Pro-oxidant Role of Heme Oxygenase in Mediating Glucose-induced Endothelial Cell Damage

References

• Giugliano, D., Ceriello, A. and Paolisso, G. (1995) "Diabetes mellitus, hypertension, and cardiovascular disease: which role for oxidative stress?", Metabolism 44, 363–368.
   PubMed Web of Science ®Google Scholar
• Mohamed, AK., Bierhaus, A., Schiekofer, S., Tritschler, H., Ziegler, R. and Nawroth, P.P. (1999) "The role of oxidative stress and NF-kappaB activation in late diabetic complica-tions", Biofactors 10, 157–167.
   PubMed Web of Science ®Google Scholar
• Pessin, J.E. and Bell, G.I. (1992) "Mammalian facilitative glucose transporter family: structure and molecular regula-tion", Annu. Rev. Physiol. 54, 911–930.
   PubMed Web of Science ®Google Scholar
• Brownlee, M. (2001) "Biochemistry and molecular cell biology of diabetic complications", Nature 414, 813–820.
   PubMed Web of Science ®Google Scholar
• Chakrabarti, S., Khan, Z.A., Cukiernik, M., Fukuda, G., Chen, S. and Mukherjee, S. (2002) "Alteration of endo-thelins: a common pathogenetic mechanism in chronic diabetic complications", Int. J. Exp. Diabetes Res. 3, 217–231.
   PubMedGoogle Scholar
• Khan, Z.A. and Chakrabarti, S. (2003) "Endothelins in chronic diabetic complications", Can. J. Physiol. Pharmacol. 81,622–634.
   PubMed Web of Science ®Google Scholar
• Cukiernik, M., Mukherjee, S., Downey, D. and Chakrabarti, S. (2003) "Heme oxygenase in the retina in diabetes", Curr. Eye Res. 27, 301–308.
   PubMed Web of Science ®Google Scholar
• Farhangkhoee, H., Khan, Z.A., Mukherjee, S., Cukiernik, M., Barbin, Y.P., Karmazyn, M. and Chakrabarti, S. (2003) "Heme oxygenase in diabetes-induced oxidative stress in the heart", J. Mol. Cell Cardiol. 35, 1439–1448.
   PubMed Web of Science ®Google Scholar
• Maines, M.D. (1988) "Heme oxygenase: function, multiplicity, regulatory mechanisms, and clinical applications", FASEB J. 2, 2557–2568.
   PubMed Web of Science ®Google Scholar
• McCoubrey, W.K., Huang, T.J. and Maines, M.D. (1997) "Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3", Eur. J. Biochem. 247, 725–732.
   PubMedGoogle Scholar
• Buelow, R., Tullius, S.G. and Volk, H.D. (2001) "Protection of grafts by hemoxygenase-1 and its toxic product carbon monoxide", Am. J. Transplant. 1, 313–315.
   PubMed Web of Science ®Google Scholar
• Otterbein, L.E. and Choi, A.M. (2000) "Heme oxygenase: colors of defense against cellular stress", Am. J. Physiol. Lung Cell Mol. Physiol. 279, L1029—L1037.
   PubMed Web of Science ®Google Scholar
• Clark, I.E., Foresti, R., Sarathchandra, R, Kaur, H., Green, C.J. and Motterlini, R. (2000) "Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction", Am. J. Physiol. Heart Circ. Physiol. 278, H643—H651.
   Web of Science ®Google Scholar
• Fujita, T., Toda, K., Karimova, A., Yan, S.F., Naka, Y, Yet, S.F. and Pinsky, D.J. (2001) "Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepres-sion of fibrinolysis", Nat. Med. 7, 598–604.
   PubMed Web of Science ®Google Scholar
• Dennery, P.A., Spitz, D.R., Yang, G., Tatarov, A., Lee, CS., Shegog, M.L. and Poss, K.D. (1998) "Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2", J. Clin. Investig. 101, 1001–1011.
   PubMed Web of Science ®Google Scholar
• Foresti, R. and Motterlini, R. (1999) "The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis", Free Radic. Res. 31, 459–475.
   PubMed Web of Science ®Google Scholar
• Takahashi, K., Hara, E., Suzuki, H., Sasano, H. and Shibahara, S. (1996) "Expression of heme oxygenase isozyme mRNAs in the humanbrain and induction of heme oxygenase-1 by nitric oxide donors", J. Neurochem. 67,482–489.
   PubMed Web of Science ®Google Scholar
• Dulak, J., Jozkowicz, A., Foresti, R., Kasza, A., Frick, M., Huk, I., Green, C.J., Pachinger, 0., Weidinger, F. and Motterlini, R. (2002) "Heine oxygenase activity modulates vascular endo-thelial growth factor synthesis in vascular smooth muscle cells", Antioxid. Redox Signal. 4, 229–240.
   PubMed Web of Science ®Google Scholar
• Chen, S., Apostolova, M.D., Cherian, M.G. and Chakrabarti, S. (2000) "Interaction of endothelin-1 with vasoactive factors in mediating glucose-induced increased permeability in endo-thelial cells", Lab. Investig. 80, 1311–1321.
   PubMed Web of Science ®Google Scholar
• Chen, S., Mukherjee, S., Chakraborty, C. and Chakrabarti, S. (2002) "High glucose-induced, endothelin-dependent fibro-nectin synthesis is mediated via NF-kappa B and AP-1", Am. J. Physiol. Cell Physiol. 284, C263—C272.
   Web of Science ®Google Scholar
• Evans, T., Deng, D.X., Chen, S. and Chakrabarti, S. (2000) "Endothelin receptor blockade prevents augmented extra-cellular matrix component mRNA expression and capillary basement membrane thickening in the retina of diabetic and galactose-fed rats", Diabetes 49, 662–666.
   PubMed Web of Science ®Google Scholar
• Khan, Z.A., Cukiernik, M., Gonder, J.R. and Chakrabarti, S. (2004) "Oncofetal fibronectin in diabetic retinopathy", Investig. Ophthalmol. Vis. Sci. 45, 287–295.
   PubMed Web of Science ®Google Scholar
• Chen, S., Khan, Z.A., Cukiernik, M. and Chakrabarti, S. (2003) "Differential activation of NF-kappa B and AP-1 in increased fibronectin synthesis in target organs of diabetic complications", Am. J. Physiol. Endocrinol. Metab. 284, E1089—E1097.
   Web of Science ®Google Scholar
• McLean, M., Bowman, M., Clifton, V, Smith, R. and Grossman, A.B. (2000) "Expression of the heme oxygenase-carbon monoxide signalling system in human placenta", J. Clin. Endocrinol. Metab. 85, 2345–2349.
   PubMed Web of Science ®Google Scholar
• Ryter, S.W., Kvam, E. and Tyrrell, R.M. (2000) "Heme oxygenase activity. Current methods and applications", Methods Mol. Biol. 99, 369–391.
   PubMedGoogle Scholar
• Yarborough, A., Zhang, Y.J., Hsu, T.M. and Santella, R.M. (1996) "Immunoperoxidase detection of 8-hydroxydeoxy-guanosine in aflatoxin B1-treated rat liver and human oral mucosal cells", Cancer Res. 56, 683–688.
   PubMed Web of Science ®Google Scholar
• Sardana, M.K. and Kappas, A. (1987) "Dual control mechanism for heme oxygenase: tin(IV)-protoporphyrin potently inhibits enzyme activity while markedly increasing content of enzyme protein in liver", Proc. Natl Acad. Sci. USA 84, 2464–2468.
   PubMed Web of Science ®Google Scholar
• Cosso, L., Maineri, E.P., Traverso, N., Rosatto, N., Pronzato, M.A., Cottalasso, D., Marinari, U.M. and Odetti, P. (2001) "Induction of heme oxygenase 1 in liver of spontaneously diabetic rats", Free Radic. Res. 34, 189–191.
   PubMed Web of Science ®Google Scholar
• Hayashi, K., Haneda, M., Koya, D., Maeda, S., Isshiki, K. and Kikkawa, R. (2001) "Enhancement of glomerular heme oxygenase-1 expression in diabetic rats", Diabetes Res. Clin. Pract. 52, 85–96.
   PubMed Web of Science ®Google Scholar
• Hammes, H.P., Bartmann, A., Engel, L. and Wulfroth, P. (1997) "Antioxidant treatment of experimental diabetic retinopathy in rats with nicanartine", Diabetologia 40, 629–634.
   PubMed Web of Science ®Google Scholar
• Stocker, R., Yamamoto, Y, McDonagh, A.F., Glazer, A.N. and Ames, B.N. (1987) "Bilirubin is an antioxidant of possible physiological importance", Science 235, 1043–1046.
   PubMed Web of Science ®Google Scholar
• Stocker, R. and Ames, B.N. (1987) "Potential role of conjugated bilirubin and copper in the metabolism of lipid peroxides in bile", Proc. Natl Acad. Sci. USA 84, 8130–8134.
   PubMed Web of Science ®Google Scholar
• Balla, G., Jacob, H.S., Balla, J., Rosenberg, M., Nath, K., Apple, F., Eaton, J.W. and Vercellotti, G.M. (1992) "Ferritin: a cytoprotective antioxidant strategem of endothelium", J. Biol. Chem. 267, 18148–18153.
   PubMed Web of Science ®Google Scholar
• Noguchi, M., Yoshida, T. and Kikuchi, GA. (1983) "Stoichio-metric study of heme degradation catalyzed by reconstituted heme oxygenase system with special consideration of the production of hydrogen peroxide during the reaction", J. Biochem. 93, 1027–1036.
   PubMed Web of Science ®Google Scholar
• Cadenas, E. (1989) "Biochemistry of oxygen toxicity", Ann. Rev. Biochem. 58, 79–110.
   PubMed Web of Science ®Google Scholar
• Aust, S.D., Morehouse, S.A. and Tomas, C.E. (1985) "Role of metals in oxygen radical reactions", Free Radic. Biol. Med. 1, 3–25.
   Google Scholar
• Bussolati, B., Ahmed, A., Pemberton, H., Landis, R.C., Di Carlo, F., Haskard, D.O. and Mason, J.C. (2003) "Bifunctional role for VEGF-induced heme oxygenase-1 in vivo: induction of angiogenesis and inhibition of leukocytic infiltration", Blood 103, 761–766.
   PubMed Web of Science ®Google Scholar
• Jozkowicz, A., Huk, I., Nigisch, A., Weigel, G., Dietrich, W., Motterlini, R. and Dulak, J. (2003) "Heme oxygenase and angiogenic activity of endothelial cells: stimulation by carbon monoxide and inhibition by tin protoporphyrin-IX", Antioxid. Redox Signal 5, 155–162.
   PubMed Web of Science ®Google Scholar
• Zhang, F., Kaide, J.I., Yang, L., Jiang, H., Quan, S., Kemp, R., Gong, W., Balazy, M., Abraham, N.G. and Nasjletti, A. (2003) "CO modulates pulmonary vascular response to acute hypoxia: relation to endothelin", Am. J. Physiol. Heart Circ. Physiol. 286, H137—H144.
   Web of Science ®Google Scholar
• Nishio, Y., Kashiwagi, A., Taki, H., Shinozaki, K., Maeno, Y., Kojima, H., Maegawa, H., Haneda, M., Hidaka, H., Yasuda, H., Horrike, K. and Kikkawa, R. (1998) "Altered activities of transcription factors and their related gene expression in cardiac tissues of diabetic rats", Diabetes 47, 1318–1325.
   PubMed Web of Science ®Google Scholar