Pyruvate prevents hydrogen peroxide-induced apoptosis

References

• Bulkley G.B. The role of oxygen free radicals in human disease processes. Surgery 1983; 94: 407–411
   PubMed Web of Science ®Google Scholar
• Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine. Oxford Press, London 1989
   Google Scholar
• Markesbery W.R. Oxidative stress hypothesis in Alzheimer's disease. Free Radicals in Biology and Medicine 1997; 23: 134–147
   PubMed Web of Science ®Google Scholar
• Coyle J.T., Puttfarcken P. Oxidative stress, glutamate and neurodegenerative disorders. Science 1993; 262: 689–695
   PubMed Web of Science ®Google Scholar
• Palmer A.M., Burns M.A. Selective increase in lipid peroxidation in the inferior temporal cortex in Alzheimer's disease. Brain Research 1994; 645: 338–342
   PubMed Web of Science ®Google Scholar
• Van Der Zee J., Dubbelman T.M.A.R., Van Steveninck J. Peroxide-induced membrane damage in human erythrocytes. Biochimica et Biophysica Acta 1985; 818: 38–44
   PubMed Web of Science ®Google Scholar
• Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine. OxfordUK 1985; 1–346, In
   Google Scholar
• Fligiel S.E.G., Lee E.C., McCoy J.P., Johnson K.J., Varani J. Protein degradation following treatment with hydrogen peroxide. American Journal of Pathology 1984; 115: 418–425
   PubMed Web of Science ®Google Scholar
• Kako K., Kato M., Matsuoka T., Mustapha A. Depression of membrane-bound Na+-K+-ATPase activity induced by free radicals and by ischemia of kidney. American Journal of Physiology 1988; 254: C330–C337
   Google Scholar
• Jonas S.K., Riley P.A., Willson R.L. Hydrogen peroxide cytotoxicity. Biochemical Journal 1989; 264: 651–655
   PubMed Web of Science ®Google Scholar
• Duthie S.J., Collins A.R. The influence of cell growth, detoxifying enzymes and DNA repair on hydrogen-peroxide mediated DNA damage (measured using the comet assay) in human cells. Free Radicals in Biology and Medicine 1997; 22: 717–724
   PubMed Web of Science ®Google Scholar
• Lloyd R.V., Hanna P.M., Mason R.P. The origin of the hydroxyl radical oxygen in the Fenton reaction. Free Radicals in Biology and Medicine 1997; 22: 885–888
   PubMed Web of Science ®Google Scholar
• Gardner A.M., Xu F.H., Fady C., Jacoby F.J., Duffey D.C., Tu Y., Lichtenstein A. Apoptotic vs non-apoptotic cytotoxicity induced by hydrogen peroxide. Free Radicals in Biology and Medicine 1997; 22: 73–83
   PubMed Web of Science ®Google Scholar
• Lennon S.V., Martin S.J., Cotter T.G. Dose-dependent induction of apoptosis in human tumor cell lines by widely diverging stimuli. Cell Proliferation 1991; 24: 203–214
   PubMed Web of Science ®Google Scholar
• Forrest V.J., Kang Y.H., McClain D.E., Robinson D.H., Ramakrishnan N. Oxidative stress-induced apoptosis prevented by trolox. Free Radicals in Biology and Medicine 1994; 16: 675–684
   PubMed Web of Science ®Google Scholar
• de Bono D.P., Yang W.D. Exposure to low concentrations of hydrogen peroxide causes delayed endothelial cell death and inhibits proliferation of surviving cells. Atherosclerosis 1995; 114: 235–245
   PubMed Web of Science ®Google Scholar
• Wyllie A.H., Kerr J.F.R., Currie A.R. Cell death: the significance of apoptosis. International Review of Cytology 1980; 68: 251–262
   PubMedGoogle Scholar
• Morris R.G., Hargreaves A.D., Duval E., Wyllie A.H. Hormone-induced death. II. Surface changes in thymocytes undergoing apoptosis. American Journal of Pathology 1984; 115: 426–431
   PubMed Web of Science ®Google Scholar
• Savill J.S., Fadok V., Henson P., Haslett C. Phagocyte recognition of cells undergoing apoptosis. Immunology Today 1993; 14: 131–136
   PubMedGoogle Scholar
• Buttke T.M., Sandstrom P.A. Oxidative stress as a mediator of apoptosis. Immunology Today 1994; 15: 7–10
   PubMedGoogle Scholar
• Kroemer G., Martinez C.A. Pharmacological inhibition of programmed lymphocyte death. Immunology Today 1994; 15: 235–242
   PubMedGoogle Scholar
• Thompson C.B. Apoptosis in the pathogenesis and treatment of disease. Science 1995; 267: 1456–1462
   PubMed Web of Science ®Google Scholar
• Cohen J.J. Apoptosis: The physiologic pathway of cell death. Hospital Practice 1993; 28: 35–43
   Web of Science ®Google Scholar
• Tanaka M., Ito H., Adachi S., Akimoto H., Nishikawa T., Kasajima T., Marumo F., Hiroe M. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultures of neonatal rat cardiomyocytes. Circulatory Research 1994; 75: 426–433
   PubMed Web of Science ®Google Scholar
• Rosenbaum D.M., Kalberg J., Kessler J.A. Superoxide dismutase ameliorates neuronal death from hypoxia in culture. Stroke 1994; 25: 857–863
   PubMedGoogle Scholar
• Gottlieb R.A., Burleson K.O., Kloner R.A., Babior B.M., Engler R.L. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. Journal of Clinical Investigation 1994; 94: 1621–1628
   PubMed Web of Science ®Google Scholar
• Ramakrishnan N., Kalinich J.F., McClain D.E. Ebselen inhibition of apoptosis by reduction of peroxides. Biochemical Pharmacology 1996; 51: 1443–1451
   PubMed Web of Science ®Google Scholar
• Holleman A.F. Notice sur I′ action de I′ eau oxygenee sur les acides acetoniques et surr les Dicetones 1.2. Recueil Travaux Chimiques Pays-Bas Belgique 1904; 23: 169–171
   Google Scholar
• Bünger R., Swindall B., Brodie D., Zdunek D., Stiegler H., Walter G. Pyruvate attenuation of hypoxia damage in isolated working guinea-pig heart. Journal of Molecular Cell Cardiology 1986; 18: 423–438
   PubMedGoogle Scholar
• Bünger R., Mallet R.T., Hartman D.A. Pyruvateenhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Nearcomplete prevention of reperfusion contractile failure. European Journal of Biochemistry 1989; 180: 221–233
   PubMedGoogle Scholar
• Deboer L.W.V., Bekx P.A., Han L., Steinke L. Pyruvate enhances recovery of rat hearts after ischemia and reperfusion by preventing free radical generation. American Journal of Physiology 1993; 34: H1571–H1576
   Google Scholar
• Salahudeen A.K., Clark E.C., Nath K.A. Hydrogen peroxide-induced renal injury. A protective role for pyruvate in vitro and in vivo. Journal of Clinical Investigation 1991; 88: 1886–1893
   PubMed Web of Science ®Google Scholar
• Ramakrishnan N., McClain D.E., Catravas G.N. Membranes as sensitive targets in thymocyte apoptosis. International Journal of Radiation Biology 1993; 63: 693–701
   PubMed Web of Science ®Google Scholar
• Gong J., Traganos F., Darzynkiewicz Z. A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Analytical Biochemistry 1994; 218: 314–319
   PubMed Web of Science ®Google Scholar
• Fadok V.A., Voelker D.R., Campbell P.A., Cohen J.J., Bratton D.L., Henson P.M. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. Journal of Immunology 1992; 148: 2207–2216
   PubMed Web of Science ®Google Scholar
• Fadok V.A., Savill J.S., Haslett C., Bratton D.L., Doherry D.E., Campbell P.A., Henson P.M. Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells. Journal of Immunology 1992; 149: 4029–4035
   PubMed Web of Science ®Google Scholar
• Fadok V.A., Laszlo D.J., Noble P.W., Weinstein L., Riches D.W.H., Henson P.M. Particle digestibility is required for induction of phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells. Journal of Immunology 1993; 151: 4274–4285
   PubMedGoogle Scholar
• Martin S.J., Reutelingsperger C.P.M., McGahon A.J., Rader J.A., vanSchie R.C.A.A., LaFace D.M., Green D.R. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by over expression of Bcl-2 and Abl. Journal of Experimental Medicine 1995; 182: 1545–1556
   PubMed Web of Science ®Google Scholar
• Tait J.F., Gibson D., Fujikawa K. Phospholipid binding properties of human placental anticoagulant protein-I, a member of the lipocortin family. Journal of Biological Chemistry 1989; 264: 7944–7949
   PubMedGoogle Scholar
• Andree H.A.M., Reutelingsperger C.P.M., Hauptmann R., Hemker H.C., Hermens W.T., Willems G.M. Binding of vascular anticoagulant α (VACα) to planar phospholipid bilayers. Journal of Biological Chemistry 1990; 265: 4923–4928
   PubMed Web of Science ®Google Scholar
• Thiagarajan P., Tait T.F. Binding of annexin V/placental anticoagulant protein I to platelets. Evidence for phosphatidylserine exposure in the procoagulant response of activated platelets. Journal of Biological Chemistry 1990; 265: 17420–17423
   PubMedGoogle Scholar
• Sellins K.S., Cohen J.J. Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. Journal of Immunology 1987; 139: 3199–3207
   PubMed Web of Science ®Google Scholar
• Kroemer G., Petit P., Zamzami N., Vayssiere J.L., Mignote B. The biochemistry of programmed cell death. FASEB Journal 1995; 9: 1277–1287
   PubMed Web of Science ®Google Scholar
• Chou C.C., Lam C.Y., Yung B.Y.M. Intracellular ATP is required for actinomycin D-induced apoptotic cell death in HeLa cells. Cancer Letters 1995; 96: 181–187
   PubMed Web of Science ®Google Scholar
• Zamzami N., Marchetti P., Castedo M., Decaudin D., Macho A., Hirsch R., Susin S.A., Petit P.X., Mignotte B., Kroemer G. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. Journal of Experimental Medicine 1995; 182: 367–377
   PubMed Web of Science ®Google Scholar
• Mallet R.T., Bünger R. Energetic modulation of cardiac inotropism and sarcoplasmic reticular calcium uptake. Biochimica et Biophysica Acta 1994; 1224: 22–32
   PubMedGoogle Scholar
• Martin B.J., Lasley R.D., Bünger R., Mentzer R.M., Jr. Pyruvate augments calcium transients and cell shortening in rat ventricular myocytes. American Journal of Physiology 1998; 274: H8–H17
   Google Scholar
• Clough D., Bünger R. Protection of pyruvate against inhibition of Na+-K+-ATPase by a free radical generating system containing t-butylhydroperoxide. Life Sciences 1995; 57: 931–943
   PubMedGoogle Scholar
• Buttke T.M., Sandstrom P.A. Redox regulation of programmed cell death in lymphocytes. Free Radical Research 1995; 22: 389–397
   PubMed Web of Science ®Google Scholar
• Pepera A., Parkes H.G., Herz H., Haycock P., Blake D.P., Grootveld M.C. High resolution 1H NMR investigations of the reactivities of α-keto acid anions with hydrogen peroxide. Free Radical Research 1997; 26: 145–157
   PubMedGoogle Scholar
• Giandomenico A.R., Cerniglia G.E., Biaglow J.E., Stevens C.W., Koch C.J. The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide. Free Radical in Biology and Medicine 1997; 23: 426–434
   PubMed Web of Science ®Google Scholar
• Herz H., Blake D.R., Grootveld M. Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: The roles of endogenous pyruvate and lactate. Free Radical Research 1997; 26: 19–35
   PubMed Web of Science ®Google Scholar
• Sandstrom P.A., Buttke T.M. Autocrine production of extracellular catalase prevents apoptosis of the human CEM T-cell line in serum-free medium. Proceedings of the National Academy of Sciences USA 1993; 89: 7924–7928
   Google Scholar
• Bünger R., Mallet R.T. Mitochondrial pyruvate transport in working guinea-pig heart. Work-related vs carrier-mediated control of pyruvate oxidation. Biochimica et Biophysica Acta 1993; 1151: 223–236
   PubMedGoogle Scholar
• Kang Y.H., Mallet R.T., Bünger R. Coronary autoregulation and purine release in normoxic heart at various cytoplasmic phosphorylation potentials: Disparate effects of adenosine. European Journal of Physiology 1992; 421: 188–199
   PubMedGoogle Scholar
• Dijkstra U., Gabreels F., Joosten E., Wevers R., Lamers K., Doesburg W., Renier W. Friedreich's ataxia: Intravenous pyruvate load to demonstrate a defect in pyruvate metabolism. Neurology 1984; 34: 1493–1497
   PubMed Web of Science ®Google Scholar
• Hasenfuss G. Influence of pyruvate on hemodynamics and calcium cycling in failing human hearts. Circulation (supplement) 1997; 96: I–524
   Google Scholar