Oxidative Stress-related Alteration of the Copy Number of Mitochondrial DNA in Human Leukocytes

References

• Lee, H.C. and Wei, Y.H. (2002) "Mitochondrial alterations, cellular responses to oxidative stress and defective protein degradation in aging", Biogerontology 2, 231–244.
   Google Scholar
• Maller-Höcker, J., Schafer, S. and Li, K. (2001) "Immunocyto-chemical localization of mitochondrial single-stranded DNA-binding protein in mitochondria-rich cells of normal and neoplastic human tissue", Appl. Immunohistochem. 9,276–280.
   PubMedGoogle Scholar
• Miiller-Hocker, J., Muntau, A., Schafer, S., Jaksch, M., Staudt, F., Pongratz, D. and Taanman, J.W. (2002) "Depletion of mitochondrial DNA in the liver of an infant with neonatal giant cell hepatitis", Hum. Pathol. 33, 247–253.
   PubMedGoogle Scholar
• Lee, H.C., Lu, C.Y., Fahn, H.J. and Wei, Y.H. (1998) "Aging-and smoking-associated alteration in the relative content of mitochondrial DNA in human lung", FEBS Lett. 441,292–296.
   PubMed Web of Science ®Google Scholar
• Lee, H.C., Yin, P.H., Lu, C.Y., CM, C.W. and Wei, Y.H. (2000) "Increase of mitochondria and mitochondrial DNA in response to oxidative stress in cultured human cells", Biochem. J. 348, 425–432.
   PubMed Web of Science ®Google Scholar
• Wei, Y.H., Lee, C.F., Lee, H.C., Ma, Y.S., Wang, C.W., Lu, C.Y. and Pang, C.Y. (2001) "Increases of mitochondrial mass and mitochondrial genome in association with enhanced oxi-dative stress in human cells harboring 4,977 bp-deleted mitochondrial DNA", Ann. N.Y. Acad. Sci. 928, 97–112.
   PubMed Web of Science ®Google Scholar
• Suomalainen, A. and Kaukonen, J. (2001) "Diseases caused by nuclear genes affecting mtDNA stability", Am. J. Med. Genet. 106, 53–61.
   PubMed Web of Science ®Google Scholar
• Tsai, K., Hsu, T.G., Lu, F.J., Hsu, C.F., Liu, T.Y. and Kong, C.W. (2001) "Age-related changes in the mitochondrial depolari-zation induced by oxidative injury in human peripheral blood leukocytes", Free Radic. Res. 35, 395–403.
   PubMed Web of Science ®Google Scholar
• Ames, B.N. (1998) "Micronutrients prevent cancer and delay aging", Toxicol. Lett. 102–103, 5–18.
   Google Scholar
• Penckofer, S., Schwertz, D. and Florczak, K. (2002) "Oxidative stress and cardiovascular disease in type 2 diabetes: the role of antioxidants and pro-oxidants", J. Cardiovasc. Nurs. 16, 68–85.
   PubMedGoogle Scholar
• Lee, K.U. (2001) "Oxidative stress markers in Korean subjects with insulin resistance syndrome", Diabet. Res. Clin. Pract. 54, S29—S33.
   Google Scholar
• Liu, CS., Chen, H.W., Lii, C.K., Chen, S.C. and Wei, Y.H. (1998) "Alterations of small-molecular-weight antioxidants in the blood of smokers", Chem.-Biol. Interact. 116, 143–154.
   PubMed Web of Science ®Google Scholar
• Pang, C.Y., Huang, C.C., Yen, M.Y., Wang, E.K., Kao, K.P., Chen, S.S. and Wei, Y.H. (1999) "Molecular epidemiologic study of mitochondrial DNA mutations in patients with mitochondrial diseases in Taiwan", J. Formos. Med. Assoc. 98, 326–334.
   PubMedGoogle Scholar
• Kendall, T.L., Byerley, D.J. and Dean, R. (1991) "Isolation of DNA from blood", Anal. Biochem. 195, 74–76.
   PubMed Web of Science ®Google Scholar
• Wong, A. and Cortopassi, G. (2002) "Reproducible quantita-tive PCR of mitochondrial and nuclear DNA copy number using the LightCycler", Methods Mol. Biol. 197, 129–137.
   PubMedGoogle Scholar
• Liu, CS., Kao, S.H. and Wei, Y.H. (1997) "Smoking-associated mitochondrial DNA mutations in the human hair follicle", Environ. Mol. Mutagen. 30, 47–55.
   PubMed Web of Science ®Google Scholar
• Shigenaga, M.K., Aboujaoude, E.N., Chen, Q. and Ames, B.N. (1994) "Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection", Methods Enzymol. 234, 16–33.
   PubMed Web of Science ®Google Scholar
• Dudman, N.P.B., Guo, X.W., Crooks, R., Xie, L. and Silberberg, J.S. (1996) "Assay of plasma homocysteine: light sensitivity of the fluorescent 7-benzo-2-oxa-1,3-diazole-4-sulfonic acid derivative, and use of appropriate calibrators", Clin. Chem. 42, 2028–2032.
   PubMed Web of Science ®Google Scholar
• Dousseet, J.C., Trouilh, M. and Foglientti, M.J. (1983) "Plasma malondialdehyde levels during myocardial infarction", Clin. Chim. Acta 129, 319–322.
   PubMedGoogle Scholar
• Boyne, A.F. and Ellman, G.L. (1972) "A methodology for analysis of tissue sulfhydryls components", Anal. Biochem. 46, 639–653.
   PubMed Web of Science ®Google Scholar
• Reed, D.J., Babson, J.R., Beatty, P.W., Brodie, A.E., Ellis, W.W. and Potter, D.W. (1980) "High-performance liquid chromato-graphy analysis of nanomole levels of glutathione, gluta-thione disulfide, and related thiols and disulfides", Anal. Biochem. 106, 55–62.
   PubMed Web of Science ®Google Scholar
• Lowry, OB., Rosebrough, N.J., Farr, A.L. and Randall, R.J. (1951) "Protein measurement with folin phenol reagent", J. Biol. Chem. 193, 265–275.
   PubMed Web of Science ®Google Scholar
• Catignani, GI. and Bieri, J.G. (1983) "Simultaneous determi-nation of retinol and a-tocopherol in serum or plasma by liquid chromatography", Clin. Chem. 29, 708–712.
   PubMed Web of Science ®Google Scholar
• Kyaw, A. (1978) "A simple colorimetric method for ascorbate determination in blood plasma", Clin. Chim. Acta 86, 153–157.
   PubMed Web of Science ®Google Scholar
• Pieri, C., Recchioni, R. and Moroni, F. (1993) "Age-dependent modifications of mitochondrial trans-membrane potential and mass in rat splenic lymphocytes during proliferation", Mech. Ageing Dev. 70, 201–212.
   PubMed Web of Science ®Google Scholar
• Choi, Y.S., Kim, S. and Pak, Y.K. (2001) "Mitochondrial transcription factor A (mtTFA) and diabetes", Diabet. Res. Clin. Pract. 12, S3—S9.
   Google Scholar
• Chen, D., Cao, G., Hastings, T., Feng, Y., Pei, W., O'Horo, C. and Chen, J. (2002) "Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria", J. Neurochem. 81, 1273–1284.
   PubMed Web of Science ®Google Scholar
• Hayakawa, M., Toni, K., Sugiyama, S., Tanaka, M. and Ozawa, T. (1991) "Age-associated accumulation of 8-hydroxydeoxyguanosine in mitochondrial DNA of human diaphragm", Biochem. Biophys. Res. Commun. 179, 1023–1029.
   PubMed Web of Science ®Google Scholar
• Bhatt, K., Shah, B., Needler, N., Delehanty, J.M. and Thornton, C.A. (2003) "Reduced amount of mitochondrial DNA in aged human muscle", J. Appl. Physiol. 94, 1479–1484.
   PubMedGoogle Scholar
• Pollack, M. and Leeuwenburgh, C. (2001) "Apoptosis and aging: role of the mitochondria", J. Gerontol. Part A. Biol. 56, B475—B482.
   Google Scholar
• Drouet, M., Lauthier, F., Charmes, J.P., Sauvage, P. and Ratinaud, M.H. (1999) "Age-associated changes in mitochon-drial parameters on peripheral human lymphocytes", Exp. Gerontol. 34, 843–852.
   PubMedGoogle Scholar
• Perna, A.F., Ingrosso, D., Lombardi, C., Acanfora, F., Satta, E., Cesare, C.M., Violetti, E., Romano, M.M. and De-Santo, N.G. (2003) "Possible mechanisms of homocysteine toxicity", Kidney Int. Suppl. 84, 137–140.
   Google Scholar
• McCully, KS. (1994) "Chemical pathology of homocysteine DI Cellular function and aging", Ann. Clin. Lab. Sci. 24, 134–152.
   PubMedGoogle Scholar
• Walter, P.B., Knutson, M.D., Paler-Martinez, A., Lee, S., Xu, Y, Viteri, F.E. and Ames, B.N. (2002) "Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats", Proc. Natl Acad. Sci. USA 99, 2264–2269.
   Google Scholar
• Tan, G., Chen, L.S., Lonnerdal, B., Genera, C., Taroni, F.A. and Cortopassi, G.A. (2001) "Frataxin expression rescues mito-chondrial dysfunctions in FRDA cells", Hum. Mol. Genet. 10, 2099–2107.
   PubMed Web of Science ®Google Scholar
• Gutteridge, J.M., Halliwell, B., Treffry, A., Harrison, P.M. and Blake, D. (1983) "Effect of ferritin-containing fractions with different iron loading on lipid permddation", Biochem. J. 209, 557–560.
   PubMed Web of Science ®Google Scholar
• Soriani, M., Pietraforte, D. and Minetti, M. (1994) "Antioxi-dant potential of anaerobic human plasma: role of serum albumin and thiols as scavengers of carbon radicals", Arch. Biochem. Biophys. 312, 180–188.
   PubMed Web of Science ®Google Scholar
• Thomas, S.M., Gebicki, J.M. and Dean, R.T. (1989) "Radicals initiated a-tocopherol depletion and lipid peroxidation in mitochondrial membranes", Biochim. Biophys. Acta 1002, 189–197.
   PubMed Web of Science ®Google Scholar
• Lass, A., Forster, M.J. and Sohal, R.S. (1999) "Effects of coenzyme Qio and alpha-tocopherol administration on their tissue levels in the mouse: elevation of mitochondrial a-tocopherol by coenzyme Qv", Free Radic. Biol. Med. 26, 1375–1382.
   PubMed Web of Science ®Google Scholar
• Lewis, W., Copeland, W.C. and Day, B.J. (2001) "Mitochon-drial DNA depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse trans-criptase inhibitors", Lab. Investig. 81, 777–790.
   PubMed Web of Science ®Google Scholar
• Giulivi, C. and Cadenas, E. (1998) "The role of mitochondrial glutathione in DNA base oxidation", Biochim. Biophys. Acta 7, 265–274.
   Google Scholar
• Liu, C.S. and Wei, Y.H. (1999) "Age-associated alteration of blood thiol-group-related antioxidants in smokers", Environ. Res. 80, 18–24.
   PubMedGoogle Scholar
• Fernandez-Checa, J.C., Kaplowitz, N., Garcia-Ruiz, C., Colell, A., Miranda, M., Mari, M., Ardite, E. and Morales, A. (1997) "GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect", Am. J. Physiol. 273, 7–17.
   PubMed Web of Science ®Google Scholar
• Accordi, F. and Chimenti, C. (2003) "Retinol-induced apoptosis in larval pancreas of Bufo bufo", J. Anat. 202, 309–314.
   PubMedGoogle Scholar
• Villarroya, F., Giralt, M. and Iglesias, R. (1999) "Retinoids and adipose tissues: metabolism, cell differentiation and gene expression", Int. J. Obes. Relat. Metab. Disord. 23, 1–6.
   PubMed Web of Science ®Google Scholar
• Everts, H.B., Claassen, DO., Hermoyian, C.L. and Berdanier, C.D. (2002) "Nutrient-gene interactions: dietary vitamin A and mitochondrial gene expression", Life Sci. 53, 295–301.
   Google Scholar
• Bashir, S., Harris, G., Denman, M.A., Blake, D.R. and Winyard, P.G. (1993) "Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases", Ann. Rheum. Dis. 52, 659–666.
   PubMed Web of Science ®Google Scholar
• Inoue, T., Mu, Z., Sumikawa, K., Adachi, K. and Okochi, T. (1993) "Effect of physical exercise on the content of 8-hydroxydeoxyguanosine in nuclear DNA prepared from human lymphocytes", Jpn. J. Cancer Res. 84, 720–725.
   PubMedGoogle Scholar
• Kiyosawa, H., Suko, M., Okudaira, H., Murata, K., Miyamoto, T., Chung, M.H., Kasai, H. and Nishimura, S. (1990) "Cigarette smoking induces formation of 8-hydroxydeoxy-guanosine, one of the oxidative DNA damages in human peripheral leukocytes", Free Radic. Res. Commun. 11, 23–27.
   PubMed Web of Science ®Google Scholar
• Asami, S., Hirano, T., Yamaguchi, R., Tomioka, Y., Itoh, H. and Kasai, H. (1996) "Increase of a type of oxidative DNA damage, 8-hydroxyguanine, and its repair activity in human leukocytes by cigarette smoking", Cancer Res. 56, 2546–2549.
   PubMed Web of Science ®Google Scholar
• Lezza, A.M., Mecocci, P., Cormio, A., Beal, ME, Cherubini, A., Cantatore, P., Senin, U. and Gadaleta, M.N. (1999) "Mitochondrial DNA 4977bp deletion and 80HdG levels correlate in the brain of aged subjects but not Alzheimer's disease patients", FASEB J. 13, 1083–1088.
   PubMedGoogle Scholar
• Camplejohn, R.S., Gilchrist, R., Easton, D., McKenzie-Edwards, E., Barnes, D.M., Eccles, D.M., Ardern-Jones, A., Hodgson, S.V., Duddy, P.M. and Eeles, R.A. (2003) "Apopto-sis, ageing and cancer susceptibility", Br. J. Cancer 88, 487–490.
   PubMedGoogle Scholar