Optimisation of peptides that actively cross the tympanic membrane by random amino acid extension: a phage display study

References

• Coco AS. Cost-effectiveness analysis of treatment options for acute otitis media. Ann Fam Med. 2007;5:29–38.
   PubMed Web of Science ®Google Scholar
• Casselbrant M, Mandel E, Rockette H, et al. Recent advances in otitis media: incidence of OM and bacteriology of acute OM during the first two years of life. Toronto: Decker; 1993.
   Google Scholar
• Pichichero ME. Ten-year study of acute otitis media in Rochester, NY. Pediatr Infect Dis J. 2016;35:1027–1032.
   PubMed Web of Science ®Google Scholar
• Teele DW, Klein JO, Rosner B. Epidemiology of otitis media during the first seven years of life in children in greater Boston: a prospective, cohort study. J Infect Dis. 1989;160:83–94.
   PubMed Web of Science ®Google Scholar
• Wallis S, Atkinson H, Coatesworth AP. Chronic otitis media. Postgrad Med. 2015;127:391–395.
   PubMed Web of Science ®Google Scholar
• Rovers MM. The burden of otitis media. Vaccine. 2008;26 Suppl 7:G2–G4.
   PubMed Web of Science ®Google Scholar
• Klein JO. The burden of otitis media. Vaccine. 2000;19 Suppl 1:S2–S8.
   PubMed Web of Science ®Google Scholar
• Ahmed S, Shapiro NL, Bhattacharyya N. Incremental health care utilization and costs for acute otitis media in children. Laryngoscope. 2014;124:301–305.
   PubMed Web of Science ®Google Scholar
• Cullen KA, Hall MJ, Golosinskiy A. Ambulatory surgery in the United States, 2006. Natl Health Stat Rep. 2009;1:1–25.
   Google Scholar
• Stangerup SE, Tos M, Arnesen R, et al. A cohort study of point prevalence of eardrum pathology in children and teenagers from age 5 to age 16. Eur Arch Otorhinolaryngol. 1994;251:399–403.
   PubMed Web of Science ®Google Scholar
• Joglekar S, Morita N, Cureoglu S, et al. Cochlear pathology in human temporal bones with otitis media. Acta Otolaryngol. 2010;130:472–476.
   PubMed Web of Science ®Google Scholar
• Friel-Patti S, Finitzo T. Recent advances in otitis media: speech-language learning in the first 3 years in children with tympanostomy tubes for recurrent or persistent OM. Toronto: Decker; 1993. p. 523–552.
   Google Scholar
• Klausen O, Møller P, Holmefjord A, et al. Lasting effects of otitis media with effusion on language skills and listening performance. Acta Otolaryngol Suppl. 2000;543:73–76.
   PubMedGoogle Scholar
• Wendler-Shaw P, Menyuk P, Teele D. Recent advances in otitis media: effects of otitis media in first year of life on language production in the second year of life. Toronto: Decker; 1993.
   Google Scholar
• Friel-Patti S, Finitzo-Hieber T, Conti G, et al. Language delay in infants associated with middle ear disease and mild, fluctuating hearing impairment. Pediatr Infect Dis. 1982;1:104–109.
   PubMedGoogle Scholar
• Klein J, Chase C, Teele D, et al. Recent advances in otitis media: OM and the development of speech, language and cognitive abilities at 7 years of age. Toronto: Decker; 1988.
   Google Scholar
• Arguedas A, Kvaerner K, Liese J, et al. Otitis media across nine countries: disease burden and management. Int J Pediatr Otorhinolaryngol. 2010;74:1419–1424.
   PubMed Web of Science ®Google Scholar
• American Academies of Family Physicians, ENT-HNS and Pediatrics. OM with effusion. Pediatrics. 2004;113:1412–1429.
   PubMed Web of Science ®Google Scholar
• Coco A, Vernacchio L, Horst M, et al. Management of acute otitis media after publication of the 2004 AAP and AAFP clinical practice guideline. Pediatrics. 2010;125:214–220.
   PubMed Web of Science ®Google Scholar
• Grossman Z, Branski D. Changing the therapeutic approach to acute OM in children. Harefuah. 2004;143:277–282.
   PubMedGoogle Scholar
• Heidemann CH, Lous J, Berg J, et al. Danish guidelines on management of otitis media in preschool children. Int J Pediatr Otorhinolaryngol. 2016;87:154–163.
   PubMed Web of Science ®Google Scholar
• Vergison A. Microbiology of otitis media: a moving target. Vaccine. 2008;26 Suppl 7:G5–G10.
   PubMed Web of Science ®Google Scholar
• Casey J, Adlowitz D, Pichichero M. New patterns in the otopathogens causing acute OM 6-8 years after introduction of pneumococcal conjugate vaccine. Pediatr Infect Dis J. 2010;29:304–309.
   PubMed Web of Science ®Google Scholar
• Schraff SA. Contemporary indications for ventilation tube placement. Curr Opin Otolaryngol Head Neck Surg. 2008;16:406–411.
   PubMed Web of Science ®Google Scholar
• Daly KA, Hunter LL, Lindgren BR, et al. Chronic otitis media with effusion sequelae in children treated with tubes. Arch Otolaryngol Head Neck Surg. 2003;129:517–522.
   PubMedGoogle Scholar
• de Beer BA, Schilder AG, Ingels K, et al. Hearing loss in young adults who had ventilation tube insertion in childhood. Ann Otol Rhinol Laryngol. 2004;113:438–444.
   PubMed Web of Science ®Google Scholar
• Johnston LC, Feldman HM, Paradise JL, et al. Tympanic membrane abnormalities and hearing levels at the ages of 5 and 6 years in relation to persistent otitis media and tympanostomy tube insertion in the first 3 years of life: a prospective study incorporating a randomized clinical trial. Pediatrics. 2004;114:e58–e67.
   PubMed Web of Science ®Google Scholar
• Pichichero ME, Reed MD. Variations in amoxicillin pharmacokinetic/pharmacodynamic parameters may explain treatment failures (4) acute otitis media. Pediatric Drugs. 2009;11:243–249.
   PubMedGoogle Scholar
• McFarland LV. Epidemiology, risk factors and treatments for antibiotic-associated diarrhea. Dig Dis. 1998;16:292–307.
   PubMed Web of Science ®Google Scholar
• Zielnik-Jurkiewicz B, Bielicka A. Antibiotic resistance of Streptococcus pneumoniae in children with acute otitis media treatment failure. Int J Pediatr Otorhinolaryngol. 2015;79:2129–2133.
   PubMed Web of Science ®Google Scholar
• Kurabi A, Pak K, Bernhardt M, et al. Discovery of a biological mechanism of active transport through the tympanic membrane to the middle ear. Sci Rep. 2016;6:22663.
   PubMed Web of Science ®Google Scholar
• Grau-Campistany A, Strandberg E, Wadhwani P, et al. Hydrophobic mismatch demonstrated for membranolytic peptides, and their use as molecular rulers to measure bilayer thickness in native cells. Sci Rep. 2015;5:9388.
   PubMed Web of Science ®Google Scholar
• Wu CH, Liu IJ, Lu RM, et al. Advancement and applications of peptide phage display technology in biomedical science. J Biomed Sci. 2016;23:8.
   PubMed Web of Science ®Google Scholar
• Hernandez M, Leichtle A, Pak K, et al. Myeloid differentiation primary response gene 88 is required for the resolution of otitis media. J Infect Dis. 2008;198:1862–1869.
   PubMed Web of Science ®Google Scholar
• Leichtle A, Hernandez M, Ebmeyer J, et al. CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF−/− mice. J Immunol. 2010;184:3087–3097.
   PubMed Web of Science ®Google Scholar
• Lear S, Cobb SL. Pep-Calc.com: a set of web utilities for the calculation of peptide and peptoid properties and automatic mass spectral peak assignment. J Comput Aided Mol Des. 2016;30:271–277.
   PubMed Web of Science ®Google Scholar
• Maupetit J, Derreumaux P, Tuffery P. PEP-FOLD: an online resource for de novo peptide structure prediction [Web Server issue]. Nucleic Acids Res. 2009;37:W498–W503.
   PubMed Web of Science ®Google Scholar
• Altschul SF, Gish W, Miller W, et al. Basic local alignment search tool. J Mol Biol. 1990;215:403–410.
   PubMed Web of Science ®Google Scholar
• Kurabi A, Beasley KA, Chang L, et al. Peptides actively transported across the tympanic membrane: functional and structural properties. PLoS One. 2017;12:e0172158.
   PubMed Web of Science ®Google Scholar
• Bulbake U, Doppalapudi S, Kommineni N, et al. Liposomal formulations in clinical use: an updated review. Pharmaceutics. 2017;9:e12.
   PubMed Web of Science ®Google Scholar