Evolution Of Clonal Cytogenetic Abnormalities in Aplastic Anemia

References

• Young, N.S. (2002) "Acquired aplastic anemia", Annals Internal Medicine, 136, 534— 546.
   PubMed Web of Science ®Google Scholar
• Maciejewski, J.P., Rivera, C., Kook, H., Dunn, D. and Young, N.S. (2001) "Relationship between bone marrow failure syndromes and the presence of glycophosphatidyl inositol-anchored protein-defi-cient clones", British Journal of Haematology, 115, 1015–1022.
   Google Scholar
• Dunn, D.E., Tanawattanacharoen, P., Boccuni, P., Nagakura, S., Green, S.W., Kirby, M.R.., et al. (1999) "Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes", Annals Internal Medicine, 131, 401 —408.
   Google Scholar
• Appelbaum, F.R., Barrall, J., Storb, R., Ramberg, R., Doney, K., Sale, G.E., et al. (1987) "Clonal cytogenetic abnormalities in patients with otherwise typical aplastic anemia", Experimental Hematology, 15, 1134–1139.
   Google Scholar
• Varma, N., Varma, S., Movafagh, A. and Garewal, G. (1995) "Unusual clonal cytogenetic abnormalities in aplastic anemia", American Journal of Hematology, 49, 256–257.
   Google Scholar
• Molldrem, ii., Caples, M., Mavroudis, D., Plante, M., Young, N.S., Barrett, A.J., et al. (1997) "Antithymocyte globulin for patients with myelodysplastic syndrome", British Journal of Haematology, 99, 699–705.
   PubMed Web of Science ®Google Scholar
• Molldrem, Li., Leifer, E., Bahceci, E., Saunthararajah, Y., Rivera, M., Dunbar, C., et al. (2002) "Antithymocyte globulin for treatment of the bone marrow failure associated with myelodysplastic syndromes", Annals Internal Medicine, 137, 156 — 163.
   Google Scholar
• Selleri, C., Maciejewski, J.P., Catalano, L., Ricci, P., Andretta, C., Luciano, L., et al. (2002) "Effects of cyclosporine on hematopoietic and immune functions in patients with hypoplastic myelodysplasia: in vitro and in vivo studies", Cancer, 95, 1911–1922.
   Google Scholar
• Kaito, K., Kobayashi, M., Katayama, T., Masuoka, H., Shimada, T., Nishiwaki, K., et al. (1998) "Long-term administration of G-CSF for aplastic anaemia is closely related to the early evolution of monosomy 7 MDS in adults", British Journal of Haematology, 103, 297— 303.
   Google Scholar
• Yamazaki, E., Kanamori, H., Taguchi, J., Harano, H., Mohri, H., Okubo, T., et al. (1997) "The evidence of clonal evolution with monosomy 7 in aplastic anemia following granulocyte colony-stimulating factor using the polymerase chain reaction", Blood Cells Molecules Diseases, 23, 213–218.
   PubMed Web of Science ®Google Scholar
• Bessho, M., Hotta, T., Ohyashiki, K., Takahashi, T., Mizoguchi, H., Asano, S., et al. (2003) "Multicenter prospective study of clonal complications in adult aplastic anemia patients following recombi-nant human granulocyte colony-stimulating factor (lenograstim) administration", International Journal of Hematology, 77, 152 — 158.
   Google Scholar
• Kojima, S., Hibi, S., Kosaka, Y., Yamamoto, M., Tsuchida, M., Mugishima, H., et al. (2000) "Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia", Blood, 96, 2049–2054.
   Google Scholar
• Bacigalupo, A., Brand, R., Oneto, R., Bruno, B., Socie, G., Passweg, J., et al. (2000) "Treatment of acquired severe aplastic anemia: bone marrow transplantation compared with immunosup-pressive therapy—The European Group for Blood and Marrow Transplantation experience", Seminars in Hematology, 37, 69–80.
   Google Scholar
• Maciejewski, J.P., Risitano, A., Sloand, EM., Nunez, O. and Young, N.S. (2002) "Distinct clinical outcomes for cytogenetic abnormalities evolving from aplastic anemia", Blood, 99, 3129–3135.
   Google Scholar
• Maciejewski, J.P., Follmann, D., Nakamura, R., Saunthararajah, Y., Rivera, CE., Simonis, T., et al. (2001) "Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome", Blood, 98, 3513–3519.
   PubMed Web of Science ®Google Scholar
• Sloand, EM., Maciejewski, J.P., Nakamura, R., Barrett, A.J. and Young, N.S. (2002) "Fas-mediated apoptosis is important in regulating cell replication and death in hematopoietic cells with trisomy-8 but not in cells with other chromosomal abnormalities", Blood, 100, 1 — 6.
   Google Scholar
• Young, N.S. and Barrett, A.J. (2002) Immune modulation of myelodysplasia: rationale and therapy. In The Myelodysplastic Syndromes: Pathobiology and Clinical Management, edited by J. Bennett. Pp 373–397. New York: Marcel Dekker.
   Google Scholar
• Tooze, JA., Marsh, J.C. and Gordon-Smith, E.C. (1999) "Clonal evolution of aplastic anaemia to myelodysplasia/acute myeloid leukaemia and paroxysmal nocturnal haemoglobinuria", Leukemia and Lymphoma, 33, 231–241.
   PubMed Web of Science ®Google Scholar
• Miescher, PA., Favre, H. and Beris, P. (1991) "Autoimmune myelodysplasias", Seminars in Hematology, 28, 322— 330.
   PubMed Web of Science ®Google Scholar
• Paquette, R.L., Tebyani, N., Franc, M., Ireland, P., Ho, W.G., Champlin, RE., et al. (1991) "Long-term outcome of aplastic anemia in adults treated with antithymocyte globulin: comparison with bone marrow transplantation", Blood, 85, 283–290.
   Google Scholar
• de Planque, MM., Kluin-Nelemans, H.C., van Krieken, H.J., Kluin, P.M., Brand, A., Beverstock, G.C., et al. (1988) "Evolution of acquired severe aplastic anaemia to myelodysplasia and subsequent leukaemia in adults", British Journal of Haematology, 70, 55–62.
   PubMed Web of Science ®Google Scholar
• Jameel, T., Anwar, M., Abdi, S.I., Saleem, M., Ahmad, P.A., Khattak, M.F., et al. (1997) "Aplastic anemia or aplastic preleukemic syndrome?", Annals of Hematology, 75, 189–193.
   PubMed Web of Science ®Google Scholar
• Young, N.S. and Maciejewski, J.P. (1995) Aplastic Anemia. In Hematology: Basic Priciples and Practice, edited by R. Hoffman. Pp 297— 331. Churchill Livingstone.
   Google Scholar
• Doney, K., Leisenring, W., Storb, R. and Appelbaum, F.R. (1997) "Primary treatment of acquired aplastic anemia: outcomes with bone marrow transplantation and immunosuppressive therapy. Seattle Bone Marrow Transplant Team", Annals of Internal Medicine, 126, 107–115.
   Google Scholar
• de Planque, MM., Bacigalupo, A., Wursch, A., Hows, J.M., Devergie, A., Frickhofen, N., et al. (1989) "Long-term follow-up of severe aplastic anaemia patients treated with antithymocyte globulin. Severe Aplastic Anaemia Working Party of the European Cooperative Group for Bone Marrow Transplantation (EBMT)", British Journal of Haematology, 73, 121–126.
   Google Scholar
• Socie, G., Henry-Amar, M., Bacigalupo, A., Hows, J., Tichelli, A., Ljungman, P., et al. (1993) "Malignant tumors occurring after treatment of aplastic anemia. European Bone Marrow Transplanta-tion-Severe Aplastic Anaemia Working Party", New England Journal of Medicine, 329, 1152 — 1157.
   Google Scholar
• Socie, G., Rosenfeld, S., Frickhofen, N., Gluckman, E. and Tichelli, A. (2000) "Late clonal diseases of treated aplastic anemia", Seminars in Hematology, 37, 91–101.
   PubMed Web of Science ®Google Scholar
• McHeyzer-Williams, L.J., Panus, J.F., Mikszta, J.A. and McHey-zer-Williams, M.G. (1999) "Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs", Journal of Experimental Medicine, 189, 1823–1838.
   Google Scholar
• Keung, Y.K., Pettenati, M.J., Cruz, J.M., Powell, B.L., Woodruff, R.D., Buss, D.H., et al. (2001) "Bone marrow cytogenetic abnormalities of aplastic anemia", American Journal of Hematology, 66, 167 — 171.
   Google Scholar
• Ohga, S., Ohara, A., Hibi, S., Kojima, S., Bessho, F., Tsuchiya, S., et al. (2002) "Treatment responses of childhood aplastic anaemia with chromosomal aberrations at diagnosis", British Journal of Haematology, 118, 313 — 319.
   Google Scholar
• Geary, C.G., Harrison, C.J., Philpott, N.J., et al. (1999) "Abnormal cytogenetic clones in patients with aplastic anaemia: response to immunosuppressive therapy", British Journal of Haematology, 104, 271 — 274.
   PubMed Web of Science ®Google Scholar
• Mikhailova, N., Sessarego, M., Fugazza, G., Caimo, A., De Filippi, S., Van Lint, M.T., et al. (1996) "Cytogenetic abnormalities in patients with severe aplastic anemia", Haematologica, 81, 418 —422.
   Google Scholar
• Bacigalupo, A., Bruno, B., Saracco, P., Di Bona, E., Locasciulli, A., Locatelli, F., et al. (2000) "Antilymphocyte globulin, cyclosporine, prednisolone, and granulocyte colony-stimulating factor for severe aplastic anemia: an update of the GITMO/EBMT study on 100 patients. European Group for Blood and Marrow Transplantation (EBMT) Working Party on Severe Aplastic Anemia and the Gruppo Italiano Trapianti di Midolio Osseo (GITMO)", Blood, 95, 1931 — 1934.
   Google Scholar
• Frickhofen, N., Heimpel, H., Kaltwasser, J.P. and Schrezenmeier, H. (2003) "Antithymocyte globulin with or without cyclosporin A: 11-year follow-up of a randomized trial comparing treatments of aplastic anemia", Blood, 101, 1236–1242.
   Google Scholar
• Fuhrer, M., Burdach, S., Ebell, W., Gadner, H., Haas, R., Harbott, J., et al. (1998) "Relapse and clonal disease in children with aplastic anemia (AA) after immunosuppressive therapy (1ST): the SAA 94 experience. German/Austrian Pediatric Aplastic Anemia Working Group", Klin Padiatric, 210, 173— 179.
   Google Scholar
• Ohara, A., Kojima, S., Okamura, J., Inada, H., Kigasawa, H., Hibi, S., et al. (2002) "Evolution of myelodysplastic syndrome and acute myelogenous leukaemia in children with hepatitis-associated aplas-tic anaemia", British Journal of Haematology, 116, 151–154.
   Google Scholar
• Ishiyama, K., Karasawa, M., Miyawalci, S., Ueda, Y., Noda, P., Wakita, A., et al. (2002) "Aplastic anaemia with 13q-: a benign subset of bone marrow failure responsive to immunosuppressive therapy", British Journal of Haematology, 117, 747–750.
   Google Scholar
• Brodsky, R.A., Sensenbrenner, L.L., Smith, B.D., Dorr, D., Seaman, P.J., Lee, S.M., et al. (2001) "Durable treatment-free remission after high-dose cyclophosphamide therapy for previously untreated severe aplastic anemia", Annals Internal of Medicine, 135, 477–483.
   Google Scholar
• Tisdale, J.F., Maciejewski, J.P., Nunez, O., Rosenfeld, S.J. and Young, N.S. (2002) "Late complications following treatment for severe aplastic anemia (SAA) with high-dose cyclophosphamide (Cy): follow-up of a randomized trial", Blood, 100, 4668–4670.
   Google Scholar
• Kojima, S., Ohara, A., Tsuchida, M., Kudoh, T., Hanada, R., Okimoto, Y., et al. (2002) "Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children", Blood, 100, 786— 790.
   Google Scholar
• Rosenfeld, S., Follmann, D., Nunez, O. and Young, N.S. (2003) "Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome", JAMA, 289, 1130–1135.
   Google Scholar
• Sloand, E., Fuhrer, M., Johnson, S., Basu, A., Maciejewslci, J.P., Risitano, A., et al. (2002) "Preferential inhibition of trisomy 8 progenitor cell growth by autologous CD8 + V-beta-restricted T cells in patients with trisomy 8 and myelodysplasia", Blood, 100, 166A.
   Web of Science ®Google Scholar
• Michalova, K., Musilova, J. and Zemanova, Z. (1990) "Cytogenetic abnormalities in 532 patients with myeloid leukemias and myelo-dyplastic syndrome. The Czechoslovak MDS Cooperative Group", Czech Medicine, 13, 133 — 144.
   PubMedGoogle Scholar
• Sole, F., Espinet, B., Sanz, G.F., Cervera, J., Calasanz,Luno,E., et al. (2000) "Incidence, characterization and prognostic significance of chromosomal abnormalities in 640 patients with primary myelodysplastic syndromes. Grupo Cooperativo Espanol de Citogenetica Hematologica", British Journal of Haematology, 108, 346— 356.
   Google Scholar
• Vila, L., Charrin, C., Archimbaud, E., Treille-Ritouet, D., Fraisse, J., Felman, P., et al. (1990) "Correlations between cytogenetics and morphology in myelodysplastic syndromes", Blut, 60, 223–227.
   Google Scholar
• Bernasconi, P., Alessandrino, E.P., Boni, M., Bonfichi, M., Morra, E., Lazzarino, M., et al. (1994) "Karyotype in myelodysplastic syndromes: relations to morphology, clinical evolution, and survival", American Journal of Hematology, 46, 270–277.
   Google Scholar
• Knapp, R.H., Dewald, G.W. and Pierre, R.V. (1985) "Cytogenetic studies in 174 consecutive patients with preleukemic or myelodys-plastic syndromes", Mayo Clinic Proceedings, 60, 507–516.
   PubMed Web of Science ®Google Scholar
• Suciu, S., Kuse, R., Weh, H.J. and Hossfeld, D.K. (1990) "Results of chromosome studies and their relation to morphology, course, and prognosis in 120 patients with de novo myelodysplastic syndrome", Cancer Genetics and Cytogenetics, 44, 15–26.
   PubMed Web of Science ®Google Scholar
• Maciejewslci, J.P., Selleri, C., Sato, T., Anderson, S. and Young, N.S. (1996) "A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiat-ing cells) in acquired aplastic anemia", Blood, 88, 1983–1991.
   Google Scholar
• Pedersen, B. (1997) "MDS and AML with trisomy 8 as the sole chromosome aberration show different sex ratios and prognostic profiles: a study of 115 published cases", American Journal Hematology, 56, 224–229.
   PubMed Web of Science ®Google Scholar
• Kennedy, B., Rawstron, A., Carter, C., et al. (1997) "Campath-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia", Blood, 99, 2245–2247.
   Google Scholar
• Slovak, M.L., Kopecky, K.J., Cassileth, P.A., Harrington, D.H., Theil, KS., Mohamed, A., et al. (2000) "Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/ Eastern Cooperative Oncology Group Study", Blood, 96, 4075 — 4083.
   Google Scholar
• Grimwade, D., Walker, H., Oliver, F., Wheatley, K., Harrison, C., Harrison, G., et al. (1998) "The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties", Blood, 92, 2322 — 2333.
   Google Scholar
• Greenberg, P., Cox, C., LeBeau, MM., Fenaux, P., Morel, P., Sanz, G., et al. (1997) "International scoring system for evaluating prognosis in myelodysplastic syndromes", Blood, 89, 2079 — 2088.
   Google Scholar
• de Souza, FT., Ornellas, M.H., Otero, D.C., Tabak, D. and Abdelhay, E. (1997) "Chromosomal alterations associated with evolution from myelodysplastic syndrome to acute myeloid leuke-mia", Leukemia Research, 24, 839–848.
   Google Scholar
• Elghetany, MT., Hudnall, S.D. and Gardner, F.H. (1997) "Peripheral blood picture in primary hypocellular refractory anemia and idiopathic acquired aplastic anemia: an additional tool for differential diagnosis", Haematologica, 82, 21— 24.
   PubMed Web of Science ®Google Scholar
• Tuzuner, N., Cox, C., Rowe, J.M., Watrous, D. and Bennett, J.M. (1995) "Hypocellular myelodysplastic syndromes (MDS): new proposals", British Journal of Haematology, 91, 612–617.
   PubMed Web of Science ®Google Scholar
• Goyal, R., Qawi, H., Ali, I., Dar, S., Mundle, S., Shetty, V., et al. (1999) "Biologic characteristics of patients with hypocellular myelodysplastic syndromes", Leukemia Research, 23, 357–364.
   Google Scholar
• Riccardi, A., Giordano, M., Girino, M., Cazzola, M., Montecucco, CM., Cassano, E., et al. (1987) "Refractory cytopenias: clinical course according to bone marrow cytology and cellularity", Blut, 54, 153 — 163.
   Google Scholar
• Jonasova, A., Neuwirtova, R., Cermak, J., Vozobulova, V., Mcikova, K., Siskova, M., et al. (1998) "Cyclosporin A therapy in hypoplastic MDS patients and certain refractory anaemias without hypoplastic bone marrow", British Journal of Haematology, 100, 304— 309.
   Google Scholar
• Catalano, L., Selleri, C., Califano, C., Luciano, L., Volpicelli, M., Rocco, S., et al. (2000) "Prolonged response to cyclosporin-A in hypoplastic refractory anemia and correlation with in vitro studies", Haematologica, 85, 133— 138.
   Google Scholar
• Killick, S.B., Mufti, G., Cavenagh, J.D., Mijovic, A., Peacock, J.L., Gordon-Smith, E.C., et al. (2003) "A pilot study of antithymocyte globulin (ATG) in the treatment of patients with low-risk' myelodysplasia", British Journal of Haematology, 120, 679–684.
   PubMed Web of Science ®Google Scholar
• Steensma, D.P., Dispenzieri, A., Moore, S.B., Schroeder, G. and Tefferi, A. (2003) "Antithymocyte globulin has limited efficacy and substantial toxicity in unselected anemic patients with myelodys-plastic syndrome", Blood, 101, 2156–2158.
   Google Scholar
• Saunthararajah, Y., Nakamura, R., Nam, J.-M., Robyn, J., Loberiza, F., Maciejewski, J.P., et al. (2000) "HLA DR15 (DR2) is Over-represented in Myelodysplastic Syndrome and Aplastic Anemia, and Predicts a Response to Immunosuppression in Myelodysplastic Syndrome", Blood, 100, 1570 —1574.
   Google Scholar
• Kojima, S., Ohara, A., Tsuchida, M., Kudoh, T., Hanada, R., Okimoto, Y., et al. (2002) "Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children", Blood, 100, 786— 790.
   Google Scholar