74
Views
29
CrossRef citations to date
0
Altmetric
Original Article

Differences in activation of G2/M checkpoint in keratinocytes after genotoxic stress induced by hydrogen peroxide and ultraviolet a radiation

, , , &
Pages 405-416 | Received 07 Mar 2000, Published online: 07 Jul 2009

References

  • Griffiths H.R., Mistry P., Herbert K.E., Lunec J. Molecular and cellular effects of ultraviolet light-induced genotoxicity. Critical Reviews in Clinical Laboratory Sciences 1998; 35: 189–237
  • Setlow R.B., Grist E., Thompson K., Woodhead A.D. Wavelengths effective in induction of malignant melanoma. Proceedings of National Academy of Sciences U.S.A. 1993; 90: 6666–6670
  • Setlow R.B. Spectral regions contributing to melanoma: a personal view. Journal of Investigative Dermatology Symposium Proceedings 1999; 4: 46–49
  • Brash D.E., Rudolph J.A., Simon J.A., Lin A., McKenna G.J., Baden H.P., Halperin A.J., Ponten J. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proceedings of National Academy of Sciences U.S.A. 1991; 88: 10124–10128
  • Campbell C., Quinn A.G., Ro Y.S., Angus B., Rees J.L. p53 mutations are common and early events that precede tumor invasion in squamous cell neoplasia of the skin. Journal of Investigative Dermatology 1993; 100: 746–748
  • Nataraj A.J., Trent J.C., Ananthaswamy H.N. p53 gene mutations and photocarcinogenesis. Photochemistry and Photobiology 1995; 62: 218–230
  • McGregor J.M., Crook T., Fraser-Andrews E.A., Rozycka M., Crossland S., Brooks L., Whittaker S.J. Spectrum of p53 gene mutations suggests a possible role for ultraviolet radiation in the pathogenesis of advanced cutaneous lymphomas. Journal of Investigative Dermatology 1999; 112: 317–321
  • Van-der-Zee J., Dubbelman T.M., van-Steveninck J. The role of hydroxyl radicals in the degradation of DNA by ozone. Free Radical Research Communications 1987; 2: 279–284
  • Peak M.J., Peak J.G. Hydroxyl radical quenching agents protect against DNA breakage caused by both 365-nm UVA and by gamma radiation. Photochemistry and Photobiology 1990; 51: 649–652
  • Oroskar A.A., Lambert C., Peak M.J. Effects of hydroxyl radical scavengers on relaxation of super-coiled DNA by aminomethyl-trimethyl-psoralen and monochromatic UVA photons. Free Radical Biology and Medicine 1996; 20: 751–756
  • Kuluncsics Z., Perdiz D., Brulay E., Muel B., Sage E. Wavelength dependence of ultraviolet-induced DNA damage distribution: involvement of direct or indirect mechanisms and possible artefacts. Journal of Photochemistry and Photobiology B 1999; 49: 71–80
  • Robert C., Muel B., Benoit A., Dubertret L., Sarasin A., Stary A. Cell survival and shuttle vector mutagenesis induced by ultraviolet A and ultraviolet B radiation in a human cell line. Journal of Investigative Dermatology 1996; 106: 721–728
  • Deng C., Zhang P., Harper J.W., Elledge S.J., Leder P. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995; 82: 675–684
  • Brugarolas J., Chandrasekaran C., Gordon J.I., Beach D., Jacks T., Hannon G.J. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 1995; 377: 552–557
  • Waldman T., Kinzler K.W., Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Research 1995; 55: 5187–5190
  • Courtois S.J., Woodworth C.D., Degreef H., Garmyn M. Early ultraviolet B-induced G1 arrest and suppression of the malignant phenotype by wild-type p53 in human squamous cell carcinoma cells. Experimental Cell Research 1997; 233: 135–144
  • Petrocelli T., Poon R., Drucker D.J., Slingerland J.M., Rosen C.F. UVB radiation induces p21Cip1/WAF1 and mediates G1 and S phase checkpoints. Oncogene 1996; 12: 1387–1396
  • Smythe C., Newport J.W. Coupling of mitosis to the completion of S phase in xenopus occurs via modulation of the tyrosine kinase that phosphorylates p34cdc2. Cell 1992; 68: 787–797
  • Jessus C., Beach D. Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B. Cell 1992; 68: 323–332
  • Nurse P. Universal control mechanism regulating onset of M-phase. Nature 1990; 344: 503–508
  • Peng C.Y., Graves P.R., Thoma R.S., Wu Z., Shaw A.S., Piwnica-Worms H. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 1997; 277: 1501–1505
  • Nurse P. Checkpoint pathways come of age. Cell 1997; 91: 865–867
  • Sanchez Y., Wong C., Thoma R.S., Richman R., Wu Z., Piwnica-Worms H., Elledge S.J. Conservation of the Chk1 regulation through Cdc25. Science 1997; 277: 1497–1501
  • Millar J.B., Russell P., Dixon J.E., Guan K.L. Negative regulation of mitosis by two functionally overlapping PTPases in fission yeast. EMBO Journal 1992; 11: 4943–4952
  • Heald R., McLoughlin M., McKeon F. Human weel maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase. Cell 1993; 74: 463–474
  • McGowan C.H., Russell P. Cell cycle regulation of human WEE1. EMBO Journal 1995; 14: 2166–2175
  • Furnari B., Blasina A., Boddy M.N., McGowan C.H., Russell P. Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1. Molecular Biology of the Cell 1999; 10: 833–845
  • Bunz F., Dutraux A., Lengauer C., Waldman T., Zhou S., Brown J.P., Sedivy J.M., Kinzler K.W., Vogelstein B. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998; 282: 1497–1501
  • Milligan A., Gabrielli B.G., Clark J.M., Hayward N.K., Ellem K.A. Involvement of p16CDKN2A in cell cycle delays after low dose UV irradiation. Mutation Research 1998; 422: 43–53
  • Boukamp P., Petrussevska R.T., Breitkreutz D., Hornung J., Markham A., Fusenig N.E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. Journal of Cell Biology 1988; 106: 761–771
  • Herzinger T., Funk J.O., Hillmer K., Eick D., Wolf D., Kind A.P. Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase. Oncogene 1995; 11: 2151–2156
  • Bech-Thomsen N., Ravnborg L., Wulf H.C. A quantitative study of the melanogenic effect of multiple suberythemal doses of different ultraviolet radiation sources. Photodermatology Photoimmunology and Photomedicine 1994; 10: 53–56
  • Bech-Thomsen N., Wulf H.C., Poulsen T., Christensen F.G., Lundgren K. Photocarcinogenesis in hairless mice induced by ultraviolet A tanning devices with or without subsequent solar-simulated ultraviolet irradiation. Photodermatology Photoimmunology and Photomedicine 1991; 8: 139–145
  • Kamentsky L.A., Kamentsky L.D. Microscope-based multiparameter laser scanning cytometer yielding data comparable to flow cytometry data. Cytometry 1991; 12: 381–387
  • Clatch R.J., Foreman J.R. Five-color immunophenotyping plus DNA content analysis by laser scanning cytometry. Cytometry 1998; 34: 36–38
  • Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantification of low levels of DNA damage in individual cells. Experimental and Cellular Research 1988; 175: 184–191
  • Anderson D., Yu T.-W., Phillips B.J., Schmezer P. The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the comet assay. Mutation Research 1994; 307: 261–271
  • Lehmann J., Pollet D., Peker S., Steinkraus V., Hoppe U. Kinetics of DNA strand breaks and protection by antioxidants in UVA- or UVB-irradiated HaCaT keratinocytes using single cell gel electrophoresis assay. Mutation Research 1998; 407: 97–108
  • Petersen A.B., Gniadecki R., Wulf H.C. Laser scanning cytometry for comet assay analysis. Cytometry 2000; 39: 10–15
  • Chen Q., Ames B.N. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proceedings of National Academy of Sciences U.S.A. 1994; 91: 4130–4134
  • Flattery-O'Brien J.A., Dawes I.W. Hydrogen peroxide causes RAD9-dependent cell cycle arrest in G2 in Saccharomyces cerevisiae whereas menadione causes G1 arrest independent of RAD9 function. Journal of Biological Chemistry 1998; 273: 8564–8571
  • Wharton W. Cell cycle constraints on peroxide- and radiation-induced inhibitory checkpoints. Cancer Research 1995; 55: 5069–5074
  • Clopton D.A., Saltman P. Low-level oxidative stress causes cell-cycle specific arrest in cultured cells. Biochemical and Biophysical Research Communication 1995; 210: 189–196
  • Halliwell B., Aruoma O.I. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS Letters 1991; 281: 9–19
  • Hoffmann M.E., Mello-Filho A.C., Meneghini R. Correlation between cytotoxic effect of hydrogen peroxide and the yield of DNA strand breaks in cells of different species. Biochimica et Biophysica Acta 1984; 781: 234–238
  • Morrison H., Jernstrom B., Nordenskjold M., Thor H., Orrenius S. Induction of DNA damage by menadione (2-methyl-1,4-naphthoquinone) in primary cultures of rat hepatocytes. Biochemical Pharmacology 1984; 33: 1763–1769
  • Friedberg E.C., Walker G.C., Siede W. DNA Repair and Mutagenesis. ASM Press, Washington, DC 1995
  • Gniadecki R., Thorn T., Vicanova J., Petersen A., Wulf H.C. Role of mitochondria in ultraviolet-induced oxidative stress. Journal of Cellular Biochemistry 2000, In press
  • Petersen A.B., Gniadecki R., Vicanova J., Thorn T., Wulf H.C. Hydrogen peroxide is responsible for UVA-induced DNA damage measured by alkaline comet assay in HaCaT keratinocytes. Hydrogen peroxide is responsible for UVA-induced DNA damage measured by alkaline comet assay in HaCaT keratinocytes. Journal of Photochemistry and Photobiology B: Biology 2001, in press
  • Eller M.S., Maeda T., Magnoni C., Atwal D., Gilchrest B.A. Enhancement of DNA repair in human skin cells by thymidine dinucleotides: evidence for a p53-mediated mammalian SOS response. Proceedings of National Academy of Sciences U.S.A. 1997; 94: 12627–12632
  • de Laat A., van Tilburg M., van der Leun J.C., van Vloten W.A., de Gruijl F.R. Cell cycle kinetics following UVA irradiation in comparison to UVB and UVA irradiation. Photochemistry and Photobiology 1996; 63: 492–497
  • Arlett C.F., Lowe J.E., Harcourt S.A., Waugh A.P., Cole J., Roza L., Diffey B.L., Mori T., Nikaido O., Green M.H. Hypersensitivity of human lymphocytes to UV-B and solar irradiation. Cancer Research 1993; 53: 609–614

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.