The Adp-stimulated Nadph Oxidase Activates The Ask-1/mkk4/jnk Pathway In Alveolar Macrophages

References

• Nauseef WM. Assembly of the phagocyte NADPH oxidase. Histochem Cell Biol 2004
   PubMed Web of Science ®Google Scholar
• Lambeth JD. NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 2004; 4: 181–189
   PubMed Web of Science ®Google Scholar
• Forman HJ, Torres M. Signaling by the respiratory burst in macrophages. IUBMB Life 2001; 51: 365–371
   PubMed Web of Science ®Google Scholar
• Simeonova PP, Luster MI. Iron and reactive oxygen species in the asbestos-induced tumor necrosis factor-alpha response from alveolar macrophages. Am J Respir Cell Mol Biol 1995; 12: 676–683
   PubMed Web of Science ®Google Scholar
• Gossart S, Cambon C, Orfila C, Seguelas M, Lepert J, Rami J, Carre P, Pipy B. Reactive oxygen intermediates as regulators of TNF-a production in rat lung inflammation induced by silica. J Immunol 1996; 156: 1540–1548
   PubMed Web of Science ®Google Scholar
• Kaul N, Forman HJ. Activation of NF-κB by the respiratory burst of macrophages. Free Radic Biol Med 1996; 21: 401–405
   PubMed Web of Science ®Google Scholar
• Iles KE, Dickinson DA, Watanabe N, Iwamoto T, Forman HJ. AP-1 activation through endogenous H(2)O(2) generation by alveolar macrophages. Free Radic Biol Med 2002; 32: 1304–1313
   PubMed Web of Science ®Google Scholar
• Torres M, Forman HJ. Activation of several MAP kinases upon stimulation of rat alveolar macrophages: Role of the NADPH oxidase. Arch Biochem Biophys 1999; 366: 231–239
   PubMed Web of Science ®Google Scholar
• Gozal E, Forman HJ, Torres M. ADP stimulates the respiratory burst without activation of ERK and AKT in rat alveolar macrophages. Free Radic Biol Med 2001; 31: 679–687
   PubMed Web of Science ®Google Scholar
• Forman HJ, Fukuto J, Torres M. Redox signaling—thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers. Am J Physiol Cell Physiol 2004; 287: C246–C256
   PubMed Web of Science ®Google Scholar
• Kabe Y, Ando K, Hirao S, Yoshida M, Handa H. Redox regulation of NF-κB activation: Distinct redox regulation between the cytoplasm and the nucleus. Antioxid Redox Signal 2005; 7: 395–403
   PubMed Web of Science ®Google Scholar
• Nakashima I, Takeda K, Kawamoto Y, Okuno Y, Kato M, Suzuki H. Redox control of catalytic activities of membrane-associated protein tyrosine kinases. Arch Biochem Biophys 2005; 434: 3–10
   PubMed Web of Science ®Google Scholar
• Zhang Y, Chen F. Reactive oxygen species (ROS), troublemakers between nuclear factor-κB (NF-κB) and c-Jun NH(2)-terminal kinase (JNK). Cancer Res 2004; 64: 1902–1905
   PubMed Web of Science ®Google Scholar
• Cross JV, Templeton DJ. Thiol oxidation of cell signaling proteins: Controlling an apoptotic equilibrium. J Cell Biochem 2004; 93: 104–111
   PubMed Web of Science ®Google Scholar
• Rhee SG, Chang TS, Bae YS, Lee SR, Kang SW. Cellular regulation by hydrogen peroxide. J Am Soc Nephrol 2003; 14: S211–S215
   PubMed Web of Science ®Google Scholar
• Stone JR. An assessment of proposed mechanisms for sensing hydrogen peroxide in mammalian systems. Arch Biochem Biophys 2004; 422: 119–124
   PubMed Web of Science ®Google Scholar
• Shaulian E, Karin M. AP-1 as a regulator of cell life and death. Nat Cell Biol 2002; 4: E131–E136
   PubMed Web of Science ®Google Scholar
• Drummond GR, Cai H, Davis ME, Ramasamy S, Harrison DG. Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide. Circ Res 2000; 86: 347–354
   PubMed Web of Science ®Google Scholar
• Torres M. Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 2003; 8: D369–D391
   PubMed Web of Science ®Google Scholar
• Takeda K, Hatai T, Hamazaki TS, Nishitoh H, Saitoh M, Ichijo H. Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells. J Biol Chem 2000; 275: 9805–9813
   PubMed Web of Science ®Google Scholar
• Wang XS, Diener K, Jannuzzi D, Trollinger D, Tan TH, Lichenstein H, Zukowski M, Yao Z. Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase. J Biol Chem 1996; 271: 31607–31611
   PubMed Web of Science ®Google Scholar
• Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep 2001; 2: 222–228
   PubMed Web of Science ®Google Scholar
• Matsuzawa A, Ichijo H. Stress-responsive protein kinases in redox-regulated apoptosis signaling. Antioxid Redox Signal 2005; 7: 472–481
   PubMed Web of Science ®Google Scholar
• Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 1998; 17: 2596–2606
   PubMed Web of Science ®Google Scholar
• Liu H, Nishitoh H, Ichijo H, Kyriakis JM. Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin. Mol Cell Biol 2000; 20: 2198–2208
   PubMed Web of Science ®Google Scholar
• Masters SC, Subramanian RR, Truong A, Yang H, Fujii K, Zhang H, Fu H. Survival-promoting functions of 14-3-3 proteins. Biochem Soc Trans 2002; 30: 360–365
   PubMed Web of Science ®Google Scholar
• Cho SG, Lee YH, Park HS, Ryoo K, Kang KW, Park J, Eom SJ, Kim MJ, Chang TS, Choi SY. Glutathione S-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1. J Biol Chem 2001; 276: 12749–12755, and others
   PubMed Web of Science ®Google Scholar
• Dorion S, Lambert H, Landry J. Activation of the p38 signaling pathway by heat shock involves the dissociation of glutathione S-transferase Mu from Ask1. J Biol Chem 2002; 277: 30792–30797
   PubMed Web of Science ®Google Scholar
• Stonehouse MJ, Cota-Gomez A, Parker SK, Martin WE, Hankin JA, Murphy RC, Chen W, Lim KB, Hackett M, Vasil AI. A novel class of microbial phosphocholine-specific phospholipases C. Mol Microbiol 2002; 46: 661–676, and others
   PubMed Web of Science ®Google Scholar
• Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science 1998; 281: 1860–1863
   PubMed Web of Science ®Google Scholar
• Song JJ, Rhee JG, Suntharalingam M, Walsh SA, Spitz DR, Lee YJ. Role of glutaredoxin in metabolic oxidative stress. Glutaredoxin as a sensor of oxidative stress mediated by H2O2. J Biol Chem 2002; 277: 46566–46575
   PubMed Web of Science ®Google Scholar
• Holmgren A. Thiols of thioredoxin and glutaredoxin in redox signaling. Signal transduction by reactive oxygen and nitrogen species: Pathways and chemical principles, HJ Forman, J Fukuto, M Torres. Boston: Kluwer Academic Publishers, Dordrecht 2003; 33–52
   Google Scholar
• Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K, Gotoh Y. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997; 275: 90–94
   PubMed Web of Science ®Google Scholar
• Song JJ, Lee YJ. Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1. Biochem J 2003; 373: 845–853
   PubMed Web of Science ®Google Scholar
• Tobiume K, Saitoh M, Ichijo H. Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer. J Cell Physiol 2002; 191: 95–104
   PubMed Web of Science ®Google Scholar
• Zhang L, Chen J, Fu H. Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins. Proc Natl Acad Sci USA 1999; 96: 8511–8515
   PubMed Web of Science ®Google Scholar
• Miele L, Cordella-Miele E, Xing M, Frizzell R, Mukherjee AB. Cystic fibrosis gene mutation (DF508) is associated with an intrinsic abnormality in Ca2+-induced arachidonic acid release by epithelial cells. DNA Cell Biol 1997; 16: 749–759
   PubMed Web of Science ®Google Scholar
• Subramanian RR, Zhang H, Wang H, Ichijo H, Miyashita T, Fu H. Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins. Exp Cell Res 2004; 294: 581–591
   PubMed Web of Science ®Google Scholar
• Fujii K, Goldman EH, Park HR, Zhang L, Chen J, Fu H. Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034. Oncogene 2004; 23: 5099–5104
   PubMed Web of Science ®Google Scholar
• Murphy JK, Livingston FR, Gozal E, Torres M, Forman HJ. Stimulation of the rat alveolar macrophage respiratory burst by extracellular adenine nucleotides. Am J Respir Cell Mol Biol 1993; 9: 505–510
   PubMed Web of Science ®Google Scholar
• Giron-Calle J, Forman HJ. Phospholipase D and priming of the respiratory burst by H2O2 in NR8383 alveolar macrophages. Am J Respir Cell Mol Biol 2000; 23: 748–754
   PubMed Web of Science ®Google Scholar
• Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. Embo J 1998; 17: 2596–2606
   PubMed Web of Science ®Google Scholar
• Bersani NA, Merwin JR, Lopez NI, Pearson GD, Merrill GF. Protein electrophoretic mobility shift assay to monitor redox state of thioredoxin in cells. Methods Enzymol 2002; 347: 317–326
   PubMedGoogle Scholar
• Arner ES, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem 2000; 267: 6102–6109
   PubMedGoogle Scholar
• Poole LB, Karplus PA, Claiborne A. Protein sulfenic acids in redox signaling. Annu Rev Pharmacol Toxicol 2004; 44: 325–347
   PubMed Web of Science ®Google Scholar
• Derevianko A, Graeber T, D'Amico R, Simms HH. The role of neutrophil-derived oxidants as second messengers in interleukin 1beta-stimulated cells. Shock 1998; 10: 54–61
   PubMed Web of Science ®Google Scholar
• Kaul N, Choi J, Forman HJ. Transmembrane redox signaling activates NF-kappaB in macrophages. Free Radic Biol Med 1998; 24: 202–207
   PubMed Web of Science ®Google Scholar
• Xanthoudakis S, Miao G, Vang F, Pan Y-C, Curran T. Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J 1992; 11: 3323–3335
   PubMed Web of Science ®Google Scholar
• Xanthoudakis S, Curran T. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity. EMBO J 1992; 11: 653–665
   PubMed Web of Science ®Google Scholar
• Nakamura H, Nakamura K, Yodoi J. Redox regulation of cellular activation. Annu Rev Immunol 1997; 15: 351–369
   PubMed Web of Science ®Google Scholar
• Adler V, Yin Z, Fuchs SY, Benezra M, Rosario L, Tew KD, Pincus MR, Sardana M, Henderson CJ, Wolf CR. Regulation of JNK signaling by GSTp. Embo J 1999; 18: 1321–1334, and others
   PubMed Web of Science ®Google Scholar
• Elsby R, Kitteringham NR, Goldring CE, Lovatt CA, Chamberlain M, Henderson CJ, Wolf CR, Park BK. Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi. J Biol Chem 2003; 278: 22243–22249
   PubMed Web of Science ®Google Scholar
• Pantano C, Shrivastava P, McElhinney B, Janssen-Heininger Y. Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase. J Biol Chem 2003; 278: 44091–44096
   PubMedGoogle Scholar
• Veal EA, Findlay VJ, Day AM, Bozonet SM, Evans JM, Quinn J, Morgan BA. A 2-Cys peroxiredoxin regulates peroxide-induced oxidation and activation of a stress-activated MAP kinase. Mol Cell 2004; 15: 129–139
   PubMed Web of Science ®Google Scholar
• Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. 2001; 2: 222.
   Google Scholar
• Fleming Y, Armstrong CG, Morrice N, Paterson A, Goedert M, Cohen P. Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7. Biochem J 2000; 352(Pt 1)145–154
   PubMedGoogle Scholar
• Tournier C, Whitmarsh AJ, Cavanagh J, Barrett T, Davis RJ. The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases. Mol Cell Biol 1999; 19: 1569–1581
   PubMed Web of Science ®Google Scholar
• Tournier C, Dong C, Turner TK, Jones SN, Flavell RA, Davis RJ. MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines. Genes Dev 2001; 15: 1419–1426
   PubMed Web of Science ®Google Scholar
• Kim DK, Cho ES, Seong JK, Um HD. Adaptive concentrations of hydrogen peroxide suppress cell death by blocking the activation of SAPK/JNK pathway. J Cell Sci 2001; 114: 4329–4334
   PubMed Web of Science ®Google Scholar
• Zhang R, Al-Lamki R, Bai L, Streb JW, Miano JM, Bradley J, Min W. Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner. Circ Res 2004; 94: 1483–1491
   PubMed Web of Science ®Google Scholar
• Liu Y, Min W. Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner. Circ Res 2002; 90: 1259–1266
   PubMed Web of Science ®Google Scholar
• Machino T, Hashimoto S, Maruoka S, Gon Y, Hayashi S, Mizumura K, Nishitoh H, Ichijo H, Horie T. Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells. Crit Care Med 2003; 31: 2776–2781
   PubMed Web of Science ®Google Scholar
• Goldman EH, Chen L, Fu H. Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. J Biol Chem 2004; 279: 10442–10449
   PubMed Web of Science ®Google Scholar
• Hill KE, McCollum GW, Boeglin ME, Burk RF. Thioredoxin reductase activity is decreased by selenium deficiency. Biochem Biophys Res Commun 1997; 234: 293–295
   PubMed Web of Science ®Google Scholar
• Gromer S, Arscott LD, Williams CH, Jr, Schirmer RH, Becker K. Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds. J Biol Chem 1998; 273: 20096–20101
   PubMed Web of Science ®Google Scholar
• Almholt K, Tullin S, Skyggebjerg O, Scudder K, Thastrup O, Terry R. Changes in intracellular cAMP reported by a Redistribution assay using a cAMP-dependent protein kinase-green fluorescent protein chimera. Cell Signal 2004; 16: 907–920
   PubMed Web of Science ®Google Scholar
• Morita K, Saitoh M, Tobiume K, Matsuura H, Enomoto S, Nishitoh H, Ichijo H. Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress. Embo J 2001; 20: 6028–6036
   PubMed Web of Science ®Google Scholar
• Huang S, Shu L, Easton J, Harwood FC, Germain GS, Ichijo H, Houghton PJ. Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity. J Biol Chem 2004; 279: 36490–36496
   PubMed Web of Science ®Google Scholar
• Zhou G, Golden T, Aragon Honk, IV, anen RE. Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade. J Biol Chem 2004; 279: 46595–46605
   PubMed Web of Science ®Google Scholar
• Kutuzov MA, Andreeva AV, Voyno-Yasenetskaya TA. Regulation of apoptosis signal-regulating kinase 1 (ASK1) by polyamine levels via protein phosphatase 5. J Biol Chem 2005; 280: 25388–25395
   PubMed Web of Science ®Google Scholar
• Rhee SG, Chae HZ, Kim K. Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic Biol Med 2005; 38: 1543–1552
   PubMed Web of Science ®Google Scholar
• Wood ZA, Poole LB, Karplus PA. Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science 2003; 300: 650–653
   PubMed Web of Science ®Google Scholar
• Iles KE, Dickinson DA, Watanabe N, Iwamoto T, Forman HJ. AP-1 activation through endogenous H2O2 generation by alveolar macrophages. Free Radic Biol Med 2002; 32: 1304–1313
   PubMed Web of Science ®Google Scholar
• Guo RF, Lentsch AB, Sarma JV, Sun L, Riedemann NC, McClintock SD, McGuire SR, Van Rooijen N, Ward PA. Activator protein-1 activation in acute lung injury. Am J Pathol 2002; 161: 275–282
   PubMed Web of Science ®Google Scholar
• Fujii S, Nanbu Y, Konishi I, Mori T, Masutani H, Yodoi J. Immunohistochemical localization of adult T-cell leukaemia-derived factor, a human thioredoxin homologue, in human fetal tissues. Virchows Arch A Pathol Anat Histopathol 1991; 419: 317–326
   PubMedGoogle Scholar
• Helmke RJ, Boyd RL, German VF, Mangos JA. From growth factor dependence to growth factor responsiveness: The genesis of an alveolar macrophage cell line. In Vitro Cell Dev Biol 1987; 23: 567–574
   PubMed Web of Science ®Google Scholar
• Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248–254
   PubMed Web of Science ®Google Scholar