Enhanced transdermal insulin basal release from silk fibroin (SF) hydrogels via iontophoresis

References

• Alexander A, Dwivedi S, Giri TK, et al. (2012). Approaches for breaking the barriers of drug permeation through transdermal drug delivery. J Control Release 164:26–40.
   PubMed Web of Science ®Google Scholar
• Alkilani AZ, McCrudden MTC, Donnelly RF. (2015). Transdermal drug delivery: innovative pharmaceutical developments based on disruption of the barrier properties of the stratum corneum. Pharmaceutics 7:438–70.
   PubMed Web of Science ®Google Scholar
• Bashyal S, Shin CY, Hyun SM, et al. (2020). Preparation, characterization, and in vivo pharmacokinetic evaluation of polyvinyl alcohol and polyvinyl pyrrolidone blended hydrogels for transdermal delivery of donepezil HCl. Pharmaceutics 12:270.
   PubMed Web of Science ®Google Scholar
• Chaudhry ZW, Gannon MC, Nuttall FQ. (2006). Stability of body weight in type 2 diabetes. Diabete Care 29:493–7.
   PubMed Web of Science ®Google Scholar
• Chen H, Zhu H, Zheng J, et al. (2009). Iontophoresis-driven penetration of nanovesicles through microneedle-induced skin microchannels for enhancing transdermal delivery of insulin. J Control Release 139:63–72.
   PubMed Web of Science ®Google Scholar
• Chowdhury AM, Khan RI, NirzhorJabin SSR, et al. (2017). A novel approach in adjustment of total daily insulin dosage for type 2 diabetes patients using a fuzzy logic based system. J Innov Pharm Biol Sci 4:65–72.
   Google Scholar
• Chwedoruk W, Malka I, Bozycki L, et al. (2014). On the heat stability of amyloid-based biological activity: insights from thermal degradation of insulin fibrils. PLoS ONE 9:e86320.
   Web of Science ®Google Scholar
• Correa EE, Lopera DOG, Restrepo SG, et al. (2020). Effective sericin fibroin separation from Bombyx mori silkworms fibers and low cost salt removal from fibroin solution. Rev Fac Ing. Univ Antioquia 94:97–101.
   Google Scholar
• Darge HF, Andrgie AT, Hanurry EY, et al. (2019). Localized controlled release of bevacizumab and doxorubicin by thermosensitive hydrogel for normalization of tumor vasculature and to enhance the efficacy of chemotherapy. Int J Pharm 572:118799.
   PubMed Web of Science ®Google Scholar
• Dwivedi N, Arunagirinathan MA, Sharma S, Bellare J. (2010). Silica-coated liposomes for insulin delivery. J Nanomater 2010:652048.
   Web of Science ®Google Scholar
• Higuchi T. (1961). Rate of release of medicaments from ointment bases containing drugs in suspension. J Pharm Sci 50:874–5.
   PubMed Web of Science ®Google Scholar
• Hu Y, Zhang Q, You R, et al. (2012). The relationship between secondary structure. Adv Mater Sci Eng 2012:1–5.
   Web of Science ®Google Scholar
• Huang D, Sun M, Bu Y, et al. (2019). Microcapsule- embedded hydrogel patches for ultrasound responsive and enhanced transdermal delivery of diclofenac sodium. J Mater Chem B 7:2330–7.
   PubMed Web of Science ®Google Scholar
• Johari N, Moroni L, Samadikuchaksaraei A. (2020). Tuning the conformation and mechanical properties of silk fibroin hydrogels. Eur Polym J 134:109842.
   Web of Science ®Google Scholar
• Kapoor S, Kundu SC. (2015). Silk protein-based hydrogels: Promising advanced materials for biomedical applications. Acta Biomater 31:17–32.
   PubMed Web of Science ®Google Scholar
• Kim MH, Park WH. (2016). Chemically cross-linked silk fibroin hydrogel with enhanced elastic properties, biodegradability, and biocompatibility. Int J Nanomed 11:2978.
   Web of Science ®Google Scholar
• Knopp JL, Pearson LH, Chase JG. (2019). Insulin units and conversion factors: a story of truth, boots, and faster half-truths. J Diabetes Sci Technol 13:597–600.
   PubMedGoogle Scholar
• Korsmeyer RW, Gurny R, Doelker E, et al. (1983). Mechanisms of solute release from porous hydrophilic polymers. Int J Pharm 15:25–35.
   Web of Science ®Google Scholar
• Kuang D, Jiang F, Wu F, et al. (2019). Highly elastomeric photocurable silk hydrogels. Int J Biol Macromol 134:838–45.
   PubMed Web of Science ®Google Scholar
• Kuang D, Wu F, Yin Z, et al. (2018). Silk fibroin/polyvinyl pyrrolidone interpenetrating polymer network hydrogels. Polymers 10:153.
   PubMed Web of Science ®Google Scholar
• Lammel A, Hu X, Park SH, et al. (2010). Controlling silk fibroin particle features for drug delivery. Biomaterials 31:4583–91.
   PubMed Web of Science ®Google Scholar
• Langer RS, Peppas NA. (1981). Present and future applications of biomaterials in controlled drug release systems. Biomaterials 2:201–14.
   PubMed Web of Science ®Google Scholar
• Li J, Mooney DJ. (2016). Designing hydrogels for controlled drug delivery. Nat Rev Mater 1:1–37.
   Web of Science ®Google Scholar
• Lim KS. (2015). Silk hydrogels for tissue engineering. Winter Solstic 21:1–7.
   Google Scholar
• Lougheed WD, Fischer U, Perlman K, et al. (1981). A physiological solvent for crystalline insulin. Diabetologia 20:51–3.
   PubMed Web of Science ®Google Scholar
• Lougheed WD, Woulfe-Flanagan H, Clement JR, Albisser AM. (1980). Insulin aggregation in artificial delivery systems. Diabetologia 19:1–19.
   PubMed Web of Science ®Google Scholar
• Magos M, Tapia J, López M, et al. (2020). Cytotoxicity and UV light absorption in biopolymeric membranes from native vegetation of mexico. Appl Sci 10:4995.
   Google Scholar
• Maji P, Gandhi A, J S, Maji N. (2013). Preparation and characterization of maleic anhydride cross-linked chitosan-polyvinyl alcohol hydrogel matrix transdermal patch. J PharmaSciTech 2:62–7.
   Google Scholar
• Mallawarachchi S, Mahadevan A, Gejji V, Fernando S. (2019). Mechanics of controlled release of insulin entrapped in polyacrylic acid gels via variable electrical stimuli. Drug Deliv Transl Res 9:783–94.
   PubMed Web of Science ®Google Scholar
• Manno M, Craparo EF, Martorana V, et al. (2006). Kinetics of insulin aggregation: disentanglement of amyloid fibrillation from large-size cluster formation. Biophys J 90:4585–91.
   PubMed Web of Science ®Google Scholar
• Mansoor S, Kondiah PPD, Choonara YE, Pillay V. (2019). Polymer-based nanoparticle strategies. Polymers 11:1380.
   PubMed Web of Science ®Google Scholar
• Mavondo GAA, Tagumirwa MC. (2016). Asiatic acid-pectin hydrogel matrix patch transdermal delivery system influences parasitaemia suppression and inflammation reduction in P. berghei murine malaria infected sprague–dawley rats. Asian Pac J Trop Med 9:1172–1180.
   PubMed Web of Science ®Google Scholar
• Mongkolkitikul S, Paradee N, Sirivat A. (2017). Electrically controlled release of ibuprofen from conductive poly(3-methoxydiphenylamine)/crosslinked pectin hydrogel. Eur J Pharm Sci 112:20–7.
   PubMed Web of Science ®Google Scholar
• Murthy SN. (2012). Transdermal drug delivery: approaches and significance. RRTD 1:1–2.
   Google Scholar
• Nadendla K, Friedman SH. (2017). Light control of protein solubility through isoelectric point modulation. J Am Chem Soc 49:17861–9.
   Web of Science ®Google Scholar
• Narita C, Okahisa Y, Wataoka I, Yamada K. (2021). Characterization of ground silk fibroin through comparison of nanofibroin and higher order structures. ACS Omega 5:22786–−92.
   Web of Science ®Google Scholar
• Niswender KD. (2011). Basal insulin: physiology, pharmacology, and clinical implications. Postgrad Med 123:17–26.
   PubMed Web of Science ®Google Scholar
• Oktay S, Alemdar N. (2018). Electrically controlled release of 5-fluorouracil from conductive gelatin methacryloyl-based hydrogels. J Appl Polym Sci 136:46914.
   Web of Science ®Google Scholar
• Paradee N, Thanokiang J, Sirivat A. (2021). Conductive poly(2-ethylaniline) dextran-based hydrogels for electrically controlled diclofenac release. Mater Sci Eng C 118:111346.
   PubMed Web of Science ®Google Scholar
• Park HJ, Lee JS, Lee OJ, Sheikh FA, et al. (2014). Fabrication of microporous three-dimensional scaffolds from silk fibroin for tissue engineering. Macromol Res 22:592–9.
   Web of Science ®Google Scholar
• Patarroyo JL, Florez-Rojas JS, Pradilla D, et al. (2020). Formulation and characterization of gelatin-based hydrogels for the encapsulation of kluyveromyces lactis—applications in packed-bed reactors and probiotics delivery in humans. Polymers 12:1287.
   PubMed Web of Science ®Google Scholar
• Peppas NA, Merrill EW. (1977). Crosslinked poly(vinyl alcohol) hydrogels as swollen elastic networks. J Appl Polym Sci 21:1763–70.
   Web of Science ®Google Scholar
• Peppas NA, Wright SL. (1996). Solute diffusion in poly(vinyl alcohol)/poly(acrylic acid) interpenetrating networks. Macromolecules 29:8798–804.
   Web of Science ®Google Scholar
• Pillai O, Kumar N, Dey CS, et al. (2003). Transdermal iontophoresis of insulin. Part 1: A study on the issues associated with the use of platinum electrodes on rat skin. J Pharm Pharmacol 55:1505–1513.
   PubMed Web of Science ®Google Scholar
• Pillai O, Nair V, Panchagnula R. (2004). Transdermal iontophoresis of insulin: IV. Influence of chemical enhancers. Int J Pharm 269:109–20.
   PubMed Web of Science ®Google Scholar
• Pillai O, Panchagnula R. (2004). Transdermal iontophoresis of insulin: VI. Influence of pretreatment with fatty acids on permeation across rat skin. Skin Pharmacol Physiol 17:289–97.
   PubMed Web of Science ®Google Scholar
• Quicenoa NJ. Lópezb CA, Osorioc AR (2017). Structural and thermal properties of silk fibroin films obtained from cocoon and waste silk fibers as raw materials. Procedia Eng 200:384–8.
   Google Scholar
• Radu IC, Biru IE, Damian CM, et al. (2019). Grafting versus crosslinking of silk fibroin-g-PNIPAM via tyrosine-NIPAM bridges. Molecules 24:4096.
   PubMed Web of Science ®Google Scholar
• Ruangmak K, Paredee N, Niamlang S, et al. (2021). Electrically controlled transdermal delivery of naproxen and indomethacin from porous cis-1,4-polyisoprene matrix. J Biomed Mater Res Part B: Appl Biomater 110:1–11.
   Web of Science ®Google Scholar
• Schacht EH. (2004). Polymer chemistry and hydrogel systems. J Phys: Conf Ser 3:22–8.
   Google Scholar
• Sen M, Uzun C, Guven O. (2000). Controlled release of terbinafine hydrochloride from pH sensitive poly(acrylamide/maleic acid) hydrogels. Int J Pharm 203:149–57.
   PubMed Web of Science ®Google Scholar
• Shah RB, Patel M, Maahs DM, Shah VN. (2016). Insulin delivery methods: past, present and future. Int J Pharma Investig 6:1–9.
   PubMed Web of Science ®Google Scholar
• Srinivasan V, Higuchi WI, Sims SM, et al. (1987). Trandermal iontophoretic drug delivery: mechanistic analysis and application to polypeptide delivery. J Pharm Sci 78:370–5.
   Web of Science ®Google Scholar
• Szunerits S, Boukherroub R. (2018). Heat: A highly efficient skin enhancer for transdermal drug delivery. Front Bioeng Biotechnol 6:1–13.
   PubMed Web of Science ®Google Scholar
• Tari K, Khamoushian S, Madrakian T, et al. (2021). Controlled transdermal iontophoresis of insulin from water-soluble polypyrrole nanoparticles: an in vitro study. IJMS 22:12479.
   Web of Science ®Google Scholar
• Tokumoto S, Higo N, Sugibayashi K. (2006). Effect of electroporation and pH on the iontophoretic transdermal delivery of human insulin. Int J Pharm 326:13–9.
   PubMed Web of Science ®Google Scholar
• Varkey A, Venugopal E, Sugumaran P, et al. (2015). Impact of silk fibroin-based scaffold structures on human osteoblast MG63 cell attachment and proliferation. Int J Nanomed 10:43–51.
   PubMedGoogle Scholar
• Whittaker JL, Choudhury NR, Dutta NK, Zannettino A. (2014). Facile and rapid ruthenium mediated photocrosslinking of Bombyx mori silk fibroin. J Mater Chem B 2:6259–70.
   PubMed Web of Science ®Google Scholar
• Wu N, Yu H, Sun M, et al. (2019). Investigation on the structure and mechanical properties of highly tunable elastomeric silk fibroin hydrogels cross-linked by γ‑ray radiation. ACS Appl Bio Mater 3:721–34.
   Google Scholar
• Yang J, Li Y, Ye R, et al. (2020). Smartphone-powered iontophoresis-microneedle array patch for controlled transdermal delivery. Microsyst Nanoeng 6:112.
   PubMed Web of Science ®Google Scholar
• Ye S, Wang C, Liu X, et al. (2006). New loading process and release properties of insulin from polysaccharide microcapsules fabricated through layer-by-layer assembly. J Control Release 112:79–87.
   PubMed Web of Science ®Google Scholar
• Zhang H, Li LL, Dai F, et al. (2012). Preparation and characterization of silk fibroin as a biomaterial with potential for drug delivery. J Transl Med 10:117.
   PubMed Web of Science ®Google Scholar
• Zhang L, Jiang H, Zhu W, et al. (2008). Improving the stability of insulin in solutions containing intestinal proteases in vitro. Int J Mol Sci 9:2376–87.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Yu J, Kahkoska AR, et al. (2019). Advances in transdermal insulin delivery. Adv Drug Deliv Rev 139:51–70.
   PubMed Web of Science ®Google Scholar
• Zhang Z, Xin P, Ou Q, et al. (2018). Poly(ester amide)-based hybrid hydrogels for efficient transdermal insulin delivery. J Mater Chem B 6:6723–30.
   PubMed Web of Science ®Google Scholar
• Zheng H, Duan B, Xie Z, et al. (2020). Inventing a facile method to construct Bombyx mori (B. mori) silk fibroin nanocapsules for drug delivery. RSC Adv 10:28408–14.
   PubMed Web of Science ®Google Scholar