Separation and Determination of Water Soluble Active Components in Salvia miltiorrhiza Bunge and Its Pharmaceutical Preparations by Capillary Zone Electrophoresis with Diode Array Detection

References

• Li , L. N. 1998 . Biologically active components from traditional Chinese medicines . Pure Appl. Chem. , 70 ( 3 ) : 547 – 554 .
   Web of Science ®Google Scholar
• Bent , S. H. and Ko , R. 2004 . Commonly used herbal medicines in the United States: a review . Am. J. Med. , 116 ( 7 ) : 478 – 485 .
   PubMed Web of Science ®Google Scholar
• 2005 . Pharmacopoeia of Peoples Republic of China 52 – 53 . Beijing : Chemical Industry Press . National Commission of Chinese Pharmacopoeia
   Google Scholar
• Liu , J. , Shen , H. M. and Ong , C. N. 2000 . Salvia miltiorrhiza inhibits cell growth and induces apoptosis in human hepatoma HepG2 cells . Cancer Letts. , 153 ( 1 ) : 85 – 93 .
   PubMed Web of Science ®Google Scholar
• Wasser , S. , Ho , J. M. , Ang , H. K. and Tan , C. E. 1998 . Salvia miltiorrhiza reduces experimentally‐induced hepatic fibrosis in rats . J. Hepatol. , 29 ( 5 ) : 760 – 771 .
   PubMed Web of Science ®Google Scholar
• Chae , H. J. , Chae , S. W. , Yun , D. H. , Keum , K. S. , Yoo , S. K. and Kim , H. R. 2004 . Prevention of boneloss in ovariectomized rats: the effect of Salvia miltiorrhiza extracts . Immunopharmal. Immunotoxicol. , 26 ( 1 ) : 135 – 144 .
   PubMed Web of Science ®Google Scholar
• Lin , Y. H. , Liu , A. H. , Wu , H. L. , Westenbroek , C. , Song , Q. L. , Yu , H. M. , Ter Horst , G. J. and Li , X. J. 2006 . Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents Aβ25–35‐induced reduction in BPRP in PC12 cells. Biochem . Biophys. Res. Commun. , 348 ( 2 ) : 593 – 599 .
   PubMed Web of Science ®Google Scholar
• Kim , H. H. , Kim , J. H. , Kwak , H. B. , Huang , H. , Han , S. H. , Ha , H. , Lee , S. W. , Woo , E. R. and Lee , Z. H. 2004 . Inhibition of osteoclast differentiation and bone resorption by tanshinone IIA isolated from. Salvia miltiorrhiza Bunge . Biochem. Pharmacol. , 67 ( 9 ) : 1647 – 1656 .
   PubMed Web of Science ®Google Scholar
• Fan , Z. 2005 . A survey of treatment of diabetic complications with Chinese drugs . J. Tradit. Chinese Med. , 25 ( 2 ) : 153 – 159 .
   PubMedGoogle Scholar
• Yue , K. K.M. , Lee , K. , Chan , K. K.C. , Leung , K. S.Y. , Leung , A. W.N. and Cheng , C. H.K. 2006 . Danshen prevents the occurrence of oxidative stress in the eye and aorta of diabetic rats without affecting the hyperglycemic state . J. Ethnopharmacol. , 106 ( 1 ) : 136 – 141 .
   PubMed Web of Science ®Google Scholar
• Honda , G. , Koezuka , Y. and Tabata , M. 1988 . Isolation of an antidermatophytic substance from the root of Salvia miltiorrhiza . Chem. Pharmaceut. Bull. , 36 ( 1 ) : 408 – 411 .
   PubMed Web of Science ®Google Scholar
• Wang , X. , Bastow , K. F. , Sun , C. M. , Lin , Y. L. , Yu , H. J. , Don , M. J. , Wu , T. S. , Nakamura , S. and Lee , K. H. 2004 . Antitumor agents. 239. Isolation, structure elucidation, total synthesis, and anti‐breast cancer activity of neo‐tanshinlactone from Salvia miltiorrhiza . J. Med. Chem. , 47 ( 23 ) : 5816 – 5819 .
   PubMed Web of Science ®Google Scholar
• Ji , X. Y. , Tan , B. K.H. , Zhu , Y. C. , Linz , W. and Zhu , Y. Z. 2003 . Comparison of cardioprotective effects using ramipril and DanShen for the treatment of acute myocardial infarction in rats . Life Sci. , 73 ( 11 ) : 1413 – 1426 .
   PubMed Web of Science ®Google Scholar
• Ji , X. Y. , Tan , B. K. and Zhu , Y. Z. 2000 . Salvia miltiorrhiza and ischemic diseases . Acta Pharmacol. Sinica , 21 ( 12 ) : 1089 – 1094 .
   PubMed Web of Science ®Google Scholar
• Wang , H. , Gao , X. M. and Zhang , B. L. 2005 . Tanshinone: An inhibitor of proliferation of vascular smooth muscle cells . J. Ethnopharmaco. , 99 ( 1 ) : 93 – 98 .
   PubMed Web of Science ®Google Scholar
• Zhang , M. , Li , X. , Jiu , G. Q. and Liu , Y. 2003 . Effect of Danshen Injection on Expression of platelet membrane glycoproteins in patients with type II diabetes mellitus . J. Chinese Med. Mat. , 26 ( 10 ) : 738 – 740 .
   Google Scholar
• Luo , X. J. , Bi , K. S. , Zhou , S. Y. , Wei , Q. H. and Zhang , R. H. 2001 . Determination of Danshensu, a major active compound of Radix Salvia miltiorrhiza in dog plasma by HPLC with fluorescence detection . Biomed. Chromatogr. , 15 ( 8 ) : 493 – 496 .
   PubMed Web of Science ®Google Scholar
• Zhou , L. Y. and Zhu , X. X. 2005 . Progresses in studies of the pharmacokinetics of Danshen and its chemical components . Chinese J. Exptl. Tradit. Med. Formul. , 11 ( 3 ) : 66 – 69 .
   Google Scholar
• Ng , T. B. , Liu , F. and Wang , Z. T. 2000 . Antioxidative activity of natural products from plants . Life Sci. , 66 ( 8 ) : 709 – 723 .
   PubMed Web of Science ®Google Scholar
• Du , J. R. , Li , X. , Zhang , R. and Qian , Z. M. 2005 . Tanshinone inhibits intimal hyperplasia in the ligated carotid artery in mice . J. Ethnopharmacol. , 98 ( 3 ) : 319 – 322 .
   PubMed Web of Science ®Google Scholar
• An , R. , Wang , X. H. , Tang , Y. and Zhang , J. Z. 2005 . Comparision of water soluble component in Danshen from different sources . Chinese Tradit. Patent Med. , 27 ( 7 ) : 812 – 815 .
   Google Scholar
• Zhou , C. X. , Luo , H. W. and Niwa , M. 1999 . Studies on isolation and identification of water soluble constituents of salvia miltiorrhiza . J. China Pharmaceut. Univ. , 30 ( 6 ) : 411 – 416 .
   Google Scholar
• Du , G. H. and Zhang , J. T. 2000 . The pharmacological effects of salvianolic acids and the mechanisms of their actions are reviewed . Basic Med. Sci. Clinics , 20 ( 5 ) : 394 – 398 .
   Google Scholar
• Tang , M. K. , Ren , D. C. , Zhang , J. T. and Du , G. H. 2002 . Effect of salvianolic acids from Radix Salviae miltiorrhizae on regional cerebral blood flow and platelet aggregation in rats . Phytomedicine , 9 ( 5 ) : 405 – 409 .
   PubMed Web of Science ®Google Scholar
• Lin , S. J. 1998 . The effects of antioxidant from Chinese medicinal herb on intimal hyperplasia in restenosis animal model . Atherosclerosis , 136 ( 1 ) : S34
   Web of Science ®Google Scholar
• Wu , Y. J. , Hong , C. Y. , Lin , S. J. , Wu , P. and Shiao , M. S. 1998 . Increase of vitamin E content in LDL and reduction of atherosclerosis in cholesterol‐fed rabbits by a water soluble antioxidant‐rich fraction of Salvia miltiorrhiza . Arter. Thromb. Vasc. Biol. , 18 ( 3 ) : 481 – 486 .
   PubMed Web of Science ®Google Scholar
• Lu , Y. R. and Foo , L. Y. 2002 . Polyphenolics of Salvia—a review . Phytochemistry , 59 ( 2 ) : 117 – 140 .
   PubMed Web of Science ®Google Scholar
• Luo , X. J. , Bi , K. S. , Zhou , S. Y. and Zhang , R. H. 2001 . A brief account of the study on fufangdashen tablets . Chinese Tradit. Patent Med. , 23 ( 50 ) : 371 – 374 .
   Google Scholar
• Ma , L. J. , Zhang , X. Z. , Guo , H. and Gan , Y. 2006 . Determination of four water soluble compounds in Salvia miltiorrhiza Bunge by high‐performance liquid chromatography with a coulometric electrode array system . J. Chromatogr. B. , 833 ( 2 ) : 260 – 263 .
   PubMed Web of Science ®Google Scholar
• Zhao , B. L. , Jiang , W. , Zhao , Y. , Hou , J. W. and Xin , W. J. 1996 . Scavenging effects of salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia‐reperfusion injury . Biochem. Molec. Biol. Intl. , 38 ( 6 ) : 1171 – 1182 .
   PubMedGoogle Scholar
• Jiang , Y. L. , Li , W. , Zhuang , Z. X. , Frank , S. C.L. and Wang , X. R. 2005 . Quality assessment of radix Salvia Miltiorrhiza (Danshen) by TLC fingerprinting technique . J. of Xiamen Univ. (Nat. Sci.). , 44 ( 6 ) : 801 – 805 .
   Google Scholar
• Hu , X. W. and Zhao , Q. W. 2002 . Determination of protocatechuic acid, protocatechualdehyde in Fen Han Gan Mao Ning granules by RP‐HPLC . Chinese J. Mod. Appl. Pharm. , 19 ( 1 ) : 53 – 56 .
   Google Scholar
• Zhang , J. L. , Cui , M. , He , Y. , Yu , H. L. and Guo , D. A. 2005 . Chemical fingerprint and metabolic fingerprint analysis of Danshen injection by HPLC–UV and HPLC–MS methods . J. Pharmaceut. Biomed. Anal. , 36 ( 5 ) : 1029 – 1035 .
   PubMed Web of Science ®Google Scholar
• Hu , P. , Liang , Q. L. , Luo , G. A. , Zhao , Z. Z. and Jiang , Z. H. 2005 . Multi‐component HPLC fingerprinting of Radix Salviae Miltiorrhizae and its LC‐MS‐MS identification . Chem. Pharmaceut. Bull. (Tokyo) , 53 ( 6 ) : 677 – 683 .
   PubMed Web of Science ®Google Scholar
• Simonet , B. M. , Ríos , A. and Valcárcel , M. 2003 . Enhancing sensitivity in capillary electrophoresis . Trends Anal. Chem. , 22 ( 10 ) : 605 – 614 .
   Web of Science ®Google Scholar
• Yin , C. and Wu , Y. T. 1999 . Research of high performance capillary electrophoresis for analysis of Chinese herbal drugs . Chinese J. Pharmaceut. Anal. , 19 ( 3 ) : 209 – 216 .
   Google Scholar
• Pan , Y. L. , Zhang , L. and Chen , G. N. 2001 . Separation and determination of protocatechuic aldehyde and protocatechuic acid in Salivia miltorrhrza by capillary electrophoresis with amperometric detection . Analyst. , 126 ( 9 ) : 1519 – 1523 .
   PubMed Web of Science ®Google Scholar
• Han , S. Q. , Liu , E. B. and Li , H. 2005 . On‐line chemiluminescence determination protocatechuic aldehyde and protocatechuic acid in pharmaceutical preparations by capillary electrophoresis . J. Pharmaceut. Biomed. Anal. , 37 ( 4 ) : 733 – 738 .
   PubMed Web of Science ®Google Scholar