20
Views
1
CrossRef citations to date
0
Altmetric
Case Report

Natural killer cell lymphoma/leukemia with homozygous loss of p27/kip1

, , &
Pages 919-923 | Received 24 Dec 2004, Published online: 03 Aug 2009

REFERENCES

  • Feuillard J, Jacob MC, Valensi F, Maynadie M, Gressin R, Chaperot L, Amoulet C, Baudouin FB, Drenou B, Duchayne E, Falkenrodt A, Garand R, Homolle E, Husson E, Husson B, Kuhlein E, Calvez GL, Sainty D, Sotto MF, Trimoreau F, Bene MC. Clinical and biologic features of CD4 + CD56 + malignancies. Blood 2002;99: 1556–1563.
  • Chan JKC, Jaffe ES, Ralfkiaer E. Blastic NK-cell lymphoma. In: Jaffe ES, Harris NL, Stein H, Vardiman JW, editors. Tumors of hematopoietic and lymphoid tissues. Lyon, France: IARC Press; 2001. pp. 214–215.
  • Siu LL, Chan JK, Kwong YL. Natural killer cell malignancies: clincopathologic and molecular features. Histol Histopathol 2002;17:593–554.
  • Wong KF, Chan JK, Yu PH, So CC. A man with natural killer cell lymphoma showing 46, XX and deletion 6q. Cancer Genet Cytogenet 1999;112:165–168.
  • Zhang Y, Wong KF, Siebert R, Matthiesen P, Harder S, Eimermacher H, Feller AC, Schlegelberger B. Chromosome aberrations are restricted to the CD56 +, CD3- tumor cell population in natural killer cell lymphomas: a combined immunophenotyping and FISH study. Br J Haematol 1999;105:737–742.
  • Hamaguchi H, Yamaguchi M, Nagata K, Koike E, Imagunbai M, Tsurukubo Y, Yamamoto K. Aggressive natural killer cell lymphoma/leukemia with clonal der(3)t(1;3)(q12;p25), del(6)(q13) and del(13)(q12q14). Cancer Genet Cytogenet 2001;130: 150–154.
  • Leroux D, Mugneret F, Callanan M, Weiss I, Dastugu N, Feuillard J, LeMee F, Plessis G, Talmant P, Gachard N, Uettwiller F, Pages MP, Mozziconacci MJ, Eclache V, Sibille C, Avet-Loiseau H, Pochitaloff ML, on behalf of Groupe Francais de Cytogenetique Hematologique (GFCH). CD4 +, CD56 + DC2 acute leukemia is characterized by recurrent clonal chromosomal changes affecting 6 major targets: a study of 21 cases by the Groupe Francais de Cytogenetique Hematologique. Blood 2002;99: 4154–4159.
  • Mao X, Onadim Z, Price EA, Child F, Lillington DM, Russel R, Young BD, Wittaker S. Genomic alterations in blastic NK/ extranodal NK-like T-cell lymphoma with cutaneous involve-ment. J Invest Dermatol 2003;121:618–627.
  • Aissani B, Bonan C, Baccichet A, Sinnet D. Childhood acute lymphoblastic leukemia: is there a tumor suppressor gene in chromosome 12p12.3? Leukemia Lymphoma 1999;34:231–239.
  • Benzer R, Bernheim A, L,eConiat M, Vechione D, Pacot A, Daniel MT, Flandrim G. Abnormalities of the short arm of the chromosome 12 in acute non-lymphoblastic leukemia and dysmeylopoietic syndrome. Cancer Genet Cytogenet 1986;19: 281–289.
  • Chan LC, Kwong YL, Lin HW, Lee CP, Chan AYY. Deletion 12p in de novo acute myeloid leukemia. Cancer Genet Cytogenet 1992;62: 47–49.
  • Pietenpol JA, Bohlander SK, Sato Y, Papadopoulos N, Lin B, Friedman C, Trask BJ, Roberts JM, Kinzler KW, Rowley JD, Vogelstein B. Assignment of the human p27Ikipl gene to 12p13 and its analysis in leukemia. Cancer Res 1995;55: 1206–1210.
  • Siu LP, Wong KF, Chan JK, Kwong YL. Comparative genomic hybridization of natural killer cell lymphoma/leuke-mia. Recognition of consistent patterns of genetic alterations. Am J Pathol 1999;155:1419–1425.
  • Gloub TR, Barker GF, Lovett M, Gilliland DG. Fusion of PDGF receptor to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translo-cation. Cell 1994;77:307–311.
  • Hwang HC, Martins CP, Bronkhorst Y, Randel E, Berns A, Fero M, Clurman BE. Identification of oncogenes collaborat-ing with p27Ikipl loss by insertional mutagenesis and high throughput insertion site analysis. PNAS 2002;99: 11293–11298.
  • Martins CP, Berns A. Loss of p27 (Kipl) but not p21 (Cip 1 ) decreases survival and synergizes with MYC in murine lymphomagenesis. EMBO J 2002;21:3739–3748.
  • Morosetti R, Kawamata N, Gombart AF, Miller CW, Hatta Y, Hirama T, Said JW, Tomonaga M, Koeffier HP. Alterations of the p27Ikipl gene in non-Hodgkin's lymphomas and adult T-cell leukemia/lymphoma. Blood 1995;86: 1924–1930.
  • Seriu T, Erz D, Bartam CR Germline configuration of the p27Ikipl gene in childhood acute lymphoblastic leukemia (ALL). Leukemia 1996;10:345.
  • Takeuchi S, Bartam CR, Miller CW, Reiter A, Seriu T, Zimmermann M, Schrappe M, Mori N, Slater J, Miyoshi I, Koeffier HP. Acute lymphoblastic leukemia of childhood: identification of two distinct regions of deletion on the short arm of chromosome 12 in the region of TEL and KIP1. Blood 1996;87: 3368–3374.
  • Castanedo MV, Lee MH, Latres E, Polyak K, Lacombe L, Montgomery K, Mathew S, Krauter K, Sheinfield J, Massague J, Cardo CC. p27Ikipl: chromosomal mapping to 12p12-12p13.1 and absence of mutaions in human tumors. Cancer Res 1995;55: 1211–1214.
  • Dahia PLM, Aguiar RCT, Honegger J, Fahlbush R, Jordan S, Lowe DG, Lu X, Clayton RN, Besser GM, Grossman AB. Mutation and expression analysis of the p27Ikipl gene in corticotrophin-secreting tumors. Oncogene 1998;16:69–76.
  • Roberts J. p27Ikipl: a haploinsufficient tumor suppressor. Kidney International 1999;56:1184.
  • Montpetit A, Boily G, Sinnet D. A detailed transcriptional map of the chromosome 12p12 tumor suppressor locus. Eur J Human Genet 2002;10: 62–71.
  • Komuro H, Valentine MB, Rubnitz JE, Saito M, Raimondi JC, Carroll AJ, Yi T, Sherr CJ, Look AT. p27Ikipl deletions in childhood acute lymphoblastic leukemia. Neoplasia 1999;1: 253–261.
  • Wong KF. Genetic changes in natural killer cell neoplasms. Leukemia Res 2002;26:977–978.
  • Polyak K, Lee MH, Erdjument BH, Koff A, Roberts JM, Tempst P, Massague J. Cloning of p27Ikipl, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 1994;78: 59–66.
  • Lanier LL. NK cell receptors. Annu Rev Immunol 1998;16:359–393.
  • Philipp SJ, Payne SR, Kemp CJ. p27 (Kip 1): regulation and function of a haploinsufficient tumor suppressor and its misregulation in cancer. Exp Cell Res 2001;264: 148–168.
  • Kuroda J, Kimura S, Kobayashi Y, Jyoko N, Kamitsuji Y, Murotani Y, Fukuda W, Akaogi T, Hayashi H, Yoshikawa T, Maekawa T. Variable manifestations in natural killer cell leukemia. Clin Lab Haem 2003;25:239–245.
  • Moller MB, Skiodt K, Mortensen LS, Pedersen NT. Clinical significance of cyclin-dependent kinase inhibitor p27Kip 1 expression and proliferation in non-Hodgkin's lymphoma: independent prognostic value of p27Kip 1 . Br J Haematol 1999;105:730–736.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.