Dose-Response Features of Neuroprotective Agents: An Integrative Summary

APPENDIX REFERENCES

• Abe K., Chida N., Nishiyama N., Saito H. Spermine promotes the survival of primary cultured brain neurons. Brain Res. 1993; 605: 322–326
   PubMed Web of Science ®Google Scholar
• Abraham I. M., Harkany T., Horvath K. M., Luiten P. G.M. Action of glucocorticoids on survival on nerve cells: Promoting neurodegeneration or neuroprotection?. J. Neuroendocrinology 2001; 13: 749–760
   PubMed Web of Science ®Google Scholar
• Abraham I., Harkany T., Horvath K. M., Veenema A. H., Penke B., Nyakas C., Luiten P. G.M. Chronic corticosterone administration dose-dependently modulates Aβ(1 − 42)-and NMDA-induced neurodegeneration in rat magnocellular nucleus basalis. J. Neuroendocrinology 2000; 12: 486–494
   PubMed Web of Science ®Google Scholar
• Arias E., Gallego-Sandin S., Villarroya M., Garcia A. G., Lopez M. G. Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: Role of nictoinic receptors. J. Pharmacol. Exper. Therap. 2005; 315: 1346–1353
   PubMed Web of Science ®Google Scholar
• Bai F., Li X., Blay M., Lindstrom T., Skolnick P. Intra-and interstrain differences in models of “behavioral despair”. Pharmacol. Biochem. Behav. 2001; 70: 187–192
   PubMed Web of Science ®Google Scholar
• Bambrick L. L., Yarowsky P. J., Krueger B. K. Glutamate as a hippocampal neuron survival factor: An inherited defect in the trisomy 16 mouse. Proc. Natl. Acad. Sci. USA 1995; 92: 9692–9696
   PubMed Web of Science ®Google Scholar
• Bocker-Meffert S., Rosenstiel P., Rohl C., Warneke N., Held-Feindt J., Sievers J., Lucius R. Erythropoietin and BEGF promote neural outgrowth from retinal explants in postnatal rats. Invest. Opththalmol. Vis. Sci. 2002; 43: 2021–2026
   PubMed Web of Science ®Google Scholar
• Borges V. C., Rocha J. B.T., Nogueira C. W. Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na+, K+-ATPase activity in rats. Toxicology, 2005; 215: 191–197
   PubMed Web of Science ®Google Scholar
• Boyd J. G., Gordon T. A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor. Eur. J. Neurosci. 2002; 15: 613–626
   PubMed Web of Science ®Google Scholar
• Brenneman D. E., Gozes I. A femtomolar-acting neuroprotective peptide. J. Clin. Invest., 1996; 97(10)2299–2307
   PubMed Web of Science ®Google Scholar
• Brenneman D. E., Hauser J., Neale E., Rubinraut S., Fridkin M., Davidson A., Gozes I. Activity-dependent neurotrophic factor: Structure-activity relationships of femtomolar-acting peptides. J. Pharmacol. Exper. Therap. 1998; 285: 619–627
   PubMed Web of Science ®Google Scholar
• Brenneman D. E., Forsythe I. D., Nicol T., Nelson P. G. N-methyl-D-aspartate receptors influence neuronal survival in developing spinal cord cultures. Dev. Brain Res. 1990a; 51: 63–68
   PubMedGoogle Scholar
• Brenneman D. E., Yu C., Nelson P. G. Multi-determinate regulation of neuronal survival: neuropeptides, excitatory amino acids and bioelectric activity. Int. J. Dev. Neurosci. 1990b; 8: 371–378
   PubMed Web of Science ®Google Scholar
• Brewer L. D., Thibault V., Chen K.-C., Langub M. C., Landfield P. W., Porter N. M. Vitamin D hormone confers neutroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons. J. Neurosci. 2001; 21: 98–108
   PubMed Web of Science ®Google Scholar
• Brodie C., Goldreich N. Interleukin-4 modulates the proliferation and differentiation of glial cells. J. Neuroimmunology 1994; 55: 91–97
   PubMed Web of Science ®Google Scholar
• Butterweck V., Petereit F., Winterhoff H., Nahrstedt A. Solubilized hypericin and pseudohypericin from Hypericum perforatum exert antidepressant activity in the forced swimming test. Planta Medica 1998; 64: 291–294
   PubMed Web of Science ®Google Scholar
• Butterweck V., Wall A., Lieflander-Wulf U., Winterhoff H., Nahrstedt A. Effects of the total extract and fractions of Hypericum perforatum in animal assays for antidepressant activity. Pharmacopsychiat 1997; 30: 117–124
   PubMed Web of Science ®Google Scholar
• Castagné V., Barnéoud P., Clarke P. G.H. Protection of axotomized ganglion cells by salicylic acid. Brain Res., 1999; 840: 162–166
   PubMed Web of Science ®Google Scholar
• Chaube R., Joy K. P. Estrogen regulation of in vitro brain tyrosine hydroxylase activity in the catfish Heteropneustes fossilis: interactions with cAMP-protein kinase A and protein kinase C systems in enzyme activation. Gen. Comp. Endocrinol., 2005; 141: 116–125
   PubMed Web of Science ®Google Scholar
• Chu P.-J., Shirahata A., Samejima K., Saito H., Abe K. Structural requirement for neutrophic activity of spermine in cultured rat hippocampal neurons. Jpn. J. Pharmacol. 1995; 67: 173–17
   PubMedGoogle Scholar
• Chung K. C., Park J. H., Kim C. H., Lee H. W., Sato N., Uchiyama Y., Ahn Y. S. Novel biphasic effect of pyrrolidine dithiocarbamate on neuronal cell viability is mediated by the differential regulation of intracellular zinc and copper ion levels, NF-kB, and MAP kinases. J. Neurosci. Res. 2000; 59: 117–125
   PubMed Web of Science ®Google Scholar
• Conti A. M., Fischer S. J., Windebank A. J. Inhibition of axonal growth from sensory neurons by excess nerve growth factor. Ann. Neurol. 1997; 42: 838–84
   PubMed Web of Science ®Google Scholar
• Cookson M. R. Studies of activation and toxicity in cultured astrocytes. Doctoral Dissertation, University of Salford, UK. 1995
   Google Scholar
• Cookson M. R., Mead C., Austwick S. M., Pentreath V. W. Use of the MTT assay for estimating toxicity in primary astocyte and C6 glioma cell cultures. Toxic. In Vitro 1995; 9: 39–48
   PubMed Web of Science ®Google Scholar
• Costantini L. C., Isacson O. Immunophilin ligands and GDNF enhance neurite branching or elongation from developing dopamine neurons in culture. Exper. Neurology 2000; 164: 60–70
   PubMed Web of Science ®Google Scholar
• De-Oliveira R. W., Guimaraes F. S. Anxiolytic effect of methylene blue microinjected into the dorsal periaqueductal gray matter. Braz. J. Med. Biol. Res. 1999; 32: 1529–1532
   PubMed Web of Science ®Google Scholar
• Devito W. J., Avakian C., Stone S., Okulicz W. C. Prolactin-stimulated mitogenesis of cultured astrocytes is mediated by a protein kinase C-dependent mechanism. J. Neurochem. 1993; 60: 835–842
   Web of Science ®Google Scholar
• Doige C. A., Yu Z., Sharom F. J. The effects of lipids and detergents on ATPase active P-glycoprotein. Biochim. Biophys. Acta. 1993; 1146: 65–72
   PubMed Web of Science ®Google Scholar
• Eroglu L., Caglayan B. Anxiolytic and antidepressant properties of methylene blue in animal models. Pharmacol. Res. 1997; 36: 381–385
   PubMed Web of Science ®Google Scholar
• Favit A., Sortino M. A., Aleppo G., Scapagnini U., Canonico P. L. Protection by dihydroergocryptine of glutamate-induced neurotoxicity. Pharmacol. Toxicol. 1993; 73: 224–228
   PubMedGoogle Scholar
• Flood J. F., Morley J. E., La Reginna M. Age-related changes in the pharmacological improvement of retention in senescence accelerated mouse (SAM). Neurobiol. Aging 1993; 14: 159–166
   PubMed Web of Science ®Google Scholar
• Flood J. F., Smith G. E., Roberts E. Dehydroepiandrosterone and its sulfate enhance memory retention in mice. Brain Res. 1988; 447: 269–278
   PubMed Web of Science ®Google Scholar
• Flood J. F., Hernandez E. N., Morley J. E. Modulation of memory processing by neuropeptide Y. Brain Res. 1987a; 421: 280–290
   PubMed Web of Science ®Google Scholar
• Flood J. F., Smith G. E., Morley J. E. Modulation of memory processing by cholecystokinin: Dependence on the vagus nerve. Science 1987b; 236: 832–834
   PubMed Web of Science ®Google Scholar
• Frizzo M. E., Dall'Onder L. P., Dalcin K. B., Souza D. O. Riluzole enhances glutamate uptake in rat astrocyte cultures. Cell. Mol. Neurobiol., 2004; 24(1)123–128
   PubMed Web of Science ®Google Scholar
• Furukawa K., Estus S., Fu W., Mark R. J., Mattson M. P. Neuroprotective action of cycloheximide involves induction of Bcl-2 and antioxidant pathways. J. Cell Biol. 1997; 136(5)1137–1149
   PubMed Web of Science ®Google Scholar
• Gago N., El-Etr M.m, Sananès N., Cadepond F., Samuel D., Avellana-Adalid V., Baron-Van Evercooren A., Schumacher M. 2α, 5α-Tetrahydroprogesterone (Allopregnanolone) and γ-aminobutyric acid: Autocrine/paracrine interactions in the control of neonatal PSA-NCAM+ progenitor proliferation. J. Neurosci. Res. 2004; 78: 770–783
   PubMed Web of Science ®Google Scholar
• Gandolfo P., Patte C., Leprince J., Do Rego J.-L., Mensah-Nyagan A. G., Vaudry H., Tonon M.-C. The triakontatetraneuropeptide (TTN) stimulates thymidine incorporation in rat astrocytes through peripheral-type benzodiazepine receptors. J. Neurochem 2000; 75: 701–707
   PubMed Web of Science ®Google Scholar
• Gille G., Rausch W.-D., Hung S.-T., Moldzio R., Ngyuen A., Janetzky B., Engfer A., Reichmann H. Protection of dopaminergic neurons in primary culture by lisuride. Neural Transm. 2002; 109: 157–169
   PubMed Web of Science ®Google Scholar
• Glowa J. R., Dews P. B. Behavioral toxicology of volatile organic solvents. IV. Comparisons of the rate-decreasing effects of acetone, ethyl acetate, methyl ethyl ketone, toluene, and carbon disulfide on schedule-controlled behavior of mice. J. Amer. Coll. Toxicol. 1987; 6: 461–469
   Google Scholar
• Gold P. E., van Buskirk R. B. Post-training brain norepinephrine concentrations: correlation with retention performance of avoidance training and with peripheral epinephrine modulation of memory processing. Behav. Biol. 1978; 23: 509–520
   PubMedGoogle Scholar
• Gold P. E., van Buskirk R. B. Enhancement and impairment of memory processes with post-trial injection of adrenocorticotrophic hormone. Behav. Biol. 1976; 16: 387–400
   PubMedGoogle Scholar
• Gold P. E., van Buskirk R. B. Facilitation of time-dependent memory processes with post-trial epinephrine injections. Behav. Biol. 1975; 13: 145–153
   PubMedGoogle Scholar
• Graf M., Kantor S., Anheuer Z. E., Modos E. A., Bagdy G. M-CPP-induced self grooming is mediated by 5-HTT2C receptors. Behav. Brain Res. 2003; 142: 175–179
   PubMed Web of Science ®Google Scholar
• Guimaraes F. S., Deaguiar J. C., Delbel E. A., Ballejo G. Anxiolytic effect of nitric-oxide synthase inhibitors microinjected into the dorsal central grey. NeuroReport 1994; 5: 1929–1932
   PubMed Web of Science ®Google Scholar
• Gursoy E., Cardounel A., Kalimi M. The environmental estrogenic compound bisphenol A exerts estrogenic erects on mouse hippocampal (HT-22) cells: neuroprotection against glutamate and amyloid beta protein toxicity. Neurochem. Internl. 2001; 38: 181–186
   PubMed Web of Science ®Google Scholar
• Hagan J. J., Bohus B., de Wied D. Post-training vasopressin injections may facilitate or delay shuttle-box avoidance extinction. Behav. Neural Biol. 1982; 36: 211–228
   PubMedGoogle Scholar
• Hayashi T., Tasao L.-I., Su T.-P. Antiapoptotic and cytotoxic properties of delta opioid peptide [D-Ala2, D-Leu5]enkephalin in PC12 cells. Synapse 2002; 43: 86–94
   PubMed Web of Science ®Google Scholar
• Henckaerts E., Langer J. C., Orenstein J., Snoeck H. W. The positive regulatory effect of TGF-beta 2 on primitive murine hemopoietic stem and progenitor cells is dependent on age, genetic background, and serum factors. Immunology 2004; 173: 2486–2493
   Web of Science ®Google Scholar
• Jenei V., Zor K., Magyar K., Jakus J. Increased cell-cell adhesion, a novel effect of R-(-)-deprenyl. Neural Transmission 2005; 112: 1433–1445
   PubMed Web of Science ®Google Scholar
• Kakko I., Toimela T., Tahti H. The toxicity of pyrethroid compounds in neural cell cultures studied with total ATP, mitochondrial enzyme activity and microscopic photographing. Env. Toxicol. Pharmacol. 2004; 15: 95–102
   PubMed Web of Science ®Google Scholar
• Kim Y.-M., Chung H.-T., Kim S.-S., Han J.-A., Yoo Y.-M., Kim K.-M., Lee G.-H., Yun H.-Y., Green A., Li J., Simmons R. L., Billiar T. R. Nitric oxide protects PC12 cells from serum deprivation-induced apoptosis by cGMP-dependent inhibition of caspase signaling. J. Neruosci. 1999; 19: 6740–6747
   PubMed Web of Science ®Google Scholar
• Kitamura Y., Iida Y., Abe J., Ueda M., Mifune M., Kasuya F., Ohta M., Igarashi K., Saito Y., Saji H. Protective effect of zinc against ischemic neuronal injury in a middle cerebral artery occlusion model. J. Pharmacol. Sci. 2006; 100: 142–148
   PubMed Web of Science ®Google Scholar
• Koh S-H., Jung B., Song C. W., Kim Y., Kim Y. S., Kim S. H. 15-Deoxy-delta12,14-prostaglandin J2, a neuroprotectant or a neurotoxicant?. Toxicology 2005; 216: 232–243
   PubMed Web of Science ®Google Scholar
• Konings P. N.M., Makkink W. K., van Delft A. M.L., Ruigt G. S.F. Reversal by NGF of cytostatic drug-induced reduction of neurite outgrowth in rat dorsal root ganglia in vitro. Brain Res. 1994; 640: 195–204
   PubMed Web of Science ®Google Scholar
• Ksir C., Hakan R. L., Kellar K. J. Chronic nicotine and locomotor activity: influences of exposure dose and test dose. Psychopharmacology 1987; 92: 25–29
   PubMed Web of Science ®Google Scholar
• Levin E. D., Caldwell D. P. Low-dose mecamylamine improves learning of rats in the radial-arm maze repeated acquisition procedure. Neurobiol. Learn. Mem. 2006; 86: 117–122
   PubMed Web of Science ®Google Scholar
• Li F.-Q., Cheng X.-X., Liang X.-B., Wang X.-H., Xue B., He Q.-H., Wang X.-M., Han J.-S. Neurotrophic and neuroprotective effects of tripchlorolide, an extract of Chinese herb tripterygium wilfordii Hook F, on dopaminergic neurons. Exper. Neurol. 2003; 179: 28–37
   PubMed Web of Science ®Google Scholar
• Macauley S. L., Horsch A. D., Oterdoom M., Zheng M. H., Stewart G. R. The effects of transforming growth factor-β 2 on dopaminergic graft survival. Cell Transplantation 2004; 13: 245–252
   PubMed Web of Science ®Google Scholar
• Mannerstrom M., Toimela T., Ylikomi T., Tahti H. The combined use of human neural and liver cell lines and mouse hepatocytes improves the predictability of the neurotoxicity of selected drugs. Toxicol. Letters 2006; 165: 195–202
   PubMed Web of Science ®Google Scholar
• Marks M. J., Burch J. B., Collins A. C. Genetics of nicotine response in four inbred strains of mice. J. Pharmacol. Exper. Therap. 1983; 226: 291–302
   PubMed Web of Science ®Google Scholar
• Marx C. E., Jarskog L. F., Lauder J. M., Gilmore J. H., Lieberman J. A., Morrow A. L. Neurosteroid modulation of embryonic neuronal survival in vitro following anoxia. Brain Res. 2000; 871: 104–112
   PubMed Web of Science ®Google Scholar
• Matthews R. T., Ferrante R. J., Klivenyi P., Yang L., Klein A. M., Mueller G., Kaddurah-Daouk R., Beal M. F. Creatine and cyclocreatine attenuate MPTP neurotoxicity. Exper. Neurology 1999; 157: 142–149
   PubMed Web of Science ®Google Scholar
• Melchior C. L., Ritzmann R. F. Dehydroepiandrosterone is an anxiolytic in mice on the plus maze. Pharmacol. Biochem. Behav. 1994; 47: 427–441
   PubMed Web of Science ®Google Scholar
• Mena M. A., Davila V., Sulzer D. Neurotrophic effects of L-DOPA in postnatal midbrain dopamine neuron/cortical astrocyte cocultures. J. Neurochem. 1997; 69: 1398–1408
   PubMed Web of Science ®Google Scholar
• Miczek K. A., Fish E. W., De Bold J. F. Neurosteroids, GABA-A receptors, and escalated aggressive behavior. Horm. Behav. 2003; 44: 242–257
   PubMed Web of Science ®Google Scholar
• Minana M.-D., Hermenegildo C., Llanscola M., Montoliu C., Grisolia S., Felipo V. Carnitine and choline derivatives containing a trimethylamine group prevent ammonia toxicity in mice and glutamate toxicity in primary cultures of neurons. J. Pharmacol. Exp. Therap. 1996; 279: 194–199
   PubMed Web of Science ®Google Scholar
• Moriguchi T., Matsuura H., Itakura Y., Katsuki H., Saito H., Nishiyama N. Allixin, a phytoalexin produced by garlic, and its analogues as novel exogenous substances with neurotrophic activities. Life Sci., 1997; 61(14)1413–1420
   PubMed Web of Science ®Google Scholar
• Moser V. C., MacPhail R. C. Neurobehavioral effects of Triadimefon, a triazole fungicide, in male and female rats. Neurtoxicol. Teratol. 1989; 11: 285–293
   PubMed Web of Science ®Google Scholar
• Nagayama T., Sinor A. D., Simon R. P., Chen J., Graham S. H., Jin K., Greenberg D. A. Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures. J. Neurosci. 1999; 19: 2987–2995
   PubMed Web of Science ®Google Scholar
• O'Neill K., Chen S., Brinton R. D. Impact of the selective estrogen receptor modulator, raloxifene, on neuronal survival and outgrowth following toxic insults associated with aging and Alzheimer's disease. Exper. Neurol. 2004; 185: 63–80
   PubMed Web of Science ®Google Scholar
• Onoue S., Ohshima K., Endo K., Yajima T., Kashimoto K. PACAP protects neuronal PC12 cells from the cytotoxicity of human prion protein fragment 106–126. FEBS Letters 2002; 522: 65–70
   PubMed Web of Science ®Google Scholar
• Pentreath V. W., Slamon N. D. Astrocyte phenotype and prevention against oxidative damage in neurotoxicity. Hum. Exper. Toxicol. 2000; 19: 641–649
   PubMed Web of Science ®Google Scholar
• Pollack S., Young L., Bilsland J., Wilkie N., Ellis S., Hefti F., Broughton H., Harper S. The staurosporine-like compound L-753,000 (NB-506) potentiates the neurotrophic effects of neurotrophin-3 by acting selectively at the TrkA receptor. Amer. Soc. Pharmacol. Exper. Therap., 1999; 56: 185–195
   Google Scholar
• Pradhan S. N. Effects of nicotine on several schedules of behavior in rats. Arch. Int. Pharmacodyn., 1970; 183: 127–138
   PubMedGoogle Scholar
• Rauhut A. S., Neugebauer N., Dwoskin L. P., Bardo M. T. Effect of bupropion on nicotine self-administration in rats. Psychopharmacology 2003; 169: 1–9
   PubMed Web of Science ®Google Scholar
• Reddy D. S., Kulkarni S. K. The effects of neurosteroids on acquisition and retention of a modified passive-avoidance learning task in mice. Brain Res. 1998; 791: 108–116
   PubMed Web of Science ®Google Scholar
• Renis M., Cardile V., Russo A., Campisi A., Collova F. Glutamine synthetase activity and HSP70 levels in cultured rat astrocytes: effect of 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine. Brain Res. 1998; 783: 143–150
   PubMed Web of Science ®Google Scholar
• Romsicki Y., Sharom F. J. The membrane lipid environment modulates drug interactions with the p-glycoprotein multidrug transporter. Biochem. 1999; 38: 6887–6896
   PubMed Web of Science ®Google Scholar
• Sands S. F., Wright A. A. Enhancement and disruption of retention performance by ACTH in a choice task. Behav. Neural Biol. 1979; 27: 413–422
   PubMedGoogle Scholar
• Sarkadi B., Price E. M., Boucher R. C., Germann U. A., Scarborough G. A. Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase. J. Biol. Chem. 1992; 267: 4854–4858
   PubMed Web of Science ®Google Scholar
• Schense J. C., Bloch J., Aebischer P., Hubbell J. A. Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension. Nature Biotech., 2000; 18: 415–419
   PubMed Web of Science ®Google Scholar
• Schmid D., Ecker G., Kopp S., Hitzler M., Chiba P. Structure-activity relationship studies of propafenone analogs based on P-glycoprotein ATPase activity measurements. Biochem. Pharmacol. 1999; 58: 1447–1456
   PubMed Web of Science ®Google Scholar
• Sharom F. J., Yu X., Didiodato G., Chu J. W.K. Synthetic hydrophobic peptides are substrate for P-glycoprotein and stimulate drug transport. Biochem. J. 1996; 320: 421–428
   PubMed Web of Science ®Google Scholar
• Sharom F. J., Yu Z., Doige C. A. Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein. J. Biochem. 1993; 268: 24197–24202
   Google Scholar
• Sondell M., Lundborg G., Kanje M. Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J. Neurosci. 1999; 19: 5731–5740
   PubMed Web of Science ®Google Scholar
• Soriano F. X., Papadia S., Hofmann F., Hardingham N. R., Bading H. Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability. Neurosci. 2006; 26: 4509–4518
   Web of Science ®Google Scholar
• Sun Y., Maxwell G. D. Ciliary neurotrophic factor (CNTF) has a dose-dependent biphasic effect on the number of adrenergic cells which develop in avian trunk neural crest cultures. Neurosci. Let., 1994; 165: 1–4
   PubMed Web of Science ®Google Scholar
• Takebayashi M., Hayashi T., Su T.-P. Nerve growth factor-induced neurite sprouting in PC12 cells involves σ-1 receptors: Implications for antidepressants. J. Pharmacol. Exper. Therap. 2002; 303: 1227–1237
   PubMed Web of Science ®Google Scholar
• Teepker M., Anthes N., Fischer S., Krieg J.-C., Vedder H. Effects of oxidative challenge and calcium on ATP-levels in neuronal cells. NeuroToxicol., (in press). Neurotoxicology 2007; 28: 19–26
   PubMed Web of Science ®Google Scholar
• Thompson A. M., Swant J., Wagner J. Cocaine-induced modulation of long-term potentiation in the CA1 region of rat hippocampus. Neuropharmacology 2005; 49: 185–194
   PubMed Web of Science ®Google Scholar
• Toimela T., Tahti H. Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin. Arch. Toxicol. 2004; 78: 565–574
   PubMed Web of Science ®Google Scholar
• Vimard F., Nouvelot A., Duval D. Cytotoxic effects of an oxidative stress on neuronal-like pheochromocytoma cells (PC12). Biochem. Pharmacol. 1996; 51: 1389–1395
   PubMed Web of Science ®Google Scholar
• Wang J. M., Johnston P. B., Ball B. G., Brinton R. D. The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression. J. Neurosci. 2005a; 25: 4706–4718
   PubMed Web of Science ®Google Scholar
• Wang G., Qi C., Fan G.-H., Zhou H.-Y., Chen S.-D. PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone. FEBS Letters 2005b; 579: 4005–4011
   PubMed Web of Science ®Google Scholar
• Wejksza K., Rzeski W., Turski W. A., Hilgier W., Dybel A., Abrecht J. Ammonia at pathophysiologically relevant concentrations activates kynurenic acid synthesis in cultured astrocytes and neurons. NeuroToxicol. 2006; 539: 1–4
   Google Scholar
• Wiley J. L., Fagalde R. E., Buhler K. G., LaVecchia K. L., Balster R. L. Evaluation of 1,1,1-trichloroethane and flurothyl locomotor effects following diazepam treatment in mice. Pharmacol. Biochem. Behav. 2002; 71: 163–169
   PubMed Web of Science ®Google Scholar
• Williams E. J., Furness J., Walsh F. S., Doherty P. Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF. Development 1994; 120: 1685–1693
   PubMed Web of Science ®Google Scholar
• Windisch M., Hutter-Paier B., Lerkovic L., Imbimbo B., Villetti G. The protective effect of ganstigmine against amyloid beta 25-35 neurotoxicity on chicken cortical neurons is independent from the cholinesterase inhibition. Neurosci. Letters 2003; 341: 181–184
   PubMed Web of Science ®Google Scholar
• Young J. W., Finlayson K., Spratt C., Marston H. M., Crawford N., Kelly J. S., Sharkey J. Nicotine improves sustained attention in mice: Evidence for involvement of the α 7 nicotinic acetylcholine receptor. Neuropsychopharmacology 2004; 29: 891–900
   PubMed Web of Science ®Google Scholar