83
Views
8
CrossRef citations to date
0
Altmetric
Original Article

Nitrite Generates an Oxidant Stress and Increases Nitric Oxide in EA.hy926 Endothelial Cells

, &
Pages 581-589 | Received 16 Feb 2004, Published online: 07 Jul 2009

References

  • Lloyd-Jones, D.M. and Bloch, K.D. (1996) "The vascular biology of nitric oxide and its role in atherogenesis", Annu. Rev. Med. 47, 365–375.
  • Weyer, R., Stroes, E. and Rabelink, T.J. (1998) "Nitric oxide and hypercholesterolemia: a matter of oxidation and reduction?", Atherosclerosis 137, S51–S60.
  • Napoli, C. and Ignarro, L.J. (2001) "Nitric oxide and atherosclerosis", Nitric Oxide 5, 88–97.
  • Lancaster, J.R. Jr. (1994) "Simulation of the diffusion and reaction of endogenously produced nitric oxide", Proc. Natl Acad. Sci. USA 91, 8137–8141.
  • Ignarro, L.J., Fukuto, J.M., Griscavage, J.M., Rogers, N.M. and Byrns, R.E. (1993) "Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine", Proc. Natl Acad. Sci. USA 90, 8103–8107.
  • Reszka, K.J., Matuszak, Z., Chignell, C.F. and Dillon, J. (1999) "Oxidation of biological electron donors and antioxidants by a reactive lactoperoxidase metabolite from nitrite (NO2-), an EPR and spin trapping study", Free Radic. Biol. Med. 26, 669–678.
  • Green, L.C., Wagner, D.A., Glogowski, J., Skipper, Pi., Wishnok, J.S. and Tannenbaum, S.R. (1982) "Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids", Anal. Biochem. 126, 131–138.
  • Leone, A.M., Francis, Pi., Rhodes, P. and Moncada, S. (1994) "A rapid and simple method for the measurement of nitrite and nitrate in plasma by high performance capillary electrophoresis", Biochem. Biophys. Res. Commun. 200, 951–957.
  • Doyle, M.P., Herman, J.G. and Dykstra, R.L. (1985) "Auto-catalytic oxidation of hemoglobin induced by nitrite: activation and chemical inhibition", J. Free Radic. Biol. Med. 1, 145–153.
  • Chance, B. (1950) "On the reaction of catalase peroxides with acceptors", J. Biol. Chem. 182, 649–659.
  • Cohen, G., Martinez, M. and Hochstein, P. (1964) "Generation of hydrogen peroxide during reaction of nitrite with oxyhemoglobin", Biochemistry 3, 901–903.
  • Zhang, Z., Naughton, D., Winyard, PG., Benjamin, N., Blake, D.R. and Symons, M.C. (1998) "Generation of nitric oxide by a nitrite reductase activity of xanthine oxidase: a potential pathway for nitric oxide formation in the absence of nitric oxide synthase activity", Biochem. Biophys. Res. Commun. 249, 767–772.
  • Millar, T.M., Stevens, C.R., Benjamin, N., Eisenthal, R., Harrison, R. and Blake, D.R. (1998) "Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions", FEBS Lett. 427, 225–228.
  • Godber, B.L., Doel, J.J., Sapkota, G.P., Blake, DR., Stevens, C.R., Eisenthal, R. and Harrison, R. (2000) "Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase", J. Biol. Chem. 275, 7757–7763.
  • Magos, L., Sziza, M. and Szirtes, M. (1958) "Die Wirkung von Ascorbinsdure out durch Nitrit verursachte Methämoglobin-dmie", Naturwissenschaften 16, 385–386.
  • Zweier, J.L., Samouilov, A. and Kuppusamy, P. (1999) "Non-enzymatic nitric oxide synthesis in biological systems", Biochim. Biophys. Acta 1411, 250–262.
  • Mirvish, S.S., Wallcave, L., Eagen, M. and Shubik, P. (1972) "Ascorbate-nitrite reaction: possible means of blocking the formation of carcinogenic N-nitroso compounds", Science 177, 65–68.
  • Gruetter, C.A., Kadowitz, P.J. and Ignarro, L.J. (1981) "Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite", Can. J. Physiol. Pharmacol. 59, 150–156.
  • May, J.M., Qu, Z.C., Xia, L. and Cobb, C.E. (2000) "Nitrite uptake and metabolism and oxidant stress in human erythrocytes", Am. J. Physiol. Cell Physiol. 279, C1946–C1954.
  • Edgell, C.J., McDonald, C.C. and Graham, J.B. (1983) "Permanent cell line expressing human factor VBI-related antigen established by hybridization", Proc. Natl Acad. Sci. USA 80, 3734–3737.
  • Lindberg, R.A., Dewhirst, MW., Buckley, B.J., Hughes, C.S. and Whorton, A.R. (1996) "Ca2±-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells", Am. J. Physiol. 271, C332–C337.
  • Pech-Amsellem, MA., Myara, I., Pico, I., Maziere, C., Maziere, J.C. and Moatti, N. (1996) "Oxidative modifications of low-density lipoproteins (LDL) by the human endothelial cell line EA.hy 926", Experientia 52, 234–238.
  • May, J.M., Qu, Z.-C. and Mendiratta, S. (1998) "Protection and recycling of ek-tocopherol in human erythrocytes by intra-cellular ascorbic acid", Arch. Biochem. Biophys. 349, 281–289.
  • Hissin, P.J. and Hill, R. (1976) "A fluorometric method for determination of oxidized and reduced glutathione in tissues", Anal. Biochem. 74, 214–226.
  • Saville, B. (1958) "A scheme for the colorimetric determi-nation of microgram amounts of thiols", J. Am. Chem. Soc. 83, 670–672.
  • Cortas, N.K. and Wakid, N.W. (1990) "Determination of inorganic nitrate in serum and urine by a kinetic cadmium-reduction method", Clin. Chem. 36, 1440–1443.
  • Jones, W., Li, X., Perriott, L.M., Whitesell, R.R. and May, J.M. (2002) "Uptake, recycling, and antioxidant functions of a-lipoic acid in endothelial cells", Free Radic. Biol. Med. 33, 83–93.
  • Padgett, C.M. and Whorton, A.R. (1995) "S-nitroso-glutathione reversibly inhibits GAPDH by S-nitrosylation", Am. J. Physiol. Cell Physiol. 269, C739—C749.
  • Schuler, R.H. (1977) "Oxidation of ascorbate anion by electron transfer to phenoxyl radicals", Radiat. Res. 69, 417–433.
  • Bradford, M.M. (1976) "A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein—dye binding", Anal. Biochem. 72, 248–254.
  • Kojima, H., Sakurai, K., Kikuchi, K., Kawahara, S., Kirino, Y, Nagoshi, H., Hirata, Y. and Nagano, T. (1998) "Development of a fluorescent indicator for nitric oxide based on the fluorescein chromophore", Chem. Pharm. Bull. (Tokyo) 46, 373–375.
  • Padgett, C.M. and VVhorton, A.R. (1997) "Glutathione redox cycle regulates nitric oxide-mediated glyceraldehyde-3-phosphate dehydrogenase inhibition", Am. J. Physiol. Cell Physiol. 272, C99 —C108.
  • Shingles, R., Roh, M.H. and McCarty, RT. (1997) "Direct measurement of nitrite transport across erythrocyte mem-brane vesicles using the fluorescent probe, 6-methoxy-N-(3-sulfopropyl) quinolinium", J. Bioenerg. Biomembr. 29, 611–616.
  • Baird, J.K. (1984) "Methylene blue-mediated hexose mono-phosphate shunt stimulation in human red blood cells in vitro: independence from intracellular oxidative injury", Int. J. Biochem. 16, 1053–1058.
  • Tampo, Y, Kotamraju, S., Chitambar, CR., Kalivendi, S.V., Keszler, A., Joseph, J. and Kalyanaraman, B. (2003) "Oxidative stress-induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial cells: role of transferrin receptor-dependent iron uptake in apoptosis", Circ. Res. 92, 56–63.
  • May, J.M., Qu, Z.-C. and Li, X. (2003) "Ascorbic acid blunts oxidant stress due to menadione in endothelial cells", Arch. Biochem. Biophys. 411, 136–144.
  • Burner, U., Furtmaller, P.C., Kettle, A.J., Koppenol, W.H. and Obinger, C. (2000) "Mechanism of reaction of myeloper-oxidase with nitrite", J. Biol. Chem. 275, 20597–20601.
  • Kociba, R.J. and Sleight, S.D. (1970) "Nitrite toxicosis in the ascorbic acid-deficient guinea pig", Toxicol. Appl. Pharmacol. 16, 424–429.
  • Gladwin, M.T., Shelhamer, J.H., Schechter, AN., Pease-Fye, MT., Waclawiw, MA., Panza, J.A., Ognibene, EP. and Cannon, R.O. ifi (2000) "Role of circulating nitrite and S-nitrosohemoglobin in the regulation of regional blood flow in humans", Proc. Natl Acad. Sci. USA 97, 11482–11487.
  • Gladwin, M.T. (2004) "Haldane, hot dogs, halitosis, and hypoxic vasodilation: the emerging biology of the nitrite anion", J. Clin. Investig. 113, 19–21.
  • Kojima, H., Nakatsubo, N., Kikuchi, K., Kawahara, S., Kirin°, Y., Nagoshi, H., Hirata, Y. and Nagano, T. (1998) "Detection and imaging of nitric oxide with novel fluorescent indicators: diaminofluoresceins", Anal. Chem. 70, 2446–2453.
  • Nakatsubo, N., Kojima, H., Kikuchi, K., Nagoshi, H., Hirata, Y., Maeda, D., Imai, Y., Irimura, T. and Nagano, T. (1998) "Direct evidence of nitric oxide production from bovine aortic endothelial cells using new fluore-scence indicators: diaminofluoresceins", FEBS Lett. 427, 263–266.
  • Itoh, Y, Ma, F.H., Hoshi, H., Oka, M., Noda, K., Ukai, Y., Kojima, H., Nagano, T. and Toda, N. (2000) "Determination and bioimaging method for nitric oxide in biological specimens by diaminofluorescein fluorometry", Anal. Bio-chem. 287, 203–209.
  • Zweier, J.L., Wang, P., Samouilov, A. and Kuppusamy, P. (1995) "Enzyme-independent formation of nitric oxide in biological tissues", Nat. Med. 1, 804–809.
  • Dahn, H., Loewe, L. and Bunton, CA. (1960) "Ober die Oxydation von Ascorbinsdure durch salpetrige Satire. Teil VI: Ubersicht und Diskussion der Ergebnisse", Hely. Chim. Acta 43, 320–333.
  • Heller, R., Milinscher-Paulig, F., Gräbner, R. and Till, U. (1999) "L-ascorbic acid potentiates nitric oxide synthesis in endothelial cells", J. Biol. Chem. 274, 8254–8260.
  • Heller, R., Unbehaun, A., Schellenberg, B., Mayer, B., Werner-Felmayer, G. and Werner, E.R. (2001) "L-Ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin", J. Biol. Chem. 276, 40–47.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.