Anti-Arthritic Activity of Hydroalcoholic Extract of Flowers of Moringa oleifera Lam. in Wistar Rats

REFERENCES

• Arend , W. P. and Dayer , J. M. 1995 . Inhibition of the production and effects of interleukin-1 and tumor necrosis factor-α in rheumatoid arthritis . Arthritis Rheum. , 38 ( 2 ) : 151 – 160 .
   PubMed Web of Science ®Google Scholar
• Arner , E. C. and Pratta , M. A. 1989 . Independent effects of interleukin-1 on proteoglycan breakdown, proteoglycan synthesis, and prostaglandin E2 release from cartilage in organ culture . Arthritis Rheum. , 32 ( 3 ) : 288 – 297 .
   PubMed Web of Science ®Google Scholar
• Bertazzolo , N. , Punzi , L. , Stefani , M. , Cesaro , G. , Pianon , M. Finco , B. 1994 . Interrelationships between interleukin IL-1, IL-6 and IL-8 in SF of various arthropathies . Inflamm. Res. , 41 ( 1–2 ) : 90 – 92 .
   Google Scholar
• Bertolini , D. R. , Nedwin , G. E. , Bringman , T. S. , Smith , D. D. and Mundy , G. R. 1986 . Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors . Nature , 319 ( 6053 ) : 516 – 518 .
   PubMed Web of Science ®Google Scholar
• Caceres , A. , Saravia , A. , Rizzo , S. , Zabala , L. , Leon , E. D. and Nave , F. 1992 . Pharmacologic properties of Moringa oleifera: 2. Screening for antispasmodic, anti-inflammatory and diuretic activity . J. Ethnopharmacol. , 36 ( 3 ) : 233 – 237 .
   PubMed Web of Science ®Google Scholar
• Caceres , A. , Cebreva , O. , Morales , O. , Miollined , P. and Mendia , P. 1991 . Pharmacological properties of M. oleifera: 1. Preliminary screening for antimicrobial activity . J. Ethnopharmacol. , 33 ( 3 ) : 213 – 216 .
   PubMed Web of Science ®Google Scholar
• Chuang , P. H. , Lee , C. W. , Chou , J. Y. , Murugan , M. , Shieh , B. J. and Chen , H. M. 2007 . Antifungal activity of crude extracts and essential oil of Moringa oleifera Lam . Biosource Technol. , 98 ( 1 ) : 232 – 236 .
   PubMed Web of Science ®Google Scholar
• Dahot , M. U. and Memon , A. R. 1985 . Nutritive significance of oil extracted from Moringa oleifera seeds . J. Pharm. (Univ. Karachi). , 3 ( 2 ) : 75 – 80 .
   Google Scholar
• Das , B. R. , Kurup , P. A. and Narasimha Rao , P. L. 1958 . Antibiotic principle from Moringa Pterosperma Part IX. Inhibition of transaminase by isocyanates . Ind. J. Med. Res. , 46 : 75 – 77 .
   PubMedGoogle Scholar
• Dayer , J. M. , Beutler , B. and Cerami , A. 1985 . Cachectinitumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts . J. Exp. Med. , 162 ( 6 ) : 2163 – 2168 .
   PubMed Web of Science ®Google Scholar
• Dayrit , F. M. , Alcantara , A. D. and Villasenor , I. M. 1990 . The antibiotic compound and its deactivation in aqueous solution . Phil. J. Sci. , 119 : 23 – 26 .
   Google Scholar
• Evans , C. H. , Robbins , P. D. , Ghivizzani , S. C. , Wasko , M. C. , Tomaino , M. M. Kang , R. 2005 . Gene transfer to human joints: Progress toward a gene 485 therapy of arthritis . Proc. Natl. Acad. Sci. U.S.A. , 102 ( 24 ) : 8698 – 8703 .
   PubMed Web of Science ®Google Scholar
• Ezeamuzie , I. C. , Ambakederemo , A. W. , Shode , F. O. and Ekwebelem , S. C. 1996 . Antiinflammatory effects of Moringa oleifera root extract . Int. J. Pharmacogn. , 34 ( 3 ) : 207 – 212 .
   Google Scholar
• Faizi , S. , Siddiqui , B. S. , Saleem , R. , Siddiqui , S. , Aftab , K. and Gilani , A. H. 1995 . Fully acetylated carbonate and hypotensive thiocarbamate glycosides from Moringa oleifera . Phytochemistry , 38 ( 4 ) : 957 – 963 .
   PubMed Web of Science ®Google Scholar
• Guevara , A. P. , Vargas , C. , Sakurai , H. , Fujiwara , Y. , Hashimoto , K. Maoka , T. 1999 . An antitumor promoter from Moringa oleifera Lam . Mutat. Res. , 440 ( 2 ) : 181 – 188 .
   PubMed Web of Science ®Google Scholar
• Halliwell , B. 1994 . Free radicals, antioxidants, and human disease: Curiosity, cause, or consequence? . Lancet. , 344 ( 8924 ) : 721 – 724 .
   PubMed Web of Science ®Google Scholar
• Hirano , T. , Matsuda , T. , Turner , M. , Miyasaka , N. , Buchan , G. B. Tang , K. 1988 . Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis . Eur. J. Immunol. , 18 ( 11 ) : 1797 – 1801 .
   PubMed Web of Science ®Google Scholar
• Hopkin , S. J. and Meager , A. 1988 . Cytokines in synovial fluid: II. The presence of tumour necrosis factor and interferon . Clin. Exp. Immunol. , 73 ( 1 ) : 88 – 92 .
   PubMed Web of Science ®Google Scholar
• Hopkins , S. J. 1990 . Cytokines and eicosanoids in rheumatic diseases . Ann. Rheum. Dis. , 49 ( 4 ) : 207 – 210 .
   PubMed Web of Science ®Google Scholar
• Husby , G. and Williams , R. C. 1988 . Synovial localization of tumor necrosis factor in patients with rheumatoid arthritis . J. Autoimmunol. , 1 ( 4 ) : 363 – 371 .
   PubMed Web of Science ®Google Scholar
• Jadhav , S. L. , Sharma , S. R , Pal , S. C. , Kasture , S. B. and Kasture , V. S. 2000 . Chemistry and pharmacology of Moringa oleifera Lam and M.concanensis Nimo . Indian Drugs , 37 ( 3 ) : 139 – 144 .
   Google Scholar
• Kamanl , A. , Naziroglu , M. , Aydilek , N. and Hacievliyagil , C. 2003 . Plasma lipid peroxidation and antioxidant levels in patients with rheumatoid arthritis . Cell Biochem. Funct. , 22 ( 1 ) : 53 – 57 .
   Web of Science ®Google Scholar
• Kasama , T. , Shiozawa , F. , Kobayashi , K. , Yajima , N. , Hanyuda , M. Takeuchi , H.T. 2001 . Vascular endothelial growth factor expression by activated synovial leukocytes in rheumatoid arthritis: Critical involvement of the interaction with synovial fibroblasts . Arthritis Rheum. , 44 ( 11 ) : 2512 – 2524 .
   PubMed Web of Science ®Google Scholar
• Kim , H. J , Krenn , V. , Steinhauser , G. and Berek , C. 1999 . Plasma cell development in synovial germinal centers patients with rheumatoid and reactive arthritis . J. Immunol. , 162 ( 5 ) : 3053 – 3062 .
   PubMed Web of Science ®Google Scholar
• Kirtikar , K. R. and Basu , B. D. 1975 . Indian Medicinal Plants , 2nd , Edited by: Dun , D. , Singh , B. and Singh , M. P. Vol. 1 , 676 – 683 . Dehradun, , India : M/s Bishen Singh Mahendra Pal Singh, New Cannaught Place .
   Google Scholar
• Koch , A. E. , Kunkel , S. L. and Strieter , R. M. 1995 . Cytokines in rheumatoid arthritis . J. Invest. Med. , 43 ( 1 ) : 28 – 38 .
   PubMed Web of Science ®Google Scholar
• Krause , I. , Valesini , G. , Scrivo , R. and Shoenfeld , Y. 2003 . Autoimmune aspects of cytokine and anticytokine therapies . Am. J. Med. , 115 ( 5 ) : 390 – 397 .
   PubMed Web of Science ®Google Scholar
• Kruithof , E. , Baeten , D. , Rycke , L. D. , Vandooren , B. , Foell , D. Roth , J. 2005 . Synovial histopathology of psoriatic arthritis, both oligo and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis . Arthritis Res. Ther. , 7 ( 3 ) : R569 – R580 .
   PubMed Web of Science ®Google Scholar
• Landrault , N. , Poucheret , P. , Ravel , P. , Gasc , F. , Cros , G. and Teissedre , P. L. 2001 . Antioxidant capacities and phenolics levels of French wines from different varieties and vintages . J. Agric. Food. Chem. , 49 ( 7 ) : 3341 – 3343 .
   PubMed Web of Science ®Google Scholar
• Mahajan , S. G , Mali , R. G. and Mehta , A. A. 2007 . Effect of Moringa oleifera Lam. seed extract on toluene diisocyanate-induced immune-mediated inflammatory responses in rats . J. Immunotoxicol. , 4 ( 2 ) : 85 – 96 .
   PubMed Web of Science ®Google Scholar
• Mahajan , S. G , Mali , R. G. and Mehta , A. A. 2007 . Protective effect of ethanolic extract of seeds of Moringa oleifera Lam. against inflammation associated with development of arthritis in rats . J. Immunotoxicol. , 4 : 39 – 47 .
   PubMed Web of Science ®Google Scholar
• Mekonnen , Y. and Gessesse , A. 1998 . Documentation on the uses of Moringa stenopetala and its possible antileishmanial and antifertility effects . SINET: Ethiopian J. Sci. , 21 ( 2 ) : 287 – 295 .
   Google Scholar
• Memon , G. M. and Khatri , L. M. 1987 . Isolation and spectroscopic studies of mono-palmitic, di-oleic triglyceride from seeds of Moringa oleifera Lam . Pak. J. Sci. Indian Res. , 30 ( 5 ) : 393 – 395 .
   Google Scholar
• Miossec , P. 1992 . Cytokine abnormalities in inflammatory arthritis . Baillieres Clin. Rheumatol. , 6 ( 2 ) : 373 – 391 .
   PubMedGoogle Scholar
• Murakami , A , Kitazono , Y. , Jiwajinda , S. , Koshimizu , K. and Ohigashi , H. 1998 . Niaziminin, a thiocarbamate from the leaves of Moringa oleifera, holds a strict structural requirement for inhibition of tumor promoter- induced Epstein-Barr virus activation . Planta Med. , 64 ( 4 ) : 319 – 323 .
   PubMed Web of Science ®Google Scholar
• Njoku , O. U. and Adikwu , M. U. 1997 . Investigation on some physicochemical antioxidant and toxicological properties of Moringa oleifera seed oil . Acta Pharm. Zagr. , 47 ( 4 ) : 287 – 290 .
   Google Scholar
• Paech , D. and Tracey , M. V. 1955 . Modern Methods of Plant Analysis , Vol. IV , 373 – 374 . Berlin : Springer-Verlag .
   Google Scholar
• Pari , L. and Kumar , N. A. 2002 . Hepatoprotective activity of Moringa oleifera on antitubercular drug-induced liver damage in rats . J. Med. Food , 5 ( 3 ) : 171 – 177 .
   PubMedGoogle Scholar
• Pearson , C. M. 1956 . Development of arthritis, periarthritis and periostitis in rats given adjuvant . Proc. Soc. Exp. Biol. Med. , 91 ( 1 ) : 95 – 101 .
   PubMedGoogle Scholar
• Pearson , C. M. and Wood , F. 1963 . Studies of arthritis and other lesions induced in rats by the injection of Mycobacterium adjuvant . Am. J. Pathol. , 42 ( 1 ) : 93 – 95 .
   Google Scholar
• Plant , M. J. , Williams , A. L. , 'Sullivan , M. M. O , Lewis , P. A. , Coles , E. C. and Jessop , J. D. 2000 . Relationship between time-integrated C-reactive protein levels and radiologic progression in patients with rheumatoid arthritis . Arthritis Rheum. , 43 ( 7 ) : 1473 – 1477 .
   PubMed Web of Science ®Google Scholar
• Ramprasath , V. R , Shanthi , P. and Sachdanandam , P. 2006 . Curative effect of Semecarpus anacardium Linn. nut milk extract against adjuvant arthritis—with special reference to bone metabolism . Chem. Biol. Interact. , 160 ( 3 ) : 183 – 192 .
   PubMed Web of Science ®Google Scholar
• Romas , E. , Gillespie , M. T. and Martin , T. J. 2002 . Involvement of receptor activator of NFkB ligand and tumor necrosis factor-∝ in bone destruction in rheumatoid arthritis . Bone , 30 ( 2 ) : 340 – 346 .
   PubMed Web of Science ®Google Scholar
• Sarban , S. , Kocyigit , A. , Yazar , M. and Isikan , U. E. 2005 . Plasma total antioxidant capacity, lipid peroxidation, and erythrocyte antioxidant enzyme activities in patients with rheumatoid arthritis and osteoarthritis . Clin. Biochem. , 38 ( 11 ) : 981 – 986 .
   PubMed Web of Science ®Google Scholar
• Schorlemmer , H. U. , Kurrle , R. , Schleyerbach , R. and Bartlett , R. R. 1999 . Disease modifying activity of malononinitrilamides, derivates of leflunomide's active metabolite, on models of rheumatoid arthritis . Inflamm. Res. , 48 ( 2 ) : 113 – 114 .
   Google Scholar
• Sugarman , B. J. , Aggarwal , B. B. , Hass , P. E. , Figari , I. S. , Palladino , M. A. and Shepard , H. M. 1985 . Recombinant human tumor necrosis factor-α: Effects on proliferation of normal and transformed cells in vitro . Science , 230 ( 4728 ) : 943 – 945 .
   PubMed Web of Science ®Google Scholar
• Udupa , S. L. , Udupa , A. L. and Kulkarni , D. R. 1994 . Studies on the anti-inflammatory and wound healing properties of Moringa oleifera and Aegle marmelos . Fitoterapia , 65 ( 2 ) : 119 – 123 .
   Google Scholar
• Vilcek , J. , Palombella , V. J. , Henriksen-DeStefano , D. , Swenson , C. , Feinman , R. Hirai , M. 1986 . Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors . J. Exp. Med. , 163 ( 3 ) : 632 – 643 .
   PubMed Web of Science ®Google Scholar
• Villasenor , I. M. , Lim-Sylianco , C. Y. and Dayrit , F. 1989 . Mutagens from roasted seeds of Moringa oleifera . Mutat. Res. , 224 ( 2 ) : 209 – 212 .
   PubMed Web of Science ®Google Scholar
• Walz , D. T. , Dimartino , J. J. and Misher , A. 1971 . Adjuvant-induced arthritis in rats: Drug effect on physiologic, biochemical and immunologic parameters . J. Pharm. Exp. Ther. , 178 ( 1 ) : 223 – 231 .
   PubMed Web of Science ®Google Scholar
• Westergren, A . 1926 . The techniques of the red cell sedimentation reaction . Am. Rev. Tuberc , 14 : 94 – 101 .
   Google Scholar
• Winter , C. A. , Risley , E. A. and Nuss , W. 1962 . Carrageenan induced edema in hind paw of rats as an assay for anti-inflammatory drugs . Proc. Soc. Exp. Biol. Med. , 111 : 544 – 547 .
   PubMed Web of Science ®Google Scholar