368
Views
10
CrossRef citations to date
0
Altmetric
Articles

Thymoquinone protection against 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin induced nephrotoxicity in rats

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon &

References

  • Aebi HI, Bergmayer H. 1974. Methods of enzymatic analysis. London: Academic Press; p. 673–677.
  • Al-Rasheed N, Faddah LM, Hasan IH, Ali HM, Al-Rasheed N, El Oraby NF, Mohamed MH. 2017. Amelioration of panadol-induced nephrotoxicity via down-regulation of Bax/Bcl2 ratio with some antioxidants. Pharmacol Rep. 69:1088–1093. doi:10.1016/j.pharep.2017.04.019.
  • Alsharif NZ, Hassoun EA. 2004. Protective effects of vitamin A and vitamin E succinate against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced body wasting, hepatomegaly, thymic atrophy, production of reactive oxygen species and DNA damage in C57BL/6J mice. Basic Clin Pharmacol Toxicol. 95:131–138. doi:10.1111/j.1742-7843.2004.950305.x.
  • Arslan SO, Gelir E, Armutcu F, Coskun O, Gurel A, Sayan H, Çelik IL. 2005. The protective effect of thymoquinone on ethanol induced acute gastric damage in the rat. Nutr Res. 25:673–680. doi:10.1016/j.nutres.2005.06.004.
  • Aycan İÖ, Elpek Ö, Akkaya B, Kıraç E, Tuzcu H, Kaya S, Çoşkunfırat N, Aslan M. 2018. Diclofenac induced gastrointestinal and renal toxicity is alleviated by thymoquinone treatment. Food Chem Toxicol. 118:795–804. doi:10.1016/j.fct.2018.06.038.
  • Aydin O, Akyuz F, Tekin N, Ustuner M, Degirmenci I, Burukoglu D, Ozden H. 2016. Effect of retinyl acetate on transglutaminase 2 activity in carcinogen treated rat liver. Biotech Histochem. 5:342–351.
  • Badary OA. 1999. Thymoquinone attenuates ifosfamide-induced Fanconi syndrome in rats and enhances its antitumor activity in mice. J Ethnopharmacol. 67:135–142. doi:10.1016/S0378-8741(98)00242-6.
  • Bancroft JD, Gamble M, Eds. 2002. Theory and practice of histological techniques. 5th ed. London: Churchill Livingstone; p. 173–185.
  • Carden DL, Granger DN. 2000. Pathophysiology of ischemia-reperfusion injury. J Pathol. 190:255–266. doi:10.1002/(SICI)1096-9896(200002)190:3<255::AID-PATH526>3.0.CO;2-6.
  • Chan CYY, Kim CP, Winn LM. 2004. TCDD-induced homologous recombination: the role of the Ah receptor versus oxidative DNA damage. Mutat Res. 563:71–79. doi:10.1016/j.mrgentox.2004.05.015.
  • Ciftci O, Ozdemir I, Vardi N, Beytur A, Oguz A. 2012. Ameliorating effects of quercetin and chrysin on 2,3,7,8 tetrachlorodibenzo-p-dioxin-induced nephrotoxicity in rats. Toxicol Ind Health. 10:947–954. doi:10.1177/0748233711430978.
  • Darakhshan S, Pour AB, Colagar AH, Sisakhtnezhad S. 2015. Thymoquinone and its therapeutic potentials. Pharmacol Res. 95:138–158. doi:10.1016/j.phrs.2015.03.011.
  • Dömötörova M, Stachova Sejakova Z, Kocan A, Conka K, Chovancova J, Fabisikova A. 2012. PCDDs, PCDFs, dioxin-like PCBs and indicator PCBs in soil from five selected areas in Slovakia. Chemosphere. 89:480–485. doi:10.1016/j.chemosphere.2012.05.106.
  • Ellman GL. 1979. Tissue sulphydryl groups. Arch Biochem Biophys. 95:351–358.
  • Erdemli ME, Yigitcan B, Gul M, Bag HG, Gul S, Aksungur Z. 2018. Thymoquinone is protective against 2,3,7,8-tetrachlorodibenzo-p-dioxin induced hepatotoxicity. Biotech Histochem. 6:453–462. doi:10.1080/10520295.2018.1453549.
  • Erel O. 2004. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem. 37:277–285. doi:10.1016/j.clinbiochem.2003.11.015.
  • Erel O. 2005. A new automated colorimetric method for measuring total oxidant status. Clin Biochem. 38:1103–1111. doi:10.1016/j.clinbiochem.2005.08.008.
  • Ferdous AJ, Islam SN, Ashan M, Hasan CM, Ahmed ZU. 1992. In vitro antibacterial activity of the volatile oil of Nigella sativa seeds against multiple drug resistant isolates of Shigella, V. Cholerae and E. Coli. Phytother Res. 6:137–140. doi:10.1002/ptr.2650060307.
  • Hassoun EA, Li F, Abushaban A, Stohs SJ. 2000. The relative abilities of TCDD and its congeners to induce oxidative stress in the hepatic and brain tissues of rats after subchronic exposure. Toxicology. 145:103–113. doi:10.1016/S0300-483X(99)00221-8.
  • Havakhah S, Sadeghnia HR, Mosa-Al-Reza Hajzadeh NM, Roshan SS, Hosseinzadeh H, Mohareri N, Rad K. 2014. Effect of Nigella sativa on ischemia-reperfusion induced rat kidney damage. Iran J Basic Med Sci. 17:986–992.
  • Hites RA. 2011. Dioxins: an overview and history. Environ Sci Technol. 1:16–20. doi:10.1021/es1013664.
  • Hoover RN. 1999. Dioxin dilemmas. J Natl Cancer Inst. 9:745–746. doi:10.1093/jnci/91.9.745.
  • Hossain A, Tsuchiya S, Minegishi M, Osada M, Ikawa S, Tezuka FA, Kaji M, Konno T, Watanabe M, Kikuchi H. 1998. The Ah receptor is not involved in 2,3,7,8 tetrachlorodibenzo- p-dioxin-mediated apoptosis in human leukemic 416T cell lines. J Biol Chem. 273:19853–19858. doi:10.1074/jbc.273.31.19853.
  • Hosseini SM, Taghiabadi E, Abnous K, Hariri AT, Pourbakhsh H, Hosseinzade H. 2017. Protective effect of thymoquinone, the active constituent of Nigella sativa fixed oil, against ethanol toxicity in rat. Iran J Basic Med Sci. 20:927–939. doi:10.22038/IJBMS.2017.9116.
  • Hosseınzadeh H, Parvardeh S. 2004. Anticonvulsant effects of thymoquinone, the majör constituent of Nigella sativa seeds, in mice. Phytomedicine. 11:56–64. doi:10.1078/0944-7113-00376.
  • Hu K, Bunce NJ. 1999. Metabolism of polychlorinated dibenzo-p-dioxins and related dioxin-like compounds. J Toxicol Environ Health B Crit Rev. 2:183–210. doi:10.1080/109374099281214.
  • Iida T, Hirakawa H, Matsueda T, Nagayama J, Nagata T. 1999. Polychlorinated dibenzo-p-dioxins and related compounds: correlations of levels in human tissues and in blood. Chemosphere. 12:2767–2774. doi:10.1016/S0045-6535(98)00478-0.
  • Jolitha AB, Subramanyam MV, Devi SA. 2006. Modification by vitamin E and exercise of oxidative stress in regions of aging rat brain: studies on superoxide dismutase isoenzymes and protein oxidation status. Exp Gerontol. 41:753–763. doi:10.1016/j.exger.2006.04.007.
  • Jonosek J, Hilscherova K, Blaha L, Holoubek I. 2005. Environmental xenobiotics and nuclear receptors-inter-actions, effects and in vitro assessment. Toxicol In Vitro. 20:18–37. doi:10.1016/j.tiv.2005.06.001.
  • Kaseb AO, Chınnakannu K, Chen D, Sıvanandam A, Tejwanı S, Menon M, Dou QP, Reddy GP. 2007. Androgen receptor and e2f-1 targeted thymoquinone therapy for hormone-refractory prostate cancer. Cancer Res. 67:7782–7788. doi:10.1158/0008-5472.CAN-07-1483.
  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the folin phenol reagent. J Biol Chem. 193:265–275.
  • Mahiout S, Lindén J, Esteban J, Sánchez-Pérez I, Sankari S, Pettersson L, Håkansson H, Pohjanvirta R. 2017. Toxicological characterisation of two novel selective aryl hydrocarbon receptor modulators in Sprague-Dawley rats. Toxicol Appl Pharmacol. 326:54–65. doi:10.1016/j.taap.2017.04.020.
  • Mollazadeh H, Hosseinzadeh H. 2014. The protective effect of Nigella sativa against liver injury: a review. Iran J Basic Med Sci. 17:958–966.
  • Ozer EK, Goktas MT, Toker A, Pehlivan S, Bariskaner H, Ugurluoglu C, Iskit AB. 2017. Thymoquinone protects against the sepsis induced mortality, mesenteric hypoperfusion, aortic dysfunction and multiple organ damage in rats. Pharmacol Rep. 69:683–690. doi:10.1016/j.pharep.2017.02.021.
  • Parzefall W. 2002. Risk assesstment of dioxins contamination in human food. Food Chem Toxicol. 40:1185–1189. doi:10.1016/S0278-6915(02)00059-5.
  • Pirkle JL, Wolfe WH, Patterson DG, Needham LL, Michalek JE, Miner JS. 1989. Estimates of the half-life of 2, 3, 7, 8-TCDD in Vietnam veterans of operation ranch hand. J Toxicol Environ Health. 27:165–171. doi:10.1080/15287398909531288.
  • Pohjanvirta R, Vartiainen T, Uusi-Rauva A, Monkkonen J, Tuomisto J. 1990. Tissue distribution, metabolism, and excretion of 14C-TCDD in a TCDD-susceptible and a TCDD-resistant rat strain. Pharmacol Toxicol. 66:93–100. doi:10.1111/j.1600-0773.1990.tb00712.x.
  • Pohjanvirta R, Tuomisto J. 1994. Short-term toxicity of 2,3,7,8 tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms and animal models. Pharmacol Rev. 46:483–549.
  • Riddick DS, Lee C, Bhathena A, Timsit YE, Cheng PY, Morgan ET, Prough RA, Ripp SL, Miller KK, Jahan A, Chiang JY. 2004. Transcriptional suppression of cytochrome P-450 genes by endogeneous and exogeneous chemicals. Drug Metab Dispos. 67:323–375.
  • Salem ML. 2005. Immunomodulatory and immunotherapeutic properties of the Nigella sativa L. Seed Int Imunopharmacol. 5:1749–1770. doi:10.1016/j.intimp.2005.06.008.
  • Schecter A, Birnbaum L, Ryan JJ, Constable JD. 2006. Dioxins: an overview. Environ Res. 101:419–428. doi:10.1016/j.envres.2005.12.003.
  • Serafini M, Del Rio D. 2004. Understanding the association between dietary antioxidants, redox status and disease: is the total antioxidant capacity the right tool? Redox Rep. 9:145–152. doi:10.1179/135100004225004814.
  • Uchiyama M, Mihara M. 1978. Determination of MDA precursor in tissue by TBA test. Anal Biochem. 36:271–278. doi:10.1016/0003-2697(78)90342-1.
  • Urso ML, Clarkson PM. 2003. Oxidative stress, exercise, and antioxidant supplementation. Toxicology. 189:41–54. doi:10.1016/S0300-483X(03)00151-3.
  • van der Ven LTM, van de Kuil T, Leonards PEG, Slob W, Lilienthal H, Litens S, Herlin M, Håkansson H, Cantón RF, van den Berg M, Visser TJ, van Loveren H, Vos JG, Piersma AH. 2009. Endocrine effects of hexabromocyclododecane (HBCD) in a one-generation reproduction study in Wistar rats. Toxicol Lett. 185:51–62. doi:10.1016/j.toxlet.2008.12.003.
  • Watanabe S, Kitamura K, Nagahashi M. 1999. Effects of dioxins on human health: a review. J Epidemiol. 1:1–13. doi:10.2188/jea.9.1.
  • Yeum KJ, Russell MR, Krinsky IN, Adlini G. 2004. Biomarkers of antioxidan capacity in hydrophilic and lipophilic compartments of human plasma. Arch Biochem Biophys. 430:97–103. doi:10.1016/j.abb.2004.03.006.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.