Advanced search
Publication Cover
Journal of Addictive Diseases Volume 38, 2020 - Issue 2
Submit an article Journal homepage
177
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Haloperidol for the treatment of opioid addiction in advanced cancer patients: a case series

Alessandro ParisiMedical Oncology, St. Salvatore Hospital, University of L’Aquila, L’Aquila, Italy; ;Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, ItalyCorrespondence[email protected]
, MD,
Maria Vittoria PensieriMedical Oncology, St. Salvatore Hospital, University of L’Aquila, L’Aquila, Italy; ;Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
, MD,
Alessio CortelliniMedical Oncology, St. Salvatore Hospital, University of L’Aquila, L’Aquila, Italy; ;Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
, MD,
Carla D’OrazioMedical Oncology, St. Salvatore Hospital, University of L’Aquila, L’Aquila, Italy; ;Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
, MD,
Corrado FicorellaMedical Oncology, St. Salvatore Hospital, University of L’Aquila, L’Aquila, Italy; ;Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
, MD,
Lucilla VernaMedical Oncology, St. Salvatore Hospital, University of L’Aquila, L’Aquila, Italy; ;Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
, MD &
Giampiero PorzioMedical Oncology, St. Salvatore Hospital, University of L’Aquila, L’Aquila, Italy; ;Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy
, MD show all
Pages 229-234 | Published online: 24 Mar 2020

References

  • Arthur JA, Haider A, Edwards T, Waletich-Flemming J, Reddy S, Bruera E, Hui D. Aberrant opioid use and urine drug testing in outpatient palliative care. J Palliat Med. 2016;19(7):778–82. doi:10.1089/jpm.2015.0335.
  • Hojsted J, Sjogren P. Addiction to opioids in chronic pain patients: a literature review. Eur J Pain. 2007;11:490–518.
  • Heit HA. Addiction, physical dependence, and tolerance: precise definitions to help clinicians evaluate and treat chronic pain patients. J Pain Palliat Care Pharmacother. 2003;17(1):15–29. doi:10.1080/J354v17n01_03.
  • Martinez D, Saccone PA, Liu F, et al. Deficits in dopamine D(2) receptors and presynaptic dopamine in heroin dependence: commonalities and differences with other types. Biol Psychiatry. 2012 Feb 1;71(3):192–8. doi: 10.1016/j.biopsych.2011.08.024.
  • Tyler MW, Zaldivar-Diez J, Haggarty SJ. Classics in chemical neuroscience: haloperidol. ACS Chem Neurosci. 2017;8(3):444–53. Mar 15 Epub 2017 Feb 15. doi:10.1021/acschemneuro.7b00018.
  • Yang C, Chen Y, Tang L, Wang ZJ. Haloperidol disrupts opioid-antinociceptive tolerance and physical dependence. J Pharmacol Exp Ther. 2011;338(1):164–72. Jul Epub 2011 Mar 24. doi:10.1124/jpet.110.175539.
  • Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–70. doi:10.1111/j.1600-0447.1983.tb09716.x.
  • Mancini M, Perna G, Rossi A, Petralia A. Use of duloxetine in patients with an anxiety disorder, or with comorbid anxiety and major depressive disorder: a review of the literature. Expert Opin Pharmacother. 2010;11(7):1167–81. doi:10.1517/14656561003747441.
  • Gaynor PJ, Gopal M, Zheng W, Martinez JM, Robinson MJ, Marangell LB. A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms. Curr Med Res Opin. 2011;27(10):1849–58. doi:10.1185/03007995.2011.609539.
  • Mayfield D, McLeod G, Hall P. The CAGE questionnaire: validation of a new alcoholism screening instrument. Am J Psychiatry. 1974;131:1121–3.
  • Wu SM, Compton P, Bolus R, Schieffer B, Pham Q, Baria A, Van Vort W, Davis F, Shekelle P, Naliboff BD, et al. The addiction behaviors checklist: validation of a new clinician-based measure of inappropriate opioid use in chronic pain. J Pain Symptom Manage. 2006;32(4):342–51. doi:10.1016/j.jpainsymman.2006.05.010.
  • Ballantyne JC. Chronic pain following treatment for cancer: the role of opioids. Oncologist. 2003;8(6):567–75. edoi:10.1634/theoncologist.8-6-567.
  • Carmichael AN, Morgan L, Fabbro D. E. Identifying and assessing the risk of opioid abuse in patients with cancer: an integrative review. Subst Abuse Rehabil. 2016;7:71–9.
  • Kim YJ, Dev R, Reddy A, Hui D, Tanco K, Park M, Liu D, Williams J, Bruera E. Association between tobacco use, symptom expression, and alcohol and illicit drug use in advanced cancer patients. J Pain Symptom Manage. 2016;51(4):762–8. doi:10.1016/j.jpainsymman.2015.11.012.
  • Strasser F, Walker P, Bruera E. Palliative pain management: when both pain and suffering hurt. J Palliat Care. 2005;21(2):69–79. doi:10.1177/082585970502100202.
  • Kalivas PW, O'Brien C. Drug addiction as a pathology of staged neuroplasticity. Neuropsychopharmacol. 2008;33(1):166–80. doi:10.1038/sj.npp.1301564.
  • Menon V, Levitin DJ. The rewards of music listening: Response and physiological connectivity of the mesolimbic system. Neuroimage. 2005;28(1):175–84. doi:10.1016/j.neuroimage.2005.05.053.
  • Kreek MJ, Reed B, Butelman ER. Current status of opioid addiction treatment and related preclinical research. Sci Adv. 2019;5(10):eaax9140. Oct 2 eCollection 2019 Oct. Review. doi:10.1126/sciadv.aax9140.
  • Afzalimoghaddam M, Edalatifard M, Nejati A, Momeni M, Isavi N, Karimialavijeh E. Midazolam plus haloperidol as adjuvant analgesics to morphine in opium dependent patients: a randomized clinical trial. Curr Drug Abuse Rev. 2017;9(2):142–7. doi:10.2174/1874473710666170106122455.
  • Go SI, Song HN, Lee SJ, Bruera E, Kang JH. Craving behavior from opioid addiction controlled with olanzapine in an advanced cancer patient: a case report. J Palliat Med. 2018;21(9):1367–70. Sep Epub 2018 Aug 2. doi:10.1089/jpm.2017.0636.
  • Riley DS, Barber MS, Kienle GS, AronsonJK v, Schoen-Angerer T, Tugwell P, Kiene H, Helfand M, Altman DG, Sox H, Werthmann PG, Moher D, et al. CARE guidelines for case reports: explanation and elaboration document. J Clin Epidemiol. 2017;89:S0895-4356(17)30037-9. doi:10.1016/j.jclinepi.2017.04.026.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.