An improved method for estimating antibody titers in microneutralization assay using green fluorescent protein

References

• Baker, S. F., Guo, H., Albrecht, R. A., Garca-Sastre, A., Topham, D. J., Martnez-Sobrido, L. (2013). Protection against lethal influenza with a viral mimic. Journal of Virology 87:8591–8605.
   PubMed Web of Science ®Google Scholar
• Baker, S. F., Nogales, A., Finch, C., Tuffy, K. M., Domm, W., Perez, D. R., Topham, D. J., Martnez-Sobrido, L. (2014). Influenza A and B virus intertypic reassortment through compatible viral packaging signals. Journal of Virology 88: 10778–10791.
   PubMed Web of Science ®Google Scholar
• Belanger, B. A., Davidian, M., Giltinan, D. M. (1996). The effect of variance function estimation on nonlinear calibration inference in immunoassay data. Biometrics 52:158–175.
   PubMed Web of Science ®Google Scholar
• Biacchesi, S., Skiadopoulos, M. H., Yang, L., Murphy, B. R., Collins, P. L., Buchholz, U. J. (2005). Rapid human metapneumovirus microneutralization assay based on green fluorescent protein expression. Journal of Virology Methods 128:192–197.
   PubMed Web of Science ®Google Scholar
• Carroll, R. J., Ruppert, D. (1988). Transformation and Weighting in Regression. New York: Chapman and Hall.
   Google Scholar
• Caton, A. J., Brownlee, G. G., Yewdell, J. W., Gerhard, W. (1982). The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype). Cell 31:417–27.
   PubMed Web of Science ®Google Scholar
• Combita, A., Touze, A., Bousarghin, L., Christensen, N. D., Coursaget, P. (2002). Identification of two cross-neutralizing linear epitopes within the L1 major capsid protein of human papillomaviruses. Journal of Virology 76:6480–6486.
   PubMed Web of Science ®Google Scholar
• Davidian, M., Carroll, R. J., Smith, W. (1988). Variance functions and the minimum detectable concentration in assays. Biometrika 75:549–556.
   Web of Science ®Google Scholar
• Domm, W., Brewer, M., Baker, S. F., Feng, C., Martnez-Sobrido, L., Treanor, J., Dewhurst, S. (2014). Use of bacteriophage particles displaying influenza virus hemagglutinin for the detection of hemagglutination-inhibition antibodies. Journal of Virology Methods 197:47–50.
   PubMed Web of Science ®Google Scholar
• Dowdle, W. N., Kendal, A. P., Noble, G. R. (1979). Influenza viruses. In Diagnostic procedures for Viral, Rickettsial and Chlamydial Infections, 5th Ed. (pp. 603–605). Washington, DC: American Public Health Association.
   Google Scholar
• Feng, F., Sales, A. P., Kepler, T. B. (2011). A Bayesian approach for estimating calibration curves and unknown concentrations in immunoassays. Bioinformatics 27:707–712.
   PubMed Web of Science ®Google Scholar
• Finney, D. J. (1976). Radioligand assay. Biometrics 32:721–740.
   PubMed Web of Science ®Google Scholar
• Guo, H., Baker, S. F., Martnez-Sobrido, L., Topham, D. J. (1998). Induction of CD8 T Cell heterologous Protection by a single dose of single-cycle infectious influenza virus. Journal of Virology pii: JVI.01847-14.
   Google Scholar
• Healy, M. J. R. (1972). Statistical analysis of radioimmunoassay data. Biochemistry Journal 130:207–210.
   PubMed Web of Science ®Google Scholar
• Higgins, K. M., Davidian, M., Chew, G., Burge, H. (1998). The effect of serial dilution error on calibration inference in immunoassay. Biometrics 54:19–32.
   PubMed Web of Science ®Google Scholar
• Killian, M. L. (2008). Hemagglutination assay for the avian influenza virus. Methods in Molecular Biology 436:47–52.
   PubMedGoogle Scholar
• Lam, R., Farrell, R., Aziz, T., Gibbs, E., Giovannoni, G., Grossberg, S., Oger, J. (2008). Validating parameters of a luciferase reporter gene assay to measure neutralizing antibodies to IFNbeta in multiple sclerosis patients. Journal of Immunological Methods 336:113–118.
   PubMed Web of Science ®Google Scholar
• Martinez-Sobrido, L., Cadagan, R., Steel, J., Basler, C. F., Palese, P., Moran, T. M., Garcia-Sastre, A. (2010). Hemagglutinin-pseudotyped green fluorescent protein-expressing influenza viruses for the detection of influenza virus neutralizing antibodies. Journal of Virology 84:2157–2163.
   PubMed Web of Science ®Google Scholar
• Montefiori, D. C. (2005). Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays. Current Protocols in Immunology Chapter 12, Unit 12.11.
   PubMedGoogle Scholar
• Okuma, K., Nakamura, M., Nakano, S., Niho, Y., Matsuura, Y. (1999). Host range of human T-cell leukemia virus type I analyzed by a cell fusion-dependent reporter gene activation assay. Virology 254:235–244.
   PubMed Web of Science ®Google Scholar
• Paul, G., Gottschalk, J. R. D. (2005). The five-parameter logistic: A characterization and comparison with the four-parameter logistic. Analytical Biochemistry 343:54–65.
   PubMed Web of Science ®Google Scholar
• Reed, L. J., Muench, H. (1938). A simple method of estimating fifty percent endpoints. American Journal of Epidemiology 27:493–497.
   Google Scholar
• Rimmelzwaan, G. F., Verburgh, R. J., Nieuwkoop, N. J., Bestebroer, T. M., Fouchier, R. A., Osterhaus, A. D. (2011). Use of GFP-expressing influenza viruses for the detection of influenza virus A/H5N1 neutralizing antibodies. Vaccine 18:3424–3430.
   Web of Science ®Google Scholar
• Rodbard, D. (1978). Statistical estimation of the minimal detectable concentration (Sensitivity) for radioligand assay. Analytical Biochemistry 90:1–12.
   PubMed Web of Science ®Google Scholar
• Rodbard, D., Frazier, G. R. (1975). Statistical analysis of radioligand assay data. Methods of Enzymology 37:839–841.
   Google Scholar
• Sprangers, M. C., Lakhai, W., Koudstaal, W., Verhoeven, M., Koel, B. F., Vogels, R., Goudsmit, J., Havenga, M. J. E., Kostense, S. (2003). Quantifying adenovirus-neutralizing antibodies by luciferase transgene detection: Addressing preexisting immunity to vaccine and gene therapy vectors. Journal of Clinical Microbiology 41:5046–5052.
   PubMed Web of Science ®Google Scholar
• Wang, D, Soong, S. J. (2008). Comparisons of titer estimation methods for multiplexed pneunococcal opsonophagocytic killing assay. Computational Statistics and Data Analysis 52:5022–5032.
   Web of Science ®Google Scholar
• Wiley, D. C., Wilson, I. A., Skehel, J. J. (1981). Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation. Nature 289:373–378.
   PubMed Web of Science ®Google Scholar
• Wrammert, J., Koutsonanos, D., Li, G. M., Edupuganti, S., Sui, J., Morrissey, M., McCausland, M., Skountzou, I., Hornig, M., Lipkin, W. I., Mehta, A., Razavi, B., Del Rio, C., Zheng, N. Y., Lee, J. H., Huang, M., Ali, Z., Kaur, K., Andrews, S., Amara, R. R., Wang, Y., Das, S. R., O’Donnell, C. D., Yewdell, J. W., Subbarao, K., Marasco, W. A., Mulligan, M. J., Compans, R., Ahmed, R., Wilson, P. C. (2011). Broadly cross-reactive antibodies dominate the human B cell response against 2011 pandemic H1N1 influenza virus infection. Journal of Experimental Medicine 208:181–93.
   PubMed Web of Science ®Google Scholar
• Zeng, Q., Davidian, M. (1997). Bootstrap-adjusted calibration confidence intervals for Immunoassay. Journal of the American Statistical Association 92:278–290.
   Web of Science ®Google Scholar