80
Views
69
CrossRef citations to date
0
Altmetric
Research Article

Harmine: Evaluation of its Antileishmanial Properties in Various Vesicular Delivery Systems

, , , &
Pages 165-175 | Received 14 Jan 2004, Accepted 27 Feb 2004, Published online: 03 Oct 2008

References

  • Abe, F., NagaFuji, S., Yamauchi, T., Okabe, H., Maki, J., Higo, H., Akahane, H., Aguilar, A., Jimenez-Estrada, M. and Reyes-Chilpa, R. (2002) “Trypanocidal constituents in plants 1. Evaluation of some Mexican plants for their trypanocidal activity and active constituents in Guaco, roots of Aristolochia taliscana”, Biol. Pharm Bull. 25(9), 1188– 1197.
  • Airaksinen, M.M. and Kari, I. (1981) “Beta-carbolines, psychoactive compounds in the mammalian body. Part II. Effects”, Med. Biol. 59(4),190–211.
  • Baillie, A.J., Florence, A.T., Hume, L.R., Muirhead, G.T. and Rogerson, A. (1985) “The preparation and properties of niosome - non-ionic surfactant vesicles”, J. Phar. Pharmacol. 37(12),863–868.
  • Bessey, O.A., Lowry, O.H. and Brock, M. (1946) “A method for rapid determination of alkaline phosphatase with five cubic millimetres of serum”, J. Biol. Chem. 164, 321–329, Cited in: Bergmeyer, H.Y., ed, Methods of Enzymatic Analysis, 2nd Edition, (Academic Press, New York), Vol. 1, pp. 856–864.
  • Boeira, J.M., da Silva, J., Erdtmann, B. and Henriques, J.A. (2001) “Genotoxic effects of the alkaloids harman and harmine assessed by comet assay and chromosome aberration test in mammalian cells in vitro”, Pharmacol. Toxicol. 89(6),287–294.
  • Boeira, J.M., Viana, A.F., Picada, J.N. and Henriques, J.A. (2002) “Genotoxic and recombinogenic activities of the two beta-carboline alkaloids harman and harmine in Saccharomyces cerevisiae”, Mutat. Res. 500(1-2), 39–48.
  • Cui, Z. and Mumper, R.J. (2003) “Microparticles and nanoparticles as delivery systems for DNA vaccines”, Crit. Rev. Ther. Drug Carrier Syst. 20(2-3), 103–137.
  • Das, N., Mahato, S.B., Naskar, K., Ghosh, B.K. and Basu, M.K. (1990) “Targeting of urea stibamine encapsulated in liposomes to reticuloendothelial system for the treatment of experimental leishmaniasis”, Biochem. Med. Metab. Biol. 43, 133–139.
  • Gregoriadis, G. and Ryman, B.E. (1972) “Lysosomal localisation of b-fructofuranosidase containing liposomes injected into rats”, Biochem. J. 12, 1020–1030.
  • Gurr, E. (1962) Staining Animal Tissues: Practical and Theoretical (Leonard Hill, London, United Kingdom).
  • Guterres, S.S., Fessi, H., Barratt, G., Devissaguet, J.P. and Puisieux, F. (1995) “Poly(DL-Lactide) nanocapsules containing diclofenac I. Formulation and stability study”, Int. J. Pharm. 113, 57–63.
  • Ishida, J., Wang, H.K., Bastow, K.F., Hu, C.Q. and Lee, K.H. (1999) “Antitumor agents 201. Cytotoxicity of harmine and beta-cartboline analogs”, Bioorg. Med. Chem. Lett. 9(23),3319–3324.
  • Ishida, J., Wang, H.K., Oyama, M., Cosentino, M.L., Hu, C.Q. and Lee, K.H. (2001) “Anti-AIDS agents 46. Anti-HIV activity of harman, an anti-HIV principle from Symplocos setchuensis, and its derivatives”, J. Nat. Prod. 64(7),958–960.
  • Kreuter, J. (1996) “Nanoparticles and microparticles for drug and vaccine delivery”, J. Anat. 189(Pt 3), 503–505.
  • Lala, S., Nandy, A.K., Mahato, S.B. and Basu, M.K. (2003) “Delivery in vivo of 14-deoxy-11-oxoandrographolide, an antileishmanial agent, by different drug carriers”, Indian J. Biochem. Biophys. 40, 169–174.
  • Looker, D.L., Bereus, R.L. and Marr, J.J. (1983) “Purine metabolism in Leishmania donovani amastigotes and promastigotes”, Mol. Bio- Chem. Parasitol. 19, 15–28.
  • Ma, Z.Z., Hano, Y., Nomura, T. and Chen, Y.J. (2000) “Alkaloids and phenylpropanoids, from Peganum nigellastrum”, Phytochemistry 53(8),1075–1078.
  • Martin, B.S., Reutelingsperger, C.P., McGahon, A.J., Van Schiee, R.C.A.A., La Face, D.M. and Greenn, D.R. (1995) “Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of initiating stimulus inhibition by over expression of Bcl 2 and Abl”, J. Exp. Med. 182, 1345–1350.
  • Molero, M.L., Hazen, M.J., Perez-Gorrono, A.I. and Stockert, J.C. (1995) “Simple beta-carboline alkaloids as nucleic acid fluorochromes”, Acta Histochem. 97(2),165–173.
  • Mukhopadhyay, S., Banerjee, S.K., Atal, C.K., Lin, L.-J. and Cordell, G.A. (1987) “Alkaloids of Corydalis govaniana”, J. Nat. Prod. 50, 270–273. Panyam, J. and Labhasetwar, V. (2003) “Biodegradable nanoparticles for drug and gene delivery to cells and tissues”, Adv. Drugs Deliv. Rev. 55(3),329–347.
  • Quintanar-Guerrero, D., Allemann, E., Fessi, H. and Doelker, E. (1998) “Preparation, techniques and mechanism of formation of biodegrad- able nanoparticles from preformed polymers”, Drug Dev. Ind. Pharm. 24(12),1113–1128.
  • Reitman, S. and Frankel, S. (1957) “A colorimetric method for the determination of serum oxaloacetic and glutamic pyruvic transam- inases”, Am. J. Clin. Pathol. 28, 56–63, Cited in: Giulbault, G.G, ed, Handbook of Enzymatic Methods of Analysis (Marcel Dekker, Inc., New York and Basel), 1976. pp. 121–123.
  • Rivas, P., Cassels, B.K., Morello, A. and Repetto, Y. (1999) “Effects of some beta-carboline alkaloids on intact Trypanosoma cruzi epimastigotes”, Comp. Biol. Physiol. C. Pharmacol. Toxicol. Endocrinol. 122(1),27–31.
  • Sakuma, S., Hayashi, M. and Akashi, M. (2001) “Design of nanoparticles composed of graft co-polymers for oral peptide delivery”, Adv. Drug Deliv. Rev. 47(1),21–37.
  • Sanchez-Ramos, J.R. (1991) “Banisterine and Parkinson’s disease”, Clin. Neuropharmacol. 14(5),391–402.
  • Sarkar, S., Mandal, S., Sinha, J., Mukhopadhyay, S., Das, N. and Basu, M.K. (2003) “Quercetin: Critical evaluation as an antileishmanial agent in vivo in hamsters using different vesicular delivery modes”, J. Drug Target. 10, 573–578.
  • Seyler, I., Morin, C., Barratt, G., Appel, M., Devissaguet, J.P. and Puisieux, F. (1995) “Induction of macrophage NO synthase by an immunomodulator entrapped within polymeric nanocapsules”, Eur. J. Pharm Biopharm. 41(1),49–54.
  • Shi, C.C., Liao, J.F. and Chen, C.F. (2001) “Spasmolytic affects of three harmala alkaloids on guinea-pig isolated trachea”, Pharmacol. Toxicol. 89(5),259–264.
  • Shi, C.C., Liao, J.F. and Chen, C.F. (2001) “Comparative study on the vasorelaxant effects of three harmala alkaloids in vitro”, Jpn. J. Pharmacol. 85(3),299–305.
  • Sinha, J., Raay, B., Das, N., Medda, S., Garai, S., Mahato, S.B. and Basu, M.K. (2002) “Bacopasaponin C: critical evaluation of antileishmanial properties in various delivery modes”, Drug Deliv. 9, 55–62.
  • Sobhani, A.M., Ebrahim, S.A. and Mohmoudian, M. (2002) “An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta-carboline alkaloids”, J. Pharm. Phar. Sci. 5(1),19–23.
  • Sourkes, T.L. (1999) “Rational hope in the early treatment of Parkinson’s disease”, Can. J. Physiol. Pharmacol. 77(6),375–382.
  • Stauber, L.A., Franchino, E. and Grun, J. (1958) “An eight-day method for screening compounds against Leishmania donovani in golden hamster”, J. Protozool. 5, 263–273.
  • Uezeno, T., Maruyama, W., Matsubara, K., Naoi, M., Shimizu, K., Saito, O., Ogawa, K., Mizukami, H., Hayase, N. and Shiono, H. (2001) “Norharman, an indoleamine-derived beta-carboline, but not Trp-P-2, a gamma carboline, induces apoptotic cell death in human neuroblastoma SH-SY5Y cells”, J. Neural. Transm. 108(8-9), 943–953.
  • Vijayanathan, V., Thomas, T. and Thomas, T.J. (2002) “DNA nanoparticles and development of DNA delivery vehicles for gene therapy”, Biochemistry 41(48),4085–4094.
  • Yoshioka, T., Sternberg, B. and Florence, A.T. (1994) “Preparation and properties of vesicles (niosomes) of sorbitan monoesters (Span 20, 30, 60 and 80) and a sorbitan triester(Span 85)”, Int. J. Pharm. 105, 1– 6.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.