Serotonin Dysregulation and Psychopathology in Anorexia Nervosa and Obsessive-Compulsive Disorder

References

• Ananth , J. 1986 . Clomipramine: An antiobsessive drug . Canadian Journal of Psychiatry , 31 : 253 – 258 .
   PubMed Web of Science ®Google Scholar
• Bendotti , C. and Samanin , R. 1987 . The role of putative 5-HT1A and 5-HT1B receptors in the control of feeding in rats . Life Science , 41 : 635 – 642 .
   PubMed Web of Science ®Google Scholar
• Beumont , P. J. V. , George , G. C. W. and Smart , D. E. 1976 . “Dieters” and “vomiters and purgers” in anorexia nervosa . Psychological Medicine , 6 : 617 – 622 .
   PubMed Web of Science ®Google Scholar
• Blundell , J. E. and Hill , A. J. 1987 . Serotoninergic modulation of the pattern of eating and the profile of hunger-satiety in humans . International Journal of Obesity , 11 : 141 – 155 .
   PubMedGoogle Scholar
• Blundell , J. E. and Rogers , P. 1980 . Effects of anorexic drugs on food intake, food selection and preferences, hunger motivation and subjective experiences: Drugs as tools for the investigation of human feeding . Appetite , 1 : 151 – 165 .
   Google Scholar
• Brewerton , T. D. , Brandt , H. A. , Lesem , M. D. , Murphy , D. L. and Jimerson , D. C. Eating disorders, anxiety and serotonin [Summary] . CME Syllabus & Proceedings Summary of the 143rd Annual Meeting of the American Psychiatric Association . pp. 215
   Google Scholar
• Brewerton , T. D. , Mueller , E. A. , Lesem , M. D. , Brandt , H. A. , Quearry , B. , George , D. T. , Murphy , D. L. and Jimerson , D. C. 1992 . Neuroendocrine responses to m-chlorophenylpiperazine and L-tryptophan in bulimia . Archives of General Psychiatry , 49 : 852 – 861 .
   PubMed Web of Science ®Google Scholar
• Brown , G. L. , Ebert , M. H. , Goyer , P. F. , Jimerson , D. C. , Klein , W. J. , Bunney , W. E. and Goodwin , F. C. 1982 . Aggression, suicide and serotonin: Relationship to CSF amine metabolites . American Journal of Psychiatry , 139 : 741 – 746 .
   PubMed Web of Science ®Google Scholar
• Buttinger , C. , Hollander , E. and Walsh , B. T. M-CPP challenges in anorexia nervosa [Summary] . CME Syllabus & Proceedings Summary of the 143rd Annual Meeting of the American Psychiatric Association . pp. 215
   Google Scholar
• Cantwell , D. P. , Sturzenberger , S. , Burroughs , J. , Salkin , B. and Green , J. K. 1977 . Anorexia nervosa: An affective disorder? . Archives of General Psychiatry , 34 : 1087 – 1093 .
   PubMed Web of Science ®Google Scholar
• Carruba , M. O. , Mantegazza , P. , Memo , M. , Missale , C. , Pizzi , M. and Spano , P. F. 1986 . Peripheral and central mechanisms of action of serotoninergic anorectic drugs . Appetite , 7 : 105 – 113 .
   Google Scholar
• Casper , R. C. 1990 . Personality features of women with good outcome from restricting anorexia nervosa . Psychosomatic Medicine , 52 : 156 – 170 .
   PubMed Web of Science ®Google Scholar
• Casper , R. C. , Hedeker , D. and McClough , J. F. 1992 . Personality dimensions in eating disorders and their relevance for subtyping . Journal of the American Academy of Child and Adolescent Psychiatry , 31 : 830 – 840 .
   PubMed Web of Science ®Google Scholar
• Channon , S. and DeSilva , W. P. 1985 . Psychological correlates of weight gain in patients with anorexia nervosa . Journal of Psychiatric Research , 19 : 267 – 271 .
   PubMed Web of Science ®Google Scholar
• Charney , D. S. , Goodman , W. K. , Price , L. H. , Woods , S. W. , Rasmussen , S. A. and Heninger , G. R. 1988 . Serotonin function in obsessive-compulsive disorder: A comparison of the effects of tryptophan and m-chlorophenylpiperazine in patients and healthy subjects . Archives of General Psychiatry , 45 : 177 – 185 .
   PubMed Web of Science ®Google Scholar
• Crisp , A. H. 1984 . “ The psychopathology of anorexia nervosa: Getting the “heat” out of the system ” . In Eating and its disorders , Edited by: Stunkard , A. J. and Stellar , E. 209 – 233 . New York : Raven Press .
   Google Scholar
• Crisp , A. H. , Lacey , H. and Crutchfield , M. 1987 . Clomipramine and “drive” in people with anorexia nervosa: An in-patient study . British Journal of Psychiatry , 150 : 355 – 358 .
   PubMed Web of Science ®Google Scholar
• DeVeaugh-Geiss , J. , Landau , P. and Katz , R. 1989 . Treatment of obsessive-compulsive disorder with clomipramine . Psychiatric Annals , 19 : 97 – 101 .
   Web of Science ®Google Scholar
• DeVeaugh-Geiss , J. , Moroz , G. , Biederman , J. , Cantwell , D. , Fontaine , R. , Greist , J. H. , Reichler , R. , Katz , R. and Landau , P. 1992 . Clomipramine hydrochloride in childhood and adolescent obsessive-compulsive disorder: A multicenter trial . Journal of the American Academy of Child and Adolescent Psychiatry , 31 : 45 – 49 .
   PubMed Web of Science ®Google Scholar
• Dourish , C. T. , Hutson , P. H. , Kennett , G. A. and Curzon , G. 1986 . 8-OH-D-DPAT-induced hyperphagia: Its neutral basis and possible therapeutic relevance . Appetite , 7 : 127 – 140 .
   Google Scholar
• DuBois , F. S. 1949 . Compulsion neurosis with cachexia (anorexia nervosa) . American Journal of Psychiatry , 106 : 107 – 115 .
   PubMed Web of Science ®Google Scholar
• Eison , M. S. 1990 . Azapirones: Mechanism of action in anxiety and depression . Drug Therapy , 8 : 308
   Google Scholar
• Fahy , T. A. 1991 . Obsessive-compulsive symptoms in eating disorders . Behavior Research and Therapy , 29 : 113 – 116 .
   PubMedGoogle Scholar
• Feldman , R. S. and Smith , W. C. 1978 . Clordiazepoxide-fluoxetine interactions on food intake in free-feeding rats . Pharmacology, Biochemistry and Behavior , 8 : 749 – 752 .
   Google Scholar
• Ferguson , J. M. 1987 . Treatment of an anorexia nervosa patient with fluoxetine . American Journal of Psychiatry , 144 : 1239
   Google Scholar
• Fernstrom , J. D. and Wurtman , R. J. 1971 . Brain serotonin content: Increase following ingestion of carbohydrate diet . Science , 174 : 1023 – 1025 .
   PubMed Web of Science ®Google Scholar
• File , S. E. , Hyde , J. R. and MacLeod , N. C. 1979 . 5,7-dihydroxy-tryptamine lesions of dorsal and median raphe nuclei and performance in the social interaction test of anxiety and in a home-cage aggression test . Journal of Affective Disorders , 1 : 115 – 122 .
   PubMedGoogle Scholar
• Flament , M. F. , Rapoport , J. L. , Berg , C. J. , Sceery , W. , Kilts , C. , Mellström , B. and Linnoila , M. 1985 . Clomipramine treatment of childhood obsessive-compulsive disorder: A double-blind controlled study . Archives of General Psychiatry , 42 : 977 – 983 .
   PubMed Web of Science ®Google Scholar
• Flament , M. F. , Rapoport , J. L. , Murphy , D. L. , Berg , C. J. and Lake , C. R. 1987 . Biochemical changes during clomipramine treatment of childhood obsessive-compulsive disorder . Archives of General Psychiatry , 44 : 219 – 225 .
   PubMed Web of Science ®Google Scholar
• Fluoxetine Bulimia Nervosa Collaborative (FBNC) Study Group . 1992 . Fluoxetine in the treatment of bulimia nervosa: A multicenter, placebo-controlled, double-blind trial . Archives of General Psychiatry , 49 : 139 – 147 .
   Google Scholar
• Fontaine , R. and Chouinard , G. 1986 . An open clinical trial of fluoxetine in the treatment of obsessive-compulsive disorder . Journal of Clinical Psychopharmacology , 6 : 98 – 101 .
   PubMed Web of Science ®Google Scholar
• Goodman , W. K. , Price , L. H. , Rasmussen , S. A. , Mazure , C. , Delgado , P. , Heninger , G. R. and Charney , D. S. 1989 . The Yale-Brown Obsessive-Compulsive Scale: II. Validity . Archives of General Psychiatry , 46 : 1012 – 1016 .
   PubMed Web of Science ®Google Scholar
• Gray , J. A. 1982 . Precis of the neuropsychology of anxiety: An enquiry into the functions of the septohippocampal system . Behavioral and Brain Sciences , 5 : 469 – 534 .
   Web of Science ®Google Scholar
• Gwirtsman , H. E. , Guze , B. H. , Yager , J. and Gainsley , B. 1990 . Fluoxetine treatment of anorexia nervosa: An open clinical trial . Journal of Clinical Psychiatry , 51 : 378 – 382 .
   PubMed Web of Science ®Google Scholar
• Halmi , K. , Brodland , G. and Loney , J. 1973 . Prognosis of anorexia nervosa . Annals of Internal Medicine , 78 : 907 – 909 .
   PubMed Web of Science ®Google Scholar
• Halmi , K. A. , Eckert , E. , Marchi , P. , Sampugnaro , V. , Apple , R. and Cohen , J. 1991 . Comorbidity of psychiatric diagnoses in anorexia nervosa . Archives of General Psychiatry , 48 : 712 – 718 .
   PubMed Web of Science ®Google Scholar
• Holland , A. , Sicotte , N. and Treasure , J. 1988 . Anorexia nervosa: Evidence for a genetic basis . Journal of Psychosomatic Research , 32 : 561 – 571 .
   PubMed Web of Science ®Google Scholar
• Hsu , L. K. G. , Crisp , A. H. and Callender , J. S. 1992 . Psychiatric diagnoses in recovered and unrecovered anorectics 22 years after onset of illness: A pilot study . Comprehensive Psychiatry , 33 : 123 – 127 .
   PubMed Web of Science ®Google Scholar
• Insel , T. R. , Mueller , E. A. , Alterman , I. , Linnoila , M. and Murphy , D. L. 1985 . Obsessive-compulsive disorder and serotonin: Is there a connection? . Biological Psychiatry , 20 : 1174 – 1188 .
   PubMed Web of Science ®Google Scholar
• Jenike , M. A. , Buttolph , L. , Baer , L. , Ricciardi , J. and Holland , A. 1989 . Open trial of fluoxetine in obsessive-compulsive disorder . American Journal of Psychiatry , 146 : 909 – 911 .
   PubMed Web of Science ®Google Scholar
• Jimerson , D. C. , Lesem , M. D. , Kaye , W. H. and Brewerton , T. D. 1992 . Low serotonin and dopamine metabolite concentrations in cerebrospinal fluid from bulimic patients with frequent binge episodes . Archives of General Psychiatry , 49 : 132 – 138 .
   PubMed Web of Science ®Google Scholar
• Joffe , R. T. and Swinson , R. P. 1987 . Eating attitudes test scores of patients with obsessive-compulsive disorder . American Journal of Psychiatry , 144 : 1510 – 1511 .
   Google Scholar
• Kantak , K. M. , Hegstrand , L. R. and Eichelman , B. 1981 . Dietary tryptophan reversal of septal lesion and 5,7-DHT lesion elicited by shock-induced fighting . Pharmacology, Biochemistry and Behavior , 15 : 343 – 350 .
   Google Scholar
• Kasvikis , Y. G. , Tsakiris , F. , Marks , I. M. , Basoglu , M. and Noshirvani , H. F. 1986 . Past history of anorexia nervosa in women with obsessive-compulsive disorder . International Journal of Eating Disorders , 5 : 1069 – 1075 .
   Google Scholar
• Katz , R. J. 1980 . Role of serotonergic mechanisms in animal models of predation . Progress in Neuropsychopharmacology , 4 : 219 – 231 .
   PubMedGoogle Scholar
• Kaye , W. H. , Ebert , M. H. , Gwirtsman , H. E. and Weiss , S. R. 1984 . Differences in brain serotonergic metabolism between nonbulimic and bulimic patients with anorexia nervosa . American Journal of Psychiatry , 141 : 1598 – 1601 .
   PubMed Web of Science ®Google Scholar
• Kaye , W. H. , Gwirtsman , H. E. , George , D. T. and Ebert , M. H. 1991a . Altered serotonin activity in anorexia nervosa after long-term weight restoration: Does elevated cerebrospinal fluid 5-hydroxyindoleacetic acid level correlate with rigid and obsessive behavior? . Archives of General Psychiatry , 48 : 556 – 562 .
   PubMed Web of Science ®Google Scholar
• Kaye , W. H. , Weltzin , T. E. , Hsu , L. K. G. and Bulik , C. M. 1991b . An open trial of fluoxetine in patients with anorexia nervosa . Journal of Clinical Psychiatry , 52 : 464 – 471 .
   PubMed Web of Science ®Google Scholar
• Kaye , W. H. , Weltzin , T. E. , Hsu , L. K. G. , Bulik , C. , McConaha , C. and Sobkiewicz , T. 1992 . Patients with anorexia nervosa have elevated scores on the Yale-Brown Obsessive-Compulsive Scale . International Journal of Eating Disorders , 12 : 57 – 62 .
   Web of Science ®Google Scholar
• Kruesi , M. J. P. , Rapoport , J. L. , Hamburger , S. , Hibbs , E. , Potter , W. Z. , Lenane , M. and Brown , G. L. 1990 . Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents . Archives of General Psychiatry , 47 : 419 – 426 .
   PubMed Web of Science ®Google Scholar
• Kruesi , M. J. P. , Hibbs , E. D. Zahn , T. P. 1992 . A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders: Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures? . Archives of General Psychiatry , 49 : 429 – 435 .
   PubMed Web of Science ®Google Scholar
• Lacey , J. H. and Crisp , A. H. 1980 . Hunger, food intake and weight: The impact of clomipramine on a refeeding anorexia nervosa population . Postgraduate Medical Journal , 56 : 79 – 85 .
   PubMed Web of Science ®Google Scholar
• Leibowitz , S. F. 1978 . Paraventricular nucleus: A primary site mediating adrenergic stimulation of feeding and drinking . Pharmacology, Biochemistry and Behavior , 8 : 163 – 175 .
   PubMed Web of Science ®Google Scholar
• Leibowitz , S. F. 1980 . “ Neurochemical systems of the hypothalamus: Control of feeding and drinking behavior and water-electrolyte excretion ” . In Handbook of the hypothalamus , Edited by: Morgane , P. J. and Panksepp , J. 299 – 437 . New York : Dekker .
   Google Scholar
• Leibowitz , S. F. , Weiss , G. F. and Shor-Posner , G. 1987 . Medial hypothalamic serotonin in the control of eating behavior . International Journal of Obesity , 11 : 110 – 123 .
   Google Scholar
• Leibowitz , S. F. , Weiss , G. F. , Yee , F. and Tretter , J. R. 1985 . Noradrenergic innervation of the paraventricular nucleus: Specific role in carbohydrate ingestion . Brain Research Bulletin , 14 : 561 – 567 .
   PubMed Web of Science ®Google Scholar
• Leonard , H. L. , Swedo , S. E. , Rapoport , J. L. , Koby , E. V. , Lenane , M. C. , Cheslow , D. L. and Hamburger , S. D. 1989 . Treatment of obsessive-compulsive disorder with clomipramine and desipramine in children and adolescents: A double-blind crossover comparison . Archives of General Psychiatry , 46 : 1088 – 1092 .
   PubMed Web of Science ®Google Scholar
• Liebowitz , M. , Hollander , E. , Schneier , F. , Campeas , R. , Hatterer , J. , Papp , L. , Fairbanks , J. , Sandberg , D. , Davies , S. and Stein , M. 1989 . Fluoxetine treatment of obsessive-compulsive disorder: An open clinical trial . Journal of Clinical Psychopharmacology , 9 : 423 – 427 .
   PubMed Web of Science ®Google Scholar
• Lingjaerde , O. 1984 . Platelet serotonin uptake inhibition as a basis for monitoring antidepressant drug treatment . Journal of Clinical Psychopharmacology , 4 : 76 – 81 .
   Google Scholar
• Martin , G. R. 1990 . Current problems and future requirements for 5-hydroxytryptamine receptor classification . Neuropsychopharmacology , 3 : 321 – 333 .
   Google Scholar
• Mavissakalian , M. , Turner , S. M. , Michelson , L. and Jacob , R. 1985 . Tricyclic antidepresants in obsessive-compulsive disorder: Antiobsessional or antidepressant agents? II . American Journal of Psychiatry , 142 : 572 – 576 .
   PubMed Web of Science ®Google Scholar
• Noshirvani , H. F. , Kasvikis , Y. , Marks , I. M. , Tsakiris , F. and Monteiro , W. O. 1991 . Gender-divergent aetiological factors in obsessive-compulsive disorder . British Journal of Psychiatry , 158 : 260 – 263 .
   PubMed Web of Science ®Google Scholar
• Oliveros , S. C. , Iruela , L. M. , Caballero , L. and Baca , E. 1992 . Fluoxetine-induced anorexia in a bulimic patient . American Journal of Psychiatry , 149 : 1113 – 1114 .
   Web of Science ®Google Scholar
• Palmer , H. D. and Jones , M. S. 1938 . Anorexia nervosa as a manifestation of compulsion neurosis . Archives of Neurology and Psychiatry , 40 : 856 – 858 .
   Google Scholar
• Pazos , A. and Palacios , J. M. 1985 . Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I: Serotonin-1 receptors . Brain Research , 346 : 205 – 230 .
   PubMed Web of Science ®Google Scholar
• Pigott , T. A. , Altemus , M. , Rubenstein , C. S. , Hill , J. L. , Bihari , K. , L'Heureux , F. , Bernstein , S. and Murphy , D. L. 1991a . Symptoms of eating disorders in patients with obsessive-compulsive disorder . American Journal of Psychiatry , 148 : 1552 – 1557 .
   Google Scholar
• Pigott , T. , Grady , T. , Rubenstein , C. S. , L'Heureux , F. , Altemus , M. , Bihari , K. and Murphy , D. OCD and eating disorder: A comparison of symptom overlap . Presented at the annual meeting of the Association for the Advancement of Behavior Therapy . New York.
   Google Scholar
• Pigott , T. A. , Pato , M. T. , Bernstein , S. E. , Grover , G. N. , Hill , J. L. , Tolliver , T. J. and Murphy , D. L. 1990 . Controlled comparisons of clomipramine and fluoxetine in the treatment of obsessive-compulsive disorder . Archives of General Psychiatry , 47 : 926 – 932 .
   PubMed Web of Science ®Google Scholar
• Piran , N. , Kennedy , S. , Garfinkel , P. E. and Owens , M. 1985 . Affective disturbance in eating disorders . Journal of Nervous and Mental Disease , 17 : 395 – 400 .
   Google Scholar
• Przewlocka , B. , Stala , L. and Scheel-Kruger , J. 1979 . Evidence that GABA in the nucleus dorsalis raphe induces stimulation of locomotor activity and eating behavior . Life Sciences , 25 : 937 – 946 .
   Google Scholar
• Rastam , M. 1992 . Anorexia nervosa in 51 Swedish adolescents: Premorbid problems and comorbidity . Journal of the American Academy of Child and Adolescent Psychiatry , 31 : 819 – 829 .
   PubMed Web of Science ®Google Scholar
• Riddle , M. A. , Hardin , M. T. , King , R. , Scahill , L. and Woolston , J. L. 1990 . Fluoxetine treatment of children and adolescents with Tourette's and obsessive-compulsive disorders: Preliminary clinical experience . Journal of the American Academy of Child and Adolescent Psychiatry , 29 : 45 – 48 .
   PubMed Web of Science ®Google Scholar
• Riddle , M. A. , Scahill , L. , King , R. A. , Hardin , M. T. , Anderson , G. M. , Ort , S. I. , Smith , J. C. , Leckman , J. F. and Cohen , D. J. 1992 . Double-blind crossover trial of fluoxetine and placebo in children and adolescents with obsessive-compulsive disorder . Journal of the American Academy of Child and Adolescent Psychiatry , 31 : 1062 – 1069 .
   PubMed Web of Science ®Google Scholar
• Rothenberg , A. 1986 . Eating disorder as a modern obsessive-compulsive syndrome . Psychiatry , 49 : 45 – 53 .
   PubMed Web of Science ®Google Scholar
• Rothenberg , A. 1990 . Adolescence and eating disorder: The obsessive-compulsive syndrome . Psychiatric Clinics of North America , 13 : 469 – 488 .
   PubMed Web of Science ®Google Scholar
• Rydin , E. , Schalling , D. and Asberg , M. 1982 . Rorschach ratings in depressed and suicidal patients with low levels of 5-hydroxyindoleacetic acid in cerebrospinal fluid . Psychiatry Research , 7 : 229 – 243 .
   PubMed Web of Science ®Google Scholar
• Schoenfeld , R. I. 1976 . Lysergic acid diethylamide and mescaline-induced attenuation of the effect of punishment in the rat . Science , 192 : 801 – 802 .
   Google Scholar
• Shephard , R. A. and Broadhurst , P. L. 1982 . Effects of diazepam and of serotonin agoninsts on hyponeophagia in rats . Neuropharmacology , 21 : 337 – 340 .
   Google Scholar
• Shor-Posner , G. , Grinker , J. A. , Marinescu , C. , Brown , O. and Leibowitz , S. F. 1986 . Hypothalamic serotonin in the control of meal patterns and macronutrient selection . Brain Research Bulletin , 17 : 663 – 671 .
   PubMed Web of Science ®Google Scholar
• Shor-Posner , G. , Grinker , J. A. , Marinescu , C. and Leibowitz , S. F. 1985 . Role of hypothalamic norepinephrine in control of meal patterns . Physiology and Behavior , 35 : 209 – 214 .
   Google Scholar
• Silverstone , T. and Goodall , E. 1986 . Serotoninergic mechanisms in human feeding: The pharmacological evidence . Appetite , 7 : 85 – 97 .
   PubMed Web of Science ®Google Scholar
• Smart , D. E. , Beumont , P. J. V. and George , G. C. W. 1976 . Some personality characteristics of patients with anorexia nervosa . British Journal of Psychiatry , 128 : 57 – 60 .
   PubMed Web of Science ®Google Scholar
• Sohlberg , S. and Norring , C. 1989 . Ego functioning predicts first year status in adults with anorexia nervosa and bulimia nervosa . Acta Psychiatrica Scandinavica , 80 : 325 – 333 .
   PubMed Web of Science ®Google Scholar
• Solyom , L. , Freeman , R. J. and Miles , J. E. 1982 . A comparative psychometric study of anorexia nervosa and obsessive neurosis . Canadian Journal of Psychiatry , 27 : 282 – 286 .
   PubMed Web of Science ®Google Scholar
• Solyom , L. , Solyom , C. and Ledwidge , B. 1990 . The fluoxetine treatment of low-weight, chronic bulimia nervosa . Journal of Clinical Psychopharmacology , 10 : 421 – 425 .
   PubMed Web of Science ®Google Scholar
• Soubrié , P. 1986 . Reconciling the role of central serotonin neurons in human and animal behavior . Behavioral and Brain Sciences , 9 : 319 – 363 .
   Web of Science ®Google Scholar
• Stahl , S. M. 1992 . The current impact of neuroscience on psychotropic drug discovery and development . Psychopharmacology Bulletin , 28 : 3 – 9 .
   PubMed Web of Science ®Google Scholar
• Strober , M. 1980 . Personality and symptomatological features in young, nonchronic anorexia nervosa patients . Journal of Psychosomatic Research , 24 : 353 – 359 .
   PubMed Web of Science ®Google Scholar
• Strober , M. , Lampert , C. , Morrell , W. , Burroughs , J. and Jacobs . 1990 . A controlled family study of anorexia nervosa . International Journal of Eating Disorders , 9 : 239 – 253 .
   Web of Science ®Google Scholar
• Swift , W. J. , Andrews , D. and Barklage , N. E. 1986 . The relationship between affective disorder and eating disorders: A review of the literature . American Journal of Psychiatry , 143 : 290 – 299 .
   PubMed Web of Science ®Google Scholar
• Thiébot , M. H. , Hamon , M. and Soubrié , P. 1982 . Attenuation of induced anxiety in rats by chlordiazepoxide: Role of raphe dorsalis benzodiazepine binding sites and serotoninergic neurons . Neuroscience , 7 : 2287 – 2294 .
   Google Scholar
• Thoren , P. , Asberg , M. , Bertilsson , L. , Mellstrom , B. , Sjoqvist , F. and Traskman , L. 1980 . Clomipramine treatment of obsessive-compulsive disorder. II: Biochemical aspects . Archives of General Psychiatry , 37 : 1289 – 1294 .
   PubMed Web of Science ®Google Scholar
• Toner , B. B. , Garfinkel , P. E. and Garner , D. M. 1988 . Affective and anxiety disorders in the long-term follow-up of anorexia nervosa . International Journal of Psychiatry in Medicine , 18 : 357 – 364 .
   PubMed Web of Science ®Google Scholar
• Trimble , M. R. 1990 . Worldwide use of clomipramine . Journal of Clinical Psychiatry , 51 : S51 – 54 .
   PubMedGoogle Scholar
• Turner , S. M. , Jacob , R. C. , Beidel , D. S. and Himmelhoch , J. 1985 . Fluoxetine treatment of obsessive-compulsive disorder . Journal of Clinical Psychopharmacology , 5 : 207 – 212 .
   PubMed Web of Science ®Google Scholar
• Tye , N. C. , Everitt , B. J. and Iversen , S. D. 1977 . 5-hydroxytryptamine and punishment . Nature , 8 : 741 – 743 .
   Google Scholar
• Tye , N. C. , Iversen , S. D. and Green , A. R. 1979 . The effects of benzodiazepines and serotonergic manipulations on punished responding . Neuropharmacology , 18 : 689 – 695 .
   PubMed Web of Science ®Google Scholar
• Waldbillig , R. J. 1979 . The role of the dorsal and median raphe in the inhibition of muricide . Brain Research , 160 : 341 – 346 .
   Google Scholar
• Wilcox , J. A. 1990 . Fluoxetine and bulimia . Journal of Psychoactive Drugs , 22 : 81 – 82 .
   PubMed Web of Science ®Google Scholar
• Wise , C. D. , Berger , B. D. and Stein , L. Brain serotonin and unconditioned fear . Proceedings of the 78th Annual Convention of the American Psychological Association . pp. 821 – 822 .
   Google Scholar
• Wise , C. D. , Berger , B. D. and Stein , L. 1973 . Evidence of alpha-noradrenergic reward receptors and serotonergic punishment receptors in the rat brain . Biological Psychiatry , 6 : 3 – 21 .
   Google Scholar
• Wurtman , R. J. and Wurtman , J. J. 1984 . “ Nutritional control of central neurotransmitters ” . In The psychobiology of anorexia nervosa , Edited by: Perke , K. M. and Ploog , D. 4 – 11 . Berlin : Springer-Verlag .
   Google Scholar
• Yaryura-Tobias , J. A. , Bebirian , R. J. , Neziroglu , F. A. and Bhagavan , H. N. 1977 . Obsessive-compulsive disorder as a serotonergic defect . Research Communications in Psychology, Psychiatry, and Behavior , 2 : 279 – 286 .
   Google Scholar