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Leukemia & Lymphoma Volume 62, 2021 - Issue 6
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Letters to the Editor

Targeted treatment of multiple myeloma with a radioiodinated small molecule radiopharmaceutical

Ankita Shahia Department of Pediatrics, School of Medicine and Public Health, Carbone Cancer Center, University of Wisconsin, Madison, WI, USAView further author information
,
Gerald E. Weissa Department of Pediatrics, School of Medicine and Public Health, Carbone Cancer Center, University of Wisconsin, Madison, WI, USAView further author information
,
Saswati Bhattacharyab Department of Medicine, Division of Hematology/Oncology, School of Medicine and Public Health, Carbone Cancer Center, University of Wisconsin, Madison, WI, USAView further author information
,
Dana C. Baiuc Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USAView further author information
,
Roberta Marinod Department of Therapeutics Production and Quality, St. Jude Children’s Research Hospital, Memphis, TN, USAView further author information
,
Taner Pulae Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, GermanyView further author information
,
Natalie S. Callanderb Department of Medicine, Division of Hematology/Oncology, School of Medicine and Public Health, Carbone Cancer Center, University of Wisconsin, Madison, WI, USAView further author information
,
Fotis Asimakopoulosb Department of Medicine, Division of Hematology/Oncology, School of Medicine and Public Health, Carbone Cancer Center, University of Wisconsin, Madison, WI, USA;f Department of Medicine, Division of Blood and Marrow Transplantation, Moores Cancer Center, University of California-San Diego, CA, USAView further author information
&
Mario Ottoa Department of Pediatrics, School of Medicine and Public Health, Carbone Cancer Center, University of Wisconsin, Madison, WI, USACorrespondence[email protected]
View further author information
 show all
Pages 1518-1521 | Received 02 Oct 2020, Accepted 04 Jan 2021, Published online: 27 Jan 2021

References

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  • Mollinedo F, de la Iglesia-Vicente J, Gajate C, et al. Lipid raft-targeted therapy in multiple myeloma. Oncogene. 2010;29(26):3748–3757.
  • Bataille R, Jego G, Robillard N, et al. The phenotype of normal, reactive and malignant plasma cells. Identification of “many and multiple myelomas” and of new targets for myeloma therapy. Haematologica. 2006;91(9):1234–1240.
  • Baiu DC, Marsh IR, Boruch AE, et al. Targeted molecular radiotherapy of pediatric solid tumors using a radioiodinated alkyl-phospholipid ether analog. J Nucl Med. 2018;59(2):244–250.
  • Lawson MA, Paton-Hough JM, Evans HR, et al. NOD/SCID-GAMMA mice are an ideal strain to assess the efficacy of therapeutic agents used in the treatment of myeloma bone disease. PloS One. 2015;10(3):e0119546.
  • Jia D, Koonce NA, Halakatti R, et al. Repression of multiple myeloma growth and preservation of bone with combined radiotherapy and anti-angiogenic agent. Radiat Res. 2010;173(6):809–817.
  • Verdonck LF, van Heugten HG. Ether lipids are effective cytotoxic drugs against multidrug-resistant acute leukemia cells and can act by the induction of apoptosis. Leuk Res. 1997;21(1):37–43.

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