3,289
Views
55
CrossRef citations to date
0
Altmetric
Research Article

Investigation of the transport and absorption of Angelica sinensis polysaccharide through gastrointestinal tract both in vitro and in vivo

, , , , , , & show all
Pages 1360-1371 | Received 20 Jul 2017, Accepted 31 Aug 2017, Published online: 18 Sep 2017

References

  • Artursson P, Palm K, Luthman K. (2001). Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv Drug Deliv Rev 46:27–43.
  • Barthe L, Woodley J, Lavit M, et al. (2004). In vitro intestinal degradation and absorption of chondroitin sulfate, a glycosaminoglycan drug. Arzneimittelforschung 54:286–92.
  • Ben-Dov N, Korenstein R. (2013). Actin-cytoskeleton rearrangement modulates proton-induced uptake. Exp Cell Res 319:946–54.
  • Billat P-A, Roger E, Faure S, Lagarce F. (2017). Models for drug absorption from the small intestine: where are we and where are we going? Drug Discov Today 22:761–775.
  • Cai H, Yang X, Cai Q, et al. (2017). Lycium barbarum L. polysaccharide (LBP) reduces glucose uptake via down-regulation of SGLT-1 in Caco2 cell. Molecules 22:341.
  • Cao W, Li X-Q, Liu L, et al. (2006). Structure of an anti-tumor polysaccharide from Angelica sinensis (Oliv.) Diels. Carbohydr Polym 66:149–59.
  • Cartwright L, Poulsen MS, Nielsen HM, et al. (2012). In vitro placental model optimization for nanoparticle transport studies. Int J Nanomed 7:497.
  • Chae SY, Jang M-K, Nah J-W. (2005). Influence of molecular weight on oral absorption of water soluble chitosans. J Control Release 102:383–94.
  • Chao W-W, Lin B-F. (2011). Bioactivities of major constituents isolated from Angelica sinensis (Danggui). Chin Med 6:29.
  • Chen J, Pang W, Shi W, et al. (2016). Structural elucidation of a novel polysaccharide from Pseudostellaria heterophylla and stimulating glucose uptake in cells and distributing in rats by oral. Molecules 21:1233.
  • Conner SD, Schmid SL. (2003). Regulated portals of entry into the cell. Nature 422:37.
  • Deng S, Chen S-N, Yao P, et al. (2006). Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. J Nat Prod 69:536–41.
  • Devadas D, Koithan T, Diestel R, et al. (2014). Herpes simplex virus internalization into epithelial cells requires Na+/H+ exchangers and p21-activated kinases but neither clathrin- nor caveolin-mediated endocytosis. J Virol 88:13378–95.
  • Dog TL. (2005). Menopause: a review of botanical dietary supplements. Am J Med 118:98–108.
  • Domínguez-Avila JA, Wall-Medrano A, Velderrain-Rodríguez GR, et al. (2017). Gastrointestinal interactions, absorption, splanchnic metabolism and pharmacokinetics of orally ingested phenolic compounds. Food Funct 8:15–38.
  • Dong X, Chen H, Qin J, et al. (2017). Thermosensitive porphyrin-incorporated hydrogel with four-arm PEG-PCL copolymer (II): doxorubicin loaded hydrogel as a dual fluorescent drug delivery system for simultaneous imaging tracking in vivo. Drug Deliv 24:641–50.
  • Duizer E, Gilde AJ, Versantvoort CH, Groten JP. (1999). Effects of cadmium chloride on the paracellular barrier function of intestinal epithelial cell lines. Toxicol Appl Pharmacol 155:117–26.
  • During A, Harrison EH. (2005). An in vitro model to study the intestinal absorption of carotenoids. Food Res Int 38:1001–8.
  • Flint HJ, Bayer EA, Rincon MT, et al. (2008). Polysaccharide utilization by gut bacteria: potential for new insights from genomic analysis. Nat Rev Micro 6:121.
  • Fu Q, Wang H, Xia M, et al. (2015). The effect of phytic acid on tight junctions in the human intestinal Caco-2 cell line and its mechanism. Eur J Pharm Sci 80:1–8.
  • Galindo-Rodriguez SA, Allemann E, Fessi H, Doelker E. (2005). Polymeric nanoparticles for oral delivery of drugs and vaccines: a critical evaluation of in vivo studies. Crit Rev Ther Drug Carrier Syst 22:419–464.
  • Giacco R, Costabile G, Riccardi G. (2016). Metabolic effects of dietary carbohydrates: the importance of food digestion. Food Res Int 88:336–41.
  • Hue JJ, Lee H-J, Jon S, et al. (2013). Distribution and accumulation of Cy5.5-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles in the tissues of ICR mice. J Vet Sci 14:473–9.
  • Hwang SR, Byun Y. (2014). Advances in oral macromolecular drug delivery. Expert Opin Drug Deliv 11:1955–67.
  • Iwasa A, Akita H, Khalil I, et al. (2006). Cellular uptake and subsequent intracellular trafficking of R8-liposomes introduced at low temperature. Biochim Biophys Acta (BBA)-Biomembranes 1758:713–20.
  • Jiang Y-P, Guo X-K, Chen Y. (2007). O-succinyl derivative of ι-carrageenan fragments: synthesis and characterization. Carbohydr Polym 68:457–64.
  • Kadlecova Z, Spielman SJ, Loerke D, et al. (2016). Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2. J Cell Biol 216:167–179.
  • Kowapradit J, Opanasopit P, Ngawhirunpat T, et al. (2010). Methylated N-(4-N,N-dimethylaminocinnamyl) chitosan enhances paracellular permeability across Caco-2 cells. Drug Deliv 17:301–12.
  • Lai M, Wang J, Tan J, et al. (2017). Preparation, complexation mechanism and properties of nano-complexes of Astragalus polysaccharide and amphiphilic chitosan derivatives. Carbohydr Polym 161:261–9.
  • Lee C-M, Jeong H-J, Yun K-N, et al. (2012). Optical imaging to trace near infrared fluorescent zinc oxide nanoparticles following oral exposure. Int J Nanomed 7:3203.
  • Licha K, Riefke B, Ntziachristos V, et al. (2000). Hydrophilic cyanine dyes as contrast agents for near-infrared tumor imaging: synthesis, photophysical properties and spectroscopic in vivo characterization. Photochem Photobiol 72:392–8.
  • Liu C, Li J, Meng FY, et al. (2010). Polysaccharides from the root of Angelica sinensis promotes hematopoiesis and thrombopoiesis through the PI3K/AKT pathway. BMC Complement Altern Med 10:79.
  • Liu Y, Tseng YC, Huang L. (2012). Biodistribution studies of nanoparticles using fluorescence imaging: a qualitative or quantitative method? Pharm Res 29:3273–7.
  • Loehry C, Kingham J, Baker J. (1973). Small intestinal permeability in animals and man. Gut 14:683–8.
  • Lundquist P, Artursson P. (2016). Oral absorption of peptides and nanoparticles across the human intestine: opportunities, limitations and studies in human tissues. Adv Drug Deliv Rev 106:256–76.
  • Luo YY, Xiong XY, Tian Y, et al. (2016). A review of biodegradable polymeric systems for oral insulin delivery. Drug Deliv 23:1882–91.
  • Maisel K, Ensign L, Reddy M, et al. (2015). Effect of surface chemistry on nanoparticle interaction with gastrointestinal mucus and distribution in the gastrointestinal tract following oral and rectal administration in the mouse. J Control Release 197:48–57.
  • Michell C, Lahaye M, Bonnet C, et al. (1996). In vitro fermentation by human faecal bacteria of total and purified dietary fibres from brown seaweeds. Br J Nutr 75:263–80.
  • Mizukami S. (2017). Targetable fluorescent sensors for advanced cell function analysis. J Photochem Photobiol C: Photochem Rev 30:24–35.
  • Nagamine T, Nakazato K, Tomioka S, et al. (2014). Intestinal absorption of fucoidan extracted from the brown seaweed, Cladosiphon okamuranus. Marine Drugs 13:48–64.
  • Pranatharthiharan S, Patel MD, Malshe VC, et al. (2017). Asialoglycoprotein receptor targeted delivery of doxorubicin nanoparticles for hepatocellular carcinoma. Drug Deliv 24:20–9.
  • Qiao H, Fang D, Chen J, et al. (2017). Orally delivered polycurcumin responsive to bacterial reduction for targeted therapy of inflammatory bowel disease. Drug Deliv 24:233–42.
  • Reintjes G, Arnosti C, Fuchs BM, Amann R. (2017). An alternative polysaccharide uptake mechanism of marine bacteria. ISME J 11:1640–50.
  • Riezman H, Woodman PG, Van Meer G, Marsh M. (1997). Molecular mechanisms of endocytosis. Cell 91:731–8.
  • Sahay G, Alakhova DY, Kabanov AV. (2010). Endocytosis of nanomedicines. J Control Release 145:182–95.
  • Salama NN, Eddington ND, Fasano A. (2006). Tight junction modulation and its relationship to drug delivery. Adv Drug Deliv Rev 58:15–28.
  • Sokolis DP. (2017). Experimental study and biomechanical characterization for the passive small intestine: identification of regional differences. J Mech Behav Biomed Mater 74:93–105.
  • Sun Y, Cui SW, Tang J, Gu X. (2010). Structural features of pectic polysaccharide from Angelica sinensis (Oliv.) Diels. Carbohydr Polym 80:544–50.
  • Surampalli G, Nanjwade BK, Patil PA. (2016). Safety evaluation of naringenin upon experimental exposure on rat gastrointestinal epithelium for novel optimal drug delivery. Drug Deliv 23:512–24.
  • Swaan PW. (1998). Recent advances in intestinal macromolecular drug delivery via receptor-mediated transport pathways. Pharm Res 15:826–34.
  • Tang BC, Dawson M, Lai SK, et al. (2009). Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc Nat Acad Sci 106:19268–73.
  • Wang K, Cao P, Wang H, et al. (2016). Chronic administration of Angelica sinensis polysaccharide effectively improves fatty liver and glucose homeostasis in high-fat diet-fed mice. Sci Rep 6:26229.
  • Wu S-J, Don T-M, Lin C-W, Mi F-L. (2014). Delivery of berberine using chitosan/fucoidan-taurine conjugate nanoparticles for treatment of defective intestinal epithelial tight junction barrier. Marine Drugs 12:5677–97.
  • Yan H, Yalagala RS, Yan F. (2015). Fluorescently labelled glycans and their applications. Glycoconj J 32:559–74.
  • Zhang Y, Cheng Y, Wang N, et al. (2014). The action of JAK, SMAD and ERK signal pathways on hepcidin suppression by polysaccharides from Angelica sinensis in rats with iron deficiency anemia. Food Funct 5:1381–8.
  • Zhang Y, Zhou T, Wang H, et al. (2016). Structural characterization and in vitro antitumor activity of an acidic polysaccharide from Angelica sinensis (Oliv.) Diels. Carbohydrate Polymers 147:401–8.
  • Zuo T, Zhang N, Zhang Q, et al. (2016). Transportation of squid ink polysaccharide SIP through intestinal epithelial cells and its utilization in the gastrointestinal tract. J Funct Foods 22:408–16.