198
Views
12
CrossRef citations to date
0
Altmetric
Articles

Decreased frequency of peripheral blood CD8+CD25+FoxP3+regulatory T cells correlates with IL-33 levels in pre-eclampsia

, , , , &
Pages 217-225 | Received 24 Jul 2016, Accepted 01 Mar 2017, Published online: 25 May 2017

References

  • LaMarca BD, Cornelius DC, Harmon AC, et al. Identifying immune mechanisms mediating the hypertension during preeclampsia. Am J Physiol Regul Integr Comp Physiol 2016;20:ajpregu.00052.2016.
  • Moreno-Eutimio MA, Tovar-Rodríguez JM, Vargas-Avila K, et al. Increased serum levels of inflammatory mediators and low frequency of regulatory T cells in the peripheral blood of preeclamptic Mexican women. Biomed Res Int 2014;2014:413249.
  • Schiess B. Inflammatory response in preeclampsia. Mol Aspects Med 2007;28:210–9.
  • Nie J, Li YY, Zheng SG, et al. FOXP3(+) Treg cells and gender bias in autoimmune diseases. Front Immunol 2015;28:493.
  • Cosmi L, Liotta F, Lazzeri E, et al. Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+regulatory thymocytes. Blood 2003;102:4107–14.
  • Wang R, Kozhaya L, Mercer F, et al. Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells. Proc Natl Acad Sci USA 2009;106:13439–44.
  • Jebbawi F, Fayyad-Kazan H, Merimi M, et al. A microRNA profile of human CD8(+) regulatory T cells and characterization of the effects of microRNAs on Treg cell-associated genes. J Transl Med 2014;6:218.
  • Taylor AL, Cross ELA, Llewelyn MJ. Induction of contact-dependent CD8+ Regulatory T cells through stimulation with staphylococcal and streptococcal superantigens. Immunology 2011;135:158–67.
  • Barbon CM, Davies JK, Voskertchian A, et al. Alloanergization of human T cells results in expansion of alloantigen-specific CD8(+) CD28(−)suppressor cells. Am J Transplant 2014;14:305–18.
  • Rahimzadeh M, Norouzian M, Arabpour F, Naderi N. Regulatory T-cells and preeclampsia: an overview of literature. Expert Rev Clin Immunol 2016;12:209–27.
  • Toldi G, Saito S, Shima T, et al. The frequency of peripheral blood CD4+ CD25high FoxP3+ and CD4+ CD25- FoxP3+ regulatory T cells in normal pregnancy and pre-eclampsia. Am J Reprod Immunol 2012;68:175–80.
  • Toldi G, Vásárhelyi ZE, Rigó J Jr, et al. Prevalence of regulatory T-cell subtypes in preeclampsia. Am J Reprod Immunol 2015;74:110–5.
  • Steinborn A, Schmitt E, Kisielewicz A, et al. Pregnancy-associated diseases are characterized by the composition of the systemic regulatory T cell (Treg) pool with distinct subsets of Tregs Clin Exp Immunol 2012;167:84–98.
  • Darmochwal-Kolarz D, Saito S, Tabarkiewicz J, et al. Apoptosis signaling is altered in CD4(+)CD25(+)FoxP3(+) T regulatory lymphocytes in pre-eclampsia. Int J Mol Sci 2012;13:6548–60.
  • Turner JA. Diagnosis and management of pre-eclampsia: an update. Int J Womens Health 2010;2:327–37.
  • Darmochwal-Kolarz D, Kludka-Sternik M, Tabarkiewicz J, et al. The predominance of Th17 lymphocytes and decreased number and function of Treg cells in preeclampsia. J Reproductive Immunol 2012;93:75–81.
  • Zeng B, Kwak-Kim J, Liu Y, et al. Treg cells are negatively correlated with increased memory B cells in pre-eclampsia while maintaining suppressive function on autologous B-cell proliferation. Am J Reproductive Immunol (New York, NY: 1989) 2013;70:454–63.
  • Teh PP, Vasanthakumar A, Kallies A. Development and function of effector regulatory T cells. Prog Mol Biol Transl Sci 2015;136:155–74.
  • Alijotas-Reig J, Melnychuk T, Gris JM. Regulatory T cells, maternal–foetal immune tolerance and recurrent miscarriage: new therapeutic challenging opportunities. Med Clin (Barc) 2015;144:265–8.
  • Luo CT, Li MO. Transcriptional control of regulatory T cell development and function. Trends Immunol 2013;34:531–9.
  • Cao W, Wang X, Chen T, et al. The expression of Notch/Notch ligand, IL-35, IL-17, and Th17/Treg in preeclampsia. Dis Markers 2015;2015:316182.
  • Lai Z, Kalkunte S, and Sharma S. A critical role of interleukin-10 in modulating hypoxia-induced preeclampsia-like disease in mice. Hypertension 2011;57:505–14.
  • Nevers T, Kalkunte S, Sharma S. Uterine regulatory T cells, IL-10 and hypertension. Am J Reprod Immunol 2011;66(Suppl 1):88–92.
  • Mittrücker HW, Visekruna A, Huber M. Heterogeneity in the differentiation and function of CD8+T cells. Arch Immunol Ther Exp (Warsz) 2014;62:449–58.
  • Feizollahzadeh S, Taheripanah R, Khani M, et al. Promoter region polymorphisms in the transforming growth factorbeta-1 (TGFβ1) gene and serum TGFβ1 concentration in preeclamptic and control Iranian women. J Reprod Immunol 2012;94:216–21.
  • Afzali B, Mitchell P, Lechler R, et al. Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells. Clin Exp Immunol 2010;159:120–30.
  • Darmochwal-Kolarz D, Kludka-Sternik M, Tabarkiewicz J, et al. The predominance of Th17 lymphocytes and decreased number and function of Treg cells in preeclampsia. J Reproductive Immunol 2012;93:75–81.
  • Toldi G, Rigó J Jr, Stenczer B, et al. Increased prevalence of IL-17-producing peripheral blood lymphocytes in pre-eclampsia. Am J Reprod Immunol 2011;66:223–9.
  • Granne I, Southcombe JH, Snider JV, et al. ST2 and IL-33 in pregnancy and pre-eclampsia. PLoS One 2011;6:e24463.
  • Stampalija T, Chaiworapongsa T, Romero R, et al. Maternal plasma concentrations of sST2 and angiogenic/anti-angiogenic factors in preeclampsia. J Matern Fetal Neonatal Med 2013;26:1359–70.
  • Matta BM, Lott JM, Mathews LR, et al. IL-33 is an unconventional alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells. J Immunol 2014;15;193:4010–20.
  • Matta BM, Turnquist HR. Expansion of regulatory T cells in vitro and in vivo by IL-33. Methods Mol Biol 2016;1371:29–41.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.