Particulate matter (PM) oxidative potential: Measurement methods and links to PM physicochemical characteristics and health effects

References

• Abrams, J. Y., Weber, R. J., Klein, M., Sarnat, S. E., Chang, H. H., Strickland, M. J., Verma, V., Fang, T., Bates, J. T., Mulholland, J. A., Russell, A. G., & Tolbert, P. E. (2017). Associations between ambient fine particulate oxidativse potential and cardiorespiratory emergency department visits. Environmental Health Perspectives, 125(10), 107008. https://doi.org/10.1289/EHP1545
   PubMed Web of Science ®Google Scholar
• Adetona, O., Zhang, J. J., Hall, D. B., Wang, J.-S., Vena, J. E., & Naeher, L. P. (2013). Occupational exposure to woodsmoke and oxidative stress in wildland firefighters. The Science of the Total Environment, 449, 269–275. https://doi.org/10.1016/j.scitotenv.2013.01.075
   PubMed Web of Science ®Google Scholar
• Agranovski, I., Moustafa, S., & Braddock, R. (2005). Performance of activated carbon loaded fibrous filters on simultaneous removal of particulate and gaseous pollutants. Environmental Technology, 26(7), 757–766. https://doi.org/10.1080/09593332608618516
   PubMed Web of Science ®Google Scholar
• Allen, R. W., & Barn, P. (2020). Individual- and household-level interventions to reduce air pollution exposures and health risks: A review of the recent literature. Current Environmental Health Reports, 7(4), 424–417. https://doi.org/10.1007/s40572-020-00296-z
   PubMedGoogle Scholar
• Andrade, C., Molina, C., Sánchez, L. F., Manzano, C. A., Toro A, R., & Leiva G, M. A. (2021). Exploring the oxidative potential and respiratory deposition of size-segregated particulate matter at an urban site. Journal of South American Earth Sciences, 105, 102957. https://doi.org/10.1016/j.jsames.2020.102957
   Web of Science ®Google Scholar
• Antiñolo, M., Willis, M. D., Zhou, S., & Abbatt, J. P. (2015). Connecting the oxidation of soot to its redox cycling abilities. Nature Communications, 6(1), 1–7. https://doi.org/10.1038/ncomms7812
   Google Scholar
• Atkinson, R. W., Samoli, E., Analitis, A., Fuller, G. W., Green, D. C., Anderson, H. R., Purdie, E., Dunster, C., Aitlhadj, L., Kelly, F. J., & Mudway, I. S. (2016). Short-term associations between particle oxidative potential and daily mortality and hospital admissions in London. International Journal of Hygiene and Environmental Health, 219(6), 566–572. https://doi.org/10.1016/j.ijheh.2016.06.004
   PubMed Web of Science ®Google Scholar
• Bates, J. T., Fang, T., Verma, V., Zeng, L., Weber, R. J., Tolbert, P. E., Abrams, J. Y., Sarnat, S. E., Klein, M., Mulholland, J. A., & Russell, A. G. (2019). Review of acellular assays of ambient particulate matter oxidative potential: Methods and relationships with composition, sources, and health effects. Environmental Science & Technology, 53(8), 4003–4019. https://doi.org/10.1021/acs.est.8b03430
   PubMed Web of Science ®Google Scholar
• Bates, J. T., Weber, R. J., Abrams, J., Verma, V., Fang, T., Klein, M., Strickland, M. J., Sarnat, S. E., Chang, H. H., Mulholland, J. A., Tolbert, P. E., & Russell, A. G. (2015). Reactive oxygen species generation linked to sources of atmospheric particulate matter and cardiorespiratory effects. Environmental Science & Technology, 49(22), 13605–13612. https://doi.org/10.1021/acs.est.5b02967
   PubMed Web of Science ®Google Scholar
• Batterman, S., Du, L., Mentz, G., Mukherjee, B., Parker, E., Godwin, C., Chin, J.-Y., O'Toole, A., Robins, T., Rowe, Z., & Lewis, T. (2012). Particulate matter concentrations in residences: An intervention study evaluating stand-alone filters and air conditioners . Indoor Air, 22(3), 235–252. https://doi.org/10.1111/j.1600-0668.2011.00761.x
   PubMed Web of Science ®Google Scholar
• Bhatnagar, A. (2004). Cardiovascular pathophysiology of environmental pollutants. American Journal of Physiology. Heart and Circulatory Physiology, 286(2), H479–H485. https://doi.org/10.1152/ajpheart.00817.2003
   PubMed Web of Science ®Google Scholar
• Bowe, B., Xie, Y., Li, T., Yan, Y., Xian, H., & Al-Aly, Z. (2018). The 2016 global and national burden of diabetes mellitus attributable to PM2.5 air pollution. The Lancet. Planetary Health, 2(7), e301–e312. https://doi.org/10.1016/S2542-5196(18)30140-2
   PubMedGoogle Scholar
• Brehmer, C., Norris, C., Barkjohn, K. K., Bergin, M. H., Zhang, J., Cui, X., Teng, Y., Zhang, Y., Black, M., Li, Z., Shafer, M., & Schauer, J. J. (2020). The impact of household air cleaners on the oxidative potential of PM2.5 and the role of metals and sources associated with indoor and outdoor exposure. Environmental Research, 181, 108919. https://doi.org/10.1016/j.envres.2019.108919
   PubMed Web of Science ®Google Scholar
• Brehmer, C., Norris, C., Barkjohn, K. K., Bergin, M. H., Zhang, J., Cui, X., Zhang, Y., Black, M., Li, Z., Shafer, M., & Schauer, J. J. (2019). The impact of household air cleaners on the chemical composition and children's exposure to PM2.5 metal sources in suburban Shanghai. Environmental Pollution (Barking, Essex: 1987), 253, 190–198. https://doi.org/10.1016/j.envpol.2019.07.003
   PubMed Web of Science ®Google Scholar
• Brown, D. M., Stone, V., Findlay, P., Macnee, W., & Donaldson, K. (2000). Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components. Occupational and Environmental Medicine, 57(10), 685–691. https://doi.org/10.1136/oem.57.10.685
   PubMed Web of Science ®Google Scholar
• Calas, A., Uzu, G., Martins, J. M., Voisin, D., Spadini, L., Lacroix, T., & Jaffrezo, J.-L. (2017). The importance of simulated lung fluid (SLF) extractions for a more relevant evaluation of the oxidative potential of particulate matter. Scientific Reports, 7(1), 1–12. https://doi.org/10.1038/s41598-017-11979-3
   PubMedGoogle Scholar
• Campbell, S. J., Utinger, B., Lienhard, D. M., Paulson, S. E., Shen, J., Griffiths, P. T., Stell, A. C., & Kalberer, M. (2019). Development of a physiologically relevant online chemical assay to quantify aerosol oxidative potential. Analytical Chemistry, 91(20), 13088–13095. https://doi.org/10.1021/acs.analchem.9b03282
   PubMed Web of Science ®Google Scholar
• Charrier, J. G., Richards-Henderson, N. K., Bein, K. J., McFall, A. S., Wexler, A. S., & Anastasio, C. (2015). Oxidant production from source-oriented particulate matter–Part 1: Oxidative potential using the dithiothreitol (DTT) assay. Atmospheric Chemistry and Physics, 15(5), 2327–2340. https://doi.org/10.5194/acp-15-2327-2015
   Web of Science ®Google Scholar
• Chen, P., Chang, H., Chang, J., & Lin, P. (2012). Aryl hydrocarbon receptor in association with RelA modulates IL-6 expression in non-smoking lung cancer. Oncogene, 31(20), 2555–2565. https://doi.org/10.1038/onc.2011.438
   PubMed Web of Science ®Google Scholar
• Chlebowski, A. C., Garcia, G. R., La Du, J. K., Bisson, W. H., Truong, L., Massey Simonich, S. L., & Tanguay, R. L. (2017). Mechanistic investigations into the developmental toxicity of nitrated and heterocyclic PAHs. Toxicological Sciences: An Official Journal of the Society of Toxicology, 157(1), 246–259. https://doi.org/10.1093/toxsci/kfx035
   PubMed Web of Science ®Google Scholar
• Cho, C.-C., Hsieh, W.-Y., Tsai, C.-H., Chen, C.-Y., Chang, H.-F., & Lin, C.-S. (2018). In vitro and in vivo experimental studies of PM2. 5 on disease progression. International Journal of Environmental Research and Public Health, 15(7), 1380. https://doi.org/10.3390/ijerph15071380
   PubMed Web of Science ®Google Scholar
• Chowdhury, P. H., He, Q., Carmieli, R., Li, C., Rudich, Y., & Pardo, M. (2019). Connecting the oxidative potential of secondary organic aerosols with reactive oxygen species in exposed lung cells. Environmental Science & Technology, 53(23), 13949–13958. https://doi.org/10.1021/acs.est.9b04449
   PubMed Web of Science ®Google Scholar
• Cooper, D. M., & Loxham, M. (2019). Particulate matter and the airway epithelium: The special case of the underground? European Respiratory Review, 28(153), 190066. https://doi.org/10.1183/16000617.0066-2019
   PubMed Web of Science ®Google Scholar
• Crobeddu, B., Aragao-Santiago, L., Bui, L.-C., Boland, S., & Squiban, A. B. (2017). Oxidative potential of particulate matter 2.5 as predictive indicator of cellular stress. Environmental Pollution (Barking, Essex: 1987), 230, 125–133. https://doi.org/10.1016/j.envpol.2017.06.051
   PubMed Web of Science ®Google Scholar
• Cui, X., Li, Z., Teng, Y., Barkjohn, K. K., Norris, C. L., Fang, L., Daniel, G. N., He, L., Lin, L., Wang, Q., Day, D. B., Zhou, X., Hong, J., Gong, J., Li, F., Mo, J., Zhang, Y., Schauer, J. J., Black, M. S., Bergin, M. H., & Zhang, J. (2020). Association between bedroom particulate matter filtration and changes in airway pathophysiology in children with asthma. JAMA Pediatrics, 174(6), 533–542. https://doi.org/10.1001/jamapediatrics.2020.0140
   PubMed Web of Science ®Google Scholar
• Cui, X., Li, F., Xiang, J., Fang, L., Chung, M. K., Day, D. B., Mo, J., Weschler, C. J., Gong, J., He, L., Zhu, D., Lu, C., Han, H., Zhang, Y., & Zhang, J. J. (2018). Cardiopulmonary effects of overnight indoor air filtration in healthy non-smoking adults: A double-blind randomized crossover study. Environment International, 114, 27–36. https://doi.org/10.1016/j.envint.2018.02.010
   PubMed Web of Science ®Google Scholar
• Daher, N., Ruprecht, A., Invernizzi, G., De Marco, C., Miller-Schulze, J., Heo, J. B., Shafer, M. M., Shelton, B. R., Schauer, J. J., & Sioutas, C. (2012). Characterization, sources and redox activity of fine and coarse particulate matter in Milan, Italy. Atmospheric Environment, 49, 130–141. https://doi.org/10.1016/j.atmosenv.2011.12.011
   Web of Science ®Google Scholar
• Daher, N., Saliba, N. A., Shihadeh, A. L., Jaafar, M., Baalbaki, R., Shafer, M. M., Schauer, J. J., & Sioutas, C. (2014). Oxidative potential and chemical speciation of size-resolved particulate matter (PM) at near-freeway and urban background sites in the greater Beirut area. Science of the Total Environment, 470-471, 417–426. https://doi.org/10.1016/j.scitotenv.2013.09.104
   PubMed Web of Science ®Google Scholar
• Dastoorpoor, M., Riahi, A., Yazdaninejhad, H., Borsi, S. H., Khanjani, N., Khodadadi, N., Mohammadi, M. J., & Aghababaeian, H. (2021). Exposure to particulate matter and carbon monoxide and cause-specific Cardiovascular-Respiratory disease mortality in Ahvaz. Toxin Reviews, 40(4), 1362–1311. https://doi.org/10.1080/15569543.2020.1716256
   Web of Science ®Google Scholar
• Delfino, R. J., Quintana, P. J., Floro, J., Gastañaga, V. M., Samimi, B. S., Kleinman, M. T., Liu, L. S., Bufalino, C., Wu, C.-F., & McLaren, C. E. (2004). Association of FEV1 in asthmatic children with personal and microenvironmental exposure to airborne particulate matter. Environmental Health Perspectives, 112(8), 932–941. https://doi.org/10.1289/ehp.6815
   PubMed Web of Science ®Google Scholar
• Delfino, R. J., Staimer, N., Tjoa, T., Gillen, D., Kleinman, M. T., Sioutas, C., & Cooper, D. (2008). Personal and ambient air pollution exposures and lung function decrements in children with asthma. Environmental Health Perspectives, 116(4), 550–558. https://doi.org/10.1289/ehp.10911
   PubMed Web of Science ®Google Scholar
• Delfino, R. J., Staimer, N., Tjoa, T., Gillen, D. L., Schauer, J. J., & Shafer, M. M. (2013). Airway inflammation and oxidative potential of air pollutant particles in a pediatric asthma panel. Journal of Exposure Science & Environmental Epidemiology, 23(5), 466–473. https://doi.org/10.1038/jes.2013.25
   PubMed Web of Science ®Google Scholar
• Elder, A., & Oberdörster, G. (2006). Translocation and effects of ultrafine particles outside of the lung. Clinics in Occupational and Environmental Medicine, 5, 785–796. https://doi.org/10.1016/j.coem.2006.07.003
   PubMedGoogle Scholar
• Fang, T., Lakey, P. S., Weber, R. J., & Shiraiwa, M. (2019). Oxidative potential of particulate matter and generation of reactive oxygen species in epithelial lining fluid. Environmental Science & Technology, 53(21), 12784–12792. https://doi.org/10.1021/acs.est.9b03823
   PubMed Web of Science ®Google Scholar
• Fang, T., Verma, V., Bates, J., Abrams, J., Klein, M., Strickland, M., Sarnat, S., Chang, H., Mulholland, J., Tolbert, P., Russell, A. G., & Weber, R. J. (2016). Oxidative potential of ambient water-soluble PM 2.5 measured by dithiothreitol (DTT) and ascorbic acid (AA) assays in the southeastern United States: Contrasts in sources and health associations. Atmospheric Chemistry and Physics, 16(6), 3865–3879. https://doi.org/10.5194/acp-16-3865-2016
   Web of Science ®Google Scholar
• Fang, T., Zeng, L., Gao, D., Verma, V., Stefaniak, A. B., & Weber, R. J. (2017). Ambient size distributions and lung deposition of aerosol dithiothreitol-measured oxidative potential: Contrast between soluble and insoluble particles. Environmental Science & Technology, 51(12), 6802–6811. https://doi.org/10.1021/acs.est.7b01536
   PubMed Web of Science ®Google Scholar
• Farrow, A., Taylor, H., & Golding, J. (1997). Time spent in the home by different family members. Environmental Technology, 18(6), 605–613. https://doi.org/10.1080/09593331808616578
   Web of Science ®Google Scholar
• Feng, S., Gao, D., Liao, F., Zhou, F., & Wang, X. (2016). The health effects of ambient PM2.5 and potential mechanisms. Ecotoxicology and Environmental Safety, 128, 67–74. https://doi.org/10.1016/j.ecoenv.2016.01.030
   PubMed Web of Science ®Google Scholar
• Forman, H. J., & Finch, C. E. (2018). A critical review of assays for hazardous components of air pollution. Free Radical Biology & Medicine, 117, 202–217. https://doi.org/10.1016/j.freeradbiomed.2018.01.030
   PubMed Web of Science ®Google Scholar
• Fujitani, Y., Furuyama, A., Tanabe, K., & Hirano, S. (2017). Comparison of oxidative abilities of PM2. 5 collected at traffic and residential sites in Japan. Contribution of transition metals and primary and secondary aerosols. Aerosol and Air Quality Research, 17(2), 574–587. https://doi.org/10.4209/aaqr.2016.07.0291
   Web of Science ®Google Scholar
• Fuller, S., Wragg, F., Nutter, J., & Kalberer, M. (2014). Comparison of on-line and off-line methods to quantify reactive oxygen species (ROS) in atmospheric aerosols. Atmospheric Environment, 92, 97–103. https://doi.org/10.1016/j.atmosenv.2014.04.006
   Web of Science ®Google Scholar
• Goldsmith, C.-A., Frevert, C., Imrich, A., Sioutas, C., & Kobzik, L. (1997). Alveolar macrophage interaction with air pollution particulates. Environmental Health Perspectives, 105, 1191–1195. https://doi.org/10.2307/3433531
   PubMed Web of Science ®Google Scholar
• Guo, H., Jin, L., & Huang, S. (2020). Effect of PM characterization on PM oxidative potential by acellular assays: A review. Reviews on Environmental Health, 35(4), 461–470. https://doi.org/10.1515/reveh-2020-0003
   PubMed Web of Science ®Google Scholar
• Guo, H-b., Li, M., Lyu, Y., Cheng, T-t., Xv, JJ., & Li, X. (2019). Size-resolved particle oxidative potential in the office, laboratory, and home: Evidence for the importance of water-soluble transition metals. Environmental Pollution (Barking, Essex: 1987), 246, 704–709. https://doi.org/10.1016/j.envpol.2018.12.094
   PubMed Web of Science ®Google Scholar
• Gutiérrez-Vázquez, C., & Quintana, F. J. (2018). Regulation of the immune response by the aryl hydrocarbon receptor. Immunity, 48(1), 19–33. https://doi.org/10.1016/j.immuni.2017.12.012
   PubMed Web of Science ®Google Scholar
• Harrison, R. M., & Yin, J. (2000). Particulate matter in the atmosphere: Which particle properties are important for its effects on health? Science of the Total Environment, 249(1-3), 85–101. https://doi.org/10.1016/S0048-9697(99)00513-6
   PubMed Web of Science ®Google Scholar
• Hayes, R. B., Lim, C., Zhang, Y., Cromar, K., Shao, Y., Reynolds, H. R., Silverman, D. T., Jones, R. R., Park, Y., Jerrett, M., Ahn, J., & Thurston, G. D. (2020). PM2.5 air pollution and cause-specific cardiovascular disease mortality. International Journal of Epidemiology, 49(1), 25–35. https://doi.org/10.1093/ije/dyz114
   PubMed Web of Science ®Google Scholar
• He, L., Cui, X., Li, Z., Teng, Y., Barkjohn, K. K., Norris, C., Fang, L., Lin, L., Wang, Q., Zhou, X., Hong, J., Li, F., Zhang, Y., Schauer, J. J., Black, M., Bergin, M. H., & Zhang, J. J. (2020a). Malondialdehyde in nasal fluid: A biomarker for monitoring asthma control in relation to air pollution exposure. Environmental Science & Technology, 54(18), 11405–11413. https://doi.org/10.1021/acs.est.0c02558
   PubMed Web of Science ®Google Scholar
• He, L., Cui, X., Xia, Q., Li, F., Mo, J., Gong, J., Zhang, Y., & Zhang, J. J. (2020b). Effects of personal air pollutant exposure on oxidative stress: Potential confounding by natural variation in melatonin levels. International Journal of Hygiene and Environmental Health, 223(1), 116–123. https://doi.org/10.1016/j.ijheh.2019.09.012
   PubMed Web of Science ®Google Scholar
• Hellack, B., Yang, A., Cassee, F. R., Janssen, N. A., Schins, R. P., & Kuhlbusch, T. A. (2014). Intrinsic hydroxyl radical generation measurements directly from sampled filters as a metric for the oxidative potential of ambient particulate matter. Journal of Aerosol Science, 72, 47–55. https://doi.org/10.1016/j.jaerosci.2014.02.003
   Web of Science ®Google Scholar
• He, L., Norris, C., Cui, X., Li, Z., Barkjohn, K. K., Brehmer, C., Teng, Y., Fang, L., Lin, L., Wang, Q., Zhou, X., Hong, J., Li, F., Zhang, Y., Schauer, J. J., Black, M., Bergin, M. H., & Zhang, J. J. (2021). Personal exposure to PM2.5 oxidative potential in association with pulmonary pathophysiologic outcomes in children with asthma. Environmental Science & Technology, 55(5), 3101–3111. https://doi.org/10.1021/acs.est.0c06114
   PubMed Web of Science ®Google Scholar
• Hong, Z., Guo, Z., Zhang, R., Xu, J., Dong, W., Zhuang, G., & Deng, C. (2016). Airborne fine particulate matter induces oxidative stress and inflammation in human nasal epithelial cells. The Tohoku Journal of Experimental Medicine, 239(2), 117–125. https://doi.org/10.1620/tjem.239.117
   PubMed Web of Science ®Google Scholar
• Hu, X., He, L., Zhang, J., Qiu, X., Zhang, Y., Mo, J., Day, D. B., Xiang, J., & Gong, J. (2020). Inflammatory and oxidative stress responses of healthy adults to changes in personal air pollutant exposure. Environmental Pollution (Barking, Essex: 1987), 263 (Pt A), 114503. https://doi.org/10.1016/j.envpol.2020.114503
   PubMedGoogle Scholar
• Hu, S., Polidori, A., Arhami, M., Shafer, M., Schauer, J., Cho, A., & Sioutas, C. (2008). Redox activity and chemical speciation of size fractioned PM in the communities of the Los Angeles-Long Beach harbor. Atmospheric Chemistry and Physics, 8(21), 6439–6451. https://doi.org/10.5194/acp-8-6439-2008
   Web of Science ®Google Scholar
• Imrich, A., Ning, Y., & Kobzik, L. (1999). Intracellular oxidant production and cytokine responses in lung macrophages: Evaluation of fluorescent probes. Journal of Leukocyte Biology, 65(4), 499–507. https://doi.org/10.1002/jlb.65.4.499
   PubMed Web of Science ®Google Scholar
• Janssen, N. A., Strak, M., Yang, A., Hellack, B., Kelly, F. J., Kuhlbusch, T. A., Harrison, R. M., Brunekreef, B., Cassee, F. R., Steenhof, M., & Hoek, G. (2015). Associations between three specific a-cellular measures of the oxidative potential of particulate matter and markers of acute airway and nasal inflammation in healthy volunteers. Occupational and Environmental Medicine, 72(1), 49–56. https://doi.org/10.1136/oemed-2014-102303
   PubMed Web of Science ®Google Scholar
• Jia, Y.-Y., Wang, Q., & Liu, T. (2017). Toxicity research of PM2.5 compositions in vitro. International Journal of Environmental Research and Public Health, 14(3), 232. https://doi.org/10.3390/ijerph14030232
   PubMed Web of Science ®Google Scholar
• Jiang, H., Jang, M., Sabo-Attwood, T., & Robinson, S. E. (2016). Oxidative potential of secondary organic aerosols produced from photooxidation of different hydrocarbons using outdoor chamber under ambient sunlight. Atmospheric Environment, 131, 382–389. https://doi.org/10.1016/j.atmosenv.2016.02.016
   Web of Science ®Google Scholar
• Kalyanaraman, B., Darley-Usmar, V., Davies, K. J., Dennery, P. A., Forman, H. J., Grisham, M. B., Mann, G. E., Moore, K., Roberts, L. J., II,., & Ischiropoulos, H. (2012). Measuring reactive oxygen and nitrogen species with fluorescent probes: Challenges and limitations. Free Radical Biology & Medicine, 52(1), 1–6. https://doi.org/10.1016/j.freeradbiomed.2011.09.030
   PubMed Web of Science ®Google Scholar
• Ke, Y., Huang, L., Xia, J., Xu, X., Liu, H., & Li, Y. R. (2016). Comparative study of oxidative stress biomarkers in urine of cooks exposed to three types of cooking-related particles. Toxicology Letters., 255, 36–42. https://doi.org/10.1016/j.toxlet.2016.05.017
   PubMed Web of Science ®Google Scholar
• Kelly, F. J., & Fussell, J. C. (2012). Size, source and chemical composition as determinants of toxicity attributable to ambient particulate matter. Atmospheric Environment, 60, 504–526. https://doi.org/10.1016/j.atmosenv.2012.06.039
   Web of Science ®Google Scholar
• Klein, F., Farren, N. J., Bozzetti, C., Daellenbach, K. R., Kilic, D., Kumar, N. K., Pieber, S. M., Slowik, J. G., Tuthill, R. N., Hamilton, J. F., Baltensperger, U., Prevot, A. S. H., & Haddad, I. E. (2016). Indoor terpene emissions from cooking with herbs and pepper and their secondary organic aerosol production potential. Scientific Reports, 6, 36623. https://doi.org/10.1038/srep36623
   PubMed Web of Science ®Google Scholar
• Kuehn, B. M. (2014). WHO: More than 7 million air pollution deaths each year. Jama, 311(15), 1486–1486. https://doi.org/10.1001/jama.2014.4031
   PubMed Web of Science ®Google Scholar
• Landreman, A. P., Shafer, M. M., Hemming, J. C., Hannigan, M. P., & Schauer, J. J. (2008). A macrophage-based method for the assessment of the reactive oxygen species (ROS) activity of atmospheric particulate matter (PM) and application to routine (daily-24 h) aerosol monitoring studies. Aerosol Science and Technology, 42(11), 946–957. https://doi.org/10.1080/02786820802363819
   Web of Science ®Google Scholar
• Lee, S., Lee, W., Kim, D., Kim, E., Myung, W., Kim, S.-Y., & Kim, H. (2019). Short-term PM2. 5 exposure and emergency hospital admissions for mental disease. Environmental Research, 171, 313–320. https://doi.org/10.1016/j.envres.2019.01.036
   PubMed Web of Science ®Google Scholar
• Lelieveld, J., Evans, J. S., Fnais, M., Giannadaki, D., & Pozzer, A. (2015). The contribution of outdoor air pollution sources to premature mortality on a global scale. Nature, 525(7569), 367–371. https://doi.org/10.1038/nature15371
   PubMed Web of Science ®Google Scholar
• Libalova, H., Milcova, A., Cervena, T., Vrbova, K., Rossnerova, A., Novakova, Z., Topinka, J., & Rossner, P. (2018). Kinetics of ROS generation induced by polycyclic aromatic hydrocarbons and organic extracts from ambient air particulate matter in model human lung cell lines. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 827, 50–58. https://doi.org/10.1016/j.mrgentox.2018.01.006
   PubMed Web of Science ®Google Scholar
• Liu, Q., Baumgartner, J., Zhang, Y., Liu, Y., Sun, Y., & Zhang, M. (2014). Oxidative potential and inflammatory impacts of source apportioned ambient air pollution in Beijing. Environmental Science & Technology, 48(21), 12920–12929. https://doi.org/10.1021/es5029876
   PubMed Web of Science ®Google Scholar
• Lu, Y., Su, S., Jin, W., Wang, B., Li, N., Shen, H., Li, W., Huang, Y., Chen, H., Zhang, Y., Chen, Y., Lin, N., Wang, X., & Tao, S. (2014). Characteristics and cellular effects of ambient particulate matter from Beijing. Environmental Pollution (Barking, Essex: 1987), 191, 63–69. https://doi.org/10.1016/j.envpol.2014.04.008
   PubMed Web of Science ®Google Scholar
• Lyu, Y., Guo, H., Cheng, T., & Li, X. (2018). Particle size distributions of oxidative potential of lung-deposited particles: Assessing contributions from quinones and water-soluble metals. Environmental Science & Technology, 52(11), 6592–6600. https://doi.org/10.1021/acs.est.7b06686
   PubMed Web of Science ®Google Scholar
• Ma, Y., Cheng, Y., Qiu, X., Cao, G., Fang, Y., Wang, J., Zhu, T., Yu, J., & Hu, D. (2018). Sources and oxidative potential of water-soluble humic-like substances (HULIS WS) in fine particulate matter (PM 2.5) in Beijing. Atmospheric Chemistry and Physics, 18(8), 5607–5617. https://doi.org/10.5194/acp-18-5607-2018
   Web of Science ®Google Scholar
• Maikawa, C. L., Weichenthal, S., Wheeler, A. J., Dobbin, N. A., Smargiassi, A., Evans, G., Liu, L., Goldberg, M. S., & Pollitt, K. J. G. (2016). Particulate oxidative burden as a predictor of exhaled nitric oxide in children with asthma. Environmental Health Perspectives, 124(10), 1616–1622. https://doi.org/10.1289/EHP175
   PubMed Web of Science ®Google Scholar
• Massimi, L., Ristorini, M., Simonetti, G., Frezzini, M. A., Astolfi, M. L., & Canepari, S. (2020). Spatial mapping and size distribution of oxidative potential of particulate matter released by spatially disaggregated sources. Environmental Pollution (Barking, Essex: 1987), 266(Pt 3), 115271. https://doi.org/10.1016/j.envpol.2020.115271
   PubMedGoogle Scholar
• McGuinn, L. A., Schneider, A., McGarrah, R. W., Ward-Caviness, C., Neas, L. M., Di, Q., Schwartz, J., Hauser, E. R., Kraus, W. E., Cascio, W. E., Diaz-Sanchez, D., & Devlin, R. B. (2019). Association of long-term PM2.5 exposure with traditional and novel lipid measures related to cardiovascular disease risk. Environment International, 122, 193–200. https://doi.org/10.1016/j.envint.2018.11.001
   PubMed Web of Science ®Google Scholar
• Momtazan, M., Geravandi, S., Rastegarimehr, B., Valipour, A., Ranjbarzadeh, A., Yari, A. R., Dobaradaran, S., Bostan, H., Farhadi, M., Darabi, F., Khaniabadi, Y. O., & Mohammadi, M. J. (2019). An investigation of particulate matter and relevant cardiovascular risks in Abadan and Khorramshahr in 2014–2016. Toxin Reviews, 38(4), 290–297. https://doi.org/10.1080/15569543.2018.1463266
   Web of Science ®Google Scholar
• Ng, C. F. S., Hashizume, M., Obase, Y., Doi, M., Tamura, K., Tomari, S., Kawano, T., Fukushima, C., Matsuse, H., Chung, Y., Kim, Y., Kunimitsu, K., Kohno, S., & Mukae, H. (2019). Associations of chemical composition and sources of PM2.5 with lung function of severe asthmatic adults in a low air pollution environment of urban Nagasaki, Japan. Environmental Pollution (Barking, Essex: 1987), 252(Pt A), 599–606. https://doi.org/10.1016/j.envpol.2019.05.117
   PubMedGoogle Scholar
• Øvrevik, J. (2019). Oxidative potential versus biological effects: A review on the relevance of cell-free/abiotic assays as predictors of toxicity from airborne particulate matter. International Journal of Molecular Sciences, 20(19), 4772. https://doi.org/10.3390/ijms20194772
   PubMed Web of Science ®Google Scholar
• Pant, P., Baker, S. J., Shukla, A., Maikawa, C., Pollitt, K. J. G., & Harrison, R. M. (2015). The PM10 fraction of road dust in the UK and India: Characterization, source profiles and oxidative potential. Science of the Total Environment, 530-531, 445–452. https://doi.org/10.1016/j.scitotenv.2015.05.084
   PubMed Web of Science ®Google Scholar
• Park, M., Joo, H. S., Lee, K., Jang, M., Kim, S. D., Kim, I., Borlaza, L. J. S., Lim, H., Shin, H., Chung, K. H., Choi, Y.-H., Park, S. G., Bae, M.-S., Lee, J., Song, H., & Park, K. (2018). Differential toxicities of fine particulate matters from various sources. Scientific Reports, 8(1), 1–11. https://doi.org/10.1038/s41598-018-35398-0
   PubMedGoogle Scholar
• Perrone, M. G., Zhou, J., Malandrino, M., Sangiorgi, G., Rizzi, C., Ferrero, L., Dommen, J., & Bolzacchini, E. (2016). PM chemical composition and oxidative potential of the soluble fraction of particles at two sites in the urban area of Milan, Northern Italy. Atmospheric Environment, 128, 104–113. https://doi.org/10.1016/j.atmosenv.2015.12.040
   Web of Science ®Google Scholar
• Pietrogrande, M. C., Russo, M., & Zagatti, E. (2019). Review of PM oxidative potential measured with acellular assays in urban and rural sites across Italy. Atmosphere, 10, 626. https://doi.org/10.3390/atmos10100626
   Web of Science ®Google Scholar
• Podechard, N., Lecureur, V., Le Ferrec, E., Guenon, I., Sparfel, L., Gilot, D., Gordon, J. R., Lagente, V., & Fardel, O. (2008). Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation. Toxicology Letters, 177(2), 130–137. https://doi.org/10.1016/j.toxlet.2008.01.006
   PubMed Web of Science ®Google Scholar
• Polidori, A., Turpin, B., Meng, Q. Y., Lee, J. H., Weisel, C., Morandi, M., Colome, S., Stock, T., Winer, A., Zhang, J., Kwon, J., Alimokhtari, S., Shendell, D., Jones, J., Farrar, C., & Maberti, S. (2006). Fine organic particulate matter dominates indoor-generated PM2.5 in RIOPA homes. Journal of Exposure Science & Environmental Epidemiology, 16(4), 321–331. https://doi.org/10.1038/sj.jes.7500476
   PubMed Web of Science ®Google Scholar
• Puthussery, J. V., Singh, A., Rai, P., Bhattu, D., Kumar, V., Vats, P., Furger, M., Rastogi, N., Slowik, J. G., Ganguly, D., Prevot, A. S. H., Tripathi, S. N., & Verma, V. (2020). Real-time measurements of PM2.5 oxidative potential using a dithiothreitol assay in Delhi, India. Environmental Science & Technology Letters, 7(7), 504–510. https://doi.org/10.1021/acs.estlett.0c00342
   Web of Science ®Google Scholar
• Rich, D. Q., Liu, K., Zhang, J., Thurston, S. W., Stevens, T. P., Pan, Y., Kane, C., Weinberger, B., Ohman-Strickland, P., Woodruff, T. J., Duan, X., Assibey-Mensah, V., & Zhang, J. (2015). Differences in birth weight associated with the 2008 Beijing Olympics air pollution reduction: Results from a natural experiment. Environmental Health Perspectives, 123(9), 880–887. https://doi.org/10.1289/ehp.1408795
   PubMed Web of Science ®Google Scholar
• Roberts, S., Arseneault, L., Barratt, B., Beevers, S., Danese, A., Odgers, C. L., Moffitt, T. E., Reuben, A., Kelly, F. J., & Fisher, H. L. (2019). Exploration of NO2 and PM2.5 air pollution and mental health problems using high-resolution data in London-based children from a UK longitudinal cohort study. Psychiatry Research, 272, 8–17. https://doi.org/10.1016/j.psychres.2018.12.050
   PubMed Web of Science ®Google Scholar
• Robinson, D. L. (2017). Composition and oxidative potential of PM2.5 pollution and health. Journal of Thoracic Disease, 9(3), 444–447. https://doi.org/10.21037/jtd.2017.03.92
   PubMed Web of Science ®Google Scholar
• Rogula-Kozłowska, W. (2016). Size-segregated urban particulate matter: Mass closure, chemical composition, and primary and secondary matter content. Air Quality, Atmosphere, & Health, 9, 533–550. https://doi.org/10.1007/s11869-015-0359-y
   PubMed Web of Science ®Google Scholar
• Saffari, A., Daher, N., Shafer, M. M., Schauer, J. J., & Sioutas, C. (2013). Seasonal and spatial variation in reactive oxygen species activity of quasi-ultrafine particles (PM0.25) in the Los Angeles metropolitan area and its association with chemical composition. Atmospheric Environment, 79, 566–575. https://doi.org/10.1016/j.atmosenv.2013.07.058
   Web of Science ®Google Scholar
• Sarnat, S. E., Chang, H. H., & Weber, R. J. (2016). Ambient PM2.5 and health: Does PM2.5 oxidative potential play a role? American Journal of Respiratory and Critical Care Medicine, 194(5), 530–531. https://doi.org/10.1164/rccm.201603-0589ED
   PubMed Web of Science ®Google Scholar
• Schlesinger, R., Kunzli, N., Hidy, G., Gotschi, T., & Jerrett, M. (2006). The health relevance of ambient particulate matter characteristics: Coherence of toxicological and epidemiological inferences. Inhalation Toxicology, 18(2), 95–125. https://doi.org/10.1080/08958370500306016
   PubMed Web of Science ®Google Scholar
• See, S., & Balasubramanian, R. (2006). Risk assessment of exposure to indoor aerosols associated with Chinese cooking. Environmental Research, 102(2), 197–204. https://doi.org/10.1016/j.envres.2005.12.013
   PubMed Web of Science ®Google Scholar
• Shafer, M. M., Perkins, D. A., Antkiewicz, D. S., Stone, E. A., Quraishi, T. A., & Schauer, J. J. (2010). Reactive oxygen species activity and chemical speciation of size-fractionated atmospheric particulate matter from Lahore, Pakistan: An important role for transition metals. Journal of Environmental Monitoring: JEM, 12(3), 704–715. https://doi.org/10.1039/b915008k
   PubMedGoogle Scholar
• Shen, H., Barakat, A., & Anastasio, C. (2011). Generation of hydrogen peroxide from San Joaquin Valley particles in a cell-free solution. Atmospheric Chemistry and Physics, 11(2), 753–765. https://doi.org/10.5194/acp-11-753-2011
   Web of Science ®Google Scholar
• Shi, T., Schins, R. P., Knaapen, A. M., Kuhlbusch, T., Pitz, M., Heinrich, J., & Borm, P. J. (2003). Hydroxyl radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition. Journal of Environmental Monitoring: JEM, 5(4), 550–556. https://doi.org/10.1039/b303928p
   PubMedGoogle Scholar
• Shirmohammadi, F., Wang, D., Hasheminassab, S., Verma, V., Schauer, J. J., Shafer, M. M., & Sioutas, C. (2017). Oxidative potential of on-road fine particulate matter (PM2. 5) measured on major freeways of Los Angeles, CA, and a 10-year comparison with earlier roadside studies. Atmospheric Environment, 148, 102–114. https://doi.org/10.1016/j.atmosenv.2016.10.042
   Web of Science ®Google Scholar
• Simonetti, G., Conte, E., Perrino, C., & Canepari, S. (2018). Oxidative potential of size-segregated PM in an urban and an industrial area of Italy. Atmospheric Environment, 187, 292–300. https://doi.org/10.1016/j.atmosenv.2018.05.051
   Web of Science ®Google Scholar
• Sinharay, R., Gong, J., Barratt, B., Ohman-Strickland, P., Ernst, S., Kelly, F. J., Zhang, J. J., Collins, P., Cullinan, P., & Chung, K. F. (2018). Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: A randomised, crossover study. The Lancet, 391(10118), 339–349. https://doi.org/10.1016/S0140-6736(17)32643-0
   PubMed Web of Science ®Google Scholar
• Smargiassi, A., Goldberg, M. S., Wheeler, A. J., Plante, C., Valois, M.-F., Mallach, G., Kauri, L. M., Shutt, R., Bartlett, S., Raphoz, M., & Liu, L. (2014). Associations between personal exposure to air pollutants and lung function tests and cardiovascular indices among children with asthma living near an industrial complex and petroleum refineries. Environmental Research, 132, 38–45. https://doi.org/10.1016/j.envres.2014.03.030
   PubMed Web of Science ®Google Scholar
• Soukup, J. M., Ghio, A. J., & Becker, S. (2000). Soluble components of Utah Valley particulate pollution alter alveolar macrophage function in vivo and in vitro. Inhalation Toxicology, 12(5), 401–414. https://doi.org/10.1080/089583700196112
   PubMed Web of Science ®Google Scholar
• Steenhof, M., Gosens, I., Strak, M., Godri, K. J., Hoek, G., Cassee, F. R., Mudway, I. S., Kelly, F. J., Harrison, R. M., Lebret, E., Brunekreef, B., Janssen, N. A., & Pieters, R. H. (2011). In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential-the RAPTES project. Particle and Fibre Toxicology, 8(1), 15. https://doi.org/10.1186/1743-8977-8-26
   PubMedGoogle Scholar
• Stowell, J. D., Geng, G., Saikawa, E., Chang, H. H., Fu, J., Yang, C.-E., Zhu, Q., Liu, Y., & Strickland, M. J. (2019). Associations of wildfire smoke PM2.5 exposure with cardiorespiratory events in Colorado 2011–2014. Environment International, 133(Pt A), 105151. https://doi.org/10.1016/j.envint.2019.105151
   PubMedGoogle Scholar
• Tacu, I., Kokalari, I., Abollino, O., Albrecht, C., Malandrino, M., Ferretti, A. M., Schins, R. P., & Fenoglio, I. (2021). Mechanistic insights into the role of iron, copper, and carbonaceous component on the oxidative potential of ultrafine particulate matter. Chemical Research in Toxicology, 34(3), 767–779. https://doi.org/10.1021/acs.chemrestox.0c00399
   PubMed Web of Science ®Google Scholar
• Tong, H., Lakey, P. S. J., Arangio, A. M., Socorro, J., Shen, F., Lucas, K., Brune, W. H., Pöschl, U., & Shiraiwa, M. (2018). Reactive oxygen species formed by secondary organic aerosols in water and surrogate lung fluid. Environmental Science & Technology, 52(20), 11642–11651. https://doi.org/10.1021/acs.est.8b03695
   PubMed Web of Science ®Google Scholar
• Toriba, A., Homma, C., Kita, M., Uozaki, W., Boongla, Y., Orakij, W., Tang, N., Kameda, T., & Hayakawa, K. (2016). Simultaneous determination of polycyclic aromatic hydrocarbon quinones by gas chromatography-tandem mass spectrometry, following a one-pot reductive trimethylsilyl derivatization. Journal of Chromatography. A, 1459, 89–100. https://doi.org/10.1016/j.chroma.2016.06.034
   PubMed Web of Science ®Google Scholar
• Totlandsdal, A. I., Låg, M., Lilleaas, E., Cassee, F., & Schwarze, P. (2015). Differential proinflammatory responses induced by diesel exhaust particles with contrasting PAH and metal content. Environmental Toxicology, 30(2), 188–196. https://doi.org/10.1002/tox.21884
   PubMed Web of Science ®Google Scholar
• Trenga, C. A., Sullivan, J. H., Schildcrout, J. S., Shepherd, K. P., Shapiro, G. G., Liu, L.-J. S., Kaufman, J. D., & Koenig, J. Q. (2006). Effect of particulate air pollution on lung function in adult and pediatric subjects in a Seattle panel study. Chest, 129(6), 1614–1622. https://doi.org/10.1378/chest.129.6.1614
   PubMed Web of Science ®Google Scholar
• Tuet, W. Y., Fok, S., Verma, V., Rodriguez, M. S. T., Grosberg, A., Champion, J. A., & Ng, N. L. (2016). Dose-dependent intracellular reactive oxygen and nitrogen species (ROS/RNS) production from particulate matter exposure: Comparison to oxidative potential and chemical composition. Atmospheric Environment, 144, 335–344. https://doi.org/10.1016/j.atmosenv.2016.09.005
   Web of Science ®Google Scholar
• Unosson, J., Kabéle, M., Boman, C., Nyström, R., Sadiktsis, I., Westerholm, R., Mudway, I. S., Purdie, E., Raftis, J., Miller, M. R., Mills, N. L., Newby, D. E., Blomberg, A., Sandström, T., & Bosson, J. A. (2021). Acute cardiovascular effects of controlled exposure to dilute Petrodiesel and biodiesel exhaust in healthy volunteers: A crossover study. Particle and Fibre Toxicology, 18(1), 14. https://doi.org/10.1186/s12989-021-00412-3
   PubMed Web of Science ®Google Scholar
• Venkatachari, P., & Hopke, P. K. (2008). Development and evaluation of a particle-bound reactive oxygen species generator. Journal of Aerosol Science, 39(2), 168–174. https://doi.org/10.1016/j.jaerosci.2007.11.003
   Web of Science ®Google Scholar
• Verma, V., Fang, T., Guo, H., King, L., Bates, J., Peltier, R., Edgerton, E., Russell, A., & Weber, R. (2014). Reactive oxygen species associated with water-soluble PM 2.5 in the southeastern United States: Spatiotemporal trends and source apportionment. Atmospheric Chemistry and Physics, 14(23), 12915–12930. https://doi.org/10.5194/acp-14-12915-2014
   Web of Science ®Google Scholar
• Verma, V., Fang, T., Xu, L., Peltier, R. E., Russell, A. G., Ng, N. L., & Weber, R. J. (2015). Organic aerosols associated with the generation of reactive oxygen species (ROS) by water-soluble PM2.5. Environmental Science & Technology, 49(7), 4646–4656. https://doi.org/10.1021/es505577w
   PubMed Web of Science ®Google Scholar
• Verma, V., Polidori, A., Schauer, J. J., Shafer, M. M., Cassee, F. R., & Sioutas, C. (2009). Physicochemical and toxicological profiles of particulate matter in Los Angeles during the October 2007 southern California wildfires. Environmental Science & Technology, 43(3), 954–960. https://doi.org/10.1021/es8021667
   PubMed Web of Science ®Google Scholar
• Verma, V., Rico-Martinez, R., Kotra, N., King, L., Liu, J., Snell, T. W., & Weber, R. J. (2012). Contribution of water-soluble and insoluble components and their hydrophobic/hydrophilic subfractions to the reactive oxygen species-generating potential of fine ambient aerosols. Environmental Science & Technology, 46(20), 11384–11392. https://doi.org/10.1021/es302484r
   PubMed Web of Science ®Google Scholar
• Wang, Y., Kim, H., & Paulson, S. E. (2011). Hydrogen peroxide generation from α-and β-pinene and toluene secondary organic aerosols. Atmospheric Environment, 45(18), 3149–3156. https://doi.org/10.1016/j.atmosenv.2011.02.060
   Web of Science ®Google Scholar
• Wang, L., Luo, D., Liu, X., Zhu, J., Wang, F., Li, B., & Li, L. (2021). Effects of PM2. 5 exposure on reproductive system and its mechanisms. Chemosphere, 264, 128436. https://doi.org/10.1016/j.chemosphere.2020.128436
   PubMed Web of Science ®Google Scholar
• Weichenthal, S. A., Lavigne, E., Evans, G. J., Godri Pollitt, K. J., & Burnett, R. T. (2016b). Fine particulate matter and emergency room visits for respiratory illness. Effect modification by oxidative potential. American Journal of Respiratory and Critical Care Medicine, 194(5), 577–586. https://doi.org/10.1164/rccm.201512-2434OC
   PubMed Web of Science ®Google Scholar
• Weichenthal, S., Lavigne, E., Evans, G., Pollitt, K., & Burnett, R. T. (2016a). Ambient PM 2.5 and risk of emergency room visits for myocardial infarction: Impact of regional PM 2.5 oxidative potential: A case-crossover study. Environmental Health, 15(1), 1–9. https://doi.org/10.1186/s12940-016-0129-9
   PubMedGoogle Scholar
• Wilson, M. R., Lightbody, J. H., Donaldson, K., Sales, J., & Stone, V. (2002). Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicology and Applied Pharmacology, 184(3), 172–179. https://doi.org/10.1006/taap.2002.9501
   PubMed Web of Science ®Google Scholar
• Wragg, F. P., Fuller, S. J., Freshwater, R., Green, D. C., Kelly, F. J., & Kalberer, M. (2016). An automated online instrument to quantify aerosol-bound reactive oxygen species (ROS) for ambient measurement and health-relevant aerosol studies. Atmospheric Measurement Techniques, 9(10), 4891–4900. https://doi.org/10.5194/amt-9-4891-2016
   Web of Science ®Google Scholar
• Xia, X., Chan, K. H., Lam, K. B. H., Qiu, H., Li, Z., Yim, S. H. L., & Ho, K.-F. (2021). Effectiveness of indoor air purification intervention in improving cardiovascular health: A systematic review and meta-analysis of randomized controlled trials. The Science of the Total Environment, 789, 147882. https://doi.org/10.1016/j.scitotenv.2021.147882
   PubMed Web of Science ®Google Scholar
• Xing, Y.-F., Xu, Y.-H., Shi, M.-H., & Lian, Y.-X. (2016). The impact of PM2. 5 on the human respiratory system. Journal of Thoracic Disease, 8(1), E69–E74. https://doi.org/10.3978/j.issn.2072-1439.2016.01.19
   PubMed Web of Science ®Google Scholar
• Xiong, Q., Yu, H., Wang, R., Wei, J., & Verma, V. (2017). Rethinking dithiothreitol-based particulate matter oxidative potential: Measuring dithiothreitol consumption versus reactive oxygen species generation. Environmental Science & Technology, 51(11), 6507–6514. https://doi.org/10.1021/acs.est.7b01272
   PubMed Web of Science ®Google Scholar
• Yadav, S., & Phuleria, H. C. (2020). oxidative potential of particulate matter: A prospective measure to assess PM toxicity. Measurement, analysis and remediation of environmental pollutants. Springer. https://doi.org/10.1007/978-981-15-0540-9_16
   Google Scholar
• Yang, A., Janssen, N. A., Brunekreef, B., Cassee, F. R., Hoek, G., & Gehring, U. (2016). Children's respiratory health and oxidative potential of PM2.5: The PIAMA birth cohort study. Occupational and Environmental Medicine, 73(3), 154–160. https://doi.org/10.1136/oemed-2015-103175
   PubMed Web of Science ®Google Scholar
• Yang, A., Jedynska, A., Hellack, B., Kooter, I., Hoek, G., Brunekreef, B., Kuhlbusch, T. A., Cassee, F. R., & Janssen, N. A. (2014). Measurement of the oxidative potential of PM2. 5 and its constituents: The effect of extraction solvent and filter type. Atmospheric Environment, 83, 35–42. https://doi.org/10.1016/j.atmosenv.2013.10.049
   Web of Science ®Google Scholar
• Yue, Y., Chen, H., Setyan, A., Elser, M., Dietrich, M., Li, J., Zhang, T., Zhang, X., Zheng, Y., Wang, J., & Yao, M. (2018). Size-resolved endotoxin and oxidative potential of ambient particles in Beijing and Zürich. Environmental Science & Technology, 52(12), 6816–6824. https://doi.org/10.1021/acs.est.8b01167
   PubMed Web of Science ®Google Scholar
• Zhang, J., Cheng, H., Wang, D., Zhu, Y., Yang, C., Shen, Y., Yu, J., Li, Y., Xu, S., Zhang, S., Song, X., Zhou, Y., Chen, J., Jiang, J., Fan, L., Wang, C., & Hao, K. (2021). Chronic exposure to pm2.5 nitrate, sulfate, and ammonium causes respiratory system impairments in mice. Environmental Science & Technology, 55(5), 3081–3090. https://doi.org/10.1021/acs.est.0c05814
   PubMed Web of Science ®Google Scholar
• Zhang, X., Staimer, N., Tjoa, T., Gillen, D. L., Schauer, J. J., Shafer, M. M., Hasheminassab, S., Pakbin, P., Longhurst, J., Sioutas, C., & Delfino, R. J. (2016). Associations between microvascular function and short-term exposure to traffic-related air pollution and particulate matter oxidative potential. Environmental Health, 15(1), 1–16. https://doi.org/10.1186/s12940-016-0157-5
   PubMedGoogle Scholar