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Research Article

Regulation of CD23 expression by Notch2 in B-cell chronic lymphocytic leukemia

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Pages 157-165 | Published online: 01 Jul 2009

REFERENCES

  • Rozman, C. and Montserrat, E. (1995) "Chronic lympho-cytic leukemia", New England Journal of Medicine, 333, 1052— 1057.
  • Zwiebel, J.A. and Cheson, B.D. (1998) "Chronic lympho-cytic leukemia: staging and prognostic factors", Seminars in Oncology, 25, 42–59.
  • Chiorazzi, N. and Ferrarini, M. (2003) "B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor", Annual Review in Immunology, 21, 841–894.
  • Orchard, J.A., Ibbotson, R.E., Davis, Z., Wiestner, A., Rosenwald, A., Thomas, P.W., et al. (2004) "ZAP-70 expression and prognosis in chronic lymphocytic leukaemia", Lancet, 363, 105–111.
  • Sarfati, M., Bron, D., Lagneaux, L., Fonteyn, C., Frost, H. and Delespesse, G. (1988) "Elevation of IgE-binding factors in serum of patients with B cell-derived chronic lymphocytic leukemia", Blood, 71, 94— 98.
  • Lowe, J., Brown, B., Hardie, D., Richardson, P. and Ling, N. (1989) "Soluble forms of CD21 and CD23 antigens in the serum in B cell chronic lymphocytic leukaemia", Immunology Letters, 20, 103–109.
  • Reinisch, W., Willheim, M., Hilgarth, M., Gasche, C., Mader, R., Szepfalusi, S., et al. (1994) "Soluble CD23 reliably reflects disease activity in B-cell chronic lymphocytic leukemia", Journal of Clinical Oncology, 12, 2146–2152.
  • Molica, S., Levato, D., Dell'Olio, M., Matera, R., Minervini,M., Dattilo, A., et al. (1996) "Cellular expression and serum circulating levels of CD23 in B-cell chronic lymphocytic leukemia. Implications for prognosis", Haematologica, 81, 428–433.
  • Sarfati, M., Chevret, S., Chastang, C., Biron, G., Stryck-mans, P., Delespesse, G., et al. (1996) "Prognostic importance of serum soluble CD23 level in chronic lymphocytic leukemia", Blood, 88, 4259–4264.
  • Knauf, W.U., Langenmayer, I., Ehlers, B., Mohr, B., Adorf,D., Nerl, C.H., et al. (1997) "Serum levels of soluble CD23, but not soluble CD25, predict disease progression in early stage B-cell chronic lymphocytic leukemia", Leukemia and Lymphoma, 27, 523–532.
  • Leotard, S., Chastang, C., Travade, P., Jaudon, Tournilhac, 0., Baudet, S., et al. (2000) "Prognostic relevance of a scoring system based on clinical and biological parameters in early chronic lymphocytic leukemia", The Hematology Journal, 1, 301–306.
  • Lesesve, J.F., Florence, A.M., Maynadie, G.M. and Feugier, P. (2001) "Prognostic relevance of soluble CD23 levels in CLL", The Hematology Journal, 2, 355.
  • DiRaimondo, F., Albitar, M., Huh, Y., O'Brien, S., Montillo, M., Tedeschi, A., et al. (2002) "The clinical and diagnostic relevance of CD23 expression in the chronic lymphoproliferative disease", Cancer, 94, 1721–1730.
  • Molica, S., Levato, D., Cascavilla, N., Levato, L. and Musto, P. (1999) "Clinico-prognostic implications of simultaneous increased serum levels of soluble CD23 and beta2-micro-globulin in B-cell chronic lymphocytic leukemia", European Journal of Haematology, 62, 117–122.
  • Dighiero, G. (2002) "Is chronic lymphocytic leukemia one disease?", Haematologica, 87, 1233–1235.
  • Delespesse, G., Suter, U., Mossalayi, D., Bettler, B., Sarfati, M., Hofstetter, H., et al. (1991) "Expression, structure, and function of the CD23 antigen", Advances in Immunology, 49, 149–191.
  • Mossalayi, M.D., Arock, M. and Debre, P. (1997) "CD23/ Fc epsilon RII: signaling and clinical implication", Interna-tional Reviews in Immunology, 16, 129–146.
  • Sarfati, M., Fournier, S., Christoffersen, M. and Biron, G. (1990) "Expression of CD23 antigen and its regulation by IL-4 in chronic lymphocytic leukemia", Leukemia Research, 14, 47–55.
  • Barnett, D. and Reilly, J.T. (1989) "Lack of correlation between cell surface activation antigen expression and clinical stage in B-CLL", British Journal of Haematology, 73, 572.
  • Dadmarz, R. and Cawley, J.C. (1988) "Heterogeneity of CLL: high CD23 antigen and alpha IFN receptor expression are features of favourable disease and of cell activation", British Journal of Haematology, 68, 279— 282.
  • Schwarzmeier, J.D., Shehata, M., Hilgarth, M., Marschitz,I., Louda, N., Hubmann, R., et al. (2002) "The role of soluble CD23 in distinguishing stable and progressive forms of B-chronic lymphocytic leukemia", Leukemia and Lympho-ma, 43, 549 — 554.
  • Heintel, D., Schwarzinger, I., Chizzali-Bonfadin, C., Thal-hammer, R., Schwarzmeier, J., Fritzer-Szekeres, M., et al. (2001) "Association of CD38 antigen expression with other prognostic parameters in early stages of chronic lymphocytic leukemia", Leukemia and Lymphoma, 42, 1315–1321.
  • Lampert, IA., Wotherspoon, A., Van Noorden, S. and Hasserjian, R.P. (1999) "High expression of CD23 in the proliferation centers of chronic lymphocytic leukemia in lymph nodes and spleen", Human Pathology, 30, 648— 654.
  • Lopez-Matas, M., Rodriguez-Justo, M., Morilla, R., Catovs-ky, D. and Matutes, E. (2000) "Quantitative expression of CD23 and its ligand CD21 in chronic lymphocytic leuke-mia", Haematologica, 85, 1140–1145.
  • Kintner, C. and Sugden, B. (1981) "Identification of antigenic determinants unique to the surfaces of cells transformed by Epstein-Barr virus", Nature, 294, 458–460.
  • Thorley-Lawson, D.A., Nadler, L.M., Bhan, A.K. and Schooley, R.T. (1985) "BLAST-2 [EBVCS], an early cell surface marker of human B cell activation, is superinduced by Epstein Barr virus", Journal of Immunology, 134, 3007–3012.
  • Kikutani, H., Suemura, M., Owaki, H., Nakamura, H., Sato, R., Yamasaki, K., et al. (1986) "Fc epsilon receptor, a specific differentiation marker transiently expressed on mature B cells before isotype switching", Journal of Experi-mental Medicine, 164, 1455–1469.
  • Waldschmidt, T.J., Conrad, D.H. and Lynch, RG. (1989) "Expression of B cell surface receptors. II. IL-4 can accelerate the developmental expression of the murine B cell IgE Fc receptor", Journal of Immunology, 143, 2820 — 2827.
  • Kijimoto-Ochiai, S. (2002) "CD23 (the low-affinity IgE receptor) as a C-type lectin: a multidomain and multifunctional molecule", Cellular and Molecular Life Sciences, 59, 648— 664.
  • Capron, M., Truong, M.J., Aldebert, D., Gruart, V., Suemura, M., Delespesse, G., et al. (1991) "Heterogeneous expression of CD23 epitopes by eosinophils from patients. Relationships with IgE-mediated functions", European Jour-nal of Immunology, 21, 2423–2429.
  • Dugas, B., Paul-Eugene, N., Coqueret, 0., Mencia-Huerta, J.M. and Braquet, P. (1992) "Possible role of CD23 in allergic diseases", Research in Immunology, 143, 448–451.
  • Kehry, M.R. and Yamashita, L.C. (1989) "Low-affinity IgE receptor (CD23) function on mouse B cells: role in IgE-dependent antigen focusing", Proceedings of the National Academy of Sciences of the United States of America, 86, 7556 — 7560.
  • Karagiannis, S.N., Warrack, J.K., Jennings, K.H., Murdock, P.R., Christie, G., Moulder, K., et al. (2001) "Endocytosis and recycling of the complex between CD23 and HLA-DR in human B cells", Immunology, 103, 319–331.
  • Aubry, J.P., Pochon, S., Graber, P., Jansen, KU. and Bonnefoy, J.Y. (1992) "CD21 is a ligand for CD23 and regulates IgE production", Nature, 358, 505–507.
  • Bjorck, P., Elenstrom-Magnusson, C., Rosen, A., Severn-son, E. and Paulie, S. (1993) "CD23 and CD21 function as adhesion molecules in homotypic aggregation of human B lymphocytes", European Journal of Immunology, 23, 1771 — 1775.
  • Rao, M., Lee, W.T. and Conrad, D.H. (1987) "Character-ization of a monoclonal antibody directed against the murine B lymphocyte receptor for IgE", Journal of Immunology, 138, 1845 —1851.
  • Lee, B.W., Simmons, C.-F.J., Wileman, T. and Geha, R.S. (1989) "Intracellular cleavage of newly synthesized low affinity Fc epsilon receptor (Fc epsilon R2) provides a second pathway for the generation of the 28-kDa soluble Fc epsilon R2 fragment", Journal of Immunology, 142, 1614 — 1620.
  • Christie, G., Barton, A., Bolognese, B., Buckle, D.R., Cook, R.M., Hansbury, M.J., et al. (1997) "IgE secretion is attenuated by an inhibitor of proteolytic processing of CD23 (Fc epsilonRII)", European Journal of Immunology, 27, 3228–3235.
  • Marolewski, A.E., Buckle, D.R., Christie, G., Eamshaw, D.L., Flamberg, P.L., Marshall, L.A., et al. (1998) "CD23 (FcepsilonRII) release from cell membranes is mediated by a membrane-bound metalloprotease", Biochemical Journal, 333, 573 — 579.
  • Letellier, M., Sarfati, M. and Delespesse, G. (1989) "Mechanisms of formation of IgE-binding factors (soluble CD23) — I. Fc epsilon R II bearing B cells generate IgE-binding factors of different molecular weights", Molecular Immunology, 26, 1105–1112.
  • Gordon, J., Cairns, J.A., Liu, Y.J., Flores-Romo, L., MacLennan, IC., Jansen, KU., et al. (1991) "Role of membrane and soluble CD23 in lymphocyte physiology", Monographs in Allergy, 29, 156— 168.
  • Delespesse, G., Sarfati, M., Wu, C.Y., Fournier, S. and Letellier, M. (1992) "The low-affinity receptor for IgE", Immunological Reviews, 125, 77–97.
  • Wendel-Hansen, V., Riviere, M., Uno, M., jansson, I., Szpirer, J., Islam, M.Q., et al. (1990) "The gene encoding CD23 leukocyte antigen (FCE2) is located on human chromosome 19", Somatic Cell and Molecular Genetics, 16, 283–286.
  • Yokota, A., Kikutani, H., Tanaka, T., Sato, R., Barsumian, E.L., Suemura, M., et al. (1988) "Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression", Cell, 55, 611 — 618.
  • Fournier, S., Tran, I.D., Suter, U., Biron, G., Delespesse, G. and Sarfati, M. (1991) "The in vivo expression of type B CD23 mRNA in B-chronic lymphocytic leukemic cells is associated with an abnormally low CD23 upregulation by IL-4: comparison with their normal cellular counterparts", Leukemia Research, 15, 609–618.
  • Alizadeh, A.A., Eisen, M.B., Davis, R.E., Ma, C., Lossos, IS., Rosenwald, A., et al. (2000) "Distinct types of diffuse large B-cell lymphoma identified by gene expression profil-ing", Nature, 403, 503 — 511.
  • Hagen, M., Sacco, R.E., Sandor, M., Best, C., Nambu, M. and Lynch, R.G. (1995) "The Fc epsilon RII/CD23 gene is actively transcribed during all stages of murine B-lymphocyte development", Molecular Immunology, 32, 1245–1257.
  • Goller, M.E., Kneitz, C., Mehringer, C., Muller, K., Jelley-Gibbs, D.M., Gosselin, E.J., et al. (2002) "Regulation of CD23 isoforms on B-chronic lymphocytic leukemia", Leu-kemia Research, 26, 795–802.
  • Yokota, A., Yukawa, K., Yamamoto, A., Sugiyama, K., Suemura, M., Tashiro, Y., et al. (1992) "Two forms of the low-affinity Fc receptor for IgE differentially mediate endocytosis and phagocytosis: identification of the critical cytoplasmic domains", Proceedings of the National Academy of Sciences of the United States of America, 89, 5030–5034.
  • Fournier, S., Yang, L.P., Delespesse, G., Rubio, M., Biron, G. and Sarfati, M. (1995) "The two CD23 isoforms display differential regulation in chronic lymphocytic leukaemia", British Journal of Haematology, 89, 373— 379.
  • Fournier, S., Delespesse, G., Rubio, M., Biron, G. and Sarfati, M. (1992) "CD23 antigen regulation and signaling in chronic lymphocytic leukemia", Journal of Clinical Investiga-tion, 89, 1312–1321.
  • Delespesse, G., Hofstetter, H., Sarfati, M., Suter, U., Nakajima, T., Frost, H., et al. (1989) "Human Fc epsilon Rh. Molecular, biological and clinical aspects", Chemical Immunology, 47, 79–105.
  • Hubmann, R., Schwarzmeier, J.D., Shehata, M., Hilgarth,M., Duechler, M., Dettke, M., et al. (2002) "Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia", Blood, 99, 3742–3747.
  • Ling, P.D., Hsieh, J.J., Ruf, I.K., Rawlins, D.R. and Hayward, S.D. (1994) "EBNA-2 upregulation of Epstein-Barr virus latency promoters and the cellular CD23 promoter utilizes a common targeting intermediate, CBF1", Journal of Virology, 68, 5375–5383.
  • Zimber-Strobl, U., Strobl, L.J., Meitinger, C., Hinrichs, R., Sakai, T., Furukawa, T., et al. (1994) "Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hair-less", EMBO Journal, 13, 4973–4982.
  • Henkel, T., Ling, P.D., Hayward, S.D. and Peterson, M.G. (1994) "Mediation of Epstein-Barr virus EBNA2 transacti-vation by recombination signal-binding protein J kappa", Science, 265, 92–95.
  • Hsieh, J.J., Nofziger, D.E., Weinmaster, G. and Hayward, S.D. (1997) "Epstein-Barr virus immortalization: Notch2 interacts with CBF1 and blocks differentiation", Journal of Virology, 71, 1938–1945.
  • Artavanis-Tsakonas, S., Rand, M.D. and Lake, R.J. (1999) "Notch signaling: cell fate control and signal integration in development", Science, 284, 770–776.
  • Nickoloff, B.J., Osborne, B.A. and Miele, L. (2003) "Notch signaling as a therapeutic target in cancer: a new approach to the development of cell fate modifying agents", Oncogene, 22, 6598— 6608.
  • Bertrand, F.E., Eckfeldt, C.E., Lysholm, A.S. and LeBien, T.W. (2000) "Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells", Leukemia, 14, 2095–2102.
  • Ohishi, K, Varnum-Finney, B., Flowers, D., Anasetti, C., Myerson, D. and Bernstein, I.D. (2000) "Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1", Blood, 95, 2847–2854.
  • Duechler, M., Schwarzmeier, J., Shehata, M., Hoelbl, A., Hilgarth, M. and Hubmann, R. (2004) "Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2", Leukemia in print.
  • Witt, CM., Hurez, V., Swindle, CS., Hamada, Y. and Klug, C.A. (2003) "Activated Notch2 potentiates CD8 lineage maturation and promotes the selective development of B1 B cells", Molecular and Cell Biology, 23, 8637–8650.
  • Witt, CM., Won, W.J., Hurez, V. and Klug, CA. (2003) "Notch2 haploinsufficiency results in diminished B1 B cells and a severe reduction in marginal zone B cells", Journal of Immunology, 171, 2783–2788.
  • Kuroda, K., Han, H., Tani, S., Tanigaki, K., Tun, T., Furukawa, T., et al. (2003) "Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway", Immunity, 18, 301–312.
  • Saito, T., Chiba, S., Ichikawa, M., Kunisato, A., Asai, T., Shimizu, K., et al. (2003) "Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development", Immunity, 18, 675–685.
  • Tanigaki, K., Han, H., Yamamoto, N., Tashiro, K., Ikegawa, M., Kuroda, K., et al. (2002) "Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells", Nature Immunology, 3, 443–450.
  • Hayakawa, K. and Hardy, R.R. (2000) "Development and function of B-1 cells", Current Opinion in Immunology, 12, 346— 353.
  • Bikah, G., Carey, J., Ciallella, JR., Tarakhovsky, A. and Bondada, S. (1996) "CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells", Science, 274, 1906–1909.
  • Murakami, M., Tsubata, T., Okamoto, M., Shimizu, A., Kumagai, S., Imura, H., et al. (1992) "Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice", Nature, 357, 77–80.
  • Ellisen, L.W., Bird, J., West, D.C., Soreng, A.L., Reynolds, T.C., Smith, S.D., et al. (1991) "TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms", Cell, 66, 649–661.
  • Radtke, F., Wilson, A., Mancini, S.J. and MacDonald, H.R. (2004) "Notch regulation of lymphocyte development and function", Nature Immunology, 5, 247–253.
  • Girard, L., Hanna, Z., Beaulieu, N., Hoemann, C.D., Simard, C., Kozak, C.A., et al. (1996) "Frequent provirus insertional mutagenesis of Notchl in thymomas of MNITVD/ myc transgenic mice suggests a collaboration of c-myc and Notchl for oncogenesis", Genes & Development, 10, 1930 — 1944.
  • Fitzgerald, K., Harrington, A. and Leder, P. (2000) "Ras pathway signals are required for notch-mediated oncogen-esis", Oncogene, 19, 4191–4198.
  • Caligaris-Cappio, F. (1996) "B-chronic lymphocytic leuke-mia: a malignancy of anti-self B cells", Blood, 87, 2615–2620.
  • Kuppers, R., Klein, U., Hansmann, M.L. and Rajewsky, K. (1999) "Cellular origin of human B-cell lymphomas", New England Journal of Medicine, 341, 1520 — 1529.
  • Carsetti, R., Rosado, M.M. and Wardmann, H. (2004) "Peripheral development of B cells in mouse and man", Immunological Reviews, 197, 179 — 191.
  • Stevenson, F.K. and Caligaris-Cappio, F. (2004) "Chronic lymphocytic leukemia: revelations from the B-cell receptor", Blood, 103, 4389 — 4395.
  • Micchelli, C.A., Esler, W.P., Kimberly, W.T., Jack, C., Berezovska, 0., Kornilova, A., et al. (2003) "Gamma-secretase/presenilin inhibitors for Alzheimer's disease pheno-copy Notch mutations in Drosophila", FASEB Journal, 17, 79–81.
  • Das, I., Craig, C., Funahashi, Y., Jung, K.M., Kim, T.W., Byers, R., et al. (2004) "Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and func-tion", Journal of Biological Chemistry, 279, 30771 — 30780.

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