References
- Weinshilboum R M, Sladek S L. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurines methyltransferase activity. Am J Hum Genet 1980; 32: 651–662
- Yates C R, Krynetski E Y, Loennechen T, Fessing M Y, Tai H L, Pui C H, et al. Molecular diagnosis of thiopurine S-methyltrensferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. Ann Intern Med 1997; 126: 608–614
- Haglund S, Lindqvist M, Almer S, Peterson C, Taipalensuu J, et al. Pyrosequencing of TPMT alleles in a general Swedish population and in patients with inflammatory bowel disease. Clin Chem 2004; 50: 288–295
- Coulthard S A, Howell C, Robson J, Hall A G. The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia. Blood 1998; 92: 2856–2862
- McLeod H L, Krynetski E Y, Relling M V, Evans W E. Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukaemia. Leukemia 2000; 14: 567–572
- Stanulla M, Schaeffeler E, Flohr T, Cario G, Schrauder A, Zimmermann M, et al. Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia. JAMA 2005; 293: 1485–1489
- Wusk B, Kullak-Ublick G A, Rammert C, von Eckardstein A, Fried M, Rentsch K M. Thiopurine S-methyltransferase polymorphisms: efficient screening method for patients considering taking thiopurine drugs. Eur J Clin Pharmacol 2004; 60: 5–10
- Schütz E, von Ahsen N, Oellerich M. Genotyping of eight thiopurine methyltransferase mutations: ‘two-color/shared’ anchor, and fluorescence-quenching hybridization probe assays based on thermodynamic nearest-neighbour probe design. Clin Chem 2000; 46: 1728–1737