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Original Articles

Estimation of the Health Risks Associated with Polychlorinated Biphenyl (PCB) Concentrations Found Onboard Older U.S. Navy Vessels

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Pages 737-758 | Published online: 30 Nov 2010

  • Agency for Toxic Substances and Disease Registry (ATSDR) . 2000 . Toxicological Profile for Polychlorinated Biphenyls , Washington, DC : Department of Health and Human Services .
  • Larcom , BJ. , Cline , J.M. Merrill , E.A. 1996 . Risk Assessment of Polychlorinated Biphenyls (PCBs) On-Board Navy Ships , NMRI96-72 OH : United States Armstrong Laboratory, Wright-Patterson AFB .
  • United States Environmental Protection Agency (U.S. EPA) . 1998 . 40 CFR Parts 7SO and 761 Disposal of Polychlorinated Biphenyls (PCBs): Final Rule . Federal Register , 63 ( 124 ) June 28
  • Hutzinger , O. , Safe , S. and Zitko , V . 1974 . The Chemistry of PCBs , Boca Raton, FL : CRC Press .
  • National Institute for Occupational Safety and Health (NIOSH) . 1992 . Recommendations for Occupational Safety and Health: Compendium of Policy Documents and Statements , DHHS (NIOSH) Publication No. 92-100 Cincinnati, OH : U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control .
  • Meigs , J.W. , Albom , JJ. and Kartin , B.L. 1954 . Cloracne from an Unusual Exposure to Aroclor . JAMA , 154 : 1417 – 1418 .
  • Ouw , H.K. , Simpson , G.R. and Siyali , D.S. 1976 . Use and Health Effects of Aroclor 1242, aPoIychlorinated Biphenyl, in an Electrical Industry . Arch Environ Health , 31 (4) : I89 – I94 .
  • Kara , I. , Harada , A. , Kimura , S. Endo , T. 1974 . Follow-Up Study of Condenser Factory After Use of PCB Discontinued (Part I) . Jap J Indus Health , 16 : 365 – 366 .
  • Kara , I. , Harada , A. , Kimura , S. , Endo , T. and Kawano , K. 1976 . FollowUp Study of Condenser Factory After Use of PCB Discontinued (Part III) . Jap J Indus Health , 17 : 371 – 372 .
  • United States Environmental Protection Agency (U.S. EPA) . 1996 . PCBs: Cancer Dose-Response Assessment and Application to Environmental Mixtures , EPA/600/P-96/001 F Washington, DC : National Center for Environmental Assessment, Office of Research and Development .
  • International Agency for Research on Cancer (IARC) . 1987 . IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans , Supplement 7 322 – 326 . Lyon, , France : World Health Organization .
  • Sinks , T. , Steele , G Smith , A.B . 1992 . Mortality Among Workers Exposed to Polychlorinated Biphenyls . Am J Epidemiol I , 36 (4) : 389 – 398 .
  • Brown , D.P. and Jones , M. 1981 . Mortality and Industrial Hygiene Study of Workers Exposed to Polychlorinated Biphenyls . Arch Environ Health , 36 : 120 – 129 .
  • Brown , D.P. 1987 . Mortality of Workers Exposed to Polychlorinated Biphenyls . An Update. Arch Environ Health , 42 (6) : 333 – 339 .
  • Bertazzi , P.A. , Riboldi , L. Pesatori , A. 1987 . Cancer Mortality of Capacitor Manufacturing Workers . Am J Indus Med , 11 : 165 – 176 .
  • Yassi , A. , Tate , R. and Fish , D. 1994 . Cancer Mortality in Workers Employed at a Transformer Manufacturing Plant . Am J Indus Med , 25 (3) : 425437
  • Maruyama , K. , Sahrul , M. Tanabe , S. 1983 . Polychlorinated Biphenyl Pollution from Shipbuilding in Nagasaki Bay, Japan . Ecotoxicol Environ Safety , 7 : 514 – 520 .
  • Hansen , L.G. 1987 . Food Chain Modification of the Composition and Toxicity of Polychlorinated Biphenyl (PCB) Residues . Rev Environ Toxicol , 3 : 149 – 212 .
  • Safe , S.H. 1994 . Polychlorinated Biphenyls (PCBs): Environmental Impact, Biochemical and Toxic Responses, and Implications for Risk Assessment . Crit Rev Toxicol , 24 : 87 – 149 .
  • Rhind , S.M. 2002 . Endocrine Disrupting Compounds and Farm Animals: Their Properties, Actions and Routes of Exposure . Dornest Anim Endocrinol , 23 : 179 – 187 .
  • Villeneuve , J.P. , Carvalho , F.P. Fowler , S.W. 1999 . Levels and Trends of PCBs, Chlorinated Pesticides and Petroleum Hydrocarbons in Mussels from the NW Mediterranean Coast: Comparison of Concentrations in 1973/1974 and 1988/1989 . Sei Total Environ , 237 ( 238 ) : 57 – 65 .
  • Donaldson , G.M. , Shutt , J.L. and Hunter , P. 1999 . Organochlorine Contamination in Bald Eagle Eggs and Nestlings from the Canadian Great Lakes . Arch Environ Contain Toxicol , 36 : 70 – 80 .
  • O'Keefe , P.W. , Silkworm , J.B. Gierthy , J.F. 1985 . Chemical and Biological Investigations of a Transformer Accident at Binghamton, NY . Environ Health Persep , 60 : 201 – 295 .
  • United States Environmental Protection Agency (U.S. EPA) . 2000 . Exposure and Human Health Reassessment of 2,3,7,8Tetrachlorodibenzo-p-Dioxin (TCDD) and Related Compounds , Washington DC : Draft. Office of Research and Development .
  • Michaud , J.M. , Huntley , S.L. Sherer , R.A. 1994 . PCB and Dioxin Re-Entry Criteria for Building Surfaces and Air . J Exposure Anal Environ Epidemiol , 4 : 197 – 227 .
  • Paustenbach , DJ. 2000 . The Practice of Exposure Assessment: A Stateof-the-Art Review . J Toxicol Environ Health, Part B , 3 : 179 – 291 .
  • Burmaster , D.E. and Andersen , P.D. 1994 . Principles for the Good Practice for the Use of Monte Carlo Techniques in Human Health and Ecological Risk Assessments . Risk Anal , 14 : 477 – 491 .
  • Burmaster , D.E. and von Stackelberg , K. 1991 . Using Monte Carlo Simulations in Public Health Risk Assessments: Estimating and Presenting Full Distributions of Risk . J Expos Anal Environ Epidemiol , 1 : 491 – 521 .
  • United States Environmental Protection Agency (U.S. EPA) . May IS 1997 . Policy for Use of Probabilistic Analysis in Risk Assessment , May IS , Washington, DC : Office of Research and Development .
  • Smith , G.C. , Hart , A.D. Rose , M.D. 2002 . Intake Estimation of Polychlorinated Dibenzo-p-Dioxins, Dibenzofurans (PCDD/Fs) and Polychlorinated Biphenyls (PCBs) in Salmon: The Inclusion of Uncertainty . Food Addit Contam , 19 (8) : 770 – 778 .
  • Vrijens , B. , De Henauw , S. Dewettinck , K. 2002 . Probabilistic Intake Assessment and Body Burden Estimation of DioxinLike Substances in Background Conditions and During a Short Food Contamination Episode . Food Addit Contam , 19 (7) : 687 – 700 .
  • Wilson , N.D. , Price , P.S. and Paustenbach , D.J. 2001 . An Event-By-Event Probabilistic Methodology for Assessing the Health Risks of Persistent Chemicals in Fish: A Case Study at the Palos Verdes Shelf . J Toxicol Environ Health Part A , 62 : 595 – 642 .
  • Adams , M.R. , Hanna , C.A. Mayernik , J.A. 1994 . Probabilistic Health Risk Assessment for Exposures to Estuary Sediments and Biota Contaminated with Polychlorinated Biphenyls, Polychlorinated Terphenyls and Other Toxic Substances . Risk Anal I , 4 (4) : 577 – 594 .
  • National Institute for Occupational Safety and Health (NIOSH) . 1994 . Manual of Analytical Methods, , 4th ed. , P&CAM 244 Cincinnati, OH : NIOSH .
  • United States Environmental Protection Agency (U.S. ERA) . 2000 . Protocol for Conducting Environmental Compliance Audits of Facilities with PCBs, Asbestos, and Lead-Based Paint Regulated under TSCA . Enforcement and Compliance Assurance (2221-A). EPA 300-B-00-004 , March
  • Occupational Safety and Health Administration (OSHA) . 1996 . OSHA Technical Manual, , 4th edition. , Houston, TX : Abs Group Inc. .
  • Hornung , R. and Reed , L. 1990 . Estimation of Average Concentration in the Presence of Non-Detectable Values . Appl Occup Environ Hyg , 5 (1) : 46 – 5 . I
  • Plog , B.A. , Niland , J. and Plog , H. 1988 . Fundamentals of Industrial Hygiene , Chicago, IL : National Safety Council .
  • United States Environmental Protection Agency (U.S. ERA) . March 2000 . Protocol for Conducting Environmental Compliance Audits of Facilities with PCBs, Asbestos, and Lead-Based Paint Regulated under TSCA, Enforcement and Compliance Assurance (2221-A) , EPA 300-B-00-004 March ,
  • Occupational Safety and Health Administration (OSHA) . 1996 . OSHA Technical Manual. , 4th edition , Houston, TX : Abs Group Inc. .
  • United States Environmental Protection Agency (U.S. EPA) . 1997 . Exposure Factors Handbook , PB98-124217 Washington, DC : USEPA .
  • United States Environmental Protection Agency (U.S. EPA) . November 4 1996 . Oral and Dermal Risk Assessment: Final; Cressona Aluminum Plant, Cressona, PA , November 4 , United States Environmental Protection Agency Region III .
  • Wester , R. , Maibach , H. Seclik , L. 1993 . Percutaneous Absorption of PCBs from Soil: In Vivo Rhesus Monkey, in Vitro Human Skin, and Binding to Powdered Human Stratum Corneum . J Toxicol Environ Health , 39 : 375 – 382 .
  • Hammerstram , K.A. February 5 1986 . Clean-Up of PCB Spills Located Indoors , February 5 , United States Environmental Protection Agency (U.S. EPA) Memorandum .
  • Michaud , J.M. , Huntley , S.L. Sherer , R.A. 1994 . PCB and Dioxin Re-Entry Criteria for Building Surfaces and Air . J Expos Anal Environ Epidemiol , 4 : 197 – 227 .
  • Flemming , C.D. , Little , O.M. and Carpenter , R.L. 1996 . Statistical Description of Physiological Variable for Seven Naval Populations , OH : Naval Medical Research Institute/Toxicology Detachment, Wright-Patterson Air Force Base .
  • United States Environmental Protection Agency (U.S. EPA) . 1989 . Assessment Guidance for Superfund: Volume I-Human Health Evaluation Manual (Part A) , EPA/540/1-89/002 Volume I ,
  • United States Environmental Protection Agency (U.S. EPA) . May 1998 . IRIS: Polychlorinated Biphenyls (PCBs); CASRN 1336-36-3 , May , Integrated Risk Information System. United States Environmental Protection Agency . www.epa.gov/iris/subst/0294.htm
  • Lloyd , RJ.W. , Moore , R.M. Woolfe , B.S. 1975 . Current Intelligence Bulletin 7: Polychlorinated Biphenyls (PCBs) , Cincinnati, OH : National Institute for Occupational Safety and Health .
  • Himes , T . 2001 . Environmental Analysis: Polychlorinated Biphenyls (PCBs): Industrial Miracle to Environmental Concern , Industrial Heating . www.industrialheating.com
  • Department of the Navy . November 2002 . Commander Military Sealift Command; Virtual Naval Hospital , November , Afloat Safety and Occupational Health Manual. Chapter 24. Polychlorinated Biphenyls . http://www.vnh. org/Admin/Afloat/Afloat24.html (Accessed
  • Mayes , B.A. , McConnell , E.E. Neal , B.H. 1998 . Comparative Carcinogenicity in Sprague-Dawley Rats of the Polychlorinated Biphenyl Mixtures Aroclors 1016, 1242,1254, and 1260 . Toxicol Sci , 41 : 62 – 76 .
  • Norback , D.H. and Weltman , R.H. 1985 . Polychlorinated Biphenyl Induction of Hepatocellular Carcinoma in the Sprague-Dawley Rat . Environ Health Perspect , 60 : 97 – 105 .
  • Schaeffer , E. , Greim , H. and Goessner , W. 1984 . Pathology of Chronic Polychlorinated Biphenyl (PCB) Feeding in Rats . Toxicol Appl Pharmacol , 75 : 278 – 288 .
  • Arnold , D.L. , Bryce , R Karpinski , K. 1993a . lexicological Consequences of Aroclor 1254 Ingestion by Female Rhesus (Macaca Mulatta) Monkeys, Part IA: Prebreeding PhaseClinical Health Findings . Food Chem Toxicol , 31 : 799 – 810 .
  • Arnold , D.L. , Bryce , F. Stapley , R. 1993b . Toxicological Consequences of Aroclor 1254 Ingestion by Female Rhesus (Macaca Mulatta) Monkeys, Part IB: Prebreeding Phase-Clinical and Analytical Laboratory Findings . Food Chem Toxicol , 31 : 811 – 824 .
  • Slayton , T.M. , Valberg , P.A. and Wait , A.D. 1998 . Estimating Dermal Transfer from PCB-Contaminated Porous Surfaces . Chemosphere , 36 : 3003 – 3014 .
  • Leung , H.-W. and Paustenbach , D.J. 1994 . Techniques for Estimating the Percutaneous Absorption of Chemicals Due to Occupational and Environmental Exposure . Appl Occup Environ Hyg , 9 : 187 – 197 .
  • Fisher , H.L. , Shah , P.V. Sumler , M.R. 1989 . In Vivo and In Vitro Dermal Penetration of 2,4,5,2',4',S'-Hexachlorobiphenyl in Young and Adult Rats . Environ Res SO , : 120 – 139 .
  • International Agency for Research on Cancer (IARC) . 1997 . IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Polychlorinated Dibenzo-para-Dioxins and Polychlorinated Dibenzofurans , Volume 69 , Lyon, , France : International Agency for Research on Cancer .
  • Kreiss , K. 1985 . Studies on Populations Exposed to PCBs . Environ Health Perspect , 60 : 193 – 199 .

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