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Review Articles

Natural carriers: Recent advances in their use to improve the stability and bioaccessibility of food active compounds

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References

  • Acevedo-Guevara, L., L. Nieto-Suaza, L. T. Sanchez, M. I. Pinzon, and C. C. Villa. 2018. Development of native and modified banana starch nanoparticles as vehicles for curcumin. International Journal of Biological Macromolecules 111:498–504. doi: 10.1016/j.ijbiomac.2018.01.063.
  • Alhakamy, N. A., S. M. Badr-Eldin, U. A. Fahmy, N. K. Alruwaili, Z. A. Awan, G. Caruso, M. A. Alfaleh, A. L. Alaofi, F. O. Arif, O. A. A. Ahmed, et al. 2020. Thymoquinone-loaded soy-phospholipid-based phytosomes exhibit anticancer potential against human lung cancer cells. Pharmaceutics 12 (8):761. doi: 10.3390/pharmaceutics12080761.
  • Amalraj, A., S. Gopi, S. Thomas, and J. T. Haponiuk. 2018. Cellulose nanomaterials in biomedical, food, and nutraceutical applications: A review. Macromolecular Symposia 380 (1):1800115. doi: 10.1002/masy.201800115.
  • Anema, S. G. 2018. Spontaneous interaction of lactoferrin with casein micelles or individual caseins. Journal of the Royal Society of New Zealand 48 (2–3):89–110. doi: 10.1080/03036758.2018.1439846.
  • Ariyarathna, I. R., and D. N. Karunaratne. 2015. Use of chickpea protein for encapsulation of folate to enhance nutritional potency and stability. Food and Bioproducts Processing 95:76–82. doi: 10.1016/j.fbp.2015.04.004.
  • Arranz, E., M. Villalva, A. Guri, E. Ortego-Hernández, L. Jaime, G. Reglero, S. Santoyo, and M. Corredig. 2019. Protein matrices ensure safe and functional delivery of rosmarinic acid from marjoram (Origanum majorana) extracts. Journal of the Science of Food and Agriculture 99 (5):2629–35. doi: 10.1002/jsfa.9483.
  • Asabuwa Ngwabebhoh, F., S. Ilkar Erdagi, and U. Yildiz. 2018. Pickering emulsions stabilized nanocellulosic-based nanoparticles for coumarin and curcumin nanoencapsulations: In vitro release, anticancer and antimicrobial activities. Carbohydrate Polymers 201:317–28. doi: 10.1016/j.carbpol.2018.08.079.
  • Azizi, M., A. Kierulf, M. C. Lee, and A. Abbaspourrad. 2018. Improvement of physicochemical properties of encapsulated echium oil using nanostructured lipid carriers. Food Chemistry 246:448–56. doi: 10.1016/j.foodchem.2017.12.009l.
  • Bankole, V. O., M. O. Osungunna, C. R. F. Souza, S. L. Salvador, and W. P. Oliveira. 2020. Spray-dried proliposomes: An innovative method for encapsulation of Rosmarinus officinalis L. polyphenols. AAPS PharmSciTech 21 (5):143. doi: 10.1208/s12249-020-01668-2l.
  • Barak, S., and D. Mudgil. 2014. Locust bean gum: Processing, properties and food applications-A review. International Journal of Biological Macromolecules 66:74–80. doi: 10.1016/j.ijbiomac.2014.02.017.
  • Caddeo, C., M. Gabriele, A. Nácher, X. Fernàndez-Busquets, D. Valenti, A. M. Fadda, L. Pucci, and M. Manconi. 2021. Resveratrol and artemisinin eudragit-coated liposomes: A strategy to tackle intestinal tumors. International Journal of Pharmaceutics 592:120083. doi: 10.1016/j.ijpharm.2020.120083.
  • Campos, E. V. R., J. L. de Oliveira, L. F. Fraceto, and B. Singh. 2015. Polysaccharides as safer release systems for agrochemicals. Agronomy for Sustainable Development 35 (1):47–66. doi: 10.1007/s13593-014-0263-0.
  • Chamizo-González, F., B. Gordillo, and F. J. Heredia. 2021. Elucidation of the 3D structure of grape seed 7S globulin and its interaction with malvidin 3-glucoside: A molecular modeling approach. Food Chemistry 347:129014. doi: 10.1016/j.foodchem.2021.129014.
  • Chaves, M. A., and S. C. Pinho. 2020. Unpurified soybean lecithins impact on the chemistry of proliposomes and liposome dispersions encapsulating vitamin D3. Food Bioscience 37:100700. doi: 10.1016/j.fbio.2020.100700.
  • Chen, F. P., S. Y. Ou, Z. Chen, and C. H. Tang. 2017. Soy soluble polysaccharide as a nanocarrier for curcumin. Journal of Agricultural and Food Chemistry 65 (8):1707–14. doi: 10.1021/acs.jafc.6b05087.
  • Chen, F.-P., S.-Y. Ou, and C.-H. Tang. 2016. Core − shell soy protein − soy polysaccharide complex (nano)particles as carriers for improved stability and sustained release of curcumin. Journal of Agricultural and Food Chemistry 64 (24):5053–9. doi: 10.1021/acs.jafc.6b01176.
  • Chen, W., X. Ju, R. E. Aluko, Y. Zou, Z. Wang, M. Liu, and R. He. 2020. Rice bran protein-based nanoemulsion carrier for improving stability and bioavailability of quercetin. Food Hydrocolloids. 108:106042. doi: 10.1016/j.foodhyd.2020.106042.
  • Chin, S. F., S. N. A. Mohd Yazid, and S. C. Pang. 2014. Preparation and characterization of starch nanoparticles for controlled release of curcumin. International Journal of Polymer Science, 340121 2014:1–8. doi: 10.1155/2014/340121.
  • Cohen, Y., M. Levi, U. Lesmes, M. Margier, E. Reboul, and Y. D. Livney. 2017. Re-assembled casein micelles improve in vitro bioavailability of vitamin D in a Caco-2 cell model. Food & Function 8 (6):2133–41. doi: 10.1039/c7fo00323d.
  • Dai, T., R. Li, C. Liu, W. Liu, T. Li, J. Chen, M. Kharat, and D. J. McClements. 2019. Effect of rice glutelin-resveratrol interactions on the formation and stability of emulsions: A multiphotonic spectroscopy and molecular docking study. Food Hydrocolloids. 97:105234. doi: 10.1016/j.foodhyd.2019.105234.
  • Dai, T., X. Yan, Q. Li, T. Li, C. Liu, D. J. McClements, and J. Chen. 2017. Characterization of binding interaction between rice glutelin and gallic acid: Multi-spectroscopic analyses and computational docking simulation. Food Research International (Ottawa, Ont.) 102:274–81. doi: 10.1016/j.foodres.2017.09.020.
  • Danaei, M., M. Kalantari, M. Raji, H. S. Samareh Fekri, R. Saber, G. P. Asnani, S. M. Mortazavi, M. R. Mozafari, B. Rasti, and A. Taheriazam. 2018. Probing nanoliposomes using single particle analytical techniques: Effect of excipients, solvents, phase transition and zeta potential. Heliyon 4 (12):e01088. doi: 10.1016/j.heliyon.2018.e01088.
  • Davidov-Pardo, G., I. J. Joye, and D. J. McClements. 2015. Encapsulation of resveratrol in biopolymer particles produced using liquid antisolvent precipitation. Part 1: Preparation and characterization. Food Hydrocolloids. 45:309–16. doi: 10.1016/j.foodhyd.2014.11.023.
  • Deladino, L., A. S. Teixeira, A. S. Navarro, I. Alvarez, A. D. Molina-García, and M. Martino. 2015. Corn starch systems as carriers for yerba mate (Ilex paraguariensis) antioxidants. Food and Bioproducts Processing 94:463–72. doi: 10.1016/j.fbp.2014.07.001.
  • Delfanian, M., S. M. A. Razavi, M. H. Haddad Khodaparast, R. Esmaeilzadeh Kenari, and S. Golmohammadzadeh. 2018. Influence of main emulsion components on the physicochemical and functional properties of W/O/W nano-emulsion: Effect of polyphenols, Hi-Cap, basil seed gum, soy and whey protein isolates. Food Research International (Ottawa, Ont.) 108:136–43. doi: 10.1016/j.foodres.2018.03.043.
  • Di Pede, G., L. Bresciani, L. Calani, G. Petrangolini, A. Riva, P. Allegrini, D. D. Rio, and P. Mena. 2020. The human microbial metabolism of quercetin in different formulations: An in vitro evaluation. Foods 9 (8):1121. doi: 10.3390/foods9081121.
  • Dib, T., H. Pan, and S. Chen. 2022. Recent advances in pectin-based nanoencapsulation for enhancing the bioavailability of bioactive compounds: Curcumin oral bioavailability. Food Reviews International, :1–19. doi: 10.1080/87559129.2021.2012796.
  • Edelman, R., S. Engelberg, L. Fahoum, E. G. Meyron-Holtz, and Y. D. Livney. 2019. Potato protein- based carriers for enhancing bioavailability of astaxanthin. Food Hydrocolloids. 96:72–80. doi: 10.1016/j.foodhyd.2019.04.058.
  • El-Fattah, A. I. A., M. M. Fathy, Z. Y. Ali, A. E.-R A. El-Garawany, and E. K. Mohamed. 2017. Enhanced therapeutic benefit of quercetin-loaded phytosome nanoparticles in ovariectomized rats. Chemico-Biological Interactions 271:30–8. doi: 10.1016/j.cbi.2017.04.026.
  • Fathi, M., Á. Martín, and D. J. McClements. 2014. Nanoencapsulation of food ingredients using carbohydrate based delivery systems. Trends in Food Science & Technology 39 (1):18–39. doi: 10.1016/j.tifs.2014.06.007.
  • Fathima, S. J., I. Fathima, V. Abhishek, and F. Khanum. 2016. Phosphatidylcholine, an edible carrier for nanoencapsulation of unstable thiamine. Food Chemistry 197 (Pt A):562–70. doi: 10.1016/j.foodchem.2015.11.005.
  • Ferron, L., C. Milanese, R. Colombo, R. Pugliese, and A. Papetti. 2022a. Selection and optimization of an innovative polysaccharide-based carrier to improve anthocyanins stability in purple corn cob extracts. Antioxidants 11 (5):916. doi: 10.3390/antiox11050916.
  • Ferron, L., C. Milanese, R. Colombo, R. Pugliese, and A. Papetti. 2022b. A new polysaccharide carrier isolated from camelina cake: Structural characterization. Rheological behaviour, and its influence on purple corn cob extract’s bioaccessibility. Foods 11 (12):1736. doi: 10.3390/foods11121736.
  • George, A., P. A. Shah, and P. S. Shrivastav. 2019. Guar gum: Versatile natural polymer for drug delivery applications. European Polymer Journal 112:722–35. doi: 10.1016/j.eurpolymj.2018.10.042.
  • Ghanbarzadeh, B., A. Babazadeh, and H. Hamishehkar. 2016. Nano-phytosome as a potential food-grade delivery system. Food Bioscience 15:126–35. doi: 10.1016/j.fbio.2016.07.006.
  • Goëlo, V., M. Chaumun, A. Gonçalves, B. N. Estevinho, and F. Rocha. 2020. Polysaccharide-based delivery systems for curcumin and turmeric powder encapsulation using a spray-drying process. Powder Technology 370:137–46. doi: 10.1016/j.powtec.2020.05.016.
  • Gomes, A., G. de Figueiredo Furtado, F., and R. L. Cunha. 2019. Bioaccessibility of lipophilic compounds vehiculated in emulsions: Choice of lipids and emulsifiers. Journal of Agricultural and Food Chemistry 67 (1):13–8. doi: 10.1021/acs.jafc.8b05460.
  • Gong, K.-J., A.-M. Shi, H.-Z. Liu, L. Liu, H. Hu, Y. Yang, B. Adhikari, and Q. Wang. 2016. Preparation of nanoliposome loaded with peanut peptide fraction: Stability and bioavailability. Food & Function 7 (4):2034–42. doi: 10.1039/c5fo01612f.
  • Gopi, S., and P. Balakrishnan. 2021. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. Journal of Liposome Research 31 (4):356–64. doi: 10.1080/08982104.2020.1820521.
  • Gupta, N., A. K. Jangid, D. Pooja, and H. Kulhari. 2019. Inulin: A novel and stretchy polysaccharide tool for biomedical and nutritional applications. International Journal of Biological Macromolecules 132:852–63. doi: 10.1016/j.ijbiomac.2019.03.188.
  • Hamadou, A. H., W.-C. Huang, C. Xue, and X. Mao. 2020. Formulation of vitamin C encapsulation in marine phospholipids nanoliposomes: Characterization and stability evaluation during long term storage. LWT 127:109439. doi: 10.1016/j.lwt.2020.109439.
  • Hasanvand, E., M. Fathi, and A. Bassiri. 2018. Production and characterization of vitamin D3 loaded starch nanoparticles: Effect of amylose to amylopectin ratio and sonication parameters. Journal of Food Science and Technology 55 (4):1314–24. doi: 10.1007/s13197-018-3042-0.
  • Hashemi Gahruie, H., E. Ziaee, M. H. Eskandari, and S. M. H. Hosseini. 2017. Characterization of basil seed gum-based edible films incorporated with Zataria multiflora essential oil nanoemulsion. Carbohydrate Polymers 166:93–103. doi: 10.1016/j.carbpol.2017.02.103.
  • He, X., W. Lu, C. Sun, H. Khalesi, A. Mata, R. Andaleeb, and Y. Fang. 2021. Cellulose and cellulose derivatives: Different colloidal states and food-related applications. Carbohydrate Polymers 255:117334. doi: 10.1016/j.carbpol.2020.117334.
  • Herculano, E. D., H. C. B. de Paula, E. A. T. de Figueiredo, F. G. B. Dias, and V. d A. Pereira. 2015. Physicochemical and antimicrobial properties of nanoencapsulated Eucalyptus staigeriana essential oil. LWT - Food Science and Technology 61 (2):484–91. doi: 10.1016/j.lwt.2014.12.001.
  • Hosny, K. M., A. M. Sindi, S. Ali, W. S. Alharbi, M. S. Hajjaj, H. A. Bukhary, M. Y. Badr, R. Y. Mushtaq, S. S. A. Murshid, A. M. Almehmady, et al. 2022. Development, optimization, and evaluation of a nanostructured lipid carrier of sesame oil loaded with miconazole for the treatment of oral candidiasis. Drug Delivery 29 (1):254–62. doi: 10.1080/10717544.2021.2023703.
  • Hsu, C.-Y., P.-W. Wang, A. Alalaiwe, Z.-C. Lin, and J.-Y. Fang. 2019. Use of lipid nanocarriers to improve oral delivery of vitamins. Nutrients 11 (1):68. doi: https://doi.org/10.3390/nu11010068.
  • Hu, Q., H. Gerhard, I. Upadhyaya, K. Venkitanarayanan, and Y. Luo. 2016. Antimicrobial eugenol nanoemulsion prepared by gum arabic and lecithin and evaluation of drying technologies. International Journal of Biological Macromolecules 87:130–40. doi: 10.1016/j.ijbiomac.2016.02.051.
  • Hu, Y., W. Zhang, Z. Ke, Y. Li, and Z. Zhou. 2017. In vitro release and antioxidant activity of Satsuma mandarin (Citrus reticulata Blanco cv. unshiu) peel flavonoids encapsulated by pectin nanoparticles. International Journal of Food Science & Technology 52 (11):2362–73. doi: 10.1111/ijfs.13520.
  • Huang, S., X. Liu, C. Chang, and Y. Wang. 2020. Recent developments and prospective food-related applications of cellulose nanocrystals: A review. Cellulose 27 (6):2991–3011. doi: 10.1007/s10570-020-02984-3.
  • Huang, Z., C. S. Brennan, H. Zhao, J. Liu, W. Guan, M. S. Mohan, L. Stipkovits, H. Zheng, and D. Kulasiri. 2020. Fabrication and assessment of milk phospholipid-complexed antioxidant phytosomes with vitamin C and E: A comparison with liposomes. Food Chemistry 324:126837. doi: 10.1016/j.foodchem.2020.126837.
  • Hudiyanti, D., N. I. Hamidi, D. S. B. Anugrah, S. N. M. Salimah, and P. Siahaan. 2019. Encapsulation of vitamin C in sesame liposomes: Computational and experimental studies. Open Chemistry 17 (1):537–43. doi: 10.1515/chem-2019-006.
  • Huguet-Casquero, A., M. Moreno-Sastre, T. B. López-Méndez, E. Gainza, and J. L. Pedraz. 2020. Encapsulation of oleuropein in nanostructured lipid carriers: Biocompatibility and antioxidant efficacy in lung epithelial cells. Pharmaceutics 12 (5):429. doi: 10.3390/pharmaceutics12050429.
  • Huq, T., C. Fraschini, A. Khan, B. Riedl, J. Bouchard, and M. Lacroix. 2017. Alginate based nanocomposite for microencapsulation of probiotic: Effect of cellulose nanocrystal (CNC) and lecithin. Carbohydrate Polymers 168:61–9. doi: 10.1016/j.carbpol.2017.03.032.
  • Jain, A., S. K. Singh, S. K. Arya, S. C. Kundu, and S. Kapoor. 2018. Protein nanoparticles: Promising platforms for drug delivery applications. ACS Biomaterials Science & Engineering 4 (12):3939–61. doi: 10.1021/acsbiomaterials.8b01098.
  • Kasaai, M. R. 2018. Zein and zein -based nano-materials for food and nutrition applications; A review. Trends in Food Science & Technology 79:184–97. doi: 10.1016/j.tifs.2018.07.015.
  • Khan, W. A., M. S. Butt, I. Pasha, and A. Jamil. 2020. Microencapsulation of vitamin D in protein matrices: In vitro release and storage stability. Journal of Food Measurement and Characterization 14 (3):1172–82. doi: 10.1007/s11694-019-00366-3.
  • Khoshakhlagh, K., A. Koocheki, M. Mohebbi, and A. Allafchian. 2017. Development and characterization of electrosprayed Alyssum homolocarpum seed gum nanoparticles for encapsulation of D-limonene. Journal of Colloid and Interface Science 490:562–75. doi: 10.1016/j.jcis.2016.11.067.
  • Kim, J. Y., and K. C. Huber. 2016. Preparation and characterization of corn starch-β-carotene composites. Carbohydrate Polymers 136:394–401. doi: 10.1016/j.carbpol.2015.08.069.
  • Kurd, F., M. Fathi, and H. Shekarchizadeh. 2017. Basil seed mucilage as a new source for electrospinning: Production and physicochemical characterization. International Journal of Biological Macromolecules 95:689–95. doi: 10.1016/j.ijbiomac.2016.11.116.
  • Kurek, M. A., and A. Pratap-Singh. 2020. Plant-based (hemp, pea and rice) protein–maltodextrin combinations as wall material for spray-drying microencapsulation of hempseed (Cannabis sativa) oil. Foods 9 (11):1707. doi: 10.3390/foods9111707.
  • Leibtag, S., and A. Peshkovsky. 2020. Cannabis extract nanoemulsions produced by high-intensity ultrasound: Formulation development and scale-up. Journal of Drug Delivery Science and Technology 60:101953. doi: 10.1016/j.jddst.2020.101953.
  • Li, H., D. Wang, c Liu, J. Zhu, M. Fan, X. Sun, T. Wang, Y. Xu, and Y. Cao. 2019. Fabrication of stable zein nanoparticles coated with soluble soybean polysaccharide for encapsulation of quercetin. Food Hydrocolloids. 87:342–51. doi: 10.1016/j.foodhyd.2018.08.002.
  • Li, H., Y. Yuan, J. Zhu, T. Wang, D. Wang, and Y. Xu. 2020. Zein/soluble soybean polysaccharide composite nanoparticles for encapsulation and oral delivery of lutein. Food Hydrocolloids. 103:105715. doi: 10.1016/j.foodhyd.2020.105715.
  • Li, J., and Z. Chen. 2022. Fabrication of heat-treated soybean protein isolate-EGCG complex nanoparticle as a functional carrier for curcumin. LWT 159:113059. doi: 10.1016/j.lwt.2021.113059.
  • Li, J., X. Xu, Z. Chen, T. Wang, Z. Lu, W. Hu, and L. Wang. 2018. Zein/gum Arabic nanoparticle-stabilized Pickering emulsion with thymol as an antibacterial delivery system. Carbohydrate Polymers 200:416–26. doi: 10.1016/j.carbpol.2018.08.025.
  • Links, M. R., J. Taylor, M. C. Kruger, V. Naidoo, and J. R. N. Taylor. 2016. Kafirin microparticle encapsulated sorghum condensed tannins exhibit potential as an anti-hyperglycaemic agent in a small animal model. Journal of Functional Foods 20:394–9. doi: 10.1016/j.jff.2015.11.015.
  • Liu, K., X.-L. Kong, Q.-M. Li, H.-L. Zhang, X.-Q. Zha, and J.-P. Luo. 2020. Stability and bioavailability of vitamin D3 encapsulated in composite gels of whey protein isolate and lotus root amylopectin. Carbohydrate Polymers 227:115337. doi: 10.1016/j.carbpol.2019.115337.
  • Liu, W., Y. Kong, P. Tu, J. Lu, C. Liu, W. Liu, J. Han, and J. Liu. 2017. Physical-chemical stability and in vitro digestibility of hybrid nanoparticles based on the layer-by-layer assembly of lactoferrin and BSA on liposomes. Food & Function 8 (4):1688–97. doi: 10.1039/c7fo00308k.
  • Lu, X., J. Chen, Z. Guo, Y. Zheng, M. C. Rea, H. Su, X. Zheng, B. Zheng, and S. Miao. 2019. Using polysaccharides for the enhancement of functionality of foods: A review. Trends in Food Science & Technology 86:311–27. doi: 10.1016/j.tifs.2019.02.024.
  • Łukawski, M., P. Dałek, T. Borowik, A. Foryś, M. Langner, W. Witkiewicz, and M. Przybyło. 2020. New oral liposomal vitamin C formulation: Properties and bioavailability. Journal of Liposome Research 30 (3):227–34. doi: 10.1080/08982104.2019.1630642.
  • Luo, Y., Q. Wang, and Y. Zhang. 2020. Biopolymer-based nanotechnology approaches to deliver bioactive compounds for food applications: A perspective on the past, present, and future. Journal of Agricultural and Food Chemistry 68 (46):12993–3000. doi: 10.1021/acs.jafc.0c00277.
  • Lv, S., J. Gu, R. Zhang, Y. Zhang, H. Tan, and D. J. McClements. 2018. Vitamin E encapsulation in plant-based nanoemulsions fabricated using dual-channel microfluidization: Formation, stability, and bioaccessibility. Journal of Agricultural and Food Chemistry 66 (40):10532–42. doi: 10.1021/acs.jafc.8b03077.
  • Mahmoodi, N., N. Motamed, S. H. Paylakhi, and N. O. Mahmoodi. 2015. Comparing the effect of silybin and silybin Advancedtm on viability and HER2 expression on the human breast cancer SKBR3 cell line by no serum starvation. Iranian Journal of Pharmaceutical Research : IJPR 14 (2):521–30. doi: 10.22037/IJPR.2015.1662.
  • Manzar, M. K., M. K. Pirouzifard, H. Hamishehkar, and S. Pirsa. 2020. Cocoa butter and cocoa butter substitute as a lipid carrier of Cuminum cyminum L. essential oil; physicochemical properties, physical stability and controlled release study. Journal of Molecular Liquids 314:113638. doi: 10.1016/j.molliq.2020.113638.
  • Majeed, H., J. Antoniou, J. Hategekimana, H. R. Sharif, J. Haider, F. Liu, B. Ali, L. Rong, J. Ma, and F. Zhong. 2016. Influence of carrier oil type, particle size on in vitro lipid digestion and eugenol release in emulsion and nanoemulsions. Food Hydrocolloids. 52:415–22. doi: 10.1016/j.foodhyd.2015.07.009.
  • Marín, D., A. Alemán, P. Montero, and M. C. Gómez-Guillén. 2018. Encapsulation of food waste compounds in soy phosphatidylcholine liposomes: Effect of freeze-drying, storage stability and functional aptitude. Journal of Food Engineering 223:132–43. doi: 10.1016/j.jfoodeng.2017.12.009.
  • Martínez, J. H., F. Velázquez, H. P. Burrieza, K. D. Martínez, A. P. Domínguez Rubio, C. dos Santos Ferreira, M. del Pilar Buera, and O. E. Pérez. 2019. Betanin loaded nanocarriers based on quinoa seed 11S globulin. Impact on the protein structure and antioxidant activity. Food Hydrocolloids. 87:880–90. doi: 10.1016/j.foodhyd.2018.09.016.
  • Marwaha, R. K., and A. Dabas. 2019. Bioavailability of nanoemulsion formulations vs conventional fat soluble preparations of cholecalciferol (D3)—An overview. Journal of Clinical Orthopaedics and Trauma 10 (6):1094–6. doi: 10.1016/j.jcot.2019.07.014.
  • Maviah, M. B. J., M. A. Farooq, R. Mavlyanova, H. Veroniaina, M. S. Filli, M. Aquib, S. Kesse, K. O. Boakye-Yiadom, and B. Wan. 2020. Food protein-based nanodelivery systems for hydrophobic and poorly soluble compounds. AAPS PharmSciTech 21 (3):101. doi: 10.1208/s12249-020-01641-z.
  • McClements, D. J. 2015. Nanoscale nutrient delivery systems for food applications: Improving bioactive dispersibility, stability, and bioavailability. Journal of Food Science 80 (7):N1602–N1611. doi: 10.1111/1750-3841.12919.
  • McClements, D. J., L. Saliva-Trujillo, R. Zhang, Z. Zhang, L. Zou, M. Yao, and H. Xiao. 2016. Boosting the bioavailability of hydrophobic nutrients, vitamins, and nutraceuticals in natural products using excipient emulsions. Food Research International (Ottawa, Ont.) 88 (Pt A):140–52. doi: 10.1016/j.foodres.2015.11.017.
  • McClements, D. L., and S. M. Jafari. 2017. Chapter one - Nanotechnology approaches for increasing nutreint bioavailability. Advances in Food and Nutrition Research 81:1–30. doi: 10.1016/bs.afnr.2016.12.008.
  • Mehanna, M. M., and A. T. Mneimneh. 2020. Updated but not outdated “Gliadin”: A plant protein in advanced pharmaceutical nanotechnologies. International Journal of Pharmaceutics 587:119672. doi: 10.1016/j.ijpharm.2020.119672.
  • Meng, Q., P. Long, J. Zhou, C.-T. Ho, X. Zou, B. Chen, and L. Zhang. 2019. Improved absorption of β-carotene by encapsulation in an oil-in-water nanoemulsion containing tea polyphenols in the aqueous phase. Food Research International 116:731–6. doi: 10.1016/j.foodres.2018.09.004.
  • Miranda, M., M. T. Cruz, C. Vitorino, and C. Cabral. 2019. Nanostructuring lipid carriers using Ridolfia segetum (L.) Moris essential oil. Materials Science & Engineering. C, Materials for Biological Applications 103:109804. doi: 10.1016/j.msec.2019.10980413.
  • Monaci, L., R. Pilolli, E. De Angelis, J. F. Crespo, N. Novak, and B. Cabanillas. 2020. Food allergens: Classification, molecular properties, characterization, and detection in food sources. Advances in Food and Nutrition Research 93:113–46. doi: 10.1016/bs.afnr.2020.03.001.
  • Moser, P., V. R. Nicoletti Telis, N. de Andrade Neves, E. García-Romero, S. Gómez-Alonso, and I. Hermosín-Gutiérrez. 2017. Storage stability of phenolic compounds in powdered BRS Violeta grape juice microencapsulated with protein and maltodextrin blends. Food Chemistry 214:308–18. doi: 10.1016/j.foodchem.2016.07.081.
  • Moser, P., R. T. D. Souza, and N. R. N. Telis. 2017. Spray drying of grape juice from Hybrid cv. brs violeta: Microencapsulation of anthocyanins using protein/maltodextrin blends as drying aids. Journal of Food Processing and Preservation 41 (1):e12852. doi: 10.1111/jfpp.12852.
  • Mu, R., X. Hong, Y. Ni, Y. Li, J. Pang, Q. Wang, J. Xiao, and Y. Zheng. 2019. Recent trends and applications of cellulose nanocrystals in food industry. Trends in Food Science & Technology 93:136–44. doi: 10.1016/j.tifs.2019.09.013.
  • Nahr, F. K., B. Ghanbarzadeh, H. Hamishehkar, and H. S. Kafil. 2018. Food grade nanostructured lipid carrier for cardamom essential oil: Preparation, characterization and antimicrobial activity. Journal of Functional Foods 40:1–8. doi: 10.1016/j.jff.2017.09.028.
  • Naji-Tabasi, S., S. M. A. Razavi, and H. Mehditabar. 2017. Fabrication of basil seed gum nanoparticles as a novel oral delivery system of glutathione. Carbohydrate Polymers 157:1703–13. doi: 10.1016/j.carbpol.2016.11.052.
  • Naqash, F., F. A. Masoodi, S. A. Rather, S. M. Wani, and A. Gani. 2017. Emerging concepts in the nutraceutical and functional properties of pectin—A Review. Carbohydrate Polymers 168:227–39. doi: 10.1016/j.carbpol.2017.03.058.
  • Nesterenko, A., I. Alric, F. Silvestre, and V. Durrieu. 2013. Vegetable proteins in microencapsulation: A review of recent interventions and their effectiveness. Industrial Crops and Products 42:469–79. doi: 10.1016/j.indcrop.2012.06.035.
  • Niknam, S. M., I. Escudero, and J. M. Benito. 2020. Formulation and preparation of water-in-oil-in-water emulsions loaded with a phenolic-rich inner aqueous phase by application of high energy emulsification methods. Foods 9 (10):1411. doi: 10.3390/foods9101411.
  • Noreen, A., Z. I. H. Nazli, J. Akram, I. Rasul, A. Mansha, N. Yaqoob, R. Iqbal, S. Tabasum, M. Zuber, and K. M. Zia. 2017. Pectins functionalized biomaterials; a new viable approach for biomedical applications: A review. International Journal of Biological Macromolecules 101:254–72. doi: 10.1016/j.ijbiomac.2017.03.029.
  • Nsor-Atindana, J., M. Chen, H. D. Goff, F. Zhong, H. R. Sharif, and Y. Li. 2017. Functionality and nutritional aspects of microcrystalline cellulose in food. Carbohydrate Polymers 172:159–74. doi: 10.1016/j.carbpol.2017.04.021.
  • Nunes, R., A. Baião, D. Monteiro, J. das Neves, and B. Sarmento. 2020. Zein nanoparticles as low-cost, safe, and effective carriers to improve the oral bioavailability of resveratrol. Drug Delivery and Translational Research 10 (3):826–37. doi: 10.1007/s13346-020-00738-z.
  • Olatunde, O. O., S. Benjakul, K. Vongkamjan, and T. Amnuaikit. 2020. Influence of stabilising agents on the properties of liposomal encapsulated ethanolic coconut husk extract. International Journal of Food Science & Technology 55 (2):702–11. doi: 10.1111/ijfs.14339.
  • O'Sullivan, J., B. Murray, B. Flynn, and I. Norton. 2016. The effect of ultrasound treatment on the structural, physical and emulsifying properties of animal and vegetable proteins. Food Hydrocolloids. 53:141–54. doi: 10.1016/j.foodhyd.2015.02.009.
  • Ozturk, B., S. Argin, M. Ozilgen, and D. J. McClements. 2015. Nanoemulsion delivery systems for oil-soluble vitamins: Influence of carrier oil type on lipid digestion and vitamin D3 bioaccessibility. Food Chemistry 187:499–506. doi: 10.1016/j.foodchem.2015.04.065.
  • Padma Ishwarya, S. Sandhya, R, and Nisha, P. 2022. Advances and prospects in the food application of pectin hydrogels. Critical Reviews in Food Science and Nutrition 62 (16):4393–417. doi: 10.1080/10408398.2021.1875394.
  • Pamunuwa, G., N. Anjalee, D. Kukulewa, C. Edirisinghe, F. Shakoor, and D. N. Karunaratne. 2020. Tailoring of release properties of folic acid encapsulated nanoparticles via changing alginate and pectin composition in the matrix. Carbohydrate Polymer Technologies and Applications 1:100008. doi: 10.1016/j.carpta.2020.100008.
  • Pan, K., H. Chen, S. J. Baek, and Q. Zhong. 2018. Self-assembled curcumin-soluble soybean polysaccharide nanoparticles: Physicochemical properties and in vitro anti-proliferation activity against cancer cells. Food Chemistry 246:82–9. doi: 10.1016/j.foodchem.2017.11.002.
  • Pan, Y., R. V. Tikekar, and N. Nitin. 2016. Distribution of a model bioactive within solid lipid nanoparticles and nanostructured lipid carriers influences its loading efficiency and oxidative stability. International Journal of Pharmaceutics 511 (1):322–30. doi: 10.1016/j.ijpharm.2016.07.019.
  • Parhizkar, E., M. Rashedinia, M. Karimi, and S. Alipour. 2018. Design and development of vitamin C-encapsulated proliposome with improved in-vitro and ex-vivo antioxidant efficacy. Journal of Microencapsulation 35 (3):301–11. doi: 10.1080/02652048.2018.1477845.
  • Peng, H., S. Chen, M. Luo, F. Ning, X. Zhu, and H. Xiong. 2016. Preparation and self-assembly mechanism of bovine serum albumin − citrus peel pectin conjugated hydrogel: A potential delivery system for vitamin C. Journal of Agricultural and Food Chemistry 64 (39):7377–84. doi: 10.1021/acs.jafc.6b02966.
  • Pérez-Masiá, R., R. López-Nicolás, M. J. Periago, G. Ros, J. M. Lagaron, and A. López-Rubio. 2015. Encapsulation of folic acid in food hydrocolloids through nanospray drying and electrospraying for nutraceutical applications. Food Chemistry 168:124–33. doi: 10.1016/j.foodchem.2014.07.051.
  • Pezeshki, A., H. Hamishehkar, B. Ghanbarzadeh, I. Fathollahy, F. K. Nahr, M. K. Heshmati, and M. Mohammadi. 2019. Nanostructured lipid carriers as a favorable delivery system for β-carotene. Food Bioscience 27:11–7. 7. doi: 10.1016/j.fbio.2018.11.004.
  • Pimentel-Moral, S., C. Rodríguez-Pérez, A. Segura-Carretero, and A. Martínez-Férez. 2018. Development and stability evaluation of water-in-edible oils emulsions formulated with the incorporation of hydrophilic Hibiscus sabdariffa extract. Food Chemistry 260:200–7. doi: 10.1016/j.foodchem.2018.03.146.
  • Qiu, C., B. Wang, Y. Wang, and Y. Teng. 2017. Effects of colloidal complexes formation between resveratrol and deamidated gliadin on the bioaccessibility and lipid oxidative stability. Food Hydrocolloids. 69:466–72. doi: 10.1016/j.foodhyd.2017.02.020.
  • Quiroz, J. Q., V. Velazquez, L. L. Corrales-Garcia, J. D. Torres, E. Delgado, G. Ciro, and J. Rojas. 2020. Use of plant proteins as microencapsulating agents of bioactive compounds extracted from annatto seeds (Bixa orellana L.). Antioxidants 9 (4):310. doi: 10.3390/antiox9040310.
  • Rasheed, F., J. Markgren, M. Hedenqvist, and E. Johansson. 2020. Modeling to understand plant protein structure-function relationships—implications for seed storage proteins. Molecules 25 (4):873. doi: 10.3390/molecules25040873.
  • Rehman, A., T. Ahmad, R. M. Aadil, M. J. Spotti, A. M. Bakry, I. M. Khan, L. Zhao, T. Riaz, and Q. Tong. 2019. Pectin polymers as wall materials for the nano-encapsulation of bioactive compounds. Trends in Food Science & Technology 90:35–46. doi: 10.1016/j.tifs.2019.05.015.
  • Ribas-Agustì, A., O. Martìn-Belloso, R. Soliva-Fortuny, and P. Elez-Martínez. 2018. Food processing strategies to enhance phenolic compounds bioaccessibility and bioavailability in plant-based foods. Critical Reviews in Food Science and Nutrition 58 (15):2531–48. doi: https://doi.org/10.1080/10408398.2017.1331200.
  • Riva, A., M. Ronchi, G. Petrangolini, S. Bosisio, and P. Allegrini. 2019. Improved oral absorption of quercetin from quercetin phytosome®, a new delivery system based on food grade lecithin. European Journal of Drug Metabolism and Pharmacokinetics 44 (2):169–77. doi: 10.1007/s13318-018-0517-3.
  • Rodríguez Robledo, V., and L. I. Castro Vázquez. 2020. Pectin - Extraction, Purification, Characterization and Applications. In M. A. Masuelli (Eds.), Pectins - Extraction, Purification, Characterization and Applications, 1–19. London, UK: ItechOpen. doi: 10.5772/intechopen.85588.
  • Rostamabadi, H., S. R. Falsafi, and S. M. Jafari. 2019. Starch-based nanocarriers as cutting-edge natural cargos for nutraceutical delivery. Trends in Food Science & Technology 88:397–415. doi: 10.1016/j.tifs.2019.04.004.
  • Salvia-Trujillo, L., R. Soliva-Fortuny, M. A. Rojas-Graü, D. J. McClements, and O. Martín-Belloso. 2017. Edible nanoemulsions as carriers of active ingredients: A review. Annual Review of Food Science and Technology 8:439–66. doi: 10.1146/annurev-food-030216-025908.
  • Sampathkumar, K., K. X. Tan, and C. S. J. Loo. 2020. Developing nano-delivery systems for agriculture and food applications with nature-derived polymers. iScience 23 (5):101055. doi: 10.1016/j.isci.2020.101055.
  • Sanchez, C., M. Nigen, V. Mejia Tamayo, T. Doco, P. Williams, C. Amine, and D. Renard. 2018. Acacia gum: History of the future. Food Hydrocolloids 78:140–60. doi: 10.1016/j.foodhyd.2017.04.008.
  • Santoyo-Aleman, D., L. T. Sanchez, and C. C. Villa. 2019. Citric-acid modified banana starch nanoparticles as a novel vehicle for β-carotene delivery. Journal of the Science of Food and Agriculture 99 (14):6392–9. doi: 10.1002/jsfa.9918.
  • Schoener, A. L., R. Zhang, S. Lv, J. Weiss, and D. J. McClements. 2019. Fabrication of plant-based vitamin D3-fortified nanoemulsions: Influence of carrier oil type on vitamin bioaccessibility. Food & Function 10 (4):1826–35. doi: 10.1039/c9fo00116f.
  • Sharma, G., S. Sharma, A. Kumar, A. H. Al-Muhtaseb, M. Naushad, A. A. Ghfar, G. T. Mola, and F. Stadler. 2018. Guar gum and its composites as potential material for diverse applications: A review. Carbohydrate Polymers 199:534–45. doi: 10.1016/j.carbpol.2018.07.053.
  • Silva, E. K., Zabot, G. L. Bargas, M. A. Meireles, and M. A. A. 2016. Microencapsulation of lipophilic bioactive compounds using prebiotic carbohydrates: Effect of the degree of inulin polymerization. Carbohydrate Polymers 152:775–83. doi: 10.1016/j.carbpol.2016.07.066.
  • Singh, N., P. Kushwaha, U. Ahmad, and M. Abdullah. 2019. Proliposomes: An approach for the development of stable liposome. Ars Pharmaceutica (Internet) 60 (4):231–40. doi: 10.30827/ars.v60i4.8517.
  • Sinisgalli, C., I. Faraone, A. Vassallo, C. Caddeo, F. Bisaccia, M. F. Armentano, L. Milella, and A. Ostuni. 2020. Phytochemical profile of Capsicum annuum L. cv Senise, Incorporation into liposomes, and evaluation of cellular antioxidant activity. Antioxidants 9 (5):428. doi: 10.3390/antiox9050428.
  • Sneharani, A. H. 2019. Curcumin–sunflower protein nanoparticles—A potential antiinflammatory agent. Journal of Food Biochemistry 43 (8):e12909. doi: 10.1111/jfbc.12909.
  • Steiner, B. M., V. Shukla, D. J. McClements, Y. O. Li, M. Sancho-Madriz, and G. Davidov-Pardo. 2019. Encapsulation of lutein in nanoemulsions stabilized by resveratrol and Maillard conjugates. Journal of Food Science 84 (9):2421–31. doi: 10.1111/1750-3841.14751.
  • Stevanovic, Z. D. 2020. Natural macromolecules as carriers for essential oils: From extraction to biomedical application. Frontiers in Bioengineering and Biotechnology 8:563. doi: 10.3389/fbioe.2020.00563.
  • Teixeira, A. S., A. S. Navarro, A. D. Molina-García, M. Martino, and L. Deladino. 2015. Corn starch systems as carrier for yerba mate (Ilex paraguariensis) antioxidants: Effect of mineral addition. Food and Bioproducts Processing 94:39–49. doi: 10.1016/j.fbp.2015.01.002.
  • Tomadoni, B., C. Capello, G. A. Valencia, and T. J. Gutiérrez. 2020. Self-assembled proteins for food applications: A review. Trends in Food Science & Technology 101:1–16. doi: 10.1016/j.tifs.2020.04.015.
  • Toro-Uribe, S., L. J. López-Giraldo, and E. A. Decker. 2018. Relationship between the physiochemical properties of cocoa procyanidins and their ability to inhibit lipid oxidation in liposomes. Journal of Agricultural and Food Chemistry 66 (17):4490–502. doi: 10.1021/acs.jafc.8b01074.
  • Toro-Uribe, S., E. Ibáñez, E. A. Decker, D. J. McClements, R. Zhang, L. J. López-Giraldo, and M. Herrero. 2018. Design, fabrication, characterization, and in vitro digestion of alkaloid‑, catechin‑, and cocoa extract-loaded liposomes. Journal of Agricultural and Food Chemistry 66 (45):12051–65. doi: 10.1021/acs.jafc.8b04735.
  • Tripodo, G., and D. Mandracchia. 2019. Inulin as a multifaceted (active)substance and its chemical functionalization: From plant extraction to applications in pharmacy, cosmetics and food. European Journal of Pharmaceutics and Biopharmaceutics : official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V 141:21–36. doi: 10.1016/j.ejpb.2019.05.011.
  • Ubeyitogullari, A., and O. N. Ciftci. 2020. Fabrication of bioaerogels from camelina seed mucilage for food applications. Food Hydrocolloids. 102:105597– doi: 10.1016/j.foodhyd.2019.105597.
  • Usach, I., A. Alaimo, J. Fernández, A. Ambrosini, S. Mocini, L. Ochiuz, and J.-E. Peris. 2021. Magnolol and honokiol: Two natural compounds with similar chemical structure but different physicochemical and stability properties. Pharmaceutics 13 (2):224. doi: 10.3390/pharmaceutics13020224.
  • Vu, H. T. H., S. M. Hook, S. D. Siqueira, A. Müllertz, T. Rades, and A. McDowell. 2018. Are phytosomes a superior nanodelivery system for the antioxidant rutin? International Journal of Pharmaceutics 548 (1):82–91. doi: 10.1016/j.ijpharm.2018.06.042.
  • Walia, N., and L. Chen. 2020. Pea protein based vitamin D nanoemulsions: Fabrication, stability and in vitro study using Caco-2 cells. Food Chemistry 305:125475– doi: 10.1016/j.foodchem.2019.125475.
  • Wang, Y., and X. Wang. 2015. Binding, stability, and antioxidant activity of quercetin with soy protein isolate particles. Food Chemistry 188:24–9. doi: 10.1016/j.foodchem.2015.04.127.
  • Wang, C., T. Chang, D. Zhang, C. Ma, S. Chen, and H. Li. 2020. Preparation and characterization of potato protein-based microcapsules with an emphasis on the mechanism of interaction among the main components. Journal of the Science of Food and Agriculture 100 (7):2866–72. doi: 10.1002/jsfa.10277.
  • Wattanathorn, J., N. Palachai, W. Thukham-Mee, and S. Muchimapura. 2020. Memory-enhancing effect of phytosome containing the combined extract of mulberry fruit and ginger in an animal model of ischemic stroke with metabolic syndrome. Oxidative Medicine and Cellular Longevity 2020:3096826. doi: 10.1155/2020/3096826.
  • Winuprasith, T., P. Khomein, W. Mitbumrung, M. Suphantharika, A. Nitithamyong, and D. J. McClements. 2018. Encapsulation of vitamin D3 in pickering emulsions stabilized by nanofibrillated mangosteen cellulose: Impact on in vitro digestion and bioaccessibility. Food Hydrocolloids. 83:153–64. doi: 10.1016/j.foodhyd.2018.04.047.
  • Xia, S., C. Tan, Y. Zhang, S. Abbas, B. Feng, X. Zhang, and F. Qin. 2015. Modulating effect of lipid bilayer–carotenoid interactions on the property of liposome encapsulation. Colloids and Surfaces. B, Biointerfaces 128:172–80. doi: 10.1016/j.colsurfb.2015.02.004.
  • Xiao, J., C. Li, and Q. Huang. 2015. Kafirin nanoparticle-stabilized pickering emulsions as oral delivery vehicles: Physicochemical stability and in vitro digestion profile. Journal of Agricultural and Food Chemistry 63 (47):10263–70. doi: 10.1021/acs.jafc.5b04385.
  • Xiong, J., Y. H. Chan, T. Rathinasabapathy, M. H. Grace, S. Komarnytsky, and M. A. Lila. 2020. Enhanced stability of berry pomace polyphenols delivered in protein-polyphenol aggregate particles to an in vitro gastrointestinal digestion model. Food Chemistry 331:127279. doi: 10.1016/j.foodchem.2020.127279.
  • Yan, W., X. Jia, Q. Zhang, H. Chen, Q. Zhu, and L. Yin. 2021. Interpenetrating polymer network hydrogels of soy protein isolate and sugar beet pectin as a potential carrier for probiotics. Food Hydrocolloids. 113:106453. doi: 10.1016/j.foodhyd.2020.106453.
  • Yan, W., B. Zhang, M. P. Yadav, L. Feng, J. Yan, X. Jia, and L. Yin. 2020. Corn fiber gum-soybean protein isolate double network hydrogel as oral delivery vehicles for thermosensitive bioactive compounds. Food Hydrocolloids. 107:105865– doi: 10.1016/j.foodhyd.2020.105865.
  • Yang, Y., H. Xiao, and D. J. McClements. 2017. Impact of lipid phase on the bioavailability of vitamin e in emulsion- based delivery systems: Relative importance of bioaccessibility, absorption, and transformation. Journal of Agricultural and Food Chemistry 65 (19):3946–55. doi: 10.1021/acs.jafc.7b00955.
  • Zang, X., J. Wang, G. Yu, and J. Cheng. 2019. Addition of anionic polysaccharides to improve the stability of rice bran protein hydrolysate-stabilized emulsions. LWT 111:573–81. doi: 10.1016/j.lwt.2019.04.020.
  • Zardini, A. A., M. Mohebbi, R. Farhoosh, and S. Bolurian. 2018. Production and characterization of nanostructured lipid carriers and solid lipid nanoparticles containing lycopene for food fortification. Journal of Food Science and Technology 55 (1):287–98. doi: 10.1007/s13197-017-2937-5.
  • Zavareze, E. D. R., D. H. Kringel, and A. R. G. Dias. 2019. Nano-scale polysaccharide materials in food and agricultural applications. Advances in Food and Nutrition Research 88:85–128. doi: 10.1016/bs.afnr.2019.02.013.
  • Zhang, R., T. Belwal, L. Li, X. Lin, Y. Xu, and Z. Luo. 2020. Recent advances in polysaccharides stabilized emulsions for encapsulation and delivery of bioactive food ingredients: A review. Carbohydrate Polymers 242:116388. doi: 10.1016/j.carbpol.2020.116388.
  • Zhao, Z., M. Lu, Z. Mao, J. Xiao, Q. Huang, X. Lin, and Y. Cao. 2020. Modulation of interfacial phenolic antioxidant distribution in Pickering emulsions via interactions between zein nanoparticles and gallic acid. International Journal of Biological Macromolecules 152:223–33. doi: 10.1016/j.ijbiomac.2020.02.136.
  • Zhong, L., N. Ma, Y. Wu, L. Zhao, G. Ma, F. Pei, and Q. Hu. 2019. Characterization and functional evaluation of oat protein isolate-Pleurotus ostreatus β-glucan conjugates formed via Maillard reaction. Food Hydrocolloids. 87:459–69. doi: 10.1016/j.foodhyd.2018.08.034.
  • Zhou, Y., S. Sun, W. Bei, M. R. Zahi, Q. Yuan, and H. Liang. 2018. Preparation and antimicrobial activity of oregano essential oil Pickering emulsion stabilized by cellulose nanocrystals. International Journal of Biological Macromolecules 112:7–13. doi: 10.1016/j.ijbiomac.2018.01.102.
  • Zhu, F. 2017. Encapsulation and delivery of food ingredients using starch based systems. Food Chemistry 229:542–52. doi: 10.1016/j.foodchem.2017.02.101.
  • Zou, L., B. Zheng, R. Zhang, Z. Zhang, W. Liu, C. Liu, H. Xiao, and D. J. McClements. 2016. Food-grade nanoparticles for encapsulation, protection and delivery of curcumin: Comparison of lipid, protein, and phospholipid nanoparticles under simulated gastrointestinal conditions. RSC Advances 6 (4):3126–36. doi: 10.1039/C5RA22834D.

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