Microchannel-embedded implantable device with fibrosis suppression for prolonged controlled drug delivery

References

• Araújo J, Gonzalez E, Egea MA, et al. (2009). Nanomedicines for ocular NSAIDs: safety on drug delivery. Nanomedicine 5:394–401.
   PubMed Web of Science ®Google Scholar
• Asrory VDO, Sitompul R, Artini W, et al. (2020). The inflammatory and foreign body reaction of polymethyl methacrylate glaucoma drainage device in the rabbit eye. Transl Vis Sci Technol 9:20.
   PubMed Web of Science ®Google Scholar
• Bank RA. (2019). Limiting biomaterial fibrosis. Nat Mater 18:781.
   PubMed Web of Science ®Google Scholar
• Carnicer-Lombarte A, Chen ST, Malliaras GG, et al. (2012). Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics. Front Bioeng 9:622524.
   Web of Science ®Google Scholar
• Choi JS, Huh BK, Lee SJ, et al. (2020). Tranilast-loaded tubular scaffold and surgical suture for suppression of stenosis after tracheal prosthesis transplantation. J Ind Eng Chem 82:81–8.
   Web of Science ®Google Scholar
• Chun NY, Kim SN, Choi YS, et al. (2020). PCN-223 as a drug carrier for potential treatment of colorectal cancer. J Ind Eng Chem 84:290–6.
   Web of Science ®Google Scholar
• Cirri M, Maestrelli F, Corti G, et al. (2007). Fast-dissolving tablets of glyburide based on ternary solid dispersions with PEG 6000 and surfactants. Drug Deliv 14:247–55.
   PubMed Web of Science ®Google Scholar
• Diegelmann RF, Evans MC. (2004). Wound healing: an overview of acute, fibrotic and delayed healing. Front Biosci 9:283–9.
   PubMed Web of Science ®Google Scholar
• Elman NM, Duc HLH, Cima MJ. (2009). An implantable MEMS drug delivery device for rapid delivery in ambulatory emergency care. Biomed Microdevices 11:625–31.
   PubMed Web of Science ®Google Scholar
• Farra R, Sheppard NF, McCabe L, et al. (2012). First-in-human testing of a wirelessly controlled drug delivery microchip. Sci Transl Med 4:122ra21.
   PubMed Web of Science ®Google Scholar
• Gardner P. (2006). Microfabricated nanochannel implantable drug delivery devices: trends, limitations and possibilities. Expert Opin Drug Deliv 3:479–87.
   PubMedGoogle Scholar
• Gautam R, Singh RD, Sharma VP, et al. (2012). Biocompatibility of polymethylmethacrylate resins used in dentistry. J Biomed Mater Res B Appl Biomater 100:1444–50.
   PubMed Web of Science ®Google Scholar
• Hameed HA, Khan S, Shahid M, et al. (2020). Engineering of naproxen loaded polymer hybrid enteric microspheres for modified release tablets: development, characterization, in silico modelling and in vivo evaluation. Drug Des Devel Ther 14:27–41.
   PubMed Web of Science ®Google Scholar
• Heo MY, Piao ZZ, Kim TW, et al. (2005). Effect of solubilizing and microemulsifying excipients in polyethylene glycol 6000 solid dispersion on enhanced dissolution and bioavailability of ketoconazole. Arch Pharm Res 28:604–11.
   PubMed Web of Science ®Google Scholar
• Hilt JZ, Peppas NA. (2005). Microfabricated drug delivery devices. Int J Pharm 306:15–23.
   PubMed Web of Science ®Google Scholar
• Holmes D, Fitzgerald P, Goldberg S, et al. (2000). The PRESTO (Prevention of restenosis with tranilast and its outcomes) protocol: a double-blind, placebo-controlled trial. Am Heart J 139:23–31.
   PubMed Web of Science ®Google Scholar
• Jeong H, Rho J, Shin JY, et al. (2018). Mechanical properties and cytotoxicity of PLA/PCL films. Biomed Eng Lett 8:267–72.
   PubMed Web of Science ®Google Scholar
• Ji HB, Kim SN, Lee SH, et al. (2020). Soft implantable device with drug-diffusion channels for the controlled release of diclofenac. J Control Release 318:176–84.
   PubMed Web of Science ®Google Scholar
• Kim BH, Huh BK, Lee WS, et al. (2019). Silicone implant coated with tranilast-loaded polymer in a pattern for fibrosis suppression. Polymers 11:223.
   PubMed Web of Science ®Google Scholar
• Kincl M, Vrečer F, Veber M. (2004). Characterization of factors affecting the release of low-solubility drug from prolonged release tablets. Anal Chim Acta 502:107–13.
   Web of Science ®Google Scholar
• Lee KJ, Yang SY, Ryu W. (2012). Controlled release of bupivacaine HCl through microchannels of biodegradable drug delivery device. Biomed Microdevices 14:583–93.
   PubMed Web of Science ®Google Scholar
• Lee SH, Kim BH, Park CG, et al. (2018). Implantable small device enabled with magnetic actuation for on-demand and pulsatile drug delivery. J Control Release 286:224–30.
   PubMed Web of Science ®Google Scholar
• Lee SH, Park M, Park CG, et al. (2012). Microchip for sustained drug delivery by diffusion through microchannels. AAPS PharmSciTech 13:211–7.
   PubMed Web of Science ®Google Scholar
• Lee SH, Park M, Park CG, et al. (2014). Implantable micro-chip for controlled delivery of diclofenac sodium. J Control Release 196:52–9.
   PubMed Web of Science ®Google Scholar
• Marcus J, Alyssa P, Stephanie B, et al. (2016). Investigation of diffusion characteristics through microfluidic channels for passive drug delivery applications. J Drug Deliv 2016:7913616.
   PubMedGoogle Scholar
• Martin C, De Baerdemaeker A, Poelaert J, et al. (2016). Controlled-release of opioids for improved pain management. Mater Today 19:491–502.
   Web of Science ®Google Scholar
• Martin S, Macarena S, Charlotte S, et al. (2012). Biocompatibility and antifibrotic effect of UV-cross-linked hyaluronate as a release-system for tranilast after trabeculectomy in a rabbit model – a pilot study. Curr Eye Res 37:463–70.
   PubMed Web of Science ®Google Scholar
• Meng E, Hoang T. (2012). Micro- and nano-fabricated implantable drug-delivery systems. Ther Deliv 3:1457–67.
   PubMedGoogle Scholar
• Meng X, Nikolic-Paterson DJ, Lan HY. (2016). TGF-β: the master regulator of fibrosis. Nat Rev Nephrol 12:325–38.
   PubMed Web of Science ®Google Scholar
• Nam SY, Ji HB, Shin BH, et al. (2021). Silicone breast implant coated with triamcinolone inhibited breast-implant-induced fibrosis in a porcine model. Materials 14:3917.
   PubMed Web of Science ®Google Scholar
• Odom DM, Mladsi DM, Saag KG, et al. (2014). Relationship between diclofenac dose and risk of gastrointestinal and cardiovascular events: meta-regression based on two systematic literature reviews. Clin Ther 36:906–17.
   PubMed Web of Science ®Google Scholar
• Park S, Park M, Kim BH, et al. (2015). Acute suppression of TGF-β with local, sustained release of tranilast against the formation of fibrous capsules around silicone implants. J Control Release 200:125–37.
   PubMed Web of Science ®Google Scholar
• Paz E, Ballesteros Y, Abenojar J, et al. (2021). Advanced G-MPS-PMMA bone cements: influence of graphene silanisation on fatigue performance, thermal properties and biocompatibility. Nanomaterials 11:139.
   Web of Science ®Google Scholar
• Pons-Faudoa FP, Ballerini A, Sakamoto J, et al. (2019). Advanced implantable drug delivery technologies: transforming the clinical landscape of therapeutics for chronic diseases. Biomed Microdevices 21:1–22.
   Web of Science ®Google Scholar
• Robotti F, Sterner I, Bottan S, et al. (2020). Microengineered biosynthesized cellulose as anti-fibrotic in vivo protection for cardiac implantable electronic devices. Biomaterials 229:119583.
   PubMed Web of Science ®Google Scholar
• Sanjay ST, Zhou W, Dou M, et al. (2018). Recent advances of controlled drug delivery using microfluidic platforms. Adv Drug Deliv Rev 128:3–28.
   PubMed Web of Science ®Google Scholar
• Singh M, Gersh BJ, McClelland RL, et al. (2004). Clinical and angiographic predictors of restenosis after percutaneous coronary intervention. Circulation 109:2727–31.
   PubMed Web of Science ®Google Scholar
• Stevenson CL, Santini JT, Jr, Langer R. (2012). Reservoir-based drug delivery systems utilizing microtechnology. Adv Drug Deliv Rev 64:1590–602.
   PubMed Web of Science ®Google Scholar
• Sutradhar KB, Sumi CD. (2016). Implantable microchip: the futuristic controlled drug delivery system. Drug Deliv 23:1–11.
   PubMed Web of Science ®Google Scholar
• Ward WK. (2008). A review of the foreign-body response to subcutaneously-implanted devices: the role of macrophages and cytokines in biofouling and fibrosis. J Diabetes Sci Technol 2:768–77.
   PubMedGoogle Scholar
• Yang D, Lee JS, Choi CK, et al. (2018a). Microchannel system for rate-controlled, sequential, and pH-responsive drug delivery. Acta Biomater 68:249–60.
   PubMed Web of Science ®Google Scholar
• Yang W, Sabi-Mouka EMB, Wang L, et al. (2018b). Determination of tranilast in bio-samples by LC–MS/MS: application to a pharmacokinetic and brain tissue distribution study in rats. J Pharm Biomed Anal 147:479–84.
   PubMed Web of Science ®Google Scholar