17
Views
18
CrossRef citations to date
0
Altmetric
Original Articles

Application of Neural Networks in the QSAR Analysis of Percent Effect Biological Data: Comparison with Adaptive Least Squares and Nonlinear Regression Analysis

&
Pages 137-152 | Received 10 Jun 1992, Accepted 01 Nov 1992, Published online: 24 Sep 2006

References

  • Schaper , K.-J. and Saxena , A. K. 1991 . “ QSAR analysis of dose and property dependent activity classes of homologous drugs ” . In QSAR: Rational Approaches to the Design of Bioactive Compounds , Edited by: Silipo , C. and Vittoria , A. 45 – 48 . Amsterdam : Elsevier .
  • Schaper , K.-J. 1987 . “ QSAR analysis of logit-transformed dose response curves and dose response curve fragments of sets of compounds ” . In QSAR in Drug Design and Toxicology , Edited by: Hadzy , D. and Jerman-Blazic , B. 58 – 60 . Amsterdam : Elsevier .
  • Wiese , M. 1991 . Application of neural networks in the analysis of percent effect biological data . Quant. Struct.-Act. Relat. , 10 : 369 – 371 .
  • Tamaru , A. , Ogawa , H. , Nishimura , T. , Takahashi , Y. and Sasaki , S. 1988 . Structure-activity study of systemic acaricidal N-substituted chloromethanesulfonamides by the ORMUCS method . J. Pesticide Sci. , 13 : 1 – 6 .
  • Rao , J. , Saxena , A. K. , Saxena , R. M. , Singh , H. K. , Kar , K. and Srimal , R. C. 1987 . Synthesis of N-[3-propyl(thio/sulfono-propyl]heterocyclics as potential CNS/CVS agents . Indian J. Chem. , 26B : 761 – 765 .
  • McClelland , J. L. and Rumelhart , D. E. 1988 . Explorations in Parallel Distributed Processing: A Handbook of Models, Programs, and Exercises , Cambridge : MIT Press .
  • Kawashima , Y. , Amanuma , F. , Sato , M. , Okuyama , S. , Nakashima , Y. , Sota , K. and Moriguchi , I. 1986 . Structure-activity studies of 4,6-disubstituted 2-(morpholinocarbonyl)furo[3,2-b]indole derivatives with analgesic and antiinflammatory activities . J. Med. Chem. , 29 : 2284 – 2290 .
  • Aoyama , T. , Suzuki , Y. and Ichikawa , H. 1990 . Neural networks applied to structure-activity relationships . J. Med. Chem. , 33 : 905 – 908 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.