2,313
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Effect of finasteride particle size reduction on its pharmacokinetic, tissue distribution and cellular permeation

&
Pages 555-563 | Received 21 Dec 2017, Accepted 11 Feb 2018, Published online: 16 Feb 2018

References

  • Ahmed T. (2016). Preparation of finasteride capsules-loaded drug nanoparticles: formulation, optimization, in vitro, and pharmacokinetic evaluation. Int J Nanomedicine 11:515–27.
  • Ahmed TA, El-Say KM. (2016). Transdermal film-loaded finasteride microplates to enhance drug skin permeation: two-step optimization study. Eur J Pharm Sci 88:246–56.
  • Anutra K, Kumsorn B, Rojanasthien N. (2003). Bioequivalence study of generic finasteride in healthy male volunteers. Chiang Mai Med Bull 42:131–7.
  • Barcelo AC, Olivera MI, Bozzini C, et al. (1999). Androgens and erythropoiesis. Induction of erythropoietin-hypersecretory state and effect of finasteride on erythropoietin secretion. Comp Haematol Int 9:1–6.
  • Blagden N, de Matas M, Gavan PT, York P. (2007). Crystal engineering of active pharmaceutical ingredients to improve solubility and dissolution rates. Adv Drug Deliv Rev 59:617–30.
  • Dokoumetzidis A, Macheras P. (2006). A century of dissolution research: from Noyes and Whitney to the biopharmaceutics classification system. Int J Pharm 321:1–11.
  • Gratton SEA, Ropp PA, Pohlhaus PD, et al. (2008). The effect of particle design on cellular internalization pathways. Proc Natl Acad Sci USA 105:11613–8.
  • Hao J, Gao Y, Zhao J, et al. (2015). Preparation and optimization of resveratrol nanosuspensions by antisolvent precipitation using box-behnken design. AAPS PharmSciTech 16:118–28.
  • Haque A, Ishii Y, Akasaka Y, et al. (2017). Administration of colistin sulfate in endotoxic model at slow and sustained fashion may reverse shock without causing nephrotoxicity in its optimal concentration. J Glob Antimicrob Resist 11:40–4.
  • Ishii Y, Mukoyama H, Ohtawa M. (1994). In vitro biotransformation of finasteride in rat hepatic microsomes. Isolation and characterization of metabolites. Drug Metab Dispos 22:79–84.
  • Jinno J, Kamada N, Miyake M, et al. (2006). Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs. J Control Release 111:56–64.
  • Junghanns JUAH, Müller RH. (2008). Nanocrystal technology, drug delivery and clinical applications. Int J Nanomedicine 3:295–309.
  • Kolasa-Wolosiuk A, Misiakiewicz-Has K, Baranowska-Bosiacka I, et al. (2015). Androgen levels and apoptosis in the testis during postnatal development of finasteride-treated male rat offspring. Folia Histochem Cytobiol 53:236–48.
  • Lam KH, Schakenraad JM, Esselbrugge H, et al. (1993). The effect of phagocytosis of poly (l‐lactic acid) fragments on cellular morphology and viability. J Biomed Mater Res Part A 27:1569–77.
  • Mathur S, Picard F, Dossou U, et al. (2004). Evaluation of cell permeation of a potent 5α-reductase inhibitor using MALDI-TOF MS. J Enzyme Inhib Med Chem 19:425–9.
  • Maureen Dale M, Rang H. Rang and Dale’s pharmacology. 7th ed. New York: Elsevier/Churchill Livingstone; 2012.
  • Merckle P, Kovar K. (1998). Assay of effervescent tablets by near-infrared spectroscopy in transmittance and reflectance mode: acetylsalicylic acid in mono and combination formulations. J Pharm Biomed Anal 17:365–74.
  • Merkely B, Dósa E, Neuwelt EA, et al. (2017). Dose escalation study of intravenous and intra-arterial N-acetylcysteine for the prevention of oto-and nephrotoxicity of cisplatin with a contrast-induced nephropathy model in patients with renal insufficiency. Fluids Barriers CNS. BioMed Central 14:26.
  • Monti D, Tampucci S, Burgalassi S, et al. (2014). Topical formulations containing finasteride. Part I: in vitro permeation/penetration study and in vivo pharmacokinetics in hairless rat. J Pharm Sci 103:2307–14.
  • Pande VV, Abhale VN. (2013). Nanocrystal technology: a particle engineering formulation strategy for the poorly water soluble drugs. Int J Pharm 453:126–41.
  • Prahalada SR, Keenan KP, Hertzog PR, et al. (1994). Qualitative and quantitative evaluation of prostatic histomorphology in rats following chronic treatment with finasteride, a 5-alpha reductase inhibitor. Urology 43:680–5.
  • Rodrigues S, Cordeiro C, Seijo B, et al. (2015). Hybrid nanosystems based on natural polymers as protein carriers for respiratory delivery: stability and toxicological evaluation. Carbohydr Polym 123:369–80.
  • Rogers TL, Johnston KP, Williams RO. (2001). Solution-based particle formation of pharmaceutical powders by supercritical or compressed fluid CO2 and cryogenic spray-freezing technologies. Drug Dev Ind Pharm 27:1003–15.
  • Siddiqui MR, AlOthman ZA, Rahman N. (2017). Analytical techniques in pharmaceutical analysis: a review. Arab J Chem 10:S1409–S21.
  • Soni KK, Shin YS, Choi BR, Karna KK, Kim HK, Lee SW, etet al. (2017). Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway. Drug Des Devel Ther 11:2969.
  • Steiner JF. (1996). Clinical pharmacokinetics and pharmacodynamics of finasteride. Clin Pharmacokinet 30:16–27.
  • Sun J, Wang F, Sui Y, et al. (2012). Effect of particle size on solubility, dissolution rate, and oral bioavailability: evaluation using coenzyme Q10 as naked nanocrystals. Int J Nanomedicine 7:5733–44.
  • Sutradhar KB, Khatun S, Luna IP. (2013). Increasing possibilities of nanosuspension. J Nanotechnol 2013:1–12.
  • Tampucci S, Burgalassi S, Chetoni P, et al. (2014). Topical formulations containing finasteride. Part II: determination of finasteride penetration into hair follicles using the differential stripping technique. J Pharm Sci 103:2323–9.
  • Tian G, Stuart JD, Moss ML, et al. (1994). 17 Beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androstan-1-en-3-one is an active site-directed slow time-dependent inhibitor of human steroid 5 alpha-reductase 1. Biochemistry 33:2291–6.
  • Van Eerdenbrugh B, Van den Mooter G, Augustijns P. (2008). Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products. Int J Pharm 364:64–75.
  • Wang H, Li Q, Reyes S, et al. (2013). Formulation and particle size reduction improve bioavailability of poorly water-soluble compounds with antimalarial activity. Malar Res Treat 2013:1–10.
  • Wang Y, Zheng Y, Zhang L, et al. (2013). Stability of nanosuspensions in drug delivery. J Control Release 172:1126–41.
  • Willmann S, Thelen K, Becker C, et al. (2010). Mechanism-based prediction of particle size-dependent dissolution and absorption: cilostazol pharmacokinetics in dogs. Eur J Pharm Biopharm 76:83–94.
  • Wurzel R, Ray P, Major-Walker K, et al. (2007). The effect of dutasteride on intraprostatic dihydrotestosterone concentrations in men with benign prostatic hyperplasia. Prostate Cancer Prostatic Dis 10:149–54.
  • Zhang L, Gu FX, Chan JM, et al. (2008). Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther 83:761–9.
  • Zhang M, Wu W, Zhang C, et al. (2012). Effects of oral finasteride on erectile function in a rat model. J Sex Med 9:1328–36.