Acinetobacter baumannii subunit vaccines: recent progress and challenges

References

• Aghajani Z, Rasooli I, Mousavi Gargari SL. 2019. Exploitation of two siderophore receptors, BauA and BfnH, for protection against Acinetobacter baumannii infection. APMIS. 127(12):753–763.
   PubMed Web of Science ®Google Scholar
• Ahmad TA, Tawfik DM, Sheweita SA, Haroun M, El-Sayed LH. 2016. Development of immunisation trials against Acinetobacter baumannii. Trials Vaccinol. 5:53–60.
   Google Scholar
• Akbari Z, Rasooli I, Ghaini MH, Chaudhuri S, Farshchi Andisi V, Jahangiri A, Ramezanalizadeh F, Schryvers AB. 2022. BauA and Omp34 surface loops trigger protective antibodies against Acinetobacter baumannii in a murine sepsis model. Int Immunopharmacol. 108:108731.
   PubMed Web of Science ®Google Scholar
• Alipouri S, Rasooli I, Ghaini MH, Jahangiri A, Darvish Alipour Astaneh S, Ramezanalizadeh F. 2022. Immunity induced by valine-glycine repeat protein G imparts his protection of vital body organs against Acinetobacter baumannii. J Genet Eng Biotechnol. 20(1):1–9.
   PubMed Web of Science ®Google Scholar
• Ansari H, Tahmasebi-Birgani M, Bijanzadeh M, Doosti A, Kargar M. 2019. Study of the immunogenicity of outer membrane protein A (ompA) gene from Acinetobacter baumannii as DNA vaccine candidate in vivo. Iran J Basic Med Sci. 22(6):669–675.
   PubMed Web of Science ®Google Scholar
• Badmasti F, Ajdary S, Bouzari S, Fooladi AA, Shahcheraghi F, Siadat SD. 2015. Immunological evaluation of OMV(PagL)+Bap (1-487aa) and AbOmpA (8-346aa)+Bap (1-487aa) as vaccine candidates against Acinetobacter baumannii sepsis infection. Mol Immunol. 67(2 Pt B):552–558.
   PubMed Web of Science ®Google Scholar
• Badmasti F, Siadat S, Bouzari S, Nasiri O, Nemati H, Shahcheraghi F. 2015. Molecular analysis of AbOmpA type-1 as immunogenic target for therapeutic interventions against MDR Acinetobacter baumannii infection. vacres. 2(3):9–18.
   Google Scholar
• Bahey-El-Din M, Mohamed SA, Sheweita SA, Haroun M, Zaghloul TI. 2020. Recombinant N-terminal outer membrane porin (OprF) of Pseudomonas aeruginosa is a promising vaccine candidate against both P. aeruginosa and some strains of Acinetobacter baumannii. Int J Med Microbiol. 310(3):151415.
   PubMed Web of Science ®Google Scholar
• Bazmara H, Rasooli I, Jahangiri A, Sefid F, Astaneh SD, Payandeh Z. 2019. Antigenic properties of iron regulated proteins in Acinetobacter baumannii: an in silico approach. Int J Pept Res Ther. 25(1):205–213.
   Web of Science ®Google Scholar
• Bentancor LV, Camacho-Peiro A, Bozkurt-Guzel C, Pier GB, Maira-Litrán T. 2012. Identification of Ata, a multifunctional trimeric autotransporter of Acinetobacter baumannii. J Bacteriol. 194(15):3950–3960.
   PubMed Web of Science ®Google Scholar
• Bhamidimarri SP, Zahn M, Prajapati JD, Schleberger C, Söderholm S, Hoover J, West J, Kleinekathöfer U, Bumann D, Winterhalter M, et al. 2019. A multidisciplinary approach toward identification of antibiotic scaffolds for Acinetobacter baumannii. Structure. 27(2):268–280.e6.
   PubMed Web of Science ®Google Scholar
• Bolourchi N, Shahcheraghi F, Shirazi AS, Janani A, Bahrami F, Badmasti F. 2019. Immunogenic reactivity of recombinant PKF and AbOmpA proteins as serum resistance factors against sepsis of Acinetobacter baumannii. Microb Pathog. 131:9–14.
   PubMed Web of Science ®Google Scholar
• Centers for Disease Control and Prevention. 2022. COVID-19 U.S. impact on antimicrobial resistance, Special report 2022. Atlanta: U.S. Department of Health and Human Services, CDC; https://www.cdc.gov/drugresistance/covid19.html.
   Google Scholar
• Chaudhuri S, Rasooli I, Oskouei RH, Pishgahi M, Jahangir A, Andisi VF, Schryvers AB. 2022. Hybrid antigens expressing surface loops of BauA from Acinetobacter baumannii are capable of inducing protection against infection. Front Immunol. 13:933445.
   PubMed Web of Science ®Google Scholar
• Chen W. 2015. Current advances and challenges in the development of Acinetobacter vaccines. Hum Vaccin Immunother. 11(10):2495–2500.
   PubMed Web of Science ®Google Scholar
• Chiang M-H, Sung W-C, Lien S-P, Chen Y-Z, Lo AF-y, Huang J-H, Kuo S-C, Chong P. 2015. Identification of novel vaccine candidates against Acinetobacter baumannii using reverse vaccinology. Hum Vaccin Immunother. 11(4):1065–1073.
   PubMed Web of Science ®Google Scholar
• Clark RB. 1996. Imipenem resistance among Acinetobacter baumannii: association with reduced expression of a 33–36 kDa outer membrane protein. J Antimicrob Chemother. 38(2):245–251.
   PubMed Web of Science ®Google Scholar
• Dijkshoorn L, Nemec A, Seifert H. 2007. An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat Rev Microbiol. 5(12):939–951.
   PubMed Web of Science ®Google Scholar
• Du X, Xue J, Jiang M, Lin S, Huang Y, Deng K, Shu L, Xu H, Li Z, Yao J, et al. 2021. Nov 10] A multi-epitope peptide rOmp22 encapsulated in chitosan-PLGA nanoparticles as vaccine candidate against Acinetobacter baumannii infection. Int J Nanomedicine. 16:1819–1836.
   PubMed Web of Science ®Google Scholar
• Erami AN, Rasooli I, Jahangiri A, Astaneh SD. 2021. Anti-Omp34 antibodies protect against Acinetobacter baumannii in a murine sepsis model. Microb Pathog. 161(Pt B):105291.
   PubMedGoogle Scholar
• Facciolà A, Visalli G, Laganà A, Di Pietro A. 2022. An overview of vaccine adjuvants: current evidence and future perspectives. Vaccines. 10(5):819.
   Web of Science ®Google Scholar
• Fajardo Bonin R, Chapeaurouge A, Perales J, da Silva JG, do Nascimento HJ, D’Alincourt Carvalho Assef AP, Moreno Senna JP. 2014. Identification of immunogenic proteins of the bacterium Acinetobacter baumannii using a proteomic approach. Proteomics Clin Appl. 8(11–12):916–923.
   PubMed Web of Science ®Google Scholar
• Fereshteh S, Abdoli S, Shahcheraghi F, Ajdary S, Nazari M, Badmasti F. 2020. New putative vaccine candidates against Acinetobacter baumannii using the reverse vaccinology method. Microb Pathog. 143:104114.
   PubMed Web of Science ®Google Scholar
• Fereshteh S, Goodarzi NN, Sepehr A, Shafiei M, Ajdary S, Badmasti F. 2022. In silico analyses of extracellular proteins of Acinetobacter baumannii as immunogenic candidates. Iran J Pharm Res. 21(1):e126559.
   PubMed Web of Science ®Google Scholar
• Garg N, Singh R, Shukla G, Capalash N, Sharma P. 2016. Immunoprotective potential of in silico predicted Acinetobacter baumannii outer membrane nuclease, NucAB. Int J Med Microbiol. 306(1):1–9.
   PubMed Web of Science ®Google Scholar
• Girija A, Shoba G, Priyadharsini JV. 2021. Accessing the t-cell and b-cell immuno-dominant peptides from A. baumannii biofilm associated protein (bap) as vaccine candidates: a computational approach. Int J Pept Res Ther. 27(1):37–45.:
   Web of Science ®Google Scholar
• Golestani F, Malekan M, Rasooli I, Jahangiri A, Ramezanalizadeh F, Chaudhuri S, Farshchi Andisi V, Schryvers AB. 2022. Immunogenicity of loop 3 of omp34 from A. baumannii in loopless c-lobe of TbpB of N. meningitidis. Int Immunopharmacol. 110:109013.
   PubMed Web of Science ®Google Scholar
• Guo SJ, Ren S, Xie YE. 2018. Evaluation of the protective efficacy of a fused Ompk/Omp22 protein vaccine candidate against Acinetobacter baumannii infection in mice. Biomed Environ Sci. 31(2):155–158.
   PubMed Web of Science ®Google Scholar
• Hashemzehi R, Doosti A, Kargar M, Jaafarinia M. 2018. Cloning and expression of nlpA gene as DNA vaccine candidate against Acinetobacter baumannii. Mol Biol Rep. 45(4):395–401.
   PubMed Web of Science ®Google Scholar
• Hatefi Oskuei R, Darvish Alipour Astaneh S, Rasooli I. 2021. A conserved region of Acinetobacter trimeric autotransporter adhesion, Ata, provokes suppression of Acinetobacter baumannii virulence. Arch Microbiol. 203(6):3483–3493.
   PubMed Web of Science ®Google Scholar
• Huang W, Wang S, Yao Y, Xia Y, Yang X, Li K, Sun P, Liu C, Sun W, Bai H, et al. 2016. Employing Escherichia coli-derived outer membrane vesicles as an antigen delivery platform elicits protective immunity against Acinetobacter baumannii infection. Sci Rep. 6(37242):37242.
   PubMedGoogle Scholar
• Huang W, Wang S, Yao Y, Xia Y, Yang X, Long Q, Sun W, Liu C, Li Y, Ma Y, et al. 2015. OmpW is a potential target for eliciting protective immunity against Acinetobacter baumannii infections. Vaccine. 33(36):4479–4485.
   PubMed Web of Science ®Google Scholar
• Huang W, Yao Y, Long Q, Yang X, Sun W, Liu C, Jin X, Li Y, Chu X, Chen B, et al. 2014. Immunisation against multidrug-resistant Acinetobacter baumannii effectively protects mice in both pneumonia and sepsis models. PLoS One. 9(6):e100727.
   PubMed Web of Science ®Google Scholar
• Huang W, Yao Y, Wang S, Xia Y, Yang X, Long Q, Sun W, Liu C, Li Y, Chu X, et al. 2016. Immunisation with a 22-kDa outer membrane protein elicits protective immunity to multidrug-resistant Acinetobacter baumannii. Sci Rep. 6(20724):20724.
   PubMedGoogle Scholar
• Jahangiri A, Rasooli I, Owlia P, Fooladi AA, Salimian J. 2018. An integrative in silico approach to the structure of Omp33-36 in Acinetobacter baumannii. Comput Biol Chem. 72:77–86.
   PubMed Web of Science ®Google Scholar
• Jahangiri A, Rasooli I, Owlia P, Fooladi AAI, Salimian J. 2018. Highly conserved exposed immunogenic peptides of Omp34 against Acinetobacter baumannii: an innovative approach. J Microbiol Methods. 144:79–85.
   PubMed Web of Science ®Google Scholar
• Khalid K, Andleeb S. 2022. In-silico design and assessment of OprD-based multi-epitope vaccine against Acinetobacter baumannii. bioRxiv. Available from 10.1101/2022.05.25.493433v1.
   Google Scholar
• Khalid K, Irum S, Ullah SR, Andleeb S. 2022. In-silico vaccine design based on a novel vaccine candidate against infections caused by Acinetobacter baumannii. Int J Pept Res Ther. 28(1):16.
   PubMed Web of Science ®Google Scholar
• Lei L, Yang F, Zou J, Jing H, Zhang J, Xu W, Zou Q, Zhang J, Wang X. 2019. DNA vaccine encoding OmpA and Pal from Acinetobacter baumannii efficiently protects mice against pulmonary infection. Mol Biol Rep. 46(5):5397–5408.
   PubMed Web of Science ®Google Scholar
• Li H, Tan H, Hu Y, Pan P, Su X, Hu C. 2017. Small protein A and phospholipase D immunisation serves a protective role in a mouse pneumonia model of Acinetobacter baumannii infection. Mol Med Rep. 16(2):1071–1078.
   PubMed Web of Science ®Google Scholar
• Lin L, Tan B, Pantapalangkoor P, Ho T, Hujer AM, Taracila MA, Bonomo RA, Spellberg B. 2013. Acinetobacter baumannii rOmpA vaccine dose alters immune polarisation and immunodominant epitopes. Vaccine. 31(2):313–318.
   PubMed Web of Science ®Google Scholar
• Luo G, Lin L, Ibrahim AS, Baquir B, Pantapalangkoor P, Bonomo RA, Doi Y, Adams MD, Russo TA, Spellberg B. 2012. Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infection. PLoS One. 7(1):e29446.
   PubMed Web of Science ®Google Scholar
• Mahapatra SR, Dey J, Jaiswal A, Roy R, Misra N, Suar M. 2022. Immunoinformatics-guided designing of epitope-based subunit vaccine from pilus assembly protein of Acinetobacter baumannii bacteria. J Immunol Methods. 508:113325.
   PubMed Web of Science ®Google Scholar
• Mahmoudi Z, Rasooli I, Jahangiri A, Darvish Alipour Astaneh S. 2020. Prevention of nosocomial Acinetobacter baumannii infections with a conserved immunogenic fimbrial protein. APMIS. 128(7):476–483.
   PubMed Web of Science ®Google Scholar
• Mat Rahim N, Lee H, Strych U, AbuBakar S. 2021. Facing the challenges of multidrug-resistant Acinetobacter baumannii: progress and prospects in the vaccine development. Hum Vaccin Immunother. 17(10):3784–3794.
   PubMed Web of Science ®Google Scholar
• McConnell MJ, Pachón J. 2011. Expression, purification, and refolding of biologically active Acinetobacter baumannii OmpA from Escherichia coli inclusion bodies. Protein Expr Purif. 77(1):98–103.
   PubMed Web of Science ®Google Scholar
• Mehdinejadiani K, Bandehpour M, Hashemi A, Ranjbar MM, Taheri S, Jalali SA, Mosaffa N. 2019. In silico design and evaluation of acinetobacter baumannii outer membrane protein A (OmpA) antigenic peptides as vaccine candidate in immunised mice. Iran J Allergy Asthma Immunol. 18(6):655–663.
   PubMed Web of Science ®Google Scholar
• Mehdinejadiani K, Hashemi A, Bandehpour M, Rahmani H, Ranjbar MM, Yardel V, Jalali SA, Mosaffa N. 2021. Evaluation of the new outer membrane protein A epitope-based vaccines for mice model of Acinetobacter baumannii associated pneumonia and sepsis infection. Iran J Allergy Asthma Immunol. 20(5):537–549.
   PubMed Web of Science ®Google Scholar
• Meskini M, Goodarzi NN, Fereshteh S, Bolourchi N, Mirzaie A, Badmasti F. 2022. A bioinformatics approach to introduce novel multi-epitope vaccines against Acinetobacter baumannii retrieved from immunogenic extracellular loops of outer membrane proteins. Inform Med Unlocked. 31:100989.
   Google Scholar
• Moriel DG, Beatson SA, Wurpel DJ, Lipman J, Nimmo GR, Paterson DL, Schembri MA. 2013. Identification of novel vaccine candidates against multidrug-resistant Acinetobacter baumannii. PLoS One. 8(10):e77631.
   PubMed Web of Science ®Google Scholar
• Ni Z, Chen Y, Ong E, He Y. 2017. Antibiotic resistance determinant-focused Acinetobacter baumannii vaccine designed using reverse vaccinology. IJMS. 18(2):458.
   Google Scholar
• Pan P, Zhu F, Ma S, Rao M, Zhang P, Peng W, Cui Y, Yang H, Tan C, Chen J. 2022. Immunoinformatics approaches for developing multi-epitope subunit vaccines to combat Acinetobacter baumannii. Res Sq. https://europepmc.org/article/ppr/ppr446294.
   PubMedGoogle Scholar
• Pazoki M, Astaneh SD, Ramezanalizadeh F, Jahangiri A, Rasooli I. 2021. Immunoprotectivity of valine–glycine repeat protein G, a potent mediator of pathogenicity, against Acinetobacter baumannii. Mol Immunol. 135:276–284.
   PubMed Web of Science ®Google Scholar
• Peleg AY, Seifert H, Paterson DL. 2008. Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev. 21(3):538–582.
   PubMed Web of Science ®Google Scholar
• Piri-Gharaghie T, Doosti A, Mirzaei SA. 2022. Identification of antigenic properties of Acinetobacter baumannii proteins as novel putative vaccine candidates using reverse vaccinology approach. Appl Biochem Biotechnol. 194(10):4892–4914.
   PubMed Web of Science ®Google Scholar
• Qamsari MM, Rasooli I, Astaneh SDA. 2020. Identification and immunogenic properties of recombinant ZnuD protein loops of Acinetobacter baumannii. Inform Med Unlocked. 19:100342.
   Google Scholar
• Qamsari MM, Rasooli I, Chaudhuri S, Astaneh SD, Schryvers AB. 2020. Hybrid antigens expressing surface loops of ZnuD from Acinetobacter baumannii is capable of inducing protection against infection. Front Immunol. 11:158.
   PubMed Web of Science ®Google Scholar
• Ramezanalizadeh F, Owlia P, Rasooli I. 2020. Type I pili, CsuA/B and FimA induce a protective immune response against Acinetobacter baumannii. Vaccine. 38(34):5436–5446.
   PubMed Web of Science ®Google Scholar
• Ramezanalizadeh F, Rasooli I, Owlia P. 2021. Protective response against Acinetobacter baumannii with ferric iron receptors HemTR-BauA in a murine sepsis model. Future Microbiol. 16(3):159–173.
   PubMed Web of Science ®Google Scholar
• Raoufi Z, Abdollahi S, Armand R. 2022. DcaP porin and its epitope-based subunit promise effective vaccines against Acinetobacter baumannii; in-silico and in-vivo approaches. Microb Pathog. 162:105346.
   PubMed Web of Science ®Google Scholar
• Rasooli I, Abdolhamidi R, Jahangiri A, Darvish Alipour Astaneh S. 2020. Outer membrane protein, Oma87 prevents Acinetobacter baumannii infection. Int J Pept Res Ther. 26(4):2653–2660.
   PubMed Web of Science ®Google Scholar
• Ren S, Guan L, Dong Y, Wang C, Feng L, Xie Y. 2019. Design and evaluation of a multi-epitope assembly peptide vaccine against Acinetobacter baumannii infection in mice. Swiss Med Wkly. 149(2324):w20052.
   PubMedGoogle Scholar
• Rumbo C, Tomás M, Fernández Moreira E, Soares NC, Carvajal M, Santillana E, Beceiro A, Romero A, Bou G. 2014. The Acinetobacter baumannii Omp33-36 porin is a virulence factor that induces apoptosis and modulates autophagy in human cells. Infect Immun. 82(11):4666–4680.
   PubMed Web of Science ®Google Scholar
• Scheaffer SM, Lee D, Whitener B, Ying B, Wu K, Liang C-Y, Jani H, Martin P, Amato NJ, Avena LE, et al. 2023. Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in mice. Nat Med. 29(1):247–257.
   PubMed Web of Science ®Google Scholar
• Shahid F, Zaheer T, Ashraf ST, Shehroz M, Anwer F, Naz A, Ali A. 2021. Chimeric vaccine designs against Acinetobacter baumannii using pan-genome and reverse vaccinology approaches. Sci Rep. 11(1):13213.
   PubMed Web of Science ®Google Scholar
• Siegrist CA. 2013. Vaccine immunology. In: Plotkin SA, Orenstein WA, Offit PA, editors. Vaccines. 6th ed. London: W. B. Saunders; p. 14–32.
   Google Scholar
• Singh R, Capalash N, Sharma P. 2017. Immunoprotective potential of BamA, the outer membrane protein assembly factor, against MDR Acinetobacter baumannii. Sci Rep. 7(1):12411.
   PubMed Web of Science ®Google Scholar
• Singh R, Capalash N, Sharma P. 2022. Vaccine development to control the rising scourge of antibiotic-resistant Acinetobacter baumannii: a systematic review. 3 Biotech. 12(3):14–85.
   PubMedGoogle Scholar
• Singh R, Garg N, Shukla G, Capalash N, Sharma P. 2016. Immunoprotective efficacy of Acinetobacter baumannii outer membrane protein, FilF, predicted in silico as a potential vaccine candidate. Front Microbiol. 7:158.
   PubMed Web of Science ®Google Scholar
• Skerniškytė J, Karazijaitė E, Deschamps J, Krasauskas R, Armalytė J, Briandet R, et al. 2019. Blp1 protein shows virulence-associated features and elicits protective immunity to Acinetobacter baumannii infection. BMC Microbiol. 19(259):1–12.
   PubMedGoogle Scholar
• Smani Y, Dominguez-Herrera J, Pachón J. 2013. Association of the outer membrane protein Omp33 with fitness and virulence of Acinetobacter baumannii. J Infect Dis. 208(10):1561–1570.
   PubMed Web of Science ®Google Scholar
• Soltani Shirazi A, Azizi O, Bolourchi N, Aghamohammad S, Badmasti F. 2017. Comparative in silico analyses of proteins involved in serum resistance as promising vaccine candidates against Acinetobacter baumannii. vacres. 4(3):64–71.
   Google Scholar
• Sun P, Li X, Pan C, Liu Z, Wu J, Wang H, Zhu L. 2022. A short peptide of autotransporter Ata is a promising protective antigen for vaccination against Acinetobacter baumannii. Front Immunol. 13:884555.
   PubMed Web of Science ®Google Scholar
• Tohidinia M, Moshtaghioun SM, Sefid F, Falahati A. 2020. Functional exposed amino acids of CarO analysis as a potential vaccine candidate in Acinetobacter baumannii. Int J Pept Res Ther. 26(3):1185–1197.
   Web of Science ®Google Scholar
• Touhidinia M, Sefid F, Bidakhavidi M. 2021. Design of a multi-epitope vaccine against Acinetobacter baumannii using immunoinformatics approach. Int J Pept Res Ther. 27(4):2417–2437.
   PubMed Web of Science ®Google Scholar
• Ud-Din M, Albutti A, Ullah A, Ismail S, Ahmad S, Naz A, Khurram M, Haq M u, Afsheen Z, Bakri YE, et al. 2022. Vaccinomics to design a multi-epitopes vaccine for Acinetobacter baumannii. IJERPH. 19(9):5568.
   Web of Science ®Google Scholar
• Vieira de Araujo AE, Conde LV, da Silva Junior HC, de Almeida Machado L, Lara FA, Chapeaurouge A, Pauer H, Pires Hardoim CC, Martha Antunes LC, D’Alincourt Carvalho-Assef AP, et al. 2021. Cross-reactivity and immunotherapeutic potential of BamA recombinant protein from Acinetobacter baumannii. Microbes Infect. 23(4-5):104801.
   PubMed Web of Science ®Google Scholar
• Vrancianu CO, Gheorghe I, Czobor IB, Chifiriuc MC. 2020. Antibiotic resistance profiles, molecular mechanisms and innovative treatment strategies of Acinetobacter baumannii. Microorganisms. 8(6):935.
   PubMed Web of Science ®Google Scholar
• World Health Organization 2022. Bacterial vaccines in clinical and preclinical development: an overview and analysis. Geneve: World Health Organization; p. 92.
   Google Scholar
• World Health Organization. 2017. WHO publishes a list of bacteria for which new antibiotics are urgently needed. Geneve: World Health Organization. https://www.who.int/news-room/detail/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed.
   Google Scholar
• Yang AQ, Yang HY, Guo SJ, Xie YE. 2019. MF59 adjuvant enhances the immunogenicity and protective immunity of the Ompk/o]Omp22 fusion protein from Acineterbacter baumannii through intratracheal inoculation in mice. Scand J Immunol. 90(1):e12769.
   PubMed Web of Science ®Google Scholar
• Zadeh Hosseingholi E, Rasooli I, Mousavi Gargari SL. 2014. In silico analysis of Acinetobacter baumannii phospholipase D as a subunit vaccine candidate. Acta Biotheor. 62(4):455–478.
   PubMed Web of Science ®Google Scholar
• Zhu T, Lei Z, Qu S, Zhao F, Yan L, Chen M, Zhou XW, Qu D, Zhao Y. 2022. Comparison of the outer membrane proteomes between clinical carbapenem-resistant and -susceptible Acinetobacter baumannii. Lett Appl Microbiol. 74(6):873–882.
   PubMed Web of Science ®Google Scholar