Trimethylamine-N-oxide (TMAO) increased aquaporin-2 expression in spontaneously hypertensive rats

References

• GBD 2015 Mortality and Causes of Death Collaborators. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016;388(10053):1459–544.
   PubMed Web of Science ®Google Scholar
• Sacco RL, Roth GA, Reddy KS, Arnett DK, Bonita R, Gaziano TA, Heidenreich PA, Huffman MD, Mayosi BM, Mendis S, et al. The heart of 25 by 25: achieving the goal of reducing global and regional premature deaths from cardiovascular diseases and stroke: a modeling study from the American Heart Association and World Heart Federation. Glob Heart. 2016;11(2):251–64.
   PubMed Web of Science ®Google Scholar
• Huang D, Zhou J, Su D, Yu W, Chen J Variations of perioperative baroreflex sensitivity in hypertensive and normotensive patients. Clin Exp Hypertens. 2017;39(1):74–79.
   PubMed Web of Science ®Google Scholar
• Ufnal M, Jazwiec R, Dadlez M, Drapala A, Sikora M, Skrzypecki J. Trimethylamine-N-oxide: a carnitine-derived metabolite that prolongs the hypertensive effect of angiotensin II in rats. Can J Cardiol. 2014;30:1700–05.
   PubMed Web of Science ®Google Scholar
• Ma M, Tan X, Zhu S. Prehypertension and its optimal indicator among adults in Hubei Province, Central China, 2013–2015. Clin Exp Hypertens. 2017;39(6):532–38.
   PubMed Web of Science ®Google Scholar
• Ufnal M, Zadlo A, Ostaszewski R. TMAO: a small molecule of great expectations. Nutrition. 2015;31(11–12):1317–23.
   PubMed Web of Science ®Google Scholar
• Yancey P, Clark M, Hand S, Bowlus R, Somero G. Living with water stress: evolution of osmolyte systems. Science (80-.). 1982;217(4566):1214–22.
   PubMed Web of Science ®Google Scholar
• Cho CE, Caudill MA. Trimethylamine-N-Oxide: friend, foe, or simply caught in the cross-fire? Trends Endocrinol Metab. 2017;28(2):121–30.
   PubMed Web of Science ®Google Scholar
• Koeth RA, Levison BS, Culley MK, Buffa JA, Wang Z, Gregory JC, Org E, Wu Y, Li L, Smith JD, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014;20(5):799–812.
   PubMed Web of Science ®Google Scholar
• Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, Dugar B, Feldstein AE, Britt EB, Fu X, Chung YM, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature. 2011;472(7341):57–63.
   PubMed Web of Science ®Google Scholar
• Zeisel SH. Dietary choline: biochemistry, physiology, and pharmacology. Annu Rev Nutr. 1981;1:95–121.
   PubMed Web of Science ®Google Scholar
• Zeisel SH, Wishnok JS, Blusztajn JK. Formation of methylamines from ingested choline and lecithin. J Pharmacol Exp Ther. 1983;225(2):320–24.
   PubMed Web of Science ®Google Scholar
• Seibel BA, Walsh PJ. Trimethylamine oxide accumulation in marine animals: relationship to acylglycerol storage. J Exp Biol. 2002;205:297–306.
   PubMed Web of Science ®Google Scholar
• Yancey PH. Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses. J Exp Biol. 2005;208:2819–30.
   PubMed Web of Science ®Google Scholar
• Wang A, Bolen DW. A naturally occurring protective system in urea-rich cells: mechanism of osmolyte protection of proteins against urea denaturation. Biochemistry. 1997;36:9101–08.
   PubMed Web of Science ®Google Scholar
• Nabil E, et al. Probiotic supplementation and trimethylamine-N-oxide production following a high-fat diet. Obesity. 2015;23:2357–63.
   PubMed Web of Science ®Google Scholar
• Wang K-L, Cheng H-M, Chuang S-Y, Spurgeon HA, Ting CT, Lakatta EG, Yin FC, Chou P, Chen CH Central or peripheral systolic or pulse pressure: which best relates to target-organs and future mortality? J Hypertens. 2009;27:461.
   PubMed Web of Science ®Google Scholar
• Roman MJ, Devereux RB, Kizer JR, Lee ET, Galloway JM, Ali T, Umans JG, Howard BV Central pressure more strongly relates to vascular disease and outcome than does brachial pressure the strong heart study. Hypertension. 2007;50:197–203.
   PubMed Web of Science ®Google Scholar
• Vlachopoulos C, Aznaouridis K, O’Rourke MF, Safar ME, Baou K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis. Eur Heart J. 2010;31:1865–71.
   PubMed Web of Science ®Google Scholar
• Galán-Cobo A, Ramírez-Lorca R, Echevarría M. Role of aquaporins in cell proliferation: what else beyond water permeability? Channels. 2016;10(3):185–201.
   PubMed Web of Science ®Google Scholar
• Ishibashi K, Kondo S, Hara S, Morishita Y. The evolutionary aspects of aquaporin family. Am J Physiol Regul Integr Comp Physiol. 2011;300:R566–R576.
   PubMed Web of Science ®Google Scholar
• Park EJ, Kwon TH. A minireview on vasopressin-regulated aquaporin-2 in kidney collecting duct cells. Electrolyte Blood Press. 2015;13:1–6.
   PubMedGoogle Scholar
• Ishikawa SE, Schrier RW. Pathophysiological roles of arginine vasopressin and aquaporin-2 in impaired water excretion. Clin Endoncrinol (Oxf). 2003;58:1–17.
   PubMed Web of Science ®Google Scholar
• Lee CR, Watkins ML, Patterson JH, Gattis W, O’connor CM, Gheorghiade M, Adams KF Jr. Vasopressin: a new target for the treatment of heart failure. Am Heart J. 2003;146:9–18.
   PubMed Web of Science ®Google Scholar
• Dixon MB, Lien YH. Tolvaptan and its potential in the treatment of hyponatremia. Ther Clin Risk Manag. 2008;4:1149–55.
   PubMedGoogle Scholar
• Ishikawa SE. Hyponatremia associated with heart failure: pathological role of vasopressin-dependent impaired water excretion. J Clin Med. 2015;4:933–47.
   PubMed Web of Science ®Google Scholar
• Robertson GL, Mahr EA, Athar S, Sinha T. Development and clinical application of a new method for the radioimmunoassay of arginine vasopressin in human plasma. J Clin Investig. 1973;52:2340–52.
   PubMed Web of Science ®Google Scholar
• Christensen BM, Wang W, Frøkiaer J, Nielsen S. Axial heterogeneity in basolateral AQP2 localization in rat kidney: effect of vasopressin. Am J Physiol Renal Physiol. 2003;284(4):F701–17.
   PubMed Web of Science ®Google Scholar
• Arnspang EC, Login FH, Koffman JS, Sengupta P, Nejsum LN AQP2 plasma membrane diffusion is altered by the degree of AQP2-S256 phosphorylation. Int J Mol Sci. 2016;17:11.
   Web of Science ®Google Scholar
• Wang Z, Wang Y, Chen Y, Lv J. The IL-24 gene protects human umbilical vein endothelial cells against H2O2-induced injury and may be useful as a treatment for cardiovascular disease. Int J Mol Med. 2016;37:581–92.
   PubMed Web of Science ®Google Scholar
• Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29:e45.
   PubMed Web of Science ®Google Scholar
• Hartiala J, Bennett BJ, Tang WH, Wang Z, Stewart AF, Roberts R, McPherson R, Lusis AJ, Hazen SL, Allayee H, CARDIoGRAM Consortium. Comparative genome-wide association studies in mice and humans for trimethylamine-N-oxide, a proatherogenic metabolite of choline and L-carnitine. Arteriosclerosis Thromb Vasc Biol. 2014;34:1307–13.
   PubMed Web of Science ®Google Scholar
• Caligiuri SPB, Pierce GN. A review of the relative efficacy of dietary, nutritional supplements, lifestyle, and drug therapies in the management of hypertension. Crit Rev Food Sci Nutr. 2017;57(16):3508–27. doi:10.1080/10408398.2016.1142420.
   PubMed Web of Science ®Google Scholar
• Liard JF. Effects of a specific antidiuretic agonist on cardiac output and its distribution in intact and anephric dogs. Clin Sci. 1998;74:239–239.
   Google Scholar
• Kanno K, Sasaki S, Hirata Y, Ishikawa S, Fushimi K, Nakanishi S, Bichet DG, Marumo F. Urinary excretion of aquaporin-2 in patients with diabetes insipidus. N Engl J Med. 1995;332:1540–45.
   PubMed Web of Science ®Google Scholar
• Ishikawa S, Saito T, Fukagawa A, Higashiyama M, Nakamura T, Kusaka I, Nagasaka S, Honda K, Saito T. Close association of urinary excretion of aquaporin-2 with appropriate and inappropriate arginine vasopressin-dependent antidiuresis in hyponatremia in elderly subjects. J Clin Endocrinol Metab. 2001;86:1665–71.
   PubMed Web of Science ®Google Scholar
• Bielinska K, Radkowski M, Grochowska M, Perlejewski K, Huc T, Jaworska K, Motooka D, Nakamura S, Ufnal M. High salt intake increases plasma trimethylamine N-oxide (TMAO) concentration and produces gut dysbiosis in rats. Nutrition. 2018.
   PubMed Web of Science ®Google Scholar
• Kitai T, Tang WHW. Gut microbiota in cardiovascular disease and heart failure. ( September 2017). 2018;85–91. doi:10.1042/CS20171090.
   Google Scholar
• Tang WHW, Kitai T, Hazen SL. Gut microbiota in cardiovascular health and disease. 2017;1183–96. doi:10.1161/CIRCRESAHA.117.309715.
   Google Scholar