Preparation of uniform-sized GeXIVA[1,2]-loaded PLGA microspheres as long-effective release system with high encapsulation efficiency

References

• Alsharari SD, Toma W, Mahmood HM, et al. (2020). The α9α10 nicotinic acetylcholine receptors antagonist α-conotoxin RgIA reverses colitis signs in murine dextran sodium sulfate model. Eur J Pharmacol 883:173320.
   PubMed Web of Science ®Google Scholar
• Angst MS, Clark JD. (2006). Opioid-induced hyperalgesia: a qualitative systematic review. Anesthesiology 104:570–87.
   PubMed Web of Science ®Google Scholar
• Chou R, Turner JA, Devine EB, et al. (2015). The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention Workshop. Ann Intern Med 162:276–86.
   PubMed Web of Science ®Google Scholar
• Coll-Satue C, Jansman MMT, Thulstrup PW, et al. (2021). Optimization of hemoglobin encapsulation within PLGA nanoparticles and their investigation as potential oxygen carriers. Pharmaceutics 13:1958.
   PubMed Web of Science ®Google Scholar
• Devereaux AL, Mercer SL, Cunningham CW. (2018). DARK classics in chemical neuroscience: morphine. ACS Chem Neurosci 9:2395–407.
   PubMed Web of Science ®Google Scholar
• Diwan M, Park TG. (2001). Pegylation enhances protein stability during encapsulation in PLGA microspheres. J Control Release 73:233–44.
   PubMed Web of Science ®Google Scholar
• Duncan G, Jess TJ, Mohamed F, et al. (2005). The influence of protein solubilisation, conformation and size on the burst release from poly(lactide-co-glycolide) microspheres. J Control Release 110:34–48.
   PubMed Web of Science ®Google Scholar
• El-Maghawry E, Tadros MI, Elkheshen SA, et al. (2020). Eudragit(®)-S100 coated PLGA nanoparticles for colon targeting of etoricoxib: optimization and pharmacokinetic assessments in healthy human volunteers. IJN Volume 15:3965–80.
   Web of Science ®Google Scholar
• Fu X, He X, Xing H. (2012). Preparation of single-hole silica hollow microspheres by precipitation-phase separation method. Colloid Surf A Physicochem Eng Aspect 396:283–91.
   Web of Science ®Google Scholar
• Giunchedi P, Conti B, Genta I, et al. (2001). Emulsion spray-drying for the preparation of albumin-loaded PLGA microspheres. Drug Dev Ind Pharm 27:745–50.
   PubMed Web of Science ®Google Scholar
• Guo Y, Yang Y, He L, et al. (2017). Injectable sustained-release depots of PLGA microspheres for insoluble drugs prepared by hot-melt extrusion. Pharm Res 34:2211–22.
   PubMed Web of Science ®Google Scholar
• Hua Y, Su Y, Zhang H, et al. (2021). Poly(lactic-co-glycolic acid) microsphere production based on quality by design: a review. Drug Deliv 28:1342–55.
   PubMed Web of Science ®Google Scholar
• Jain RA, Rhodes CT, Railkar AM, et al. (2000). Comparison of various injectable protein-loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices: in-situ-formed implant versus in-situ-formed microspheres versus isolated microspheres. Pharm Dev Technol 5:201–7.
   PubMed Web of Science ®Google Scholar
• Jeyanthi R, Mehta RC, Thanoo BC, et al. (1997). Effect of processing parameters on the properties of peptide-containing PLGA microspheres. J Microencapsul 14:163–74.
   PubMed Web of Science ®Google Scholar
• Khan GM, Chen SR, Pan HL. (2002). Role of primary afferent nerves in allodynia caused by diabetic neuropathy in rats. Neuroscience 114:291–9.
   PubMed Web of Science ®Google Scholar
• Klose D, Siepmann F, Elkharraz K, et al. (2006). How porosity and size affect the drug release mechanisms from PLGA-based microparticles. Int J Pharm 314:198–206.
   PubMed Web of Science ®Google Scholar
• Latha S, Selvamani P, Suganya G, et al. (2021). Preparation and in-vitro evaluation of pantoprazole sodium magnetic microspheres by emulsion solvent evaporation method. BioNanoSci 11:643–7.
   Web of Science ®Google Scholar
• Mcginity JW, O’donnell PB. (1997). Preparation of microspheres by the solvent evaporation technique. Adv Drug Deliv Rev 28:25–42.
   PubMed Web of Science ®Google Scholar
• Park H, Ha DH, Ha ES, et al. (2019). Effect of stabilizers on encapsulation efficiency and release behavior of exenatide-loaded PLGA microsphere prepared by the W/O/W solvent evaporation method. Pharmaceutics 11:627.
   PubMed Web of Science ®Google Scholar
• Qi F, Wu J, Fan Q, et al. (2013). Preparation of uniform-sized exenatide-loaded PLGA microspheres as long-effective release system with high encapsulation efficiency and bio-stability. Colloids Surf B Biointerfaces 112:492–8.
   PubMed Web of Science ®Google Scholar
• Shive MS, Anderson JM. (1997). Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev 28:5–24.
   PubMed Web of Science ®Google Scholar
• Uchida T, Yoshida K, Goto S. (1996). Preparation and characterization of polylactic acid microspheres containing water-soluble dyes using a novel w/o/w emulsion solvent evaporation method. J Microencapsul 13:219–28.
   PubMed Web of Science ®Google Scholar
• Van Gunsteren WF, Daura X, Hansen N, et al. (2018). Validation of molecular simulation: an overview of issues. Angew Chem Int Ed Engl 57:884–902.
   PubMed Web of Science ®Google Scholar
• Vincler M, Mcintosh JM. (2007). Targeting the alpha9alpha10 nicotinic acetylcholine receptor to treat severe pain. Expert Opin Ther Targets 11:891–7.
   PubMed Web of Science ®Google Scholar
• Wang H, Li X, Zhangsun D, et al. (2019). The α9α10 nicotinic acetylcholine receptor antagonist αO-conotoxin GeXIVA[1,2] alleviates and reverses chemotherapy-induced neuropathic pain. Mar Drugs 17:265.
   Web of Science ®Google Scholar
• Wang LY, Ma GH, Su ZG. (2005). Preparation of uniform sized chitosan microspheres by membrane emulsification technique and application as a carrier of protein drug. J Control Release 106:62–75.
   PubMed Web of Science ®Google Scholar
• Wang Y, Qiu Y, Jinghong MA, et al. (2018). Preparation and characterization of poly(N-isopropylacryamide-co-methacrylic acid) hydrogel microspheres by microfluidic method. J Donghua Univ 44:93–99.
   Google Scholar
• Wang Y, Zhang F, Xu S, et al. (2008). Preparation of layered double hydroxide microspheres by spray drying. Ind Eng Chem Res 47:5746–50.
   Web of Science ®Google Scholar
• Xu P, Kaas Q, Wu Y, et al. (2020). Structure and activity studies of disulfide-deficient analogues of αO-conotoxin GeXIVA. J Med Chem 63:1564–75.
   PubMed Web of Science ®Google Scholar
• Yang YY, Chia HH, Chung TS. (2000). Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. J Control Release 69:81–96.
   PubMed Web of Science ®Google Scholar
• Yousuf A, Wu X, Bony AR, et al. (2022). ɑO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV 2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activation. J Neurochem 160:154–71.
   PubMed Web of Science ®Google Scholar
• Yu S, Wu Y, Xu P, et al. (2018). Effects of serum, enzyme, thiol, and forced degradation on the stabilities of αO-Conotoxin GeXIVA[1,2] and GeXIVA [1,4]. Chem Biol Drug Des 91:1030–41.
   PubMed Web of Science ®Google Scholar
• Zhu KJ, Jiang HL, Du XY, et al. (2001). Preparation and characterization of hCG-loaded polylactide or poly(lactide-co-glycolide) microspheres using a modified water-in-oil-in-water (w/o/w) emulsion solvent evaporation technique. J Microencapsul 18:247–60.
   PubMed Web of Science ®Google Scholar