522
Views
103
CrossRef citations to date
0
Altmetric
Original Article

Extracellular 8-oxo-dG as a sensitive parameter for oxidative stress in vivo and in vitro

, , , &
Pages 153-162 | Received 10 Sep 2004, Published online: 07 Jul 2009

References

  • Dizdaroglu M, Jaruga P, Birincioglu M, Rodriguez H. Free radical-induced damage to DNA: Mechanisms and measure-ment. Free Radic Biol Med 2002;32:1102–1115.
  • ESCODD Measurement of DNA oxidation in human cells by chromatographic and enzymic methods. Free Radic Biol Med 2003;34:1089–1099.
  • Sokhansanj BA, Wilson DM, 3rd. Oxidative DNA damage background estimated by a system model of base excision repair. Free Radic Biol Med 2004;37: 422–427.
  • Loft S, Poulsen HE. Cancer risk and oxidative DNA damage in man. J Mol Med 1996;74:297–312.
  • Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: Mechanisms, mutation, and disease. Faseb J 2003;17:1195–1214.
  • Stevnsner T, Thorslund T, de Souza-Pinto NC, Bohr VA. Mitochondrial repair of 8-oxoguanine and changes with aging. Exp Gerontol 2002;37: 1189–1196.
  • Goodhead DT. Initial events in the cellular effects of ionizing radiations: Clustered damage in DNA. Int J Radiat Biol 1994;65:7–17.
  • Czene S, Harms-Ringdahl M. Detection of single-strand breaks and formamidopyrimidine-DNA glycosylase-sensitive sites in DNA of cultured human fibroblasts. Mutat Res 1995;336:235–242.
  • Pouget JP, Ravanat JL, Douki T, Richard MJ, Cadet J. Measurement of DNA base damage in cells exposed to low doses of gamma-radiation: Comparison between the HPLC-EC and comet assays. hit J Radiat Biol 1999;75:51–58.
  • Le XC, Xing JZ, Lee J, Leadon SA, Weinfeld M. Inducible repair of thymine glycol detected by an ultrasensitive assay for DNA damage. Science 1998;280:1066–1069.
  • Dizdaroglu M. Formation of an 8-hydroxyguanine moiety in deoxyribonucleic acid on gamma-irradiation in aqueous solution. Biochemistry 1985;24:4476–4481.
  • Pouget JP, Frelon S, Ravanat JL, Testard I, Odin F, Cadet J. Formation of modified DNA bases in cells exposed either to gamma radiation or to high-LET particles. Radiat Res 2002;157:589–595.
  • Kasai H, Nishimura S. Hydroxylation of guanine in nucleo-sides and DNA at the C-8 position by heated glucose and oxygen radical-forming agents. Environ Health Perspect 1986;67:111–116.
  • Giese B. Long-distance charge transport in DNA: The hopping mechanism. Acc Chem Res 2000;33:631–636.
  • Slupphaug G, Kavli B, Krokan HE. The interacting pathways for prevention and repair of oxidative DNA damage. Mutat Res 2003;531:231–251.
  • Lunec J, Holloway KA, Cooke MS, Faux S, Griffiths HR, Evans MD. Urinary 8-oxo-2'-deoxyguano51ne: redox regu-lation of DNA repair in vivo? Free Radic Biol Med 2002;33:875–885.
  • Gros L, Saparbaev MK, Laval J. Enzymology of the repair of free radicals-induced DNA damage. Oncogene 2002;21:8905–8925.
  • Cadet J, Douki T, Gasparutto D, Ravanat JL. Oxidative damage to DNA: Formation, measurement and biochemical features. Mutat Res 2003;531:5–23.
  • Evans MD, Dizdaroglu M, Cooke MS. Oxidative DNA damage and disease: Induction, repair and significance. Mutat Res 2004;567:1–61.
  • Hayakawa H, Taketomi A, Sakumi K, Kuwano M, Sekiguchi M. Generation and elimination of 8-oxo-7,8-dihydro-2'-deoxygua-nosine 5'-triphosphate, a mutagenic substrate for DNA synthesis, in human cells. Biochemistry 1995;34: 89–95.
  • Nakabeppu Y. Molecular genetics and structural biology of human MutT homolog, MTH1. Mutat Res 2001;477:59–70.
  • Shigenaga MK, Gimeno CJ, Ames BN. Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage. Proc Natl Acad Sci USA 1989;86: 9697–9701.
  • Kasai H. Chemistry-based studies on oxidative DNA damage: Formation, repair, and mutagenesis. Free Radic Biol Med 2002;33:450–456.
  • Tagesson C, Kallberg M, Klintenberg C, Starkhammar H. Determination of urinary 8-hydroxydeoxyguanosine by auto-mated coupled-column high performance liquid chromato-graphy: A powerful technique for assaying in vivo oxidative DNA damage in cancer patients. Eur J Cancer 1995;31A:934–940.
  • Haghdoost S, Svoboda P, Naslund I, Harms-Ringdahl M, Tilikides A, Skog S. Can 8-oxo-dG be used as a predictor for individual radiosensitivity? hit J Radiat Oncol Biol Phys 2001;50: 405–410.
  • Bialkowski K, Kowara R, Windorbska W, Olinski R. 8-0xo-2'-deoxyguanosine level in lymphocytes DNA of cancer patients undergoing radiotherapy. Cancer Lett 1996;99:93–97.
  • Foksinski M, Gackowski D, Rozalski R, Olinski R. Cellular level of 8-oxo-2'-deoxyguanosine in DNA does not correlate with urinary excretion of the modified base/nucleoside. Acta Biochim Pol 2003;50:549–553.
  • Weimann A, Belling D, Poulsen HE. Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectro-metry. Nucleic Acids Res 2002;30:E7.
  • Cooke MS, Lunec J, Evans MD. Progress in the analysis of urinary oxidative DNA damage. Free Radic Biol Med 2002;33:1601–1614.
  • Simic MG. Urinary biomarkers and the rate of DNA damage in carcinogenesis and anticarcinogenesis. Mutat Res 1992;267:277–290.
  • Shigenaga MK, Ames BN. Assays for 8-hydroxy-2'-deoxygua-nosine: A biomarker of in vivo oxidative DNA damage. Free Radic Biol Med 1991;10:211–216.
  • Helbock HJ, Beckman KB, Shigenaga MK, Walter PB, Woodall AA, Yeo HC, Ames BN. DNA oxidation matters: The HPLC-electrochemical detection assay of 8-oxo-deoxyguano-sine and 8-oxo-guanine. Proc Natl Acad Sci USA 1998;95: 288–293.
  • Cooke MS, Evans MD, Lunec J. DNA repair: Insights from urinary lesion analysis. Free Radic Res 2002;36:929–932.
  • Czene S, Testa E, Nygren J, Belyaev I, Harms-Ringdahl M. DNA fragmentation and morphological changes in apoptotic human lymphocytes. Biochem Biophys Res Commun 2002;294:872–878.
  • Toyokuni S, Tanaka T, Hattori Y, Nishiyama Y, Yoshida A, Uchida K, Hiai H, Ochi H, Osawa T. Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxy-guanosine by a monoclonal antibody N45.1: Its application to ferric nitrilotriacetate-induced renal carcinogenesis model. Lab Invest 1997;76: 365–374.
  • Dianov GL, Souza-Pinto N, Nyaga SG, Thybo T, Stevnsner T, Bohr VA. Base excision repair in nuclear and mitochondrial DNA. Prog Nucleic Acid Res Mol Biol 2001;68:285–297.
  • Weimann A, Riis B, Poulsen HE. Oligonucleotides in human urine do not contain 8-oxo-7,8-dihydrodeoxyguanosine. Free Radic Biol Med 2004;36: 1378–1382.
  • Ischenko AA, Saparbaev MK. Alternative nucleotide incision repair pathway for oxidative DNA damage. Nature 2002;415:183–187.
  • Maki H, Sekiguchi M. MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis. Nature 1992;355:273–275.
  • Furuichi M, Yoshida MC, Oda H, Tajiri T, Nakabeppu Y, Tsuzuki T, Sekiguchi M. Genomic structure and chromosome location of the human mutt homologue gene MTH1 encoding 8-oxo-dGTPase for prevention of A:T to C:G transversion. Genomics 1994;24: 485–490.
  • Mo JY, Maki H, Sekiguchi M. Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool. Proc Natl Acad Sci USA 1992;89: 11021–11025.
  • Zhao M, Antunes F, Eaton JW, Brunk UT. Lysosomal enzymes promote mitochondrial oxidant production, cyto-chrome c release and apoptosis. Eur J Biochem 2003;270: 3778–3786.
  • Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993;362:709–715.
  • Meijer AE, Saeidi AB, Zelenskaya A, Czene S, Granath F, Harms-Ringdahl M. Influence of dose-rate, post-irradiation incubation time and growth factors on interphase cell death by apoptosis and clonogenic survival of human peripheral lymphocytes. hit J Radiat Biol 1999;75:1265–1273.
  • Leach JK, Van Tuyle G, Lin P-S, Schmidt-Ullrich R, Mikkelsen RB. Ionizing radiation-induced mitochondria-dependent generation of reactive Oxygen/Nitrogen. Cancer Res 2001;61:3894–3901.
  • Allinson SL, Sleeth KM, Matthewman GE, Dianov GL. Orchestration of base excision repair by controlling the rates of enzymatic activities. DNA Repair (Amst) 2004;3:23–31.
  • Vicker MG, Bultmann H, Glade U, Hafker T. Ionizing radiation at low doses induces inflammatory reactions in human blood. Radiat Res 1991;128:251–257.
  • Shen ZL, Lassner F, Bader A, Becker M, Walter GF, Berger A. Cellular activity of resident macrophages during Wallerian degeneration. Microsurgery 2000;20:255–261.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.