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Research Article

Improving the Dissolution Rate of Poorly Water Soluble Drug by Solid Dispersion and Solid Solution—Pros and Cons

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Pages 33-45 | Received 03 Oct 2005, Accepted 15 Dec 2005, Published online: 10 Oct 2008

REFERENCES

  • Goldberg A. H., Gibaldi M., Kanig J. L. Increasing dissolution rates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures. I-theoretical considerations and discussion of the literature. J. Pharmaceut. Sci. 1965; 54: 1145–1148
  • Goldberg A. H., Gibaldi M., Kanig J. L. Increasing dissolution rates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures. II-experimental evaluation of eutectic mixtures: urea-acetoaminophen system. J. Pharmaceut. Sci. 1966a; 55: 482–487
  • Goldberg A. H., Gibaldi M., Kanig J. L. Increasing dissolution rates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures. III-Experimental evaluation of griseofulvin-succinic acid solution. J. Pharmaceut. Sci. 1966b; 55: 487–492
  • Hammad M. A., Muller B. W. Solubility and stability of clonazepam in mixed Micelles. Int. J. Pharmaceut. 1998; 169: 55–64
  • Leuner C., Dressman J. Improving drug solubility for oral delivery using solid solutions. Eur. J. Pharmaceut. Biopharmaceut. 2000; 50: 47–60
  • Lipinski C. A., Lombardo F., Dominyl B. W., Feeney P. J. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Del. Rev. 1997; 23: 3–25
  • Martin A. Thermal analysis. Physical Pharmacy. Lea & Febiger, Philadelphia 1993, (8′)-88
  • Sekiguchi K., Obi N. Studies on absorption of eutectic mixture. I. A comparison of the behavior of eutectic mixture of sulfathiazole and that of ordinary sulfathiazole in man. Chem. Pharmaceut. Bull. 1961; 9: 866–872
  • Sekikawa H., Nakano M., Arita T. Inhibitory effect polyvinylpyrrolidone on the crystallization of drugs. Chem. Pharmaceut. Bull. 1978; 26: 118–126
  • Simonelli A. P., Metha S. C., Higuchi W. I. Inhibition of sulfathaizole crystal growth by poluvinylpyrrolidone (PVP). J. Pharmaceut. Sci. 1970; 59: 633–637

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