–23. doi: 10.1016/j.copbio.2017.10.007.
   PubMed Web of Science ®Google Scholar
• Lebeer, S., J. Vanderleyden, and S. C. J. D. Keersmaecker. 2010. Host interactions of probiotic bacterial surface molecules: Comparison with commensals and pathogens. Nature Reviews. Microbiology 8 (3):171–84. doi: 10.1038/nrmicro2297.
   PubMed Web of Science ®Google Scholar
• Liong, M. T. 2008. Safety of probiotics: Translocation and infection. Nutrition Reviews 66 (4):192–202. doi: 10.1111/j.1753-4887.2008.00024.x.
   PubMed Web of Science ®Google Scholar
• Li-Sheng, W., P. Ling-Jia, S. Li, S. Yong, Z. Ya-Li, and Z. Dian-Yuan. 1999. The apoptosis of experimental colorectal carcinoma cells induced by peptidoglycan of Bifidobacterium and the expresion of apoptotic regulating genes. Chinese Journal of Cancer Research 11 (3):184–7. doi: 10.1007/s11670-999-0008-9.
   Google Scholar
• Liu, Q., Z. Yu, F. Tian, J. Zhao, H. Zhang, Q. Zhai, and W. Chen. 2020. Surface components and metabolites of probiotics for regulation of intestinal epithelial barrier. Microbial Cell Factories 19 (1):23. doi: 10.1186/s12934-020-1289-4.
   PubMed Web of Science ®Google Scholar
• Lopez, M., N. Li, J. Kataria, M. Russell, and J. Neu. 2008. Live and ultraviolet-inactivated Lactobacillus rhamnosus GG decrease flagellin-induced interleukin-8 production in Caco-2 Cells. 2008. The Journal of Nutrition 138 (11):2264–8. doi: 10.3945/jn.108.093658.
   PubMed Web of Science ®Google Scholar
• López, P., D. C. Monteserín, D. C M. Gueimonde, C. G. D L. Reyes-Gavilán, A. Margolles, A. Suárez, and P. Ruas-Madiedo. 2012. Exopolysaccharide-producing Bifidobacterium strains elicit different in vitro responses upon interaction with human cells. Food Research International 46 (1):99–107. doi: 10.1016/j.foodres.2011.11.020.
   Web of Science ®Google Scholar
• Lu, Y., Y. Li, L. Xu, M. Xia, and L. Cao. 2015. Bacterial lysate increases the percentage of natural killer T cells in peripheral blood and alleviates asthma in children. Pharmacology 95 (3–4):139–44. doi: 10.1159/000377683.
   PubMed Web of Science ®Google Scholar
• Malamud, M., P. Carasi, T. Freire, and M. D. L. A. Serradell. 2018. S-layer glycoprotein from Lactobacillus kefiri CIDCA 8348 enhances macrophages response to LPS in a Ca+2-dependent manner. Biochemical and Biophysical Research Communications 495 (1):1227–32. doi: 10.1016/j.bbrc.2017.11.127.
   PubMed Web of Science ®Google Scholar
• Maldonado, J., F. Cañabate, L. Sempere, F. Vela, A. R. Sánchez, E. Narbona, E. López-Huertas, A. Geerlings, A. D. Valero, M. Olivares, et al. 2012. Human milk probiotic Lactobacillus fermentum CECT5716 reduces the incidence of gastrointestinal and upper respiratory tract infections in infants. Journal of Pediatric Gastroenterology and Nutrition 54 (1):55–61. doi: 10.1097/MPG.0b013e3182333f18.
   PubMed Web of Science ®Google Scholar
• Malone, S. K. 2005. Improving the quality of students’ dietary intake in the school setting. The Journal of School Nursing : The Official Publication of the National Association of School Nurses 21 (2):70–6. doi: 10.1177/10598405050210020301.
   PubMedGoogle Scholar
• Mater, D. D. G., P. Langella, G. Corthier, and M. J. Flores. 2008. A probiotic Lactobacillus strain can acquire vancomycin resistance during digestive transit in mice. Journal of Molecular Microbiology and Biotechnology 14 (1–3):123–7. doi: 10.1159/000106091.
   PubMed Web of Science ®Google Scholar
• Mattarelli, P., and B. Biavati. 2018. Species in the genus Bifidobacterium. In The Bifidobacteria and related organisms, ed. P. Mattarelli, B. Biavati, W. H. Holzapfel, and B. J. B. Wood, 9–48. London, United Kingdom: Elsevier.
   Google Scholar
• McCarville, J. L., J. Dong, A. Caminero, M. Bermudez-Brito, J. Jury, J. A. Murray, S. Duboux, M. Steinmann, M. Delley, M. Tangyu, et al. 2017. A commensal Bifidobacterium longum strain prevents gluten-related immunopathology in mice through expression of a serine protease inhibitor. Applied and Environmental Microbiology 83 (19):e01323–e01317. doi: 10.1128/AEM.01323-17.
   PubMed Web of Science ®Google Scholar
• Meng, J., X. Zhu, S. M. Gao, Q. X. Zhang, Z. Sun, and R. R. Lu. 2014. Characterization of surface layer proteins and its role in probiotic properties of three Lactobacillus strains. International Journal of Biological Macromolecules 65:110–4. doi: 10.1016/j.ijbiomac.2014.01.024.
   PubMed Web of Science ®Google Scholar
• Mo, S., B. S. Kim, S. J. Yun, J. J. Lee, S. H. Yoon, and C. H. Oh. 2015. Genome sequencing of Clostridium butyricum DKU-01, isolated from infant feces. Gut Pathogens 7 (8):8.
   PubMedGoogle Scholar
• Mohamadzadeh, M., E. A. Pfeiler, J. B. Brown, M. Zadeh, M. Gramarossa, E. Managlia, P. Bere, B. Sarraj, M. W. Khan, K. C. Pakanati, et al. 2011. Regulation of induced colonic inflammation by Lactobacillus acidophilus deficient in lipoteichoic acid. Proceedings of the National Academy of Sciences of Sciences 108 (Supplement_1):4623–30. doi: 10.1073/pnas.1005066107.
   PubMedGoogle Scholar
• Morisset, M., C. Aubert-Jacquin, P. Soulaines, D. A. Moneret-Vautrin, and C. Dupont. 2011. A non-hydrolyzed, fermented milk formula reduces digestive and respiratory events in infants at high risk of allergy. European Journal of Clinical Nutrition 65 (2):175–83. doi: 10.1038/ejcn.2010.250.
   PubMed Web of Science ®Google Scholar
• Nagaoka, M., S. Hashimoto, T. Watanabe, T. Yokokura, and Y. Mori. 1994. Anti-ulcer effects of lactic acid bacteria and their cell wall polysaccharides. Biological & Pharmaceutical Bulletin 17 (8):1012–7. doi: 10.1248/bpb.17.1012.
   PubMed Web of Science ®Google Scholar
• Nakamura, F., Y. Ishida, D. Sawada, N. Ashida, T. Sugawara, M. Sakai, T. Goto, T. Kawada, and S. Fujiwara. 2016. Fragmented lactic acid bacterial cells activate peroxisome proliferator-activated receptors and ameliorate dyslipidemia in obese mice. Journal of Agricultural Food Chemistry 64 (12):1249–59.
   Web of Science ®Google Scholar
• Nakata, J., T. Hirota, H. Umemura, T. Nakagawa, N. Kando, M. Futamura, Y. Nakamura, and K. Ito. 2019. Additive effect of Lactobacillus acidophilus L-92 on children with atopic dermatitis concomitant with food allergy. Asia Pacific Allergy 9 (2):e18. doi: 10.5415/apallergy.2019.9.e18.
   PubMed Web of Science ®Google Scholar
• Nataraj, B. H., S. A. Ali, P. V. Behare, and H. Yadav. 2020. Postbiotics-parabiotics: The new horizons in microbial biotherapy and functional foods. Microbial Cell Factories 19 (1):168. doi: 10.1186/s12934-020-01426-w.
   PubMed Web of Science ®Google Scholar
• Nicklas, T., and R. Johnson, American Dietetic Association. 2004. Position of the American dietetic- association: Dietary guidance for healthy children ages 2 to 11 years. Journal of the American Dietetic Association 104 (4):660–77.
   PubMedGoogle Scholar
• Nikolic, M., P. López, I. Strahinic, A. Suárez, M. Kojic, M. Fernández-García, L. Topisirovic, N. Golic, and P. Ruas-Madiedo. 2012. Characterisation of the exopolysaccharide (EPS)-producing Lactobacillus paraplantarum BGCG11 and its non-EPS producing derivative strains as potential probiotics. International Journal of Food Microbiology 158 (2):155–62. doi: 10.1016/j.ijfoodmicro.2012.07.015.
   PubMed Web of Science ®Google Scholar
• Nocerino, R., L. Paparo, G. Terrin, V. Pezzella, A. Amoroso, L. Cosenza, G. Cecere, G. De Marco, M. Micillo, F. Albano, et al. 2017. Cow’s milk and rice fermented with Lactobacillus paracasei CBA L74 prevent infectious diseases in children: A randomized controlled trial. Clinical Nutrition (Edinburgh, Scotland) 36 (1):118–25. doi: 10.1016/j.clnu.2015.12.004.
   PubMed Web of Science ®Google Scholar
• Noh, S. Y., S. S. Kang, C. H. Yun, and S. H. Han. 2015. Lipoteichoic acid from Lactobacillus plantarum inhibits Pam2CSK4-induced IL-8 production in human intestinal epithelial cells. Molecular Immunology 64 (1):183–9. doi: 10.1016/j.molimm.2014.11.014.
   PubMed Web of Science ®Google Scholar
• Onubi, O. J., A. S. Poobalan, B. Dineen, D. Marais, and G. McNeill. 2015. Effects of probiotics on child growth: A systematic review. Journal of Health. Population and Nutrition 34 (8):1–15.
   PubMedGoogle Scholar
• Perdana, J., L. Bereschenko, M. B. Fox, J. H. Kuperus, M. Kleerebezem, R. M. Boom, and M. A. I. Schutyser. 2013. Dehydration and thermal inactivation of Lactobacillus plantarum WCFS1: Comparing single droplet drying to spray and freeze drying. Food Research International 54 (2):1351–9. doi: 10.1016/j.foodres.2013.09.043.
   Web of Science ®Google Scholar
• Rampengan, N. H., J. Manoppo, and S. M. Warouw. 2010. Comparison of efficacies between live and killed probiotics in children with lactose malabsorption. Southeast Asian Journal of Tropical Medicine and Public Health 41 (2):474–81.
   PubMed Web of Science ®Google Scholar
• Rather, I. A., B.-C. Kim, L.-C. Lew, S.-K. Cha, J. H. Lee, G.-J. Nam, R. Majumder, J. Lim, S.-K. Lim, Y.-J. Seo, et al. 2021. Oral administration of live and dead cells of Lactobacillus sakei proBio65 alleviated atopic dermatitis in children and adolescents: A randomized, double-blind, and placebo-controlled study. Probiotics and Antimicrobial Proteins 13 (2):315–26. doi: 10.1007/s12602-020-09654-7.
   PubMed Web of Science ®Google Scholar
• Raz, E., and D. Rachmilewitz. 2005. Inactivated probiotic bacteria and methods of use thereof. Patent n.US20050180962 A1, 18 ago.
   Google Scholar
• Razi, C. H., K. Harmancı, A. Abacı, O. Özdemir, O. S. Hızlı, R. Renda, and F. Keskin. 2010. The immunostimulant OM-85 BV prevents wheezing attacks in preschool children. Journal of Allergy and Clinical Immunology 126 (4):763–9. doi: 10.1016/j.jaci.2010.07.038.
   PubMed Web of Science ®Google Scholar
• Reunanen, J., I. V. Ossowski, A. P. A. Hendrickx, A. Palva, and W. M. D. Vos. 2012. Characterization of the SpaCBA pilus fibers in the probiotic Lactobacillus rhamnosus GG. Applied and Environmental Microbiology 78 (7):2337–44. doi: 10.1128/AEM.07047-11.
   PubMed Web of Science ®Google Scholar
• Rocha-Ramírez, L. M., B. Hernández-Ochoa, S. Gómez-Manzo, J. Marcial-Quino, N. Cárdenas-Rodríguez, S. Centeno-Leija, and M. García-Garibay. 2020. Impact of heat-killed Lactobacillus casei strain IMAU60214 on the immune function of macrophages in malnourished children. Nutrients 12 (8):2303. doi: 10.3390/nu12082303.
   PubMed Web of Science ®Google Scholar
• Rosander, A., E. Connolly, and S. Roos. 2008. Removal of antibiotic resistance gene-carrying plasmids from Lactobacillus reuteri ATCC 55730 and characterization of the resulting daughter strain, L. reuteri DSM 17938. Applied and Environmental Microbiology 74 (19):6032–40. doi: 10.1128/AEM.00991-08.
   PubMed Web of Science ®Google Scholar
• Rozy, A., and J. Chorostowska-Wynimko. 2008. Bacterial immunostimulants-mechanism of action and clinical application in respiratory diseases. Advances in Respiratory Medicine 76 (5):353–9.
   Google Scholar
• Ruas-Madiedo, P., and C. G. D. L. Reyes-Gavilán. 2005. Methods for the screening, isolation, and characterization of exopolysaccharides produced by lactic acid bacteria. Journal of Dairy Science 88 (3):843–56. doi: 10.3168/jds.S0022-0302(05)72750-8.
   PubMed Web of Science ®Google Scholar
• Rusu, E., G. Enache, R. Cursaru, A. Alexescu, R. Radu, O. Onila, T. Cavallioti, F. Rusu, M. Posea, M. Jinga, et al. 2019. Prebiotics and probiotics in atopic dermatitis. Experimental and Therapeutic Medicine 18 (2):926–31. doi: 10.3892/etm.2019.7678.
   PubMed Web of Science ®Google Scholar
• Salazar, N., A. Prieto, J. A. Leal, B. Mayo, J. C. Bada-Gancedo, C. G. D. L. Reyes-Gavilán, and P. Ruas-Madiedo. 2009. Production of exopolysaccharides by Lactobacillus and Bifidobacterium strains of human origin, and metabolic activity of the producing bacteria in milk. Journal of Dairy Science 92 (9):4158–68. doi: 10.3168/jds.2009-2126.
   PubMed Web of Science ®Google Scholar
• Santibañez, A., D. Paine, M. Parra, C. Muñoz, N. Valdes, C. Zapata, R. Vargas, A. Gonzalez, and M. Tello. 2021. Oral administration of Lactococcus lactis producing interferon type ii, enhances the immune response against bacterial pathogens in rainbow trout. Frontiers in Immunology 12 (696803):696803.
   PubMedGoogle Scholar
• Sawada, D., Y. Kuwano, H. Tanaka, S. Hara, Y. Uchiyama, T. Sugawara, S. Fujiwara, K. Rokutan, and K. Nishida. 2019. Daily intake of Lactobacillus gasseri CP2305 relieves fatigue and stress-related symptoms in male university Ekiden runners: A double-blind, randomized, and placebo-controlled clinical trial. Journal of Functional Foods 57:465–76. doi: 10.1016/j.jff.2019.04.022.
   Web of Science ®Google Scholar
• Schaad, U. B. 2010. OM-85 BV, an immunostimulant in pediatric recurrent respiratory tract infections: A systematic review. World Journal of Pediatrics 6 (1):5–12. doi: 10.1007/s12519-010-0001-x.
   PubMed Web of Science ®Google Scholar
• Schaad, U. B., R. Mütterlein, H. Goffin, and B.-C S. Group. 2002. Immunostimulation with OM-85 in children with recurrent infections of the upper respiratory tract: A double-blind, placebo-controlled multicenter study. Chest 122 (6):2042–9. doi: 10.1378/chest.122.6.2042.
   PubMed Web of Science ®Google Scholar
• Schleifer, K. H., and O. Kandler. 1973. Peptidoglycan types of bacterial cell walls and their taxonomic implications. Bacteriological Reviews 37 (2):258.
   PubMedGoogle Scholar
• Schmitt, J., K. Schwarz, H. Baurecht, M. Hotze, R. Fölster-Holst, E. Rodríguez, Y. A. E. Lee, A. Franke, F. Degenhardt, W. Lieb, et al. 2016. Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes. The Journal of Allergy and Clinical Immunology 137 (1):130–6. doi: 10.1016/j.jaci.2015.06.029.
   PubMed Web of Science ®Google Scholar
• Schumann, P. 2011. Peptidoglycan structure. Methods in Microbiology 38:101–29.
   Web of Science ®Google Scholar
• Sekine, K., J. Ohta, M. Onishi, T. Tatsuki, Y. Shimokawa, T. Toida, T. Kawashima, and Y. Hashimoto. 1995. Analysis of antitumor properties of effector cells stimulated with a cell wall preparation (wpg) of Bifidobacterium infantis. Biological & Pharmaceutical Bulletin 18 (1):148–53. doi: 10.1248/bpb.18.148.
   PubMed Web of Science ®Google Scholar
• Sekine, K., T. Toida, M. Saito, M. Kuboyama, T. Kawashima, and Y. Hashimoto. 1985. A new morphologically characterized cell wall preparation (whole peptidoglycan) from Bifidobacterium infantis with a higher efficacy on the regression of an established tumor in mice. Cancer Research 45 (3):1300–7.
   PubMed Web of Science ®Google Scholar
• Sengupta, R., E. Altermann, R. C. Anderson, W. C. Mcnabb, P. J. Moughan, and N. C. Roy. 2013. The role of cell surface architecture of Lactobacilli in host-microbe interactions in the gastrointestinal tract. Mediators of Inflammation 2013:237921. doi: 10.1155/2013/237921.
   PubMed Web of Science ®Google Scholar
• Shida, K., J. R. Kiyoshima-Shibata, M. Kaji, M. Nagaoka, and M. Nanno. 2009. Peptidoglycan from Lactobacilli inhibits interleukin-12 production by macrophages induced by Lactobacillus casei through toll-like receptor 2-dependent and independent mechanisms. Immunology 128 (1 Suppl):e858–e69.
   PubMed Web of Science ®Google Scholar
• Shin, H. S., S. Y. Park, D. K. Lee, S. A. Kim, H. M. An, J. R. Kim, M. J. Kim, M. G. Cha, S. W. Lee, K. J. Kim, et al. 2010. Hypocholesterolemic effect of sonication-killed Bifidobacterium longum isolated from healthy adult Koreans in high cholesterol fed rats. Archives of Pharmacal Research 33 (9):1425–31. doi: 10.1007/s12272-010-0917-7.
   PubMed Web of Science ®Google Scholar
• Siciliano, R. A., A. Reale, M. F. Mazzeo, S. Morandi, T. Silvetti, and M. Brasca. 2021. Paraprobiotics: A new perspective for functional foods and nutraceuticals. Nutrients 13 (4):1225. doi: 10.3390/nu13041225.
   PubMed Web of Science ®Google Scholar
• Smelt, M. J., B. J. D. Haan, P. A. Bron, I. V. Swam, M. Meijerink, J. M. Wells, M. Kleerebezem, M. M. Faas, and P. D. Vos. 2013. The impact of Lactobacillus plantarumWCFS1 teichoic acid D-alanylation on the generation of effector and regulatory T-cells in healthy mice. PLoS One. 8 (4):e0063099. doi: 10.1371/journal.pone.0063099.
   Web of Science ®Google Scholar
• Spurbeck, R. R., and C. G. Arvidson. 2010. Lactobacillus jensenii surface-associated proteins inhibit Neisseria gonorrhoeae adherence to epithelial cells. Infection and Immunity 78 (7):3103–11. doi: 10.1128/IAI.01200-09.
   PubMed Web of Science ®Google Scholar
• Steurer-Stey, C., L. Lagler, D. A. Straub, J. Steurer, and L. M. Bachmann. 2007. Oral purified bacterial extracts in acute respiratory tract infections in childhood: A systematic quantitative review. European Journal of Pediatrics 166 (4):365–76. doi: 10.1007/s00431-006-0248-3.
   PubMed Web of Science ®Google Scholar
• Sugawara, T., D. Sawada, Y. Ishida, K. Aihara, Y. Aoki, I. Takehara, K. Takano, and S. Fujiwara. 2016. Regulatory effect of paraprobiotic Lactobacillus gasseri CP2305 on gut environment and function. Microbial Ecology in Health and Disease 27 (30259).
   Google Scholar
• Tanaka, K., T. Tsukahara, T. Yanagi, S. Nakahara, O. Furukawa, H. Tsutsui, and S. Koshida. 2017. Bifidobacterium bifidum OLB6378 simultaneously enhances systemic and mucosal humoral immunity in low birth weight infants: A non-randomized study. Nutrients 9 (3):195. doi: 10.3390/nu9030195.
   PubMed Web of Science ®Google Scholar
• Tanzer, J. M., A. Thompson, C. Lang, B. Cooper, L. Hareng, A. Gamer, A. Reindl, and M. Pompejus. 2010. Caries inhibition by and safety of Lactobacillus paracasei DSMZ16671. Journal of Dental Research 89 (9):921–6. doi: 10.1177/0022034510369460.
   PubMed Web of Science ®Google Scholar
• Taverniti, V., and S. Guglielmetti. 2011. The immunomodulatory properties of probiotic microorganisms beyond their viability (ghost probiotics: Proposal of paraprobiotic concept). Genes & Nutrition 6 (3):261–74. doi: 10.1007/s12263-011-0218-x.
   PubMed Web of Science ®Google Scholar
• Taylor, A. L., J. A. Dunstan, and S. L. Prescott. 2007. Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: A randomized controlled trial. The Journal of Allergy and Clinical Immunology 119 (1):184–91. doi: 10.1016/j.jaci.2006.08.036.
   PubMed Web of Science ®Google Scholar
• Troge, A., W. Scheppach, B. O. Schroeder, S. A. Rund, K. Heuner, J. Wehkamp, E. F. Stange, and T. A. Oelschlaeger. 2012. More than a marine propeller-the flagellum of the probiotic Escherichia coli strain Nissle 1917 is the major adhesin mediating binding to human mucus. International Journal of Medical Microbiology: IJMM 302 (7–8):304–14. doi: 10.1016/j.ijmm.2012.09.004.
   PubMed Web of Science ®Google Scholar
• Tytgat, H. L. P., N. H. van Teijlingen, R. M. A. Sullan, F. P. Douillard, P. Rasinkangas, M. Messing, J. Reunanen, R. Satokari, J. Vanderleyden, Y. F. Dufrêne, et al. 2016. Probiotic gut microbiota isolate interacts with dendritic cells via glycosylated heterotrimeric pili. PLoS ONE 11 (3):e0151824. doi: 10.1371/journal.pone.0151824.
   PubMed Web of Science ®Google Scholar
• UNICEF. 2019. The State of the world’s children 2019: Children, food and nutrition. Accessed March 16, 2021. The State of the World’s Children 2019: Children, food and nutrition - World | ReliefWeb. https://reliefweb.int/report/world/state-worlds-children-2019-children-food-and-nutrition
   Google Scholar
• Vahabnezhad, E., A. B. Mochon, L. J. Wozniak, and D. A. Ziring. 2013. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. Journal of Clinical Gastroenterology 47 (5):437–9. doi: 10.1097/MCG.0b013e318279abf0.
   PubMed Web of Science ®Google Scholar
• Vandenplas, Y., A. Bacarea, M. Marusteri, V. Bacarea, M. Constantin, and M. Manolache. 2017. Efficacy and safety of APT198K for the treatment of infantile colic: A pilot study. Journal of Comparative Effectiveness Research 6 (2):137–44. doi: 10.2217/cer-2016-0059.
   PubMed Web of Science ®Google Scholar
• Veerkamp, J. H. 1971. The structure of the cell wall peptidoglycan of Bifidobacterium bifidum var. pennsylvanicus. Archives of Biochemistry and Biophysics 143 (1):204–11. doi: 10.1016/0003-9861(71)90200-1.
   PubMed Web of Science ®Google Scholar
• Wang, J., X. Zhao, Y. Yang, A. Zhao, and Z. Yang. 2015. Characterization and bioactivities of an exopolysaccharide produced by Lactobacillus plantarum YW32. International Journal of Biological Macromolecules 74:119–26. doi: 10.1016/j.ijbiomac.2014.12.006.
   PubMed Web of Science ®Google Scholar
• Weidenmaier, C., and A. Peschel. 2008. Teichoic acids and related cell-wall glycopolymers in gram-positive physiology and host interactions. Nature Reviews. Microbiology 6 (4):276–87. doi: 10.1038/nrmicro1861.
   PubMed Web of Science ®Google Scholar
• Wu, M. H., T. M. Pan, Y. J. Wu, S. J. Chang, M. S. Chang, and C. Y. Hu. 2010. Exopolysaccharide activities from probiotic bifidobacterium: Immunomodulatory effects (on J774A.1 macrophages) and antimicrobial properties. International Journal of Food Microbiology 144 (1):104–10. doi: 10.1016/j.ijfoodmicro.2010.09.003.
   PubMed Web of Science ®Google Scholar
• Xie, N., Y. Wang, Q. Wang, F. Li, and B. Guo. 2012. Lipoteichoic acid of Bifidobacterium in combination with 5-fluorouracil inhibit tumor growth and relieve the immunosuppression. Bulletin du Cancer 99 (5):E55–E63. doi: 10.1684/bdc.2012.1571.
   PubMed Web of Science ®Google Scholar
• Yan, D.-C., C.-H. Hung, L. B. Sy, K.-H. Lue, I.-H. Shih, C.-Y. Yang, L.-C. Chen, H.-L. Sun, M.-S. Lee, J. Chambard, et al. 2019. A randomized, double-blind, placebo-controlled trial assessing the oral administration of a heat-treated Lactobacillus paracasei supplement in infants with atopic dermatitis receiving topical corticosteroid therapy. Skin Pharmacology and Physiology 32 (4):201–11. doi: 10.1159/000499436.
   PubMed Web of Science ®Google Scholar
• Yang, H. L., H. Q. Xia, Y. D. Ye, W. C. Zou, and Y. Z. Sun. 2014. Probiotic Bacillus pumilus SE5 shapes the intestinal microbiota and mucosal immunity in grouper Epinephelus coioides. Diseases of Aquatic Organisms 111 (2):119–27. doi: 10.3354/dao02772.
   PubMed Web of Science ®Google Scholar
• Yoshida, Y., T. Seki, H. Matsunaka, T. Watanabe, M. Shindo, N. Yamada, and O. Yamamoto. 2010. Clinical effects of probiotic Bifidobacterium breve supplementation in adult patients with atopic dermatitis. Yonago Acta Medica 53:37–45.
   Web of Science ®Google Scholar
• Yuk, H. G., and D. J. Geveke. 2011. Nonthermal inactivation and sublethal injury of Lactobacillus plantarum in apple cider by a pilot plant scale continuous supercritical carbon dioxide system. Food Microbiology 28 (3):377–83. doi: 10.1016/j.fm.2010.09.010.
   PubMed Web of Science ®Google Scholar
• Zhang, Y. C., L. W. Zhang, Y. F. Tuo, C. F. Guo, H. X. Yi, J. Y. Li, X. Han, and M. Du. 2010. Inhibition of Shigella sonnei adherence to HT-29 cells by Lactobacilli from Chinese fermented food and preliminary characterization of S-layer protein involvement. Research in Microbiology 161 (8):667–72. doi: 10.1016/j.resmic.2010.06.005.
   PubMed Web of Science ®Google Scholar
• Zhang, B., F. Zuo, R. Yu, Z. Zeng, H. Ma, and S. Chen. 2015. Comparative genome-based identification of a cell wall-anchored protein from Lactobacillus plantarum increases adhesion of Lactococcus lactis to human epithelial cells. Scientific Reports 5:14109. doi: 10.1038/srep14109.
   PubMed Web of Science ®Google Scholar