340
Views
5
CrossRef citations to date
0
Altmetric
Brief Reports

Do non-bovine domestic animals produce A2 milk?: an in silico analysis

, , , &

References

  • FAOSTAT, FAO. http://www.fao.org/faostat/en/#data/; 2020. Accessed May 15, 2020.
  • Mei H, Sun J, Jiang ZQ, Yang YX. Effects of cow’s milk beta-casein variants on symptoms of milk intolerance in Chinese adults: a multicentre, randomised controlled study. Nutr J. 2017;16(1):1–12.
  • Jianqin S, Leiming X, Yelland GW, Ni J, Clarke JA. Effects of milk containing only A2 beta casein versus milk containing both A1 and A2 beta casein proteins on gastrointestinal physiology, symptoms of discomfort, and cognitive behavior of people with self-reported intolerance to traditional cows’ milk. Nutr J. 2016;15(35):1–16.
  • Asledottir T, Le TT, Poulsen NA, Devold TG, Larsen LB, Vegarud GE. Release of b-casomorphin-7 from bovine milk of different b-casein variants after ex vivo gastrointestinal digestion. Int Dairy J. 2018;81:8–11.
  • Brooke-Taylor S, Dwyer K, Woodford K, Kost N. Systematic review of the gastrointestinal effects of A1 compared with A2 β-casein. Adv Nutr. 2017;8(5):739–748.
  • Giglioti R, Gutmanis G, Katiki LM, Okino CH, de Sena Oliveira MC, Vercesi Filho AE. New high-sensitive rhAmp method for A1 allele detection in A2 milk samples. Food Chem. 2020;313:126167.
  • Caroli AM, Chessa S, Erhardt GJ. Invited review: milk protein polymorphisms in cattle: effect on animal breeding and human nutrition. J Dairy Sci. 2009;92(11):5335–5352.
  • Kamiński S, Ruść A, Cieślińska A. A note on frequency of A1 and A2 variants of bovine beta-casein locus in Polish Holstein bulls. J Anim Feed Sci. 2006;15(2):195–198.
  • Mishra BP, Mukesh M, Prakash B, et al. Status of milk protein, β-casein variants among Indian milch animals. Indian J Anim Sci. 2009;79(7):72–75.
  • Rahimi Z, Gholami M, Yari K. Evaluation of beta-casein locus for detection of A1 and A2 alleles frequency using allele specific PCR in native cattle of Kermanshah. Iran Biharean Biol. 2015;9(2):85–87.
  • Dai R, Fang Y, Zhao W, et al. Identification of alleles and genotypes of beta-casein with DNA sequencing analysis in Chinese Holstein cow. J Dairy Res. 2016;83(3):312–316.
  • Massella E, Piva S, Giacometti F, Liuzzo G, Zambrini AV, Serraino A. Evaluation of bovine beta casein polymorphism in two dairy farms located in northern Italy. Ital J Food Saf. 2017;6(3):131–133.
  • Rangel AH, Zaros LG, Lima TC, et al. Polymorphism in the Beta Casein Gene and analysis of milk characteristicsin Gir and Guzerá dairy cattle. Genet Mol Res. 2017;16(2):1–8.
  • Schettini GP, Lambert SM, Souza BP, Costa RB, Camargo GMF. Genetic potential of Sindhi cattle for A2 milk production. Anim Prod Sci. 2020;60(7):893–895.
  • Ramesha KP, Rao A, Basavaraju M. Genetic variants of β-casein in cattle and buffalo breeding bulls in Karnataka state of India. Indian J Biotechnol. 2016;15(2):178–181.
  • Oliveira LSM, Alves JS, Bastos MS, et al. Water buffaloes (Bubalus bubalis) only have A2A2 genotype for beta-casein. Trop Anim Health Prod. 2021;53(1):145.
  • Persuy MA, Printz C, Medrano JF, Mercier JC. A single nucleotide deletion resulting in a premature stop codon is associated with marked reduction of transcripts from a goat b-casein null allele. Anim Genet. 1999;30(6):444–451.
  • Roberts B, DiTullio P, Vitale J, Hehir K, Gordon K. Cloning of the goat β-casein-encoding gene and expression in transgenic mice. Gene. 1992;121(2):255–262.
  • Cosenza G, Pauciullo A, Colimoro L, et al. An SNP in the goat CSN2 promoter region is associated with the absence of b-casein in milk. Anim Genet. 2007;38(6):655–658.
  • Dong Y, Xie M, Jiang Y, et al. Sequencing and automated whole-genome optical mapping of the genome of a domestic goat (Capra hircus). Nat Biotechnol. 2013;31(2):135–141.
  • Provot C, Persuy MA, Mercier JC. Complete sequence of the ovine β-casein-encoding gene and interspecies comparison. Gene. 1995;154(2):259–263.
  • Provot C, Persuy MA, Mercier JC. Complete nucleotide sequence of ovine B-casein cDNA: inter-species comparison. Biochimie. 1989;71(7):827–832.
  • Kusza S, Ilie DE, Sauer M, Sauer I-W, Gavojdian D. Preliminary report on β-casein gene Met183QVal183 polymorphism in Romanian indigenous Zackel sheep breeds. Acta Biochim Pol. 2017;64(2):339–341.
  • Wade CM, Broad Institute Whole Genome Assembly Team, Giulotto E, Sigurdsson S, Zoli M, Gnerre S, Imsland F, Lear TL. Genome sequence, comparative analysis and population genetics of the domestic horse (Equus caballus). Science. 2009;326(5954):865–867.
  • Cieslak J, Wodas L, Borowska A, et al. 5’-Flanking variants of equine casein genes (CSN1S1, CSN1S2, CSN2, CSN3) and their relationship with gene expression and milk composition. J Appl Genet. 2019;60(1):71–78.
  • Brinkmann J, Jagannathan V, Drögemüller C, et al. Genetic variability of the equine casein genes. J Dairy Sci. 2016;99(7):1–12.
  • Huang J, Zhao Y, Li W. Analysis of horse genomes provides insight into the diversification and adaptive evolution of karyotype. Sci Rep. 2014;4(4958):1–7.
  • Pauciullo A, Giambra IJ, Iannuzzi L, Erhardt G. The β-casein in camels: molecular characterization of the CSN2 gene, promoter analysis and genetic variability. Gene. 2014;547(1):159–168.
  • Elbers JP, Rogers MF, Perelman PL, et al. Improving Illumina assemblies with Hi‐C and long reads: an example with the North African dromedary. Mol Ecol Resour. 2019;19(4):1015–1026.
  • Jirimutu ZW, Ding G, Chen G. Genome sequences of wild and domestic bactrian camels. Nat Commun. 2012;3(1202):1–8.
  • Richardson MF, Munyard K, Croft LJ, et al. Chromosome-level alpaca reference genome VicPac3.1 improves genomic insight into the biology of new world camelids. Front Genet. 2019;10:1–15.
  • Singh LV, Jayakumar S, Sharma A, et al. Comparative screening of single nucleotide polymorphisms in β-casein and κ-casein gene in different livestock breeds of India. Meta Gene. 2015;4:85–91.
  • Cui Y, Liu B, Qu X, Dong A, Cao A, Ma Y. Detection of β-casein variants in yak (Bos grunniens) by PCR-SSCP. Eur Food Res Technol. 2012;234(3):551–556.
  • Barni S, Sarti L, Mori F, et al. Tolerability and palatability of donkey's milk in children with cow's milk allergy. Pediatr Allergy Immunol. 2018;29(3):329–331.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.