Effect of β-alanine and sodium bicarbonate co-supplementation on the body’s buffering capacity and sports performance: A systematic review

References

• Adrogué, H. J., and N. E. Madias. 1998. Management of Life-Threatening acid-base disorders. Second of two parts. The New England Journal of Medicine 338 (2):107–11. doi: 10.1056/NEJM199801083380207.
   PubMed Web of Science ®Google Scholar
• Aoi, W., and Y. Marunaka. 2014. Importance of PH homeostasis in metabolic health and diseases: crucial role of membrane proton transport. BioMed Research International 2014:598986–8. doi: 10.1155/2014/598986.
   PubMed Web of Science ®Google Scholar
• Artioli, G. G., B. Gualano, A. Smith, J. Stout, and A. H. J. Lancha. 2010. Role of beta-alanine supplementation on muscle carnosine and exercise performance. Medicine and Science in Sports and Exercise 42 (6):1162–73. doi: 10.1249/MSS.0b013e3181c74e38.
   PubMed Web of Science ®Google Scholar
• Australian Institute of 2021. Sport. Australian Institute of Sport Position Statement: Supplements and Sports Foods in High Performance Sport. Canberra. https://www.ais.gov.au/__data/assets/pdf_file/0014/1000841/Position-Statement-Supplements-and-Sports-Foods-abridged_v2.pdf.
   Google Scholar
• Bellinger, P. M., S. T. Howe, C. M. Shing, and J. W. Fell. 2012. Effect of combined β-alanine and sodiumbicarbonate supplementation on cycling performance. Medicine & Science in Sports & Exercise 44 (8):1545–51. doi: 10.1249/MSS.0b013e31824cc08d.
   PubMed Web of Science ®Google Scholar
• Bishop, D., J. Edge, C. Davis, and C. Goodman. 2004. Induced metabolic alkalosis affects muscle metabolism and repeated-sprint ability. Medicine and Science in Sports and Exercise 36 (5):807–13. 10.1249/01.MSS.0000126392.20025.17.
   PubMed Web of Science ®Google Scholar
• Caicoya, G., and M. Ángel. 2003. The effect of ingestion of sodium bicarbonate on lactate and athletic performance in the ran repeated series of 300 M. Revista Internacional de Medicina y Ciencias de La Actividad Física y El Deporte 3 (10):112–24. http://cdeporte.rediris.es/revista/revista10/artbicarbonato.html.
   Google Scholar
• Calbet, J. A. L., S. Martín-Rodríguez, M. Martin-Rincon, and D. Morales-Alamo. 2020. An integrative approach to the regulation of mitochondrial respiration during exercise: focus on high-intensity exercise. Redox Biology 35:101478–10. doi: 10.1016/j.redox.2020.101478.
   PubMed Web of Science ®Google Scholar
• Calvo, J. L., H. Xu, D. Mon-López, H. Pareja-Galeano, and S. L. Jiménez. 2021. Effect of sodium bicarbonate contribution on energy metabolism during exercise: a systematic review and meta-analysis. Journal of the International Society of Sports Nutrition 18 (1):11–7. (December):. doi: 10.1186/s12970-021-00410-y.
   PubMed Web of Science ®Google Scholar
• Carr, A. J., W. G. Hopkins, and C. J. Gore. 2011. Effects of acute alkalosis and acidosis on performance: a meta-analysis. Sports Medicine (Auckland, N.Z.) 41 (10):801–14. doi: 10.2165/11591440-000000000-00000.
   PubMed Web of Science ®Google Scholar
• Carr, A. J., G. J. Slater, C. J. Gore, B. Dawson, and L. M. Burke. 2011. Effect of sodium bicarbonate on [HCO3-], pH, and gastrointestinal symptoms. International Journal of Sport Nutrition and Exercise Metabolism 21 (3):189–94. doi: 10.1123/ijsnem.21.3.189.
   PubMed Web of Science ®Google Scholar
• Danaher, J., T. Gerber, R. M. Wellard, and C. G. Stathis. 2014. The effect of β-alanine and NaHCO3 co-ingestion on buffering capacity and exercise performance with high-intensity exercise in healthy males. European Journal of Applied Physiology 114 (8):1715–24. doi: 10.1007/s00421-014-2895-9.
   PubMed Web of Science ®Google Scholar
• De Salles Painelli, V.’, H. Roschel, F. de Jesus, C. Sale, R. C. Harris, M. Y. Solis, F. B. Benatti, B. Gualano, A. H. Lancha, and G. G. Artioli. 2013. The ergogenic effect of beta-alanine combined with sodium bicarbonate on high-intensity swimming performance. Applied Physiology, Nutrition, and Metabolism 38 (5):525–32. doi: 10.1139/apnm-2012-0286.
   PubMed Web of Science ®Google Scholar
• Décombaz, J., M. Beaumont, J. Vuichoud, F. Bouisset, and T. Stellingwerff. 2012. Effect of slow-release β-alanine tablets on absorption kinetics and paresthesia. Amino Acids. 43 (1):67–76. doi: 10.1007/s00726-011-1169-7.
   PubMed Web of Science ®Google Scholar
• Dennig, H., J. H. Talbott, H. T. Edwards, and D. B. Dill. 1931. Effect of acidosis and alkalosis upon capacity for work. The Journal of Clinical Investigation 9 (4):601–13. doi: 10.1172/JCI100324.
   PubMedGoogle Scholar
• Derave, W., I. Everaert, S. Beeckman, and A. Baguet. 2010. Muscle carnosine metabolism and β-alanine supplementation in relation to exercise and training. Sports Medicine 40 (3):247–63. doi: 10.2165/11530310-000000000-00000.
   PubMed Web of Science ®Google Scholar
• Dolan, E., P. A. Swinton, V. D. S. Painelli, B. Stephens Hemingway, B. Mazzolani, F. Infante Smaira, B. Saunders, G. G. Artioli, and B. Gualano. 2019. A systematic risk assessment and meta-analysis on the use of oral β-alanine supplementation. Advances in Nutrition (Bethesda, Md.) 10 (3):452–63. doi: 10.1093/advances/nmy115.
   PubMed Web of Science ®Google Scholar
• Domínguez, R., J. H. Lougedo, J. Luis Maté-Muñoz, and M. V. Garnacho-Castaño. 2015. Efectos de La Suplementación Con SS-Alanina Sobre El Rendimiento Deportivo. Nutricion Hospitalaria 31 (1):155–69. doi: 10.3305/nh.2015.31.1.7517.
   Google Scholar
• Ducker, K. J., B. Dawson, and K. E. Wallman. 2013. Effect of beta alanine and sodium bicarbonate supplementation on repeated-sprint performance. Journal of Strength and Conditioning Research 27 (12):3450–60. doi: 10.1519/JSC.0b013e31828fd310.
   PubMed Web of Science ®Google Scholar
• Grgic, J., Z. Pedisic, B. Saunders, G. G. Artioli, B. J. Schoenfeld, M. J. McKenna, D. J. Bishop, R. B. Kreider, J. R. Stout, D. S. Kalman, et al. 2021. International society of sports nutrition position stand: sodium bicarbonate and exercise performance. Journal of the International Society of Sports Nutrition 18 (1):61. doi: 10.1186/s12970-021-00458-w.
   PubMed Web of Science ®Google Scholar
• Hadzic, M., M. L. Eckstein, and M. Schugardt. 2019. The impact of sodium bicarbonate on performance in response to exercise duration in athletes: a systematic review. Journal of Sports Science & Medicine 18 (2):271–81.
   PubMed Web of Science ®Google Scholar
• Hobson, R. M., R. C. Harris, D. Martin, P. Smith, B. Macklin, B. Gualano, and C. Sale. 2013. Effect of beta-alanine, with and without sodium bicarbonate, on 2000-m rowing performance. International Journal of Sport Nutrition and Exercise Metabolism 23 (5):480–7. doi: 10.1123/ijsnem.23.5.480.
   PubMed Web of Science ®Google Scholar
• Jones, R. L., C. T. Barnett, J. Davidson, B. Maritza, W. D. Fraser, R. Harris, and C. Sale. 2017. β-Alanine supplementation improves in-vivo fresh and fatigued skeletal muscle relaxation speed. European Journal of Applied Physiology 117 (5):867–79. doi: 10.1007/s00421-017-3569-1.
   PubMed Web of Science ®Google Scholar
• Kahle, L. E., P. V. Kelly, K. A. Eliot, and E. P. Weiss. 2013. Acute sodium bicarbonate loading has negligible effects on resting and exercise blood pressure but causes gastrointestinal distress. Nutrition Research 33 (6):479–86. doi: 10.1016/j.nutres.2013.04.009.
   PubMed Web of Science ®Google Scholar
• Kerksick, C. M., C. D. Wilborn, M. D. Roberts, A. Smith-Ryan, S. M. Kleiner, R. Jäger, R. Collins, M. Cooke, J. N. Davis, E. Galvan, et al. 2018. ISSN exercise & sports nutrition review update: research & recommendations. Journal of the International Society of Sports Nutrition 15 (1):1–57. doi: 10.1186/s12970-018-0242-y.
   PubMed Web of Science ®Google Scholar
• Lancha Junior, A. H., V. de Salles Painelli, B. Saunders, and G. G. Artioli. 2015. Nutritional strategies to modulate intracellular and extracellular buffering capacity during high-intensity exercise. Sports Medicine 45 (S1):71–81. (November):. doi: 10.1007/s40279-015-0397-5.
   PubMedGoogle Scholar
• Liu, Q., P. Sikand, C. Ma, Z. Tang, L. Han, Z. Li, S. Sun, R. H. LaMotte, and X. Dong. 2012. Mechanisms of itch evoked by β-alanine. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 32 (42):14532–7. doi: 10.1523/JNEUROSCI.3509-12.2012.
   PubMed Web of Science ®Google Scholar
• Lopes-Silva, J. P., R. Reale, and E. Franchini. 2019. Acute and chronic effect of sodium bicarbonate ingestion on wingate test performance: a systematic review and meta-analysis. Journal of Sports Sciences 37 (7):762–71. doi: 10.1080/02640414.2018.1524739.
   PubMed Web of Science ®Google Scholar
• Maughan, R. J., L. M. Burke, J. Dvorak, D. E. Larson-Meyer, P. Peeling, S. M. Phillips, E. S. Rawson, N. P. Walsh, I. Garthe, H. Geyer, et al. 2018. IOC consensus statement: dietary supplements and the high-performance athlete. International Journal of Sport Nutrition and Exercise Metabolism 28 (2):104–25. doi: 10.1123/ijsnem.2018-0020.
   PubMed Web of Science ®Google Scholar
• Mero, A. A., P. Hirvonen, J. Saarela, J. J. Hulmi, J. R. Hoffman, and J. R. Stout. 2013. Effect of sodium bicarbonate and beta-alanine supplementation on maximal sprint swimming. Journal of the International Society of Sports Nutrition 10 (1):1–9. doi: 10.1186/1550-2783-10-52.
   PubMedGoogle Scholar
• Moher, D., A. Liberati, J. Tetzlaff, and D. G. Altman. 2009. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Medicine 6 (7):e1000097–6. doi: 10.1371/journal.pmed.1000097.
   PubMed Web of Science ®Google Scholar
• Pires da Silva, R., L. F. de Oliveira, B. Saunders, C. de Andrade Kratz, V. de Salles Painelli, V. da Eira Silva, J. C. B. Marins, E. Franchini, B. Gualano, and G. G. Artioli. 2019. Effects of β-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids 51 (1):83–96. doi: 10.1007/s00726-018-2643-2.
   PubMed Web of Science ®Google Scholar
• Pizzorno, J. 2015. Acidosis: an old idea validated by new research. Integrative Medicine (Encinitas) 14 (1):8–12. http://www.ncbi.nlm.nih.gov/pubmed/26770125.
   Google Scholar
• Robergs, R. A., F. Ghiasvand, and D. Parker. 2004. Biochemistry of exercise-induced metabolic acidosis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology 287 (3):R502–16. doi: 10.1152/ajpregu.00114.2004.
   PubMed Web of Science ®Google Scholar
• Sale, C., B. Saunders, S. Hudson, J. A. Wise, R. C. Harris, and C. D. Sunderland. 2011. Effect of β-alanine plus sodium bicarbonate on high-intensity cycling capacity. Medicine and Science in Sports and Exercise 43 (10):1972–8. doi: 10.1249/MSS.0b013e3182188501.
   PubMed Web of Science ®Google Scholar
• Saunders, B., K. Elliott-Sale, G. G. Artioli, P. A. Swinton, E. Dolan, H. Roschel, C. Sale, and B. Gualano. 2017. β-Alanine supplementation to improve exercise capacity and performance: a systematic review and meta-analysis. British Journal of Sports Medicine 51 (8):658–69. doi: 10.1136/bjsports-2016-096396.
   PubMed Web of Science ®Google Scholar
• Senewiratne, N. L., A. Woodall, and A. S. Can. 2021. Sodium bicarbonate. StatPearls. StatPearls Publishing. http://www.ncbi.nlm.nih.gov/pubmed/32644565.
   Google Scholar
• Tobias, G., F. B. Benatti, V. de Salles Painelli, H. Roschel, B. Gualano, C. Sale, R. C. Harris, A. H. Lancha, and G. G. Artioli. 2013. Additive effects of beta-alanine and sodium bicarbonate on upper-body intermittent performance. Amino Acids. 45 (2):309–17. doi: 10.1007/s00726-013-1495-z.
   PubMed Web of Science ®Google Scholar
• Trexler, E. T., A. E. Smith-Ryan, J. R. Stout, J. R. Hoffman, C. D. Wilborn, C. Sale, R. B. Kreider, R. Jäger, C. P. Earnest, L. Bannock, et al. 2015. International society of sports nutrition position stand: beta-alanine. Journal of the International Society of Sports Nutrition 12 (1):1–14. doi: 10.1186/s12970-015-0090-y.
   PubMed Web of Science ®Google Scholar