2,818
Views
155
CrossRef citations to date
0
Altmetric
Research Article

Polyacrylamide-Chitosan Hydrogels: In Vitro Biocompatibility and Sustained Antibiotic Release Studies

Pages 69-75 | Published online: 29 Sep 2008

References

  • Blanco, M. D., Garcia, O., Olmo, R., Teijon, J. M., and Katime, I. 1996. Release of 5-fluorouracil from poly(acrylamide-co-monopropy l itaconate) hydrogels. J. Chromatog r. B. Biomed. Appl. 680:243–253.
  • Chandy, T., and Sharma, C. P. 1993. Chitosan matrix for oral sustained delivery of ampicillin. Biomaterials 14:939–944.
  • Chandy, T., and Sharma, C. P. 1992. Glucose responsive insulin release from poly(vinyl alcohol)-blended polyacrylamide membranes containing glucose oxidase. J. Appl. Polym. Sci. 46:1159–1167.
  • Chen, J., Haesun, P., and Park, K. 1999. Synthesis of superporous hydrogels: hydrogels with fast swelling and superabsorban t properties. J. Biomed. Mater. Res. 44:53–62.
  • Davis, B. K., Noske, L., and Chang, M. C. 1972. Reproductive performanc e of hamsters with polyacrylamide implants containing ethinylestradiol. Acta Endocrinol. 70:385.
  • Doyle, A., Grifiths, J. B., and Newell, D. G., eds. 1995. Cell and tissue culture: laboratory procedure s. New York: John Wiley & Sons.
  • Hari, P. R., Chandy, T., and Sharma, C. P. 1996. Chitosan/calcium alginate beads for oral delivery of insulin. J. App. Polym Sci. 59:1795–1801.
  • Hou, W. M., Miyazaki, S., Takada, M., and Komai, T. 1985. Sustained re- lease of indomethaci n from chitosan granules. Chem. Pharm. Bull. 33:3986– 3992.
  • Itokazu, M., Yamemoto, K., Yang, W. Y., Aoki, T., Kato, N., and Watanabe, K. 1997. The sustained release of antibiotics from freeze-dried ibrin-antibiotic compoun d and eficacies in rat model of osteomyelitis. Infection 25:359–363.
  • Karadag, E., Saraydin, D., Cetinkaya, S., and Guven, O. 1996. In vitro swelling studies and preliminary biocompatibility evaluation of acrylamide-base d hy- drogels. Biomaterials 17:67–70.
  • Miekka, S., Jameson, T., Woolverton, C., Lin, H. M., Krajcik, R., Macphee, M., and Drohan, W. N. 1998. Novel delivery system for coagulation proteins. Haemophilia 4:436–442.
  • Muzzarelli, R., Baldassarre, V., Conti, F., Ferrara, P., Biagini, G., Gazzanelli, G., and Vasi, V. 1988. Biological activity of chitosan: ultrastructural study. Biomaterials 9:247–252.
  • Patel, V. R., and Amiji, M. M. 1996. Preparation and characterisation of freeze- dried chitosan poly(ethylene oxide) hydrogels for site speciic antibiotic de- livery in the stomach. Pharm. Res. 13:588–593.
  • Ratner, B. D. 1981. Biomedical applications of hydrogels: review and criti- cal appraisal. In Biocompatibility of clinical implant materials II, ed. D. F. Williams, 146. Boca Raton, Florida: CRC Press.
  • Remunan-Lopez, C., Lorenzo-Lamosa, M. L., Vila-Jato, J. L., and Alonso, M. J. 1998. Development of new chitosan-cellulose multicore microcapsules for controlled drug delivery. Eur. J. Pharm. Biopharm. 45:49–56.
  • Rosiak, J., Burchak, K., and Pekala, W. 1983. Polyacrylamide hydrogel s as sustained release drug delivery dressing material. Radiat. Phys. Chem. 22:907.
  • Shalaby, W. S., Peck, G. E., and Park, K. 1991. Release of dextomethopha n hydrobromid e from freeze-dried enzyme degradabl e hydrogels. J. Controlled Rel. 16:355–364.
  • Sing, U. V., and Udupa, N. 1998. Methotrexate loaded chitosan and chitin microcapsules—in vitro characterisation and pharmacokinetic s in mice bear- ing Ehrlich ascites carcinoma. J. Microencapsul. 15:581–594.
  • Uyen, H., Schakenraad, J. M., Sjollema, J., Noordmans, J., Jongebloed, W. L., Stokroos, I., and Busscher, H. J. 1990. Amount and surface structure of albu- min absorbed to solid substrata with different wettabilities in a parallel plate flow cell. J. Biomed. Mater. Res. 24:1599–1614.
  • Yao, K. D., Peng, T., Feng, H. B., and He, Y. Y. 1994. Swelling kinet- ics and release characteristic of crosslinked chitosan: polyether polymer network (semi-IPN) hydrogels. J. Polym. Sci. A: Polym. Chem. 32:1213–1223.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.