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Original Articles

Lipophilic ditopic guanidinium receptors: selective extractants for tetrahedral oxoanions

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Pages 273-280 | Received 05 Dec 1994, Published online: 23 Sep 2006

References

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  • Schieβl , P. and Schmidtchen , F. P. submitted.
  • The conversion of the OH group into a methoxy or ethoxy function should overcome these problems.
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  • A 1:1 complex formation (anion : receptor) gives a stoichiometric coefficient s = 1, and 1:2 complex formation s = 2, respectively.
  • In most cases the pH value were adjusted by buffer solutions (TAPS, HEPES) in order to guarantee a constant species distribution of the anions.
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  • Extraction experiments using a quaternary ammonium salt (Aliquat 336) support this assumption. Aliquat 336 extracts traces of sulfate, whereas hydrogen phosphate is not transfered into the organic phase.
  • Under the experimental conditions chosen there is no detectable dephosphorilation of the nucleotides. The distribution ratios are constant in a 2 h extraction period.
  • At the pH of 8.7 compound 2, (creceptor = 1·10−3 M in chloroform) extracts 1% TAPS (cTAPS(W) = 5·10−2 M). Thus. the concentration of TAPS in chloroform is 5·10−4 M, and consequently 50% of the receptor is complexed by the buffer. At the pH of 7.8 only 0.33 % TAPS was transferred into chloroform (17 % of 2, is loaded with TAPS). TAPS was not extracted in the absence of the anion receptor 2.
  • Perrin , D. D. 1978 . “ Stability Constants of Metal-ion Complexes-Part B-Organic Ligands ” . Oxford-New York-Toronto-Sydney-Paris-Frankfurt : Pergamon Press .
  • The deviation from the slope of 1 is significant in the high concentration range. To verify the shape of the curves obtained three independent experimental cycles were performed.
  • Smith , R. M. , Martell , A. E. and Chen , Y. 1991 . Pure Appl. Chem. , 63 : 1015

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